Marjoke Heneweer

Summary

Affiliation: Institute for Risk Assessment Sciences
Country: The Netherlands

Publications

  1. ncbi A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase
    Marjoke Heneweer
    Institute for Risk Assessment Sciences, Nieuw Gildestein, P O Box 80176, 3508 TD Utrecht, The Netherlands
    Toxicol Lett 146:183-94. 2004
  2. ncbi Co-culture of primary human mammary fibroblasts and MCF-7 cells as an in vitro breast cancer model
    Marjoke Heneweer
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Toxicol Sci 83:257-63. 2005
  3. ncbi Inhibition of aromatase activity by methyl sulfonyl PCB metabolites in primary culture of human mammary fibroblasts
    Marjoke Heneweer
    Institute for Risk Assessment Sciences, Utrecht University, 3508 TD Utrecht, The Netherlands
    Toxicol Appl Pharmacol 202:50-8. 2005
  4. ncbi Additive estrogenic effects of mixtures of frequently used UV filters on pS2-gene transcription in MCF-7 cells
    Marjoke Heneweer
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Toxicol Appl Pharmacol 208:170-7. 2005
  5. ncbi The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans
    Bas J Blaauboer
    Institute for Risk Assessment Sciences, Division of Toxicology, Utrecht University, The Netherlands
    ALTEX 29:411-25. 2012
  6. doi Subacute effects of hexabromocyclododecane (HBCD) on hepatic gene expression profiles in rats
    Rocío F Cantón
    Institute for Risk Assessment Sciences IRAS, Utrecht University, P O Box 80 177, NL 3508 TD, Utrecht, The Netherlands
    Toxicol Appl Pharmacol 231:267-72. 2008

Detail Information

Publications6

  1. ncbi A comparison of human H295R and rat R2C cell lines as in vitro screening tools for effects on aromatase
    Marjoke Heneweer
    Institute for Risk Assessment Sciences, Nieuw Gildestein, P O Box 80176, 3508 TD Utrecht, The Netherlands
    Toxicol Lett 146:183-94. 2004
    ..The R2C cell line, although not suitable for studying induction, appears to be a more sensitive cell line for studying inhibitory effects of xenobiotics on aromatase activity...
  2. ncbi Co-culture of primary human mammary fibroblasts and MCF-7 cells as an in vitro breast cancer model
    Marjoke Heneweer
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Toxicol Sci 83:257-63. 2005
    ..This co-culture provides a more sophisticated and sensitive system to detect direct and indirect estrogenic effects of compounds and their possible effects on breast tumor promotion...
  3. ncbi Inhibition of aromatase activity by methyl sulfonyl PCB metabolites in primary culture of human mammary fibroblasts
    Marjoke Heneweer
    Institute for Risk Assessment Sciences, Utrecht University, 3508 TD Utrecht, The Netherlands
    Toxicol Appl Pharmacol 202:50-8. 2005
    ..We conclude that in primary human mammary fibroblasts as well as in H295R cells, aromatase inhibition by MeSO(2)-PCBs is likely to be due to catalytic inhibition...
  4. ncbi Additive estrogenic effects of mixtures of frequently used UV filters on pS2-gene transcription in MCF-7 cells
    Marjoke Heneweer
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Toxicol Appl Pharmacol 208:170-7. 2005
    ..In view of our results and observed plasma levels it cannot be excluded that daily exposure to sunscreen formulations may have estrogenic effects in humans...
  5. ncbi The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans
    Bas J Blaauboer
    Institute for Risk Assessment Sciences, Division of Toxicology, Utrecht University, The Netherlands
    ALTEX 29:411-25. 2012
    ..Moreover, data selection and integration need to be driven by their usefulness in a quantitative in vitro-in vivo extrapolation (QIVIVE)...
  6. doi Subacute effects of hexabromocyclododecane (HBCD) on hepatic gene expression profiles in rats
    Rocío F Cantón
    Institute for Risk Assessment Sciences IRAS, Utrecht University, P O Box 80 177, NL 3508 TD, Utrecht, The Netherlands
    Toxicol Appl Pharmacol 231:267-72. 2008
    ..g. decreased thyroid hormone or increased serum cholesterol levels). To our knowledge, this is the fist study that describes the changes in rat hepatic gene profiles caused by this commonly used flame retardant...