Bert Brunekreef

Summary

Affiliation: Institute for Risk Assessment Sciences
Country: The Netherlands

Publications

  1. doi Health effects of air pollution observed in cohort studies in Europe
    Bert Brunekreef
    Department of Environmental Epidemiology, Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, Universiteit Utrecht, PO Box 80178, Utrecht 3508 TD, The Netherlands
    J Expo Sci Environ Epidemiol 17:S61-5. 2007
  2. pmc Meeting report: national workshops for the communication of air pollution and health information: summary of four workshops in different regions of Europe
    Eric Gordon Sanderson
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Environ Health Perspect 114:1108-12. 2006
  3. pmc Do parents who smoke underutilize health care services for their children? A cross sectional study within the longitudinal PIAMA study
    Monique A M Jacobs-van der Bruggen
    National Institute of Public Health and the Environment RIVM, Bilthoven, The Netherlands
    BMC Health Serv Res 7:83. 2007
  4. ncbi Epidemiological evidence of effects of coarse airborne particles on health
    B Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Eur Respir J 26:309-18. 2005
  5. ncbi The brave new world of lives sacrificed and saved, deaths attributed and avoided
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands
    Epidemiology 18:785-8. 2007
  6. ncbi After the wall
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Epidemiology 13:376-8. 2002
  7. pmc Out of Africa
    B Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, Netherlands
    Occup Environ Med 62:351-2. 2005
  8. ncbi [The dangers to health of fine dust particles in the air]
    B Brunekreef
    Universiteit Utrecht, Institute for Risk Assessment Sciences, Postbus 80 178, 3508 TD Utrecht
    Ned Tijdschr Geneeskd 150:710-2. 2006
  9. ncbi He who pays the piper, calls the tune
    Bert Brunekreef
    University of Utrecht Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Epidemiology 17:246-7. 2006
  10. ncbi The prevention and incidence of asthma and mite allergy (PIAMA) birth cohort study: design and first results
    Bert Brunekreef
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Pediatr Allergy Immunol 13:55-60. 2002

Detail Information

Publications147 found, 100 shown here

  1. doi Health effects of air pollution observed in cohort studies in Europe
    Bert Brunekreef
    Department of Environmental Epidemiology, Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, Universiteit Utrecht, PO Box 80178, Utrecht 3508 TD, The Netherlands
    J Expo Sci Environ Epidemiol 17:S61-5. 2007
    ..The results of a number of recent European studies are discussed...
  2. pmc Meeting report: national workshops for the communication of air pollution and health information: summary of four workshops in different regions of Europe
    Eric Gordon Sanderson
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Environ Health Perspect 114:1108-12. 2006
    ..Because a broad stakeholder involvement in decision making can positively affect the development of widely supported policies, such meetings should be continued for Europe and elsewhere...
  3. pmc Do parents who smoke underutilize health care services for their children? A cross sectional study within the longitudinal PIAMA study
    Monique A M Jacobs-van der Bruggen
    National Institute of Public Health and the Environment RIVM, Bilthoven, The Netherlands
    BMC Health Serv Res 7:83. 2007
    ..This study explores the validity and generalizability of the previous assumption...
  4. ncbi Epidemiological evidence of effects of coarse airborne particles on health
    B Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Eur Respir J 26:309-18. 2005
    ..There is also support for an association between coarse PM and cardiovascular admissions. It is concluded that special consideration should be given to studying and regulating coarse particles separately from fine particles...
  5. ncbi The brave new world of lives sacrificed and saved, deaths attributed and avoided
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, Utrecht University, Utrecht, The Netherlands
    Epidemiology 18:785-8. 2007
    ....
  6. ncbi After the wall
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Epidemiology 13:376-8. 2002
  7. pmc Out of Africa
    B Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD Utrecht, Netherlands
    Occup Environ Med 62:351-2. 2005
  8. ncbi [The dangers to health of fine dust particles in the air]
    B Brunekreef
    Universiteit Utrecht, Institute for Risk Assessment Sciences, Postbus 80 178, 3508 TD Utrecht
    Ned Tijdschr Geneeskd 150:710-2. 2006
    ..It is far more likely that such insight will be used for specific source policy aimed at tackling the sources that contribute the most to the harmfulness of the mixture of air pollution...
  9. ncbi He who pays the piper, calls the tune
    Bert Brunekreef
    University of Utrecht Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Epidemiology 17:246-7. 2006
  10. ncbi The prevention and incidence of asthma and mite allergy (PIAMA) birth cohort study: design and first results
    Bert Brunekreef
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Pediatr Allergy Immunol 13:55-60. 2002
    ....
  11. ncbi Air pollution and health
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80176, 3508 TD, Utrecht, Netherlands
    Lancet 360:1233-42. 2002
    ..In this review, we discuss the evidence for adverse effects on health of selected air pollutants...
  12. doi Traffic-related air pollution is related to interrupter resistance in 4-year-old children
    Esther Eenhuizen
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Eur Respir J 41:1257-63. 2013
    ....
  13. ncbi Childhood cat allergen exposure in three European countries: The AIRALLERG study
    Mariëlla Giovannangelo
    Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Sci Total Environ 369:82-90. 2006
    ..Cat allergen is a major cause of morbidity among sensitised asthma patients, but little is known about distribution of cat allergen exposure and its determinants in homes...
  14. ncbi Impact of low emission zones and local traffic policies on ambient air pollution concentrations
    Hanna Boogaard
    Institute for Risk Assessment Sciences IRAS, Division Environmental Epidemiology, Utrecht University, Utrecht, Netherlands
    Sci Total Environ 435:132-40. 2012
    ..This study investigated air pollution at street level before and after implementation of local traffic policies including low emission zones (LEZ) directed at heavy duty vehicles (trucks) in five Dutch cities...
  15. doi Respiratory effects of a reduction in outdoor air pollution concentrations
    Hanna Boogaard
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, Netherlands
    Epidemiology 24:753-61. 2013
    ..We assessed whether a reduction in (traffic policy-related) air pollution concentrations was associated with changes in respiratory health...
  16. doi Traffic-related air pollution and the development of asthma and allergies during the first 8 years of life
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, The Netherlands
    Am J Respir Crit Care Med 181:596-603. 2010
    ..The role of air pollution exposure in the development of asthma, allergies, and related symptoms remains unclear, due in part to the limited number of prospective cohort studies with sufficiently long follow-ups addressing this problem...
  17. ncbi Time in bed, sleep quality and associations with cardiometabolic markers in children: the Prevention and Incidence of Asthma and Mite Allergy birth cohort study
    Nina E Berentzen
    Center for Nutrition, Prevention, and Health Services, National Institute for Public Health and the Environment, Bilthoven, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    J Sleep Res 23:3-12. 2014
    ..Therefore, we consider it premature to propose that improved sleep could reduce cardiovascular risk during childhood...
  18. doi Gas cooking, respiratory and allergic outcomes in the PIAMA birth cohort study
    WeiWei Lin
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 70:187-94. 2013
    ..Our aim was to examine the association between gas cooking and the development of respiratory and allergic outcomes longitudinally in a prospective birth cohort study...
  19. pmc Contrasts in oxidative potential and other particulate matter characteristics collected near major streets and background locations
    Hanna Boogaard
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 120:185-91. 2012
    ..Measuring the oxidative potential of airborne particulate matter (PM) may provide a more health-based exposure measure by integrating various biologically relevant properties of PM into a single predictor of biological activity...
  20. doi Overweight and changes in weight status during childhood in relation to asthma symptoms at 8 years of age
    Salome Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    J Allergy Clin Immunol 123:1312-8.e2. 2009
    ..Asthma may be more prevalent in overweight children. However, how early overweight and changes in weight status during childhood affect the asthma risk is unclear...
  21. doi Waist circumference, BMI, and lung function in 8-year-old children: the PIAMA birth cohort study
    Marga B M Bekkers
    Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Pediatr Pulmonol 48:674-82. 2013
    ..Body mass index (BMI) and waist circumference (WC) may be associated with lung function in children, as observed in adults...
  22. doi Do differences in childhood diet explain the reduced overweight risk in breastfed children?
    Salome Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Obesity (Silver Spring) 16:2498-503. 2008
    ..71, 95% confidence interval: 0.49-1.03). Breastfed children had a healthier diet at 7 years compared to nonbreastfed children, but this difference could not explain the lower overweight risk at 8 years in breastfed children...
  23. ncbi Levels and determinants of beta(1-->3)-glucans and fungal extracellular polysaccharides in house dust of (pre-)school children in three European countries
    Mariëlla E C A Giovannangelo
    Utrecht University, Institute for Risk Assessment Sciences, Utrecht, The Netherlands
    Environ Int 33:9-16. 2007
    ..Measurements of beta(1-->3)-glucans and fungal extracellular polysaccharides (EPS) are used as markers of mold exposure in field studies. Little is known about their levels and determinants in homes...
  24. doi Asthma therapy during the first 8 years of life: a PIAMA cohort study
    Mira G P Zuidgeest
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Faculty of Science, Utrecht University, 3508 TB Utrecht, The Netherlands
    J Asthma 47:209-13. 2010
    ..This study describes the formation of a longitudinal data set on asthma medication use and shows first results regarding the prevalence and incidence of medication use...
  25. doi High agreement between parental reported inhaled corticosteroid use and pharmacy prescription data
    Ellen S Koster
    Division of Pharmacoepidemiology and Pharmacotherapy, Faculty of Science, Utrecht Institute for Pharmaceutical Sciences UIPS, Utrecht University, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 19:1199-203. 2010
    ..This study was conducted to assess the validity of parental reported use of inhaled corticosteroids (ICS) in children...
  26. pmc What drives prescribing of asthma medication to children? A multilevel population-based study
    Mira G P Zuidgeest
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Faculty of Science, Utrecht University, Utrecht, The Netherlands
    Ann Fam Med 7:32-40. 2009
    ..This challenge creates an opportunity for variability in prescribing. The aim of our study was to investigate how and to what degree patient, family, and physician characteristics influence prescribing of asthma medication in children...
  27. doi Traffic-related air pollution, preterm birth and term birth weight in the PIAMA birth cohort study
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, PO Box 80178, 3508 TD Utrecht, The Netherlands
    Environ Res 111:125-35. 2011
    ..Maternal exposure to air pollution has been associated with adverse pregnancy outcomes. Few studies took into account the spatial and temporal variation of air pollution levels...
  28. doi Uncontrolled asthma at age 8: the importance of parental perception towards medication
    Ellen S Koster
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Faculty of Science, Utrecht University, Utrecht, The Netherlands
    Pediatr Allergy Immunol 22:462-8. 2011
    ..The aim of this study was to identify determinants of uncontrolled asthma at age 8 in children participating in the PIAMA birth cohort study...
  29. doi Patterns of asthma medication use: early asthma therapy initiation and asthma outcomes at age 8
    Ellen S Koster
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Faculty of Science, Utrecht University, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 19:991-9. 2010
    ..ICS and SABA prescription occurs especially in those who were more likely to develop signs of asthma at age 8...
  30. doi Traffic-related outdoor air pollution and respiratory symptoms in children: the impact of adjustment for exposure measurement error
    Sofie van Roosbroeck
    Environmental Epidemiology Group, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Epidemiology 19:409-16. 2008
    ..Outdoor concentrations of soot and nitrogen dioxide (NO2) outside of schools have been associated with children's respiratory and eye symptoms. We assessed how adjustments for measurement error affect these associations...
  31. ncbi Long-term exposure to elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts: results from the ESCAPE and TRANSPHORM projects
    Meng Wang
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands Electronic address
    Environ Int 66:97-106. 2014
    ..However, health effects of long-term exposure to constituents of PM on total CVD mortality have been explored in a single study only...
  32. pmc BMI development of normal weight and overweight children in the PIAMA study
    Saskia M Willers
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 7:e39517. 2012
    ..There is evidence that rapid weight gain during the first year of life is associated with overweight later in life. However, results from studies exploring other critical periods for the development of overweight are inconsistent...
  33. doi Blood pressure in 12-year-old children is associated with fatty acid composition of human milk: the prevention and incidence of asthma and mite allergy birth cohort
    Lenie van Rossem
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    Hypertension 60:1055-60. 2012
    ....
  34. ncbi Variation of biocontaminant levels within and between homes--the AIRALLERG study
    Mariëlla Giovannangelo
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    J Expo Sci Environ Epidemiol 17:134-40. 2007
    ..Investigation of variation over time is needed for a more complete assessment of the use of these variables in epidemiological analyses of exposure-response relationships...
  35. ncbi Long-term exposure to traffic-related air pollution and lung cancer risk
    Rob Beelen
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Epidemiology 19:702-10. 2008
    ..Most studies on the association between lung cancer and air pollution have investigated mortality. There have been few studies of lung cancer incidence...
  36. ncbi Exposure to cats and dogs, and symptoms of asthma, rhinoconjunctivitis, and eczema
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, University Medical Center Universiteit Utrecht, The Netherlands
    Epidemiology 23:742-50. 2012
    ..Associations between exposure to cats and dogs and respiratory and allergic outcomes in children have been reported in affluent countries, but little is known about such associations in less-affluent countries...
  37. doi Persistence of asthma medication use in preschool children
    Mira G Zuidgeest
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, P O BOX 80082, 3508 TB, Utrecht, The Netherlands
    Respir Med 102:1446-51. 2008
    ..Our aim is to quantify the persistent use of asthma medication, initiated in the first year of life and identify determinants of this persistent use...
  38. pmc Mite and pet allergen levels in homes of children born to allergic and nonallergic parents: the PIAMA study
    Rob T van Strien
    Department of Environmental and Occupational Health, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 110:A693-8. 2002
    ..Parental mattresses in homes of allergic mothers had lower cat and mite (but not dog) allergen loadings than mattresses in homes of nonallergic parents. Paternal (as opposed to maternal) allergy seemed to have little influence...
  39. ncbi Relationship between different size classes of particulate matter and meteorology in three European cities
    Jeroen J de Hartog
    Utrecht University, Institute for Risk Assessment Sciences, Environmental and Occupational Health Division, Jenalaan 18a, 3584 CK Utrecht, The Netherlands
    J Environ Monit 7:302-10. 2005
    ..Since the composition of these particle fractions also differs, it is of interest to test in future epidemiological studies whether they have different health effects...
  40. pmc BMI and waist circumference; cross-sectional and prospective associations with blood pressure and cholesterol in 12-year-olds
    Marga B M Bekkers
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 7:e51801. 2012
    ..We studied associations between BMI and WC and blood pressure (BP) and cholesterol in 12-year-old children and prospectively changes in BMI or WC status between age 8 and 12 years and BP and cholesterol at age 12...
  41. doi Systematic evaluation of land use regression models for NO₂
    Meng Wang
    Institute for Risk Assessment Sciences IRAS, Division of Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Sci Technol 46:4481-9. 2012
    ..In our specific application, models based on as few as 24 training sites, however, achieved acceptable hold out validation R(2)s of, on average, 0.60...
  42. doi Land use regression model for ultrafine particles in Amsterdam
    Gerard Hoek
    Institute for Risk Assessment Sciences IRAS, Division of Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Sci Technol 45:622-8. 2011
    ..5, soot, and coarse particles. A LUR model for PNC has been developed, with similar validity as previous models for more commonly measured pollutants...
  43. pmc Environmental exposure assessment in European birth cohorts: results from the ENRIECO project
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Health 12:8. 2013
    ....
  44. doi Effect of endotoxin and allergens on neonatal lung function and infancy respiratory symptoms and eczema
    Victoria Abbing-Karahagopian
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Pediatr Allergy Immunol 23:448-55. 2012
    ..Exposure to endotoxin and allergens in house dust has been found to be associated with childhood wheeze and asthma. Neonatal lung function is rarely examined in relation to this exposure...
  45. pmc Early-life determinants of total and HDL cholesterol concentrations in 8-year-old children; the PIAMA birth cohort study
    Marga B M Bekkers
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 6:e25533. 2011
    ....
  46. doi Long-chain polyunsaturated fatty acids in breast milk and early weight gain in breast-fed infants
    Salome Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, The Netherlands
    Br J Nutr 101:116-21. 2009
    ..The n-3 and n-6 LCPUFA content in breast milk did not affect weight or BMI gain in the first year of life in breast-fed term infants...
  47. doi Parental reported compared with measured waist circumference in 8-year-old children
    Marga B M Bekkers
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Int J Pediatr Obes 6:e78-86. 2011
    ..In this study the agreement between parental reported and measured WC in 8-year-old children was investigated and compared with the agreement between parental reported and measured body mass index (BMI)...
  48. pmc Long-term effects of traffic-related air pollution on mortality in a Dutch cohort (NLCS-AIR study)
    Rob Beelen
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 116:196-202. 2008
    ..Several studies have found an effect on mortality of between-city contrasts in long-term exposure to air pollution. The effect of within-city contrasts is still poorly understood...
  49. doi Respiratory health effects of ultrafine and fine particle exposure in cyclists
    Maciej Strak
    Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, PO Box 80178, 3508 TD Utrecht, The Netherlands
    Occup Environ Med 67:118-24. 2010
    ..We carried out a study to investigate the acute respiratory health effects of air pollution related to commuting by bicycle...
  50. pmc The relationship between air pollution from heavy traffic and allergic sensitization, bronchial hyperresponsiveness, and respiratory symptoms in Dutch schoolchildren
    Nicole A H Janssen
    Department of Environmental Epidemiology, Institute for Risk Assessment Sciences, University of Utrecht, PO Box 80176, 3508 TD Utrecht, The Netherlands
    Environ Health Perspect 111:1512-8. 2003
    ....
  51. doi Maternal food consumption during pregnancy and the longitudinal development of childhood asthma
    Saskia M Willers
    Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, P O Box 80178, 3508 TD Utrecht, The Netherlands
    Am J Respir Crit Care Med 178:124-31. 2008
    ..Maternal diet during pregnancy has the potential to affect airway development and to promote T-helper-2-cell responses during fetal life. This might increase the risk of developing childhood asthma or allergy...
  52. ncbi Long-term exposure to air pollution and vascular damage in young adults
    Virissa Lenters
    Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Epidemiology 21:512-20. 2010
    ..There are, however, very limited data in healthy young people. We examined the association between air pollutants and indicators of vascular damage in a cohort of young adults...
  53. ncbi Exposure to microbial components and allergens in population studies: a comparison of two house dust collection methods applied by participants and fieldworkers
    D Schram-Bijkerk
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Indoor Air 16:414-25. 2006
    ....
  54. ncbi Comparison of ambient airborne PM₂.₅, PM₂.₅ absorbance and nitrogen dioxide ratios measured in 1999 and 2009 in three areas in Europe
    John L Durant
    Institute for Risk Assessment Sciences IRAS, Division of Environmental Epidemiology, University of Utrecht, Utrecht, The Netherlands Department of Civil and Environmental Engineering, Tufts University, Medford, MA, USA Electronic address
    Sci Total Environ 487:290-8. 2014
    ..The changed contrasts may affect estimates of health effects related to NO2 as a marker of proximity to roads...
  55. doi Evaluation of land use regression models for NO2 and particulate matter in 20 European study areas: the ESCAPE project
    Meng Wang
    Institute for Risk Assessment Sciences, Utrecht University, P O Box 80178, 3508 TD Utrecht, The Netherlands
    Environ Sci Technol 47:4357-64. 2013
    ..Nevertheless, in most areas LUR models still explained a substantial fraction of the variation of concentrations measured at independent sites...
  56. doi Agreement of land use regression models with personal exposure measurements of particulate matter and nitrogen oxides air pollution
    Denise Montagne
    Institute for Risk Assessment Sciences IRAS, University of Utrecht, Utrecht, The Netherlands
    Environ Sci Technol 47:8523-31. 2013
    ..This study supports the use of intraurban LUR models for especially soot in air pollution epidemiology. ..
  57. doi Air pollution exposure affects circulating white blood cell counts in healthy subjects: the role of particle composition, oxidative potential and gaseous pollutants - the RAPTES project
    Maaike Steenhof
    Division of Toxicology and Division of Environmental Epidemiology, Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Inhal Toxicol 26:141-65. 2014
    ..Future studies should indicate if air pollution exposure-induced changes in blood cell counts results in adverse cardiovascular effects in susceptible individuals...
  58. doi Early life exposure to farm animals and symptoms of asthma, rhinoconjunctivitis and eczema: an ISAAC Phase Three Study
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, University Medical Center Universiteit Utrecht, Utrecht, The Netherlands
    Int J Epidemiol 41:753-61. 2012
    ..Associations between early life exposure to farm animals and respiratory symptoms and allergy in children have been reported in developed countries, but little is known about such associations in developing countries...
  59. ncbi Breastfeeding, weight gain in infancy, and overweight at seven years of age: the prevention and incidence of asthma and mite allergy birth cohort study
    Salome Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Am J Epidemiol 165:919-26. 2007
    ..These findings suggest that the lower BMI and lower risk of overweight among breastfed children later in life are already achieved at 1 year of age...
  60. ncbi Estimating long-term average particulate air pollution concentrations: application of traffic indicators and geographic information systems
    Michael Brauer
    Utrecht University, Institute for Risk Assessment Sciences, Environmental and Occupational Health Group, Utrecht, The Netherlands
    Epidemiology 14:228-39. 2003
    ....
  61. doi Air pollution and exhaled nitric oxide in Dutch schoolchildren
    Haitske Graveland
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 68:551-6. 2011
    ..No studies have simultaneously addressed the long-term and short-term associations between traffic-related air pollution and exhaled NO...
  62. doi Stability of measured and modelled spatial contrasts in NO(2) over time
    Marloes Eeftens
    Institute for Risk Assessment Sciences IRAS, Utrecht University, PO Box 80178, 3508 TD Utrecht, The Netherlands
    Occup Environ Med 68:765-70. 2011
    ..We tested the stability of measured and modelled spatial contrasts in outdoor nitrogen dioxide (NO(2)) pollution across the Netherlands over 8 years...
  63. pmc Self-reported truck traffic on the street of residence and symptoms of asthma and allergic disease: a global relationship in ISAAC phase 3
    Bert Brunekreef
    Institute for Risk Assessment Sciences and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Environ Health Perspect 117:1791-8. 2009
    ..Associations between traffic pollution on the street of residence and a range of respiratory and allergic outcomes in children have been reported in developed countries, but little is known about such associations in developing countries...
  64. doi Traffic-related air pollution and pregnancy outcomes in the Dutch ABCD birth cohort study
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, 3508 TD Utrecht, The Netherlands
    Occup Environ Med 68:36-43. 2011
    ..As European data on this topic are limited, the aim of this study was to evaluate the impact of maternal exposure to traffic-related air pollution during different periods of pregnancy on preterm birth and fetal growth...
  65. ncbi Long-term personal exposure to traffic-related air pollution among school children, a validation study
    Sofie van Roosbroeck
    Institute for Risk Assessment Sciences, Utrecht University, P O Box 80176, 3508 TD Utrecht, The Netherlands
    Sci Total Environ 368:565-73. 2006
    ..This finding supports the use of 'living near a busy road' as a measure of exposure in epidemiological studies on the effects of traffic-related air pollution in children...
  66. ncbi Gas cooking, kitchen ventilation, and asthma, allergic symptoms and sensitization in young children--the PIAMA study
    S M Willers
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Allergy 61:563-8. 2006
    ..The aim of this study was to investigate the effect of kitchen ventilation (while cooking) on the relationship between gas cooking, combustion product dispersal, and respiratory and allergic outcomes in children...
  67. pmc Associations between ambient, personal, and indoor exposure to fine particulate matter constituents in Dutch and Finnish panels of cardiovascular patients
    N A H Janssen
    Division of Environmental and Occupational Health, Institute for Risk Assessment Sciences IRAS, Utrecht University, The Netherlands
    Occup Environ Med 62:868-77. 2005
    ..To assess the relation between ambient, indoor, and personal levels of PM2.5 and its elemental composition for elderly subjects with cardiovascular disease...
  68. doi Development of Land Use Regression models for PM(2.5), PM(2.5) absorbance, PM(10) and PM(coarse) in 20 European study areas; results of the ESCAPE project
    Marloes Eeftens
    Institute for Risk Assessment Sciences, Utrecht University, P O Box 80178, 3508 TD Utrecht, The Netherlands
    Environ Sci Technol 46:11195-205. 2012
    ..The final LUR models are used to estimate air pollution concentrations at the home addresses of participants in the health studies involved in ESCAPE...
  69. pmc Composition of PM affects acute vascular inflammatory and coagulative markers - the RAPTES project
    Maciej Strak
    Centre for Environmental Health MGO, National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
    PLoS ONE 8:e58944. 2013
    ..Exposure to ambient particulate matter (PM) has been associated with adverse cardiovascular effects in epidemiological studies. Current knowledge of independent effects of individual PM characteristics remains limited...
  70. pmc Evaluation of a low-cost electrostatic dust fall collector for indoor air endotoxin exposure assessment
    Ilka Noss
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Appl Environ Microbiol 74:5621-7. 2008
    ..We therefore conclude that measuring endotoxin levels with the EDC is a valid measure of average airborne endotoxin exposure, while reproducibility over time is at least equivalent to that of reservoir dust analyses...
  71. ncbi Stakeholder needs for air pollution and health information
    Eric Gordon Sanderson
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    J Toxicol Environ Health A 69:1819-25. 2006
    ....
  72. ncbi Validity of residential traffic intensity as an estimate of long-term personal exposure to traffic-related air pollution among adults
    Sofie van Roosbroeck
    Division Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, P O Box 801 78, 3508 TD Utrecht, The Netherlands
    Environ Sci Technol 42:1337-44. 2008
    ..Time spent in traffic and spending time outdoors were associated with increased personal exposure of soot and PM2.5, but not NOx...
  73. doi Asthma and allergic symptoms in relation to house dust endotoxin: Phase Two of the International Study on Asthma and Allergies in Childhood (ISAAC II)
    U Gehring
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Clin Exp Allergy 38:1911-20. 2008
    ..Several studies have consistently reported inverse associations between exposure to endotoxin in house dust and atopy. With regard to the association between house dust endotoxin and asthma, the results are inconsistent...
  74. ncbi Bacterial and fungal components in house dust of farm children, Rudolf Steiner school children and reference children--the PARSIFAL Study
    D Schram
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Allergy 60:611-8. 2005
    ..It has been suggested that the enhanced exposure to endotoxin is an important protective factor of farm environments. Little is known about exposure to other microbial components on farms and exposure in anthroposophic families...
  75. pmc In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential--the RAPTES project
    Maaike Steenhof
    Division of Toxicology, Institute for Risk Assessment Sciences, Utrecht University, PO Box 80177, 3508 TD Utrecht, The Netherlands
    Part Fibre Toxicol 8:26. 2011
    ..This study investigated the in vitro toxicity of ambient PM collected at different sites in the Netherlands in relation to PM composition and oxidative potential...
  76. doi Polymorphisms in the mannan-binding lectin gene are not associated with questionnaire-reported respiratory tract infections in children
    Jopje M Ruskamp
    Department of Pediatrics, Wilhelmina Children s Hospital, University Medical Center Utrecht, University of Utrecht, Lundlaan 6, Utrecht, The Netherlands
    J Infect Dis 198:1707-13. 2008
    ..Large-scale replication of previous associations is needed, however. We investigated the association between MBL2 polymorphisms and the frequency of RTI in a large population-based birth cohort of white children...
  77. ncbi The impact of ambient NO on online measurements of exhaled and nasal NO: the PIAMA study
    Ulrike Gehring
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Pediatr Allergy Immunol 20:665-72. 2009
    ..The currently recommended technique including inhalation through an NO scrubber effectively deals with variable levels of ambient NO on FENO. In contrast, ambient NO has an effect on measurements of nNO...
  78. ncbi Neonatal total IgE and respiratory tract infections in children with intrauterine smoke exposure
    Jopje Ruskamp
    Department of Paediatrics, Wilhelmina Children s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
    Arch Dis Child 95:427-31. 2010
    ..We examined whether early atopic status (defined by elevated neonatal total IgE (tIgE) or symptoms of atopic dermatitis) modified the association between ETS exposure and RTI...
  79. ncbi Determinants of house dust endotoxin in three European countries - the AIRALLERG study
    M Giovannangelo
    Utrecht University, Institute for Risk Assessment Sciences, Utrecht, The Netherlands
    Indoor Air 17:70-9. 2007
    ..The variability of the endotoxin levels between homes and countries can only be partly explained by these factors...
  80. ncbi Repeated measurements of mite and pet allergen levels in house dust over a time period of 8 years
    C J M Antens
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Clin Exp Allergy 36:1525-31. 2006
    ..Studies of the association between indoor allergen exposure and the development of allergic diseases have often measured allergen exposure at one point in time...
  81. doi The joint association of air pollution and noise from road traffic with cardiovascular mortality in a cohort study
    R Beelen
    Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, PO Box 80178, 3508 TD Utrecht, The Netherlands
    Occup Environ Med 66:243-50. 2009
    ..Associations between cardiovascular mortality and air pollution and noise together were investigated...
  82. ncbi The Wheezing Illnesses Study Leidsche Rijn (WHISTLER): rationale and design
    N Katier
    Department of Pediatric Pulmonology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Eur J Epidemiol 19:895-903. 2004
    ..In the scope of prevention, WHISTLER is expected to support the design of solid based prevention measures to reduce respiratory morbidity, mortality and associated costs, and to improve quality of life...
  83. ncbi Nonlinear relations between house dust mite allergen levels and mite sensitization in farm and nonfarm children
    D Schram-Bijkerk
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    Allergy 61:640-7. 2006
    ..It is not known how microbial agents modify the association between specific allergen exposure and sensitization...
  84. doi Inverse association between endotoxin exposure and canine atopic dermatitis
    Frank A Looringh van Beeck
    Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands
    Vet J 190:215-9. 2011
    ..The results indicated that endotoxin exposure is inversely associated with CAD, suggesting a protective effect of high indoor endotoxin exposure towards the development of the condition...
  85. pmc Use of passive diffusion sampling method for defining NO2 concentrations gradient in São Paulo, Brazil
    Agnes Soares da Silva
    Institute for Risk Assessment Sciences IRAS, Utrecht University, Yalelaan 2, 3508 TD, Utrecht, The Netherlands
    Environ Health 5:19. 2006
    ..This study was intended to identify a gradient of exposure to traffic-related air pollution within different areas in São Paulo to provide information for future epidemiological studies...
  86. ncbi Reported versus measured body weight and height of 4-year-old children and the prevalence of overweight
    Salome Scholtens
    Institute for Risk Assessment Sciences IRAS, Utrecht University, Utrecht, The Netherlands
    Eur J Public Health 17:369-74. 2007
    ..In addition, we studied the determinants and the consequences of differences between reported and measured data...
  87. ncbi A critique of "fine particulate air pollution and total mortality among elderly Californians, 1973-2002" by James E. Enstrom
    Bert Brunekreef
    Institute for Risk Assessment Sciences, Universiteit Utrecht, Utrecht, The Netherlands
    Inhal Toxicol 18:507-8; discussuin 509-14. 2006
  88. ncbi Early, current and past pet ownership: associations with sensitization, bronchial responsiveness and allergic symptoms in school children
    G Anyo
    Institute for Risk Assessment Sciences, Division of Environmental and Occupational Health, Utrecht University, Utrecht, The Netherlands
    Clin Exp Allergy 32:361-6. 2002
    ..Studies have suggested that early contact with pets may prevent the development of allergy and asthma...
  89. pmc Associations between PM2.5 and heart rate variability are modified by particle composition and beta-blocker use in patients with coronary heart disease
    Jeroen J de Hartog
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Environ Health Perspect 117:105-11. 2009
    ..Previously we reported heterogeneous associations between particulate matter with aerodynamic diameter < 2.5 microm (PM2.5) and HRV across three study centers...
  90. doi Concentration response functions for ultrafine particles and all-cause mortality and hospital admissions: results of a European expert panel elicitation
    Gerard Hoek
    Institute for Risk Assessment Sciences and Copernicus Institute, University of Utrecht, Utrecht, The Netherlands
    Environ Sci Technol 44:476-82. 2010
    ..This expert elicitation provides the first quantitative evaluation of estimates of concentration response functions between urban air ultrafine particles and all-cause mortality and hospital admissions...
  91. ncbi Association between mortality and indicators of traffic-related air pollution in the Netherlands: a cohort study
    Gerard Hoek
    Institute for Risk Assessment Sciences, Environmental and Occupational Health Group, Utrecht University, Utrecht, Netherlands
    Lancet 360:1203-9. 2002
    ..We aimed to assess the relation between traffic-related air pollution and mortality in participants of the Netherlands Cohort study on Diet and Cancer (NLCS), an ongoing study...
  92. ncbi Design of cohort studies for air pollution health effects
    Bert Brunekreef
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands
    J Toxicol Environ Health A 66:1723-9. 2003
    ..In addition, following the examples of Sweden, the Netherlands, and Germany, the use of geographical information systems is recommended to assess exposure to air pollutants at the address rather than the community level...
  93. ncbi Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study
    D Schram-Bijkerk
    Institute for Risk Assessment Sciences, University of Utrecht, Utrecht, The Netherlands, and Children s Hospital, Salzburg, Austria
    Clin Exp Allergy 35:1272-8. 2005
    ..Growing up on a farm and an anthroposophic lifestyle are associated with a lower prevalence of allergic diseases in childhood. This might be related to increased inhalatory exposure to microbial agents...
  94. ncbi Bronchial hyper-responsiveness to hypertonic saline and blood eosinophilic markers in 8-13-year-old schoolchildren
    G de Meer
    Institute for Risk Assessment Sciences, Environmental and Occupational Health, Utrecht University, The Netherlands
    Clin Exp Allergy 34:1226-31. 2004
    ..In adult asthma, bronchial hyper-responsiveness (BHR) to indirect stimuli reflects eosinophilic activation more closely than BHR to stimuli that directly cause smooth muscle contraction...
  95. ncbi Breast feeding, parental allergy and asthma in children followed for 8 years. The PIAMA birth cohort study
    S Scholtens
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Thorax 64:604-9. 2009
    ..These factors--the age of the child and maternal or paternal allergy--might partly explain the conflicting results observed in cross-sectional studies...
  96. pmc Comparison of parental reports of smoking and residential air nicotine concentrations in children
    U Gehring
    Utrecht University, Institute for Risk Assessment Sciences, Utrecht, The Netherlands
    Occup Environ Med 63:766-72. 2006
    ..Questionnaire data have frequently been validated against urinary cotinine measurements, but rarely against actual measurements of residential air nicotine...
  97. ncbi Exhaled nitric oxide predicts airway hyper-responsiveness to hypertonic saline in children that wheeze
    G de Meer
    Institute for Risk Assessment Sciences, Environmental and Occupational Health Unit, Utrecht University, Utrecht
    Allergy 60:1499-504. 2005
    ..In large-scale epidemiological studies, this method would be preferred above airway challenge tests, because it is a quick and easy applicable tool...
  98. pmc Personal and outdoor nitrogen dioxide concentrations in relation to degree of urbanization and traffic density
    E Rijnders
    Institute for Risk Assessment Sciences, Environmental and Occupational Health Group, Utrecht University, 3508 TD Utrecht, Netherlands
    Environ Health Perspect 109:411-7. 2001
    ....
  99. pmc Repeatability of bronchial hyperresponsiveness to adenosine-5'-monophosphate (AMP) by a short dosimeter protocol
    G de Meer
    Institute for Risk Assessment Sciences, Division of Environmental and Occupational Health, University of Utrecht, P O Box 20176, 3508 TD Utrecht, Netherlands
    Thorax 56:362-5. 2001
    ..To study bronchial responsiveness to adenosine 5'-monophosphate (AMP) in population surveys, repeatability of a rapid dosimetric method with quadrupling doses was evaluated...
  100. ncbi Estimation of long-term average exposure to outdoor air pollution for a cohort study on mortality
    G Hoek
    Environmental and Occupational Health Group, Utrecht University, Wageningen, The Netherlands
    J Expo Anal Environ Epidemiol 11:459-69. 2001
    ..About 90% of the study population lived 10 years or more at its 1986 home address - supporting the use of the estimated concentration at the 1986 address as a relevant exposure variable...
  101. ncbi Airway responsiveness to hypertonic saline: dose-response slope or PD15?
    G de Meer
    Institute for Risk Assessment Sciences, Environmental and Occupational Health, Utrecht University, P Box 80176, 3508 TD Utrecht, The Netherlands
    Eur Respir J 25:153-8. 2005
    ..In conclusion, the continuous relationship between airway responsiveness and asthma symptoms is in favour of a noncensored measure of airway responsiveness, such as the dose-response slope...