B J Blaauboer

Summary

Affiliation: Institute for Risk Assessment Sciences
Country: The Netherlands

Publications

  1. pmc The need for a new toxicity testing and risk analysis paradigm to implement REACH or any other large scale testing initiative
    Bas J Blaauboer
    Arch Toxicol 81:385-7. 2007
  2. ncbi The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary
    B J Blaauboer
    Institute for Risk Assessment Sciences, Division of Toxicology, Utrecht University, P O Box 80 176, 3508 TD Utrecht, The Netherlands
    Toxicol Lett 138:161-71. 2003
  3. pmc 13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies and conceptual issues
    B J Blaauboer
    RITOX, Utrecht University, The Netherlands
    Environ Health Perspect 106:413-8. 1998
  4. doi In vitro neuroendocrine effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the AhR-expressing hypothalamic rat GnV-3 cell line
    K A Solak
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Toxicology 311:124-34. 2013
  5. ncbi An alternative approach for the safety evaluation of new and existing chemicals, an exercise in integrated testing
    W M L G Gubbels-van Hal
    NOTOX B V, 5203 DL s Hertogenbosch, The Netherlands
    Regul Toxicol Pharmacol 42:284-95. 2005
  6. ncbi Methods of in vitro toxicology
    G Eisenbrand
    University of Kaiserslautern, Department of Chemistry Food Chemistry and Environmental Toxicology, PO Box 3049, D 67653, Kaiserslautern, Germany
    Food Chem Toxicol 40:193-236. 2002

Collaborators

Detail Information

Publications6

  1. pmc The need for a new toxicity testing and risk analysis paradigm to implement REACH or any other large scale testing initiative
    Bas J Blaauboer
    Arch Toxicol 81:385-7. 2007
  2. ncbi The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary
    B J Blaauboer
    Institute for Risk Assessment Sciences, Division of Toxicology, Utrecht University, P O Box 80 176, 3508 TD Utrecht, The Netherlands
    Toxicol Lett 138:161-71. 2003
    ..Their implementation will allow a much more scientifically-based and a better structured risk assessment, which will be to a much lesser extent relying on animal experimentation...
  3. pmc 13th meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies and conceptual issues
    B J Blaauboer
    RITOX, Utrecht University, The Netherlands
    Environ Health Perspect 106:413-8. 1998
    ....
  4. doi In vitro neuroendocrine effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the AhR-expressing hypothalamic rat GnV-3 cell line
    K A Solak
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Toxicology 311:124-34. 2013
    ..Overall, the combined results demonstrate that GnV-3 cells may be a suitable model to predict some mechanisms of action and effects of AhR ligands in the hypothalamus. ..
  5. ncbi An alternative approach for the safety evaluation of new and existing chemicals, an exercise in integrated testing
    W M L G Gubbels-van Hal
    NOTOX B V, 5203 DL s Hertogenbosch, The Netherlands
    Regul Toxicol Pharmacol 42:284-95. 2005
    ..This integrated approach leads to a 38% reduction of laboratory animals...
  6. ncbi Methods of in vitro toxicology
    G Eisenbrand
    University of Kaiserslautern, Department of Chemistry Food Chemistry and Environmental Toxicology, PO Box 3049, D 67653, Kaiserslautern, Germany
    Food Chem Toxicol 40:193-236. 2002
    ..Major weaknesses and strengths of these assay systems are addressed, together with some key issues concerning major research priorities to improve hazard identification and characterisation of food-associated chemicals...