Research Topics
| Peter E SpronkSummaryAffiliation: Gelre Hospitals Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
Decisional responsibility for mechanical ventilation and weaning: an international surveyLouise Rose
Lawrence S, Bloomberg Faculty of Nursing, University of Toronto, 155 College St, Toronto, M5T 1P8, Canada
Crit Care 15:R295. 2011..Our objective was to describe the professional group with responsibility for key ventilation and weaning decisions and to examine organizational characteristics associated with nurse involvement...- Mild hypoglycemia is independently associated with increased mortality in the critically illJames S Krinsley
Division of Critical Care, Stamford Hospital, Columbia University College of Physicians and Surgeons, 190 West Broad Street, Stamford, CT 06902, USA
Crit Care 15:R173. 2011..The association of milder hypoglycemia (BG < 70 mg/dL) with mortality is less clear... - No agreement of mixed venous and central venous saturation in sepsis, independent of sepsis originPaul A van Beest
Department of Anesthesiology, University Medical Center Groningen, Hanzeplein 1, Groningen, 9700 RB, The Netherlands
Crit Care 14:R219. 2010..We tested the hypothesis that ScvO(2) does not reliably predict SvO(2) in sepsis. Additionally we looked at the influence of the source (splanchnic or non-splanchnic) of sepsis on this relationship... - Tight glycaemic control: intelligent technology or a nurse-wise strategy?Mart J de Graaff
Crit Care 11:421. 2007 - Off hour admission to an intensivist-led ICU is not associated with increased mortalityIwan A Meynaar
ICU, Reinier de Graaf Groep, Reinier de Graafweg 3 11, 2625 AD Delft, Netherlands
Crit Care 13:R84. 2009..Caring for the critically ill is a 24-hour-a-day responsibility, but not all resources and staff are available during off hours. We evaluated whether intensive care unit (ICU) admission during off hours affects hospital mortality... - The incidence of low venous oxygen saturation on admission to the intensive care unit: a multi-center observational study in The NetherlandsPaul A van Beest
Medical Center Leeuwarden, Leeuwarden, The Netherlands
Crit Care 12:R33. 2008..Early goal directed therapy (EGDT), aiming at an ScvO2 >/= 70%, has been shown to be a valuable strategy in patients with sepsis or septic shock and is incorporated in the Surviving Sepsis Campaign guidelines... - Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation studyE Christiaan Boerma
Department of Physiology, Academic Medical Centre, University of Amsterdam, The Netherlands
Crit Care 9:R601-6. 2005..Essential to the process of understanding and reproducing these abnormalities is the method of quantification of flow scores... 
The practice of and documentation on withholding and withdrawing life support: a retrospective study in two Dutch intensive care unitsPeter E Spronk
Department of Intensive Care Medicine, Gelre Hospitals, Location Lukas, Apeldoorn, The Netherlands
Anesth Analg 109:841-6. 2009..We determined how often life support was withheld or withdrawn in patients who died in the intensive care unit (ICU) or early after ICU discharge and evaluated documentation on decisions regarding these changes in life support orders...- Brachio-cephalic ('Gracz') fistula use for continuous hemofiltration in a hemodynamically unstable hemodialysis patient without venous vascular access: a case reportPeter E Spronk
Department of Intensive Care Medicine, Gelre Hospitals, Apeldoorn, The Netherlands
J Med Case Reports 1:39. 2007..We describe a technique of using a brachio-cephalic arterio-venous fistula in a hemodialysis patient for continuous hemofiltration (HF) resulting in improved hemodynamic stability... - Bench-to-bedside review: sepsis is a disease of the microcirculationPeter E Spronk
Department of Intensive Care Medicine, Gelre Ziekenhuizen, Apeldoorn, The Netherlands
Crit Care 8:462-8. 2004.... 
Thrombolysis in fulminant purpura: observations on changes in microcirculatory perfusion during successful treatmentPeter E Spronk
Department of Intensive Care Medicine, Gelre Hospitals, Lukas site, Alpeldoorn, The Netherlands
Thromb Haemost 95:576-8. 2006- Occurrence of delirium is severely underestimated in the ICU during daily carePeter E Spronk
Department of Intensive Care Medicine, Gelre Hospitals, Location Lukas, Albert Schweitzerlaan 31, 7334 DZ, Apeldoorn, The Netherlands
Intensive Care Med 35:1276-80. 2009..Therefore, the recognition of delirium is important. We investigated whether intensivists and ICU nurses could clinically identify the presence of delirium in ICU patients during daily care... - Cardiac tamponade, an unusual and fatal complication of esophagus dilatation for benign stenosis: a case reportWendela L Greven
Department of Intensive Care, Gelre Hospitals, Lukas site, Post office Box 9014, 7300 DS, Apeldoorn, The Netherlands
Cases J 1:419. 2008..We present a patient with a fatal late esophago-pericardial fistula three months after dilatation for benign oesophagus stenosis.. - Re: Regional citrate anticoagulation does not prolong filter survival during CVVHPeter E Spronk
Department of Intensive Care Medicine, Gelre Hospitals, Apeldoorn, and Academic Medical Center, Amsterdam, The Netherlands
J Crit Care 21:291-2; author reply 290-1. 2006 - Changes of health-related quality of life in critically ill octogenarians: a follow-up studyJose G M Hofhuis
Department of Intensive Care, Gelre Hospital, Apeldoorn, The Netherlands
Chest 140:1473-83. 2011..Intensivists frequently are concerned about whether octogenarians actually will benefit from ICU admission. We studied changes in health-related quality of life (HRQOL) 6 months following ICU discharge in those patients... - Reliability of height and weight estimates in patients acutely admitted to intensive care unitsRogier M Determann
Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
Crit Care Nurse 27:48-55; quiz 56. 2007 - Experiences of critically ill patients in the ICUJose G M Hofhuis
Department of Intensive Care Medicine, Gelre Hospital, Lukas, Apeldoorn, The Netherlands
Intensive Crit Care Nurs 24:300-13. 2008..Experiences of critically ill patients are an important aspect of the quality of care in the intensive care (ICU)... - Limitations and practicalities of CAM-ICU implementation, a delirium scoring system, in a Dutch intensive care unitBea Riekerk
Department of Intensive Care Medicine, Gelre Hospital, LUCAS, The Netherlands
Intensive Crit Care Nurs 25:242-9. 2009..This report focusses on the obstacles and barriers encountered with respect to organisational context and prevailing opinions and attitudes when implementing the CAM-ICU in daily practice in a Dutch ICU... - On-demand rather than daily-routine chest radiography prescription may change neither the number nor the impact of chest computed tomography and ultrasound studies in a multidisciplinary intensive care unitAnke Kröner
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Anesthesiology 108:40-5. 2008..Elimination of daily-routine chest radiographs (CXRs) may influence chest computed tomography (CT) and ultrasound practice in critically ill patients... - Management of tracheostomy: a survey of Dutch intensive care unitsDenise P Veelo
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Respir Care 53:1709-15. 2008..To determine tracheostomy-management practices in Dutch intensive care units (ICUs) and post-ICU step-down facilities... - Low value of routine chest radiographs in a mixed medical-surgical ICUKarin A Hendrikse
Department of Radiology, Gelre Hospitals, Lukas site, Albert Schweitzerlaan 31, 7334 DZ Apeldoorn, The Netherlands
Chest 132:823-8. 2007.... - Conceptual issues specifically related to health-related quality of life in critically ill patientsJose G M Hofhuis
Department of Intensive Care, Gelre Hospitals Location Lukas, Apeldoorn, The Netherlands
Crit Care 13:118. 2009..Furthermore, vigilance for symptoms of PTSD and early interventions to prevent PTSD are needed... - The impact of severe sepsis on health-related quality of life: a long-term follow-up studyJose G M Hofhuis
Department of Intensive Care, Gelre Hospital, Location Lukas, Apeldoorn, The Netherlands
Anesth Analg 107:1957-64. 2008..The time course of changes in HRQOL in severe sepsis survivors after discharge from the intensive care unit (ICU) and during a general ward stay have not been studied... - Implementing glucose control in intensive care: a multicenter trial using statistical process controlSaeid Eslami
Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
Intensive Care Med 36:1556-65. 2010..In this study we investigated GC performance over time during implementation of GC strategies within three intensive care units (ICUs) and in routine clinical practice... - Elimination of daily routine chest radiographs in a mixed medical-surgical intensive care unitMarleen E Graat
Department of Intensive Care Medicine, Academic Medical Center, Mail stop C3 329, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Intensive Care Med 33:639-44. 2007..To determine the impact of elimination of daily routine chest radiographs (CXRs) in a mixed medical-surgical intensive care unit (ICU) on utility of on demand CXRs, length of stay (LOS) in ICU, readmission rate, and mortality rate... - Health-related quality of life in critically ill patients: how to score and what is the clinical impact?Jose G M Hofhuis
Department of Intensive Care, Gelre Hospital Location Lukas, Apeldoorn, The Netherlands
Curr Opin Crit Care 15:425-30. 2009..Health-related quality of life (HRQOL) is an important issue for both patients and family. The purpose of this review is to describe HRQOL scoring in critically ill patients and to discuss the clinical impact on HRQOL... - Sleep disturbances and sedation practices in the intensive care unit--a postal survey in the NetherlandsJose G M Hofhuis
Department of Intensive Care Gelre Hospitals, Apeldoorn, The Netherlands
Intensive Crit Care Nurs 28:141-9. 2012..Sleep disturbances are common in critically ill patients treated in the intensive care unit (ICU) with possible serious consequences... - Elimination of daily routine chest radiographs does not change on-demand radiography practice in post-cardiothoracic surgery patientsOnno Mets
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Thorac Cardiovasc Surg 134:139-44. 2007..We sought to determine the effect of elimination of daily routine chest radiographs on chest radiographic practice in cardiothoracic surgery patients in the intensive care unit and the post-intensive care unit ward... - Mechanical ventilation with lower tidal volumes does not influence the prescription of opioids or sedativesEsther K Wolthuis
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Crit Care 11:R77. 2007.... - The incidence and microbial spectrum of ventilator-associated pneumonia after tracheotomy in a selective decontamination of the digestive tract-settingDenise P Veelo
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Infect 56:20-6. 2008..Selective decontamination of the digestive tract (SDD) aims to prevent VAP in critically ill patients, including those after tracheotomy. We determined the incidence and microbial spectrum of VAP after tracheotomy in a SDD-setting... - The Academic Medical Center Linear Disability Score for evaluation of physical reserve on admission to the ICU: can we query the relatives?Jose G M Hofhuis
Department of Intensive Care, Gelre Hospital, Apeldoorn, Albert Schweitzerlaan 31, 7334 DZ Apeldoorn, The Netherlands
Crit Care 15:R212. 2011..We aimed to study whether proxy scoring with the ALDS could be used to assess the patients' functional status on admission for cardiac care unit (CCU) or ICU patients and how the ALDS relates to the PCS using the Short Form 12 (SF-12)... - Lung-protective mechanical ventilation does not protect against acute kidney injury in patients without lung injury at onset of mechanical ventilationBart Cortjens
Laboratory of Experimental Intensive Care and Anesthesiology LEICA, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Crit Care 27:261-7. 2012..Preclinical and clinical studies suggest that mechanical ventilation contributes to the development of acute kidney injury (AKI), particularly in the setting of lung-injurious ventilator strategies... - Treatment of hypophosphatemia in the intensive care unit: a reviewDaniël A Geerse
Department of Intensive Care Medicine, Catharina Hospital Eindhoven, Michelangelolaan 2, Eindhoven 5623 EJ, The Netherlands
Crit Care 14:R147. 2010..Currently no evidence-based guideline exists for the approach to hypophosphatemia in critically ill patients... - Clinical review: Strict or loose glycemic control in critically ill patients--implementing best available evidence from randomized controlled trialsMarcus J Schultz
Department of Intensive Care, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Crit Care 14:223. 2010.... - Nitroglycerin in septic shock after intravascular volume resuscitationPeter E Spronk
Department of Intensive Care Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands
Lancet 360:1395-6. 2002..The infusion of 0.5 mg of nitroglycerin intravenously then resulted in a marked increase in microvascular flow on OPS imaging. Improved recruitment of the microcirculation could be a new resuscitation endpoint in septic shock... - Survey into bereavement of family members of patients who died in the intensive care unitMarjoleine A van der Klink
Department of Intensive Care, Gelre Hospitals, Apeldoorn, The Netherlands
Intensive Crit Care Nurs 26:215-25. 2010..The death of a family member in the intensive care unit (ICU) is often sudden and unexpected and may have a strong impact on family members... - Systemic and urinary neutrophil gelatinase-associated lipocalins are poor predictors of acute kidney injury in unselected critically ill patientsAnnick A Royakkers
Department of Intensive Care Medicine, Tergooi Hospitals, location Blaricum, 1261 AN Blaricum, The Netherlands Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Crit Care Res Pract 2012:712695. 2012..AUC of sNGAL and uNGAL for the prediction of renal replacement therapy requirement was 0.47 (CI 0.37-0.58) and 0.26 (CI 0.03-0.50). Conclusions. In unselected critically ill patients, sNGAL and uNGAL are poor predictors of AKI or RRT... - The clinical value of daily routine chest radiographs in a mixed medical-surgical intensive care unit is lowMarleen E Graat
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Crit Care 10:R11. 2006..CONCLUSION: In the ICU, daily routine CXRs seldom reveal unexpected, clinically relevant abnormalities, and they rarely prompt action. We propose that this diagnostic examination be abandoned in ICU patients... - Hospital mortality is associated with ICU admission timeHans A J M Kuijsten
Department of Intensive Care Medicine, University Medical Center Utrecht, Location AZU, Room F06 135, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Intensive Care Med 36:1765-71. 2010..However these results have been challenged by numerous other studies. We therefore analysed this possible relationship between ICU admission time and in-hospital mortality in The Netherlands... - Routine use of the confusion assessment method for the intensive care unit: a multicenter studyMaarten M van Eijk
Department of Intensive Care Medicine, University Medical Center Utrecht, The Netherlands
Am J Respir Crit Care Med 184:340-4. 2011..The Confusion Assessment Method for the ICU (CAM-ICU) has high sensitivity and specificity for delirium when administered by research nurses. However, test characteristics of the CAM-ICU as performed in routine practice are unclear... - Changes in the volume status of haemodialysis patients are reflected in sublingual microvascular perfusionRemy H H Bemelmans
1Department of Intensive Care Medicine, Gelre Ziekenhuizen, Lukas site, Apeldoorn, The Netherlands
Nephrol Dial Transplant 24:3487-92. 2009..Secondly, we evaluated microcirculatory response to autotransfusion using the Trendelenburg position (TP)... - A change in the Dutch Directive on Medical Research Involving Human Subjects strongly increases the number of eligible intensive care patients: an observational studyDenise P Veelo
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Intensive Care Med 32:1845-50. 2006..Representatives felt very confident in their ability to represent the patients. In turn patients were equally confident that their representatives were able to represent them... - Year in review 2006: Critical Care--Resource managementMarcus J Schultz
Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Crit Care 11:223. 2007..Finally, several aspects of scientific research in critically ill patients were investigated, focusing on the possibility of obtaining informed consent and recall of having given informed consent... - Quality of life before intensive care unit admission is a predictor of survivalJose G M Hofhuis
Department of Intensive Care Medicine, Gelre Hospitals Location Lukas, Albert Schweitzerlaan, 7334 DZ Apeldoorn, The Netherlands
Crit Care 11:R78. 2007..The purpose of the present study was to examine whether health-related quality of life (HRQOL) before admission to the ICU can be used as a predictor of mortality... - Serum cystatin C-A useful endogenous marker of renal function in intensive care unit patients at risk for or with acute renal failure?Annick A N M Royakkers
Department of Intensive Care, Tergooi Hospitals, location Blaricum, Rijksstraatweg 1, 1261 AN Blaricum, The Netherlands
Curr Med Chem 14:2314-7. 2007..Cystatin C could be an important tool both to recognize early renal dysfunction and to identify renal recovery while on CRRT in the critically ill patient, however, we are in need of more studies... - Accumulation of advanced glycation end (AGEs) products in intensive care patients: an observational, prospective studyWendela L Greven
Department of Intensive Care Medicine, Gelre Hospitals, Location Lukas, Apeldoorn, The Netherlands
BMC Clin Pathol 10:4. 2010..Since AGEs have emerged to be stable end products, these can be a marker of oxidative stress. Skin autofluorescence (AF) is a validated marker of tissue content of AGEs. We hypothesized that AGEs accumulate acutely in ICU patients... - Septic thrombosis of the inferior vena cava treated with percutaneous mechanical thrombectomyMark C Burgmans
Department of Radiology, Gelre Hospitals, site Lukas, Albert Schweitzerlaan 31, 7334 DZ Apeldoorn, The Netherlands
J Vasc Interv Radiol 17:1697-702. 2006..Percutaneous mechanical thrombectomy was performed, resulting in removal of the infected thrombus and complete clinical recovery... - Practice of strict glycemic control in critically ill patientsMarcus J Schultz
Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Med Sci Monit 14:RA191-7. 2008..For several reasons it is wise to have strict glycemic control being a nurse-based strategy... - Encephalopathy and MRI abnormalities in fat embolism syndrome: a case reportChristianne J Buskens
Department of Surgery, Gelre Ziekenhuizen, Apeldoorn, The Netherlands
Med Sci Monit 14:CS125-9. 2008..Fat embolism syndrome can be a life-threatening condition, but the latent form that occurs 24 to 72 hours after the trauma is frequently described as a self-limiting condition... - Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsisE Christiaan Boerma
Department of Physiology, Academic Medical Center, University of Amsterdam, The Netherlands
Crit Care Med 35:1055-60. 2007..To evaluate the relation between sublingual and intestinal microcirculatory alterations in patients with abdominal sepsis... - The impact of critical illness on perceived health-related quality of life during ICU treatment, hospital stay, and after hospital discharge: a long-term follow-up studyJose G M Hofhuis
Erasmus MC University Medical Center Rotterdam, Department of ICU, PO Box 2040, Room HS320, 3000 CA Rotterdam, The Netherlands
Chest 133:377-85. 2008..We therefore studied the immediate impact of critical illness on HRQOL and its recovery over time... - Need for critical appraisal of implementation of use of lower tidal volumesMarcus J Schultz
Crit Care Med 33:2718; author reply 2718-9. 2005 - Does red blood cell transfusion result in a variate microvascular response in sepsis?Corstiaan A den Uil
Crit Care Med 35:2464-5; author reply 2465. 2007 - Norepinephrine compromises intestinal microvascular perfusion?Peter E Spronk
Intensive Care Med 30:173-4; author reply 175. 2004 - Intensive insulin therapy in intensive care: an example of the struggle to implement evidence-based medicineMarcus J Schultz
Department of Intensive Care Medicine and the Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
PLoS Med 3:e456. 2006 - Glucose levels of critically ill patients to calculate the hyperglycemic indexMarcus J Schultz
J Trauma 61:476-7; author reply 477. 2006 - Impaired sublingual microvascular perfusion during surgery with cardiopulmonary bypass: a pilot studyCorstiaan A den Uil
Erasmus MC Thoraxcenter, Rotterdam, The Netherlands
J Thorac Cardiovasc Surg 136:129-34. 2008..Microcirculatory blood flow alterations have been associated with impaired outcome. We investigated whether these alterations occurred before, during, and after coronary artery bypass grafting... - Monitoring of the sublingual microcirculation in cardiac surgery using two-dimensional imagingCorstiaan A den Uil
Anesthesiology 109:353-4; author reply 354-5. 2008 - Two cohorts of severely injured trauma patients, nearly two decades apartJose G M Hofhuis
J Trauma 65:495-6. 2008 - The new Surviving Sepsis Campaign recommendations on glucose control should be reconsideredMarcus J Schultz
Intensive Care Med 34:779-80; author reply 781-2. 2008 - Dobutamine to rescue the microcirculation?Peter E Spronk
Crit Care Med 34:2700; author reply 2700-1. 2006 - Tight glycaemic control: a survey of intensive care practice in the NetherlandsMarcus J Schultz
Intensive Care Med 32:618-9; author reply 620-1. 2006 - Timing of tracheostomy in adult patients: conclusions may be prematureMarcus J Schultz
BMJ 331:404; author reply 404-5. 2005 - Draining all pleural effusions in the intensive care unit?Peter E Spronk
Crit Care Med 34:269; author reply 269-70. 2006 - Overweight in ICU patients: is the body mass index reliable?Marcus J Schultz
Chest 127:683-4; author reply 684. 2005