Ruben H Willemsen

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi Effect of growth hormone therapy on serum adiponectin and resistin levels in short, small-for-gestational-age children and associations with cardiovascular risk parameters
    Ruben H Willemsen
    Department of Pediatrics, Erasmus Medical Center Sophia, Room SP 3435, Dr Molenwaterplein 60, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 92:117-23. 2007
  2. ncbi Long-term effects of growth hormone (GH) treatment on body composition and bone mineral density in short children born small-for-gestational-age: six-year follow-up of a randomized controlled GH trial
    Ruben H Willemsen
    Department of Pediatrics, Division of Endocrinology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 67:485-92. 2007
  3. ncbi Long-term GH treatment is not associated with disadvantageous changes of inflammatory markers and adipocytokines in children born small for gestational age
    Ruben H Willemsen
    Department of Pediatrics, Division of Endocrinology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 68:198-205. 2008
  4. ncbi Independent effects of prematurity on metabolic and cardiovascular risk factors in short small-for-gestational-age children
    Ruben H Willemsen
    Department of Paediatrics, Division of Endocrinology, Erasmus MC Sophia, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 93:452-8. 2008
  5. doi Plasma matrix metalloproteinase-9 levels and blood pressure in short children born small for gestational age and effects of growth hormone treatment
    Ruben H Willemsen
    Department of Paediatrics, Division of Endocrinology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 69:264-8. 2008
  6. doi Prematurity is not associated with reduced insulin sensitivity in adulthood
    Ruben H Willemsen
    Department of Pediatrics, Division of Endocrinology, Erasmus Medical Centre Sophia, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 94:1695-700. 2009
  7. doi Longitudinal changes in insulin sensitivity and body composition of small-for-gestational-age adolescents after cessation of growth hormone treatment
    Ruben H Willemsen
    Department of Pediatrics, Division of Endocrinology, Erasmus Medical Center Sophia, GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 93:3449-54. 2008
  8. doi Does preterm birth influence the response to growth hormone treatment in short, small for gestational age children?
    Sandra W K de Kort
    Department of Paediatrics, Division of Endocrinology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 70:582-7. 2009
  9. doi Cardiovascular risk factors in parents of short children born small for gestational age
    Sandra W K de Kort
    Department of Pediatrics, Erasmus MC Sophia, Rotterdam, 3015 GJ, The Netherlands
    Pediatr Res 64:91-6. 2008
  10. doi Does preterm birth influence cardiovascular risk in early adulthood?
    Gerthe F Kerkhof
    Department of Pediatrics, Subdivision of Endocrinology, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    J Pediatr 161:390-396.e1. 2012

Collaborators

Detail Information

Publications15

  1. ncbi Effect of growth hormone therapy on serum adiponectin and resistin levels in short, small-for-gestational-age children and associations with cardiovascular risk parameters
    Ruben H Willemsen
    Department of Pediatrics, Erasmus Medical Center Sophia, Room SP 3435, Dr Molenwaterplein 60, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 92:117-23. 2007
    ..In short, small-for-gestational-age (SGA) children, GH therapy has several positive effects regarding cardiovascular risk factors. On the other hand, concern has been expressed about the effects of GH therapy on insulin sensitivity...
  2. ncbi Long-term effects of growth hormone (GH) treatment on body composition and bone mineral density in short children born small-for-gestational-age: six-year follow-up of a randomized controlled GH trial
    Ruben H Willemsen
    Department of Pediatrics, Division of Endocrinology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 67:485-92. 2007
    ..In addition, birth weight has been inversely associated with diabetes and cardiovascular disease in adult life. Data on detailed body composition in short SGA children and long-term effects of GH treatment are very scarce...
  3. ncbi Long-term GH treatment is not associated with disadvantageous changes of inflammatory markers and adipocytokines in children born small for gestational age
    Ruben H Willemsen
    Department of Pediatrics, Division of Endocrinology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 68:198-205. 2008
    ..No data exist on the effect of long-term GH treatment on these hormones and inflammatory markers in children born small for gestational age (SGA)...
  4. ncbi Independent effects of prematurity on metabolic and cardiovascular risk factors in short small-for-gestational-age children
    Ruben H Willemsen
    Department of Paediatrics, Division of Endocrinology, Erasmus MC Sophia, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 93:452-8. 2008
    ..However, it is unclear whether preterm birth has an additional effect on cardiovascular risk factors in short children born SGA...
  5. doi Plasma matrix metalloproteinase-9 levels and blood pressure in short children born small for gestational age and effects of growth hormone treatment
    Ruben H Willemsen
    Department of Paediatrics, Division of Endocrinology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 69:264-8. 2008
    ..High MMP-9 levels are found in hypertensive patients and predict cardiovascular mortality...
  6. doi Prematurity is not associated with reduced insulin sensitivity in adulthood
    Ruben H Willemsen
    Department of Pediatrics, Division of Endocrinology, Erasmus Medical Centre Sophia, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 94:1695-700. 2009
    ..It is, however, still unknown whether this reduced insulin sensitivity persists into adulthood...
  7. doi Longitudinal changes in insulin sensitivity and body composition of small-for-gestational-age adolescents after cessation of growth hormone treatment
    Ruben H Willemsen
    Department of Pediatrics, Division of Endocrinology, Erasmus Medical Center Sophia, GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 93:3449-54. 2008
    ....
  8. doi Does preterm birth influence the response to growth hormone treatment in short, small for gestational age children?
    Sandra W K de Kort
    Department of Paediatrics, Division of Endocrinology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 70:582-7. 2009
    ..To investigate whether prematurity has an independent influence on the response to GH treatment in short, small for gestational age (SGA) children...
  9. doi Cardiovascular risk factors in parents of short children born small for gestational age
    Sandra W K de Kort
    Department of Pediatrics, Erasmus MC Sophia, Rotterdam, 3015 GJ, The Netherlands
    Pediatr Res 64:91-6. 2008
    ..In conclusion, parents of short SGA children have a modest increase in some cardiovascular risk factors but risk factors did not correlate between parents and children...
  10. doi Does preterm birth influence cardiovascular risk in early adulthood?
    Gerthe F Kerkhof
    Department of Pediatrics, Subdivision of Endocrinology, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    J Pediatr 161:390-396.e1. 2012
    ..To investigate the effect of preterm birth on risk factors for cardiovascular disease (CVD), independent of birth size...
  11. doi The effect of growth hormone treatment on metabolic and cardiovascular risk factors is similar in preterm and term short, small for gestational age children
    Sandra W K de Kort
    Department of Paediatrics, Division of Endocrinology, Erasmus MC Sophia, The Netherlands
    Clin Endocrinol (Oxf) 71:65-73. 2009
    ..Whether preterm birth also influences these parameters during GH treatment is unknown...
  12. doi Influence of preterm birth and birth size on gonadal function in young men
    Gerthe F Kerkhof
    Department of Pediatrics, Subdivision of Endocrinology, Erasmus MC Sophia Children s Hospital, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 94:4243-50. 2009
    ..We hypothesized that alterations concerning gonadal function in young men are not due to preterm birth or being born SGA, but are due to other (environmental) factors...
  13. doi Preterm birth does not affect bone mineral density in young adults
    Petra E Breukhoven
    Subdivision of Endocrinology, Department of Pediatrics, Erasmus MC Sophia Children s Hospital, Room number SB 2603, Dr Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands
    Eur J Endocrinol 164:133-8. 2011
    ..The objective of our study was to assess the long-term effects of preterm birth on BMD of the total body (BMD(TB)), lumbar spine (BMD(LS)) and bone mineral apparent density of the LS (BMAD(LS))...
  14. doi Health profile of young adults born preterm: negative effects of rapid weight gain in early life
    Gerthe F Kerkhof
    Department of Pediatrics, Subdivision of Endocrinology, Erasmus Medical Center Sophia Children s Hospital, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 97:4498-506. 2012
    ..We aimed to investigate the association of weight gain during different periods, and weight trajectories in early life after preterm birth, with determinants of CVD and DM2 in early adulthood...
  15. doi Bloom syndrome in short children born small for gestational age: a challenging diagnosis
    Judith S Renes
    MD, Erasmus Medical Center Sophia Children s Hospital, Dr Molewaterplein 60, Room SB 2603, 3015 GJ Rotterdam, The Netherlands
    J Clin Endocrinol Metab 98:3932-8. 2013
    ....