Tonya White

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc White matter 'potholes' in early-onset schizophrenia: a new approach to evaluate white matter microstructure using diffusion tensor imaging
    Tonya White
    Division of Child and Adolescent Psychiatry, F256 2B, University of Minnesota, Fairview University Medical Center, 2450 Riverside Avenue, Minneapolis, MN 55454, United States
    Psychiatry Res 174:110-5. 2009
  2. doi request reprint Verbal and visuospatial working memory development and deficits in children and adolescents with schizophrenia
    Tonya White
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
    Early Interv Psychiatry 4:305-13. 2010
  3. pmc Spatial characteristics of white matter abnormalities in schizophrenia
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, Rotterdam, The Netherlands
    Schizophr Bull 39:1077-86. 2013
  4. ncbi request reprint Brain connectivity and gyrification as endophenotypes for schizophrenia: weight of the evidence
    T White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, Rotterdam, Netherlands
    Curr Top Med Chem 12:2393-403. 2012
  5. doi request reprint Pediatric population-based neuroimaging and the Generation R Study: the intersection of developmental neuroscience and epidemiology
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre Sophia, Kamer SP 2869, Postbus 2060, 3000 CB Rotterdam, The Netherlands
    Eur J Epidemiol 28:99-111. 2013
  6. doi request reprint Evidence for intact local connectivity but disrupted regional function in the occipital lobe in children and adolescents with schizophrenia
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, Rotterdam, Netherlands
    Hum Brain Mapp 33:1803-11. 2012
  7. doi request reprint Gyrification and neural connectivity in schizophrenia
    Tonya White
    Erasmus Medical Centre, Rotterdam, The Netherlands
    Dev Psychopathol 23:339-52. 2011
  8. pmc Global white matter abnormalities in schizophrenia: a multisite diffusion tensor imaging study
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus University, 3000 CB Rotterdam, The Netherlands
    Schizophr Bull 37:222-32. 2011
  9. pmc Disrupted functional brain connectivity during verbal working memory in children and adolescents with schizophrenia
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands
    Cereb Cortex 21:510-8. 2011
  10. doi request reprint Increased anterior cingulate and temporal lobe activity during visuospatial working memory in children and adolescents with schizophrenia
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus University Medical Center Sophia, Rotterdam, The Netherlands
    Schizophr Res 125:118-28. 2011

Collaborators

Detail Information

Publications38

  1. pmc White matter 'potholes' in early-onset schizophrenia: a new approach to evaluate white matter microstructure using diffusion tensor imaging
    Tonya White
    Division of Child and Adolescent Psychiatry, F256 2B, University of Minnesota, Fairview University Medical Center, 2450 Riverside Avenue, Minneapolis, MN 55454, United States
    Psychiatry Res 174:110-5. 2009
    ..This algorithm may be also be well suited to detect white matter abnormalities in disorders such as substance abuse, head trauma, or specific neurological conditions affecting white matter...
  2. doi request reprint Verbal and visuospatial working memory development and deficits in children and adolescents with schizophrenia
    Tonya White
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
    Early Interv Psychiatry 4:305-13. 2010
    ..Differences in the developmental trajectories in patients compared with controls may reflect differential effects within specific neural networks involved in working memory performance...
  3. pmc Spatial characteristics of white matter abnormalities in schizophrenia
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, Rotterdam, The Netherlands
    Schizophr Bull 39:1077-86. 2013
    ....
  4. ncbi request reprint Brain connectivity and gyrification as endophenotypes for schizophrenia: weight of the evidence
    T White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, Rotterdam, Netherlands
    Curr Top Med Chem 12:2393-403. 2012
    ..Thus, the goal of this paper is to conduct a critical review of the evidence linking both structural and functional connectivity as an endophenotype for schizophrenia...
  5. doi request reprint Pediatric population-based neuroimaging and the Generation R Study: the intersection of developmental neuroscience and epidemiology
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre Sophia, Kamer SP 2869, Postbus 2060, 3000 CB Rotterdam, The Netherlands
    Eur J Epidemiol 28:99-111. 2013
    ..The infusion of imaging into the Generation R Study will set the stage for evaluating the role of multiple environmental and genetic factors in both typical and atypical neurodevelopment...
  6. doi request reprint Evidence for intact local connectivity but disrupted regional function in the occipital lobe in children and adolescents with schizophrenia
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, Rotterdam, Netherlands
    Hum Brain Mapp 33:1803-11. 2012
    ..These results are consistent with abnormalities in regional connectivity with preserved local connectivity in early-onset schizophrenia...
  7. doi request reprint Gyrification and neural connectivity in schizophrenia
    Tonya White
    Erasmus Medical Centre, Rotterdam, The Netherlands
    Dev Psychopathol 23:339-52. 2011
    ..This altered form may provide helpful clues in understanding the neurobiological abnormalities associated with schizophrenia...
  8. pmc Global white matter abnormalities in schizophrenia: a multisite diffusion tensor imaging study
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus University, 3000 CB Rotterdam, The Netherlands
    Schizophr Bull 37:222-32. 2011
    ..Our goal was to assess whether WM findings occurred early in the illness or whether these abnormalities developed with the illness over time...
  9. pmc Disrupted functional brain connectivity during verbal working memory in children and adolescents with schizophrenia
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands
    Cereb Cortex 21:510-8. 2011
    ..Patients with early-onset schizophrenia demonstrate abnormal functional connectivity in networks involving limbic, temporal lobe, cerebellum, and early visual processing streams...
  10. doi request reprint Increased anterior cingulate and temporal lobe activity during visuospatial working memory in children and adolescents with schizophrenia
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus University Medical Center Sophia, Rotterdam, The Netherlands
    Schizophr Res 125:118-28. 2011
    ..The goal of this study was to evaluate the functional neurobiology of WkM in patients with EOS...
  11. pmc Gray matter volume deficits are associated with motor and attentional impairments in adolescents with schizophrenia
    Sanjiv Kumra
    University of Minnesota, Department of Psychiatry, Minneapolis, MN 55454, USA
    Prog Neuropsychopharmacol Biol Psychiatry 35:939-43. 2011
    ..Our findings point to widespread, perhaps multifocal, pathology as contributing to cognitive dysfunction in adolescents with schizophrenia...
  12. doi request reprint Trajectories of social withdrawal and cognitive decline in the schizophrenia prodrome
    Kathryn Cullen
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN, USA
    Clin Schizophr Relat Psychoses 4:229-38. 2011
    ..This study aimed to characterize developmental trajectories of premorbid social withdrawal and cognitive decline between patients with high versus low levels of negative symptoms in youth with schizophrenia-spectrum disorders...
  13. pmc Cigarette smoking and white matter microstructure in schizophrenia
    Kathryn R Cullen
    Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN, USA
    Psychiatry Res 201:152-8. 2012
    ..Further, low FA in specific brain areas may be a neural marker for complex pathophysiology and risk for diverse problems such as schizophrenia, low IQ, and nicotine addiction...
  14. doi request reprint Structural and diffusion tensor imaging of the fornix in childhood- and adolescent-onset schizophrenia
    Mustafa Kendi
    University of Minnesota, Minneapolis, MN 55454, USA
    J Am Acad Child Adolesc Psychiatry 47:826-32. 2008
    ..The fornix is the primary efferent neural pathway of the hippocampus and has been shown to be abnormal in adults with schizophrenia...
  15. pmc MTHFR 677C --> T genotype disrupts prefrontal function in schizophrenia through an interaction with COMT 158Val --> Met
    Joshua L Roffman
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 105:17573-8. 2008
    ..The findings also suggest the importance of weighing COMT effects on prefrontal function within the context of MTHFR genotype...
  16. pmc Oculomotor and pupillometric indices of pro- and antisaccade performance in youth-onset psychosis and attention deficit/hyperactivity disorder
    Canan Karatekin
    Institute of Child Development, University of Minnesota, 51 East River Road, Minneapolis, MN 55455, USA
    Schizophr Bull 36:1167-86. 2010
    ..Thus, results show inhibitory deficits in the context of more general attentional impairments in both disorders...
  17. ncbi request reprint Disruption of hippocampal connectivity in children and adolescents with schizophrenia--a voxel-based diffusion tensor imaging study
    Tonya White
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55454, USA
    Schizophr Res 90:302-7. 2007
    ..As white matter provides rapid and efficient communication between brain regions, this study was initiated to assess the early disruption of white matter pathways in children and adolescent with schizophrenia...
  18. pmc Differential fractional anisotropy abnormalities in adolescents with ADHD or schizophrenia
    Nicholas D Davenport
    Department of Psychology, University of Minnesota, Minneapolis, MN, United States
    Psychiatry Res 181:193-8. 2010
    ....
  19. pmc Regulation of cognitive resources during an n-back task in youth-onset psychosis and attention-deficit/hyperactivity disorder (ADHD)
    Canan Karatekin
    Institute of Child Development, University of Minnesota, 51 East River Road, Minneapolis, MN 55455, United States
    Int J Psychophysiol 73:294-307. 2009
    ..It is likely that these attentional problems prevented the clinical groups from encoding the stimuli effectively and contributed to their general performance deficits...
  20. pmc Shared and nonshared symptoms in youth-onset psychosis and ADHD
    Canan Karatekin
    Institute of Child Development, University of Minnesota, Minneapolis, MN 55455, USA
    J Atten Disord 14:121-31. 2010
    ..We compared ratings of behavior and attention problems between youth-onset psychosis and ADHD, two disorders in which attentional impairments play a key role, and examined the effect of psychostimulant use on age of onset in psychosis...
  21. doi request reprint Clinical and neurocognitive course in early-onset psychosis: a longitudinal study of adolescents with schizophrenia-spectrum disorders
    Jeffrey R Wozniak
    Department of Psychiatry, University of Minnesota Medical Center Twin Cities, Minneapolis, Minnesota 55454, USA
    Early Interv Psychiatry 2:169-77. 2008
    ..The goals of this study were to examine these relationships in a larger sample at baseline, and also to examine the longitudinal course of these deficits in a smaller subset of adolescents...
  22. doi request reprint Divided attention in youth-onset psychosis and attention deficit/hyperactivity disorder
    Canan Karatekin
    Institute of Child Development, University of Minnesota, 51 East River Road, Minneapolis, MN 55455, USA
    J Abnorm Psychol 117:881-95. 2008
    ..Findings also demonstrate the importance of taking into account difficulties that constrain performance on simple tasks before interpreting impairments on complex tasks...
  23. ncbi request reprint Variations in the catechol O-methyltransferase polymorphism and prefrontally guided behaviors in adolescents
    Dustin Wahlstrom
    Department of Psychology, Center for Neurobehavorial Development, University of Minnesota Twin Cities, Minneapolis, Minnesota 55455, USA
    Biol Psychiatry 61:626-32. 2007
    ..These genotypic variations and their associations with executive functions have been described in adults and prepubescent children, but there is a paucity of research assessing these relations in adolescent samples...
  24. pmc Limbic structures and networks in children and adolescents with schizophrenia
    Tonya White
    Department of Psychiatry, Fairview University Medical Center, University of Minnesota, Minneapolis, MN 55454, USA
    Schizophr Bull 34:18-29. 2008
    ..Additional research within a developmental framework is necessary to determine the putative etiologic roles for limbic and other brain abnormalities in early-onset schizophrenia...
  25. doi request reprint A comparative pilot study of second-generation antipsychotics in children and adolescents with schizophrenia-spectrum disorders
    Jonathan B Jensen
    University of Minnesota, Department of Psychiatry, Minneapolis, Minnesota 55454, USA
    J Child Adolesc Psychopharmacol 18:317-26. 2008
    ..To plan the design of a subsequent randomized controlled trial (RCT), the authors conducted this pilot study to demonstrate the feasibility of the treatment and measurement protocols...
  26. ncbi request reprint Neuropsychological performance in first-episode adolescents with schizophrenia: a comparison with first-episode adults and adolescent control subjects
    Tonya White
    Division of Child and Adolescent Psychiatry, Center for Neurobehavioral Development, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Biol Psychiatry 60:463-71. 2006
    ..The goal of this study was to compare the extent of cognitive deficits between adolescents and adults early in the course of schizophrenia...
  27. doi request reprint Infant brain structures, executive function, and attention deficit/hyperactivity problems at preschool age. A prospective study
    Akhgar Ghassabian
    The Generation R Study Group, Erasmus MC Department of Child and Adolescent Psychiatry, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    J Child Psychol Psychiatry 54:96-104. 2013
    ..In a population-based study, we aimed to characterize the prospective association between brain structures measured during infancy and executive function and attention deficit/hyperactivity problems assessed at preschool age...
  28. pmc Developmental changes in dopamine neurotransmission in adolescence: behavioral implications and issues in assessment
    Dustin Wahlstrom
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Brain Cogn 72:146-59. 2010
    ..Furthermore, we will suggest how these techniques can be combined with other methods such as pharmacology to measure the impact of dopamine activity on behavior and how this relation changes through the lifespan...
  29. ncbi request reprint The schizophrenia prodrome
    Tonya White
    Department of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Am J Psychiatry 163:376-80. 2006
  30. pmc The MCIC collection: a shared repository of multi-modal, multi-site brain image data from a clinical investigation of schizophrenia
    Randy L Gollub
    Department of Psychiatry, Massachusetts General Hospital, Building 120, Suite 101D, Charlestown, MA 02129 2000, USA
    Neuroinformatics 11:367-88. 2013
    ..This manuscript describes the inclusion/exclusion criteria, imaging parameters and other information that will assist those wishing to use this data repository. ..
  31. pmc Neurobehavioral evidence for changes in dopamine system activity during adolescence
    Dustin Wahlstrom
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Neurosci Biobehav Rev 34:631-48. 2010
    ..Implications for the understanding of adolescent behavioral development are discussed...
  32. doi request reprint Diffusion tensor imaging in psychiatric disorders
    Tonya White
    Department of Psychiatry, University of Minnesota, Fairview University Medical Center, 2450 Riverside Ave, Minneapolis, MN 55454, USA
    Top Magn Reson Imaging 19:97-109. 2008
    ..The goal of this article is to provide an overview of DTI and its application to psychiatric disorders...
  33. pmc The development of gyrification in childhood and adolescence
    Tonya White
    Department of Child and Adolescent Psychiatry, Erasmus Medical Centre, Rotterdam, The Netherlands
    Brain Cogn 72:36-45. 2010
    ..We also present recent findings involving alterations in gyrification during childhood and adolescence...
  34. doi request reprint Adherence and psychopathology in children and adolescents with cystic fibrosis
    Tonya White
    University of Minnesota, Minneapolis, 55454, USA
    Eur Child Adolesc Psychiatry 18:96-104. 2009
    ..The objective of this study was to investigate the association between psychopathology and treatment adherence in children and adolescents with CF...
  35. ncbi request reprint Adaptation and adjustment in children of transsexual parents
    Tonya White
    Division of Child and Adolescent Psychiatry, Dept of Psychiatry, University of Minnesota School of Medicine, Minneapolis, MN 55454, USA
    Eur Child Adolesc Psychiatry 16:215-21. 2007
    ..In addition, parental conflict that continues after the transition period tends to reflect greater family conflict between the transitioned parent and their child...
  36. ncbi request reprint Oculomotor and manual indexes of incidental and intentional spatial sequence learning during middle childhood and adolescence
    Canan Karatekin
    Institute of Child Development, University of Minnesota, Minneapolis, MN 55455, USA
    J Exp Child Psychol 96:107-30. 2007
    ..In contrast, the ability to learn a sequence intentionally, which requires cognitive resources and strategies, continues to develop through adolescence...
  37. pmc Noninvasive quantification of ascorbate and glutathione concentration in the elderly human brain
    Uzay E Emir
    Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, USA
    NMR Biomed 24:888-94. 2011
    ..In conclusion, GSH and Asc concentrations were compared noninvasively for the first time in young vs elderly subjects...
  38. ncbi request reprint Affective bias and response modulation following tyrosine depletion in healthy adults
    Suzanne Vrshek-Schallhorn
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Neuropsychopharmacology 31:2523-36. 2006
    ..Basic motor functions were not impacted. Findings are discussed in relation to dopamine's role in switching signals within neural networks that are important for response modulation and affective control...