Georges M G M Verjans
Affiliation: Erasmus MC
Country: The Netherlands
Verjans G, Hintzen R, van Dun J, Poot A, Milikan J, Laman J, et al
. Selective retention of herpes simplex virus-specific T cells in latently infected human trigeminal ganglia. Proc Natl Acad Sci U S A. 2007;104:3496-501 pubmed
..In contrast, T cells do not seem to be directly involved in controlling VZV latency in human TG. ..
Depledge D, Ouwendijk W, Sadaoka T, Braspenning S, Mori Y, Cohrs R, et al
. A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61. Nat Commun. 2018;9:1167 pubmed publisher
..The discovery of VLT links VZV with the other better characterized human and animal neurotropic alphaherpesviruses and provides insights into VZV latency. ..
Ouwendijk W, van Veen S, Mehraban T, Mahalingam R, Verjans G. Simian Varicella Virus Infects Enteric Neurons and ?4?7 Integrin-Expressing Gut-Tropic T-Cells in Nonhuman Primates. Viruses. 2018;10: pubmed publisher
..Because SVV reactivation can be experimentally induced, the SVV nonhuman primate model holds great potential to study the pathogenesis of enteric zoster. ..
van Nierop G, Mautner J, Mitterreiter J, Hintzen R, Verjans G. Intrathecal CD8 T-cells of multiple sclerosis patients recognize lytic Epstein-Barr virus proteins. Mult Scler. 2016;22:279-91 pubmed publisher
..Our data warrant further characterization of the magnitude and breadth of intrathecal EBV-specific T-cell responses in larger patient cohorts. ..
van Elk C, van de Bildt M, van Run P, de Jong A, Getu S, Verjans G, et al
. Central nervous system disease and genital disease in harbor porpoises (Phocoena phocoena) are associated with different herpesviruses. Vet Res. 2016;47:28 pubmed publisher
..In conclusion, harbor porpoises may be infected with at least three different herpesviruses, one of which can cause clinically severe neurological disease. ..
Schaftenaar E, Peters R, Baarsma G, Meenken C, Khosa N, Getu S, et al
. Clinical and corneal microbial profile of infectious keratitis in a high HIV prevalence setting in rural South Africa. Eur J Clin Microbiol Infect Dis. 2016;35:1403-9 pubmed publisher
..The data implicate a high prevalence of herpetic keratitis, in part complicated by bacterial superinfection and/or uveitis, in HIV-infected individuals presenting with infectious keratitis in rural South Africa. ..
van Nierop G, van Luijn M, Michels S, Melief M, Janssen M, Langerak A, et al
. Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients. Acta Neuropathol. 2017;134:383-401 pubmed publisher
..Collectively, the data suggest the involvement of effector memory cytotoxic T cells recognizing antigens expressed by autoBLCL, but not the assayed human cMSAg, in WML of MS patients. ..