G M Verjans

Summary

Affiliation: Erasmus University
Country: The Netherlands

Publications

  1. ncbi request reprint Restricted T cell receptor beta-chain variable region protein use by cornea-derived CD4+ and CD8+ herpes simplex virus-specific T cells in patients with herpetic stromal keratitis
    Jeroen Maertzdorf
    Institute of Virology, Erasmus Medical Centre, Erasmus, The Netherlands
    J Infect Dis 187:550-8. 2003
  2. ncbi request reprint Identification and characterization of herpes simplex virus-specific CD4+ T cells in corneas of herpetic stromal keratitis patients
    G M Verjans
    Rotterdam Eye Hospital, Institute of Virology, Erasmus University Rotterdam, The Netherlands
    J Infect Dis 177:484-8. 1998
  3. ncbi request reprint Vgamma9Vdelta2 T cells recovered from eyes of patients with Behçet's disease recognize non-peptide prenyl pyrophosphate antigens
    Georges M G M Verjans
    Rotterdam Eye Hospital, PO Box 70030, 3000 LM, Rotterdam, The Netherlands
    J Neuroimmunol 130:46-54. 2002
  4. ncbi request reprint Intraocular T cells of patients with herpes simplex virus (HSV)-induced acute retinal necrosis recognize HSV tegument proteins VP11/12 and VP13/14
    G M Verjans
    Institute of Virology, Erasmus University Rotterdam, 3000 DR Rotterdam, The Netherlands
    J Infect Dis 182:923-7. 2000
  5. ncbi request reprint Herpes simplex virus-specific T cells infiltrate the cornea of patients with herpetic stromal keratitis: no evidence for autoreactive T cells
    G M Verjans
    Rotterdam Eye Hospital, Institute of Virology, Erasmus University Rotterdam, The Netherlands
    Invest Ophthalmol Vis Sci 41:2607-12. 2000
  6. ncbi request reprint T cells specific for the triggering virus infiltrate the eye in patients with herpes simplex virus-mediated acute retinal necrosis
    G M Verjans
    Rotterdam Eye Hospital, and Institute of Virology, Erasmus University Rotterdam, The Netherlands
    J Infect Dis 178:27-34. 1998
  7. ncbi request reprint Herpes simplex virus type 1 (HSV-1)--induced retinitis following herpes simplex encephalitis: indications for brain-to-eye transmission of HSV-1
    J Maertzdorf
    Department of Virology, Erasmus University, Rotterdam, The Netherlands
    Ann Neurol 49:104-6. 2001
  8. ncbi request reprint Characterization of Toxoplasma gondii-specific T cells recovered from vitreous fluid of patients with ocular toxoplasmosis
    E J Feron
    The Rotterdam Eye Hospital, Rotterdam, The Netherlands
    Invest Ophthalmol Vis Sci 42:3228-32. 2001
  9. ncbi request reprint Prevalence and association between herpes simplex virus types 1 and 2-specific antibodies in attendees at a sexually transmitted disease clinic
    R W Roest
    Department of Dermatology and Venereology, University Hospital Rotterdam Dijkzigt and Erasmus University Rotterdam, The Netherlands
    Int J Epidemiol 30:580-8. 2001
  10. ncbi request reprint Characterization of the varicella zoster virus (VZV)-specific intra-ocular T-cell response in patients with VZV-induced uveitis
    Johannes C M Milikan
    Institute of Virology, Erasmus Medical Center, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
    Exp Eye Res 83:69-75. 2006

Collaborators

  • V N Klaren
  • P Hoogerhout
  • J Groen
  • R W Roest
  • Johannes C M Milikan
  • Albert D M E Osterhaus
  • Rui Duan
  • G Seerp Baarsma
  • Robert W A M Kuijpers
  • Lies Remeijer
  • Jeroen Maertzdorf
  • Ron Peek
  • E J Feron
  • J Maertzdorf
  • Jessica M van Dun
  • Paul R Kinchington
  • Alexander van der Kooi
  • Bob Meek
  • A Van der Lelij
  • A D Osterhaus
  • E A Wierenga
  • G S Baarsma
  • A Kijlstra

Detail Information

Publications14

  1. ncbi request reprint Restricted T cell receptor beta-chain variable region protein use by cornea-derived CD4+ and CD8+ herpes simplex virus-specific T cells in patients with herpetic stromal keratitis
    Jeroen Maertzdorf
    Institute of Virology, Erasmus Medical Centre, Erasmus, The Netherlands
    J Infect Dis 187:550-8. 2003
    ..The data demonstrate that both CD4(+) and CD8(+) T cells may be involved in the HSV-specific T cell response in the corneas of patients with HSK and suggest that restricted TCRBV use by cornea-residing HSV-specific T cells occurs...
  2. ncbi request reprint Identification and characterization of herpes simplex virus-specific CD4+ T cells in corneas of herpetic stromal keratitis patients
    G M Verjans
    Rotterdam Eye Hospital, Institute of Virology, Erasmus University Rotterdam, The Netherlands
    J Infect Dis 177:484-8. 1998
    ..The data presented suggest that HSV-specific CD4+ T cells play a role in the immunopathogenesis of HSK in humans and that corneal keratocytes may act as antigen-presenting cells in this local T cell response...
  3. ncbi request reprint Vgamma9Vdelta2 T cells recovered from eyes of patients with Behçet's disease recognize non-peptide prenyl pyrophosphate antigens
    Georges M G M Verjans
    Rotterdam Eye Hospital, PO Box 70030, 3000 LM, Rotterdam, The Netherlands
    J Neuroimmunol 130:46-54. 2002
    ..The data presented suggest the infiltration of PPP-specific Vgamma9Vdelta2 Th1-like cells into the eye of BD patients with uveitis...
  4. ncbi request reprint Intraocular T cells of patients with herpes simplex virus (HSV)-induced acute retinal necrosis recognize HSV tegument proteins VP11/12 and VP13/14
    G M Verjans
    Institute of Virology, Erasmus University Rotterdam, 3000 DR Rotterdam, The Netherlands
    J Infect Dis 182:923-7. 2000
    ..Analysis of the data indicates that HSV-1 VP11/12 and VP13/14 are major target antigens for T cells obtained from vitreous fluid samples of the HSV-induced ARN patients studied...
  5. ncbi request reprint Herpes simplex virus-specific T cells infiltrate the cornea of patients with herpetic stromal keratitis: no evidence for autoreactive T cells
    G M Verjans
    Rotterdam Eye Hospital, Institute of Virology, Erasmus University Rotterdam, The Netherlands
    Invest Ophthalmol Vis Sci 41:2607-12. 2000
    ..Whether this type of autoimmunity plays a role in human HSK was analyzed...
  6. ncbi request reprint T cells specific for the triggering virus infiltrate the eye in patients with herpes simplex virus-mediated acute retinal necrosis
    G M Verjans
    Rotterdam Eye Hospital, and Institute of Virology, Erasmus University Rotterdam, The Netherlands
    J Infect Dis 178:27-34. 1998
    ..67-0.73 HSV-1 map units. The data presented suggest the contribution of T cells, specific for the triggering virus, to the pathogenesis of ARN...
  7. ncbi request reprint Herpes simplex virus type 1 (HSV-1)--induced retinitis following herpes simplex encephalitis: indications for brain-to-eye transmission of HSV-1
    J Maertzdorf
    Department of Virology, Erasmus University, Rotterdam, The Netherlands
    Ann Neurol 49:104-6. 2001
    ..The HSV-1 strains in both the brain and eye were identical in each patient, but they differed interindividually. The data suggest brain-to-eye transmission of HSV-1 in these patients...
  8. ncbi request reprint Characterization of Toxoplasma gondii-specific T cells recovered from vitreous fluid of patients with ocular toxoplasmosis
    E J Feron
    The Rotterdam Eye Hospital, Rotterdam, The Netherlands
    Invest Ophthalmol Vis Sci 42:3228-32. 2001
    ..The functional characteristics of the VF-derived Tg-specific T cells and their presence at the site of inflammation suggest their involvement in the local inflammatory response of ocular toxoplasmosis...
  9. ncbi request reprint Prevalence and association between herpes simplex virus types 1 and 2-specific antibodies in attendees at a sexually transmitted disease clinic
    R W Roest
    Department of Dermatology and Venereology, University Hospital Rotterdam Dijkzigt and Erasmus University Rotterdam, The Netherlands
    Int J Epidemiol 30:580-8. 2001
    ..Correlations of HSV-1 and HSV-2 seropositivity were investigated. The relationship between HSV-1 and HSV-2 antibodies was also studied...
  10. ncbi request reprint Characterization of the varicella zoster virus (VZV)-specific intra-ocular T-cell response in patients with VZV-induced uveitis
    Johannes C M Milikan
    Institute of Virology, Erasmus Medical Center, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
    Exp Eye Res 83:69-75. 2006
    ..The data implicate that VZV-reactive T-cells infiltrate and participate in the local inflammatory response in eyes of patients with VZV-induced uveitis...
  11. ncbi request reprint Identification of viral antigens recognized by ocular infiltrating T cells from patients with varicella zoster virus-induced uveitis
    Johannes C M Milikan
    Institute of Virology, Erasmus Medical Center, Rotterdam
    Invest Ophthalmol Vis Sci 48:3689-97. 2007
    ..In the current study, the functional characteristics and the antigen specificity of VZV-reactive T cells recovered from intraocular fluid (IOF) samples of five patients with VZV were determined...
  12. ncbi request reprint Isopentenyl pyrophosphate-reactive Vgamma9Vdelta 2 T helper 1-like cells are the major gammadelta T cell subset recovered from lesions of patients with genital herpes
    Georges M G M Verjans
    Institute of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Infect Dis 190:489-93. 2004
    ..The results of the present study suggest the infiltration and putative involvement of isopentenyl pyrophosphate-reactive V gamma 9V delta 2 T helper 1-like cells in individuals with GH...
  13. ncbi request reprint Granulocyte macrophage colony-stimulating factor expression in human herpetic stromal keratitis: implications for the role of neutrophils in HSK
    Rui Duan
    Institute of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Invest Ophthalmol Vis Sci 48:277-84. 2007
    ..The objective of this study was to determine the putative role of GM-CSF in the pathogenesis of human herpetic stromal keratitis (HSK)...
  14. ncbi request reprint Herpes simplex virus infection of the human eye induces a compartmentalized virus-specific B cell response
    Ron Peek
    Netherlands Ophthalmic Research Institute, Amsterdam, The Netherlands
    J Infect Dis 186:1539-46. 2002
    ..The results presented here indicate that the inflamed eyes of patients with HSV-induced uveitis display a compartmentalized B cell response directed toward the triggering virus...