V H van der Velden

Summary

Affiliation: Erasmus University
Country: The Netherlands

Publications

  1. ncbi request reprint Interleukin-1beta and interferon-gamma differentially regulate release of monocyte chemotactic protein-1 and interleukin-8 by human bronchial epithelial cells
    V H van der Velden
    Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands
    Eur Cytokine Netw 9:269-77. 1998
  2. ncbi request reprint Cytokines and glucocorticoids modulate human bronchial epithelial cell peptidases
    V H van der Velden
    Department of Immunology, Erasmus University, Rotterdam, The Netherlands
    Cytokine 10:55-65. 1998
  3. pmc Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthma
    V H van der Velden
    Department of Immunology, Erasmus University, Rotterdam, The Netherlands
    Mediators Inflamm 7:229-37. 1998
  4. ncbi request reprint Interleukin 4 receptors on human bronchial epithelial cells. An in vivo and in vitro analysis of expression and function
    V H van der Velden
    Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands
    Cytokine 10:803-13. 1998
  5. ncbi request reprint Bronchial epithelium: morphology, function and pathophysiology in asthma
    V H Velden
    Department of Immunology, Erasmus University Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands Tel 31 10 4088253, Fax 31 10 4367601, E mail
    Eur Cytokine Netw 9:585-97. 1998
  6. ncbi request reprint Selective development of a strong Th2 cytokine profile in high-risk children who develop atopy: risk factors and regulatory role of IFN-gamma, IL-4 and IL-10
    V H van der Velden
    Department of Immunology, Erasmus University University Hospital Rotterdam, Department of Paediatrics, Sophia Children s Hospital, 3000 DR Rotterdam, The Netherlands
    Clin Exp Allergy 31:997-1006. 2001
  7. ncbi request reprint Expression of aminopeptidase N and dipeptidyl peptidase IV in the healthy and asthmatic bronchus
    V H van der Velden
    Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands
    Clin Exp Allergy 28:110-20. 1998
  8. ncbi request reprint Clearance of maternal leukaemic cells in a neonate
    V H van der Velden
    Department of Immunology, Erasmus University Rotterdam/University Hospital Rotterdam, Rotterdam, The Netherlands
    Br J Haematol 114:104-6. 2001
  9. ncbi request reprint Human keratinocytes are major producers of IL-18: predominant expression of the unprocessed form
    A R Companjen
    Department of Immunology, Erasmus University Rotterdam EUR, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Eur Cytokine Netw 11:383-90. 2000
  10. ncbi request reprint Autonomic innervation of human airways: structure, function, and pathophysiology in asthma
    V H van der Velden
    Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands
    Neuroimmunomodulation 6:145-59. 1999

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Interleukin-1beta and interferon-gamma differentially regulate release of monocyte chemotactic protein-1 and interleukin-8 by human bronchial epithelial cells
    V H van der Velden
    Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands
    Eur Cytokine Netw 9:269-77. 1998
    ..Finally, the beneficial effect of glucocorticoid therapy in airway inflammatory diseases may be mediated in part by inhibition of chemokine release and ICAM-1, CD40, and HLA class II expression by bronchial epithelial cells...
  2. ncbi request reprint Cytokines and glucocorticoids modulate human bronchial epithelial cell peptidases
    V H van der Velden
    Department of Immunology, Erasmus University, Rotterdam, The Netherlands
    Cytokine 10:55-65. 1998
    ..Our results suggest a role for the human bronchial epithelium in the control of inflammation and indicate that one beneficial effect of glucocorticoids on asthma may be upregulation of peptidases expressed by bronchial epithelial cells...
  3. pmc Glucocorticoids: mechanisms of action and anti-inflammatory potential in asthma
    V H van der Velden
    Department of Immunology, Erasmus University, Rotterdam, The Netherlands
    Mediators Inflamm 7:229-37. 1998
    ..Since bronchial epithelial cells may be important targets for glucocorticoid therapy in asthma, the effects of glucocorticoids on epithelial expressed inflammatory genes will be emphasized...
  4. ncbi request reprint Interleukin 4 receptors on human bronchial epithelial cells. An in vivo and in vitro analysis of expression and function
    V H van der Velden
    Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands
    Cytokine 10:803-13. 1998
    ..Stimulation of human bronchial epithelial cells by IL-4 may result in the release of both pro- and anti-inflammatory mediators known to be upregulated in asthmatic airways...
  5. ncbi request reprint Bronchial epithelium: morphology, function and pathophysiology in asthma
    V H Velden
    Department of Immunology, Erasmus University Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands Tel 31 10 4088253, Fax 31 10 4367601, E mail
    Eur Cytokine Netw 9:585-97. 1998
    ..In this review, the morphology of the bronchial epithelium, its function with regard to host defense, and its immunological potential will be reviewed. Alterations associated with asthma will be emphasized...
  6. ncbi request reprint Selective development of a strong Th2 cytokine profile in high-risk children who develop atopy: risk factors and regulatory role of IFN-gamma, IL-4 and IL-10
    V H van der Velden
    Department of Immunology, Erasmus University University Hospital Rotterdam, Department of Paediatrics, Sophia Children s Hospital, 3000 DR Rotterdam, The Netherlands
    Clin Exp Allergy 31:997-1006. 2001
    ..The immunological processes in early life and their relation to allergic sensitization leading to a Th2 cytokine profile are still not well understood...
  7. ncbi request reprint Expression of aminopeptidase N and dipeptidyl peptidase IV in the healthy and asthmatic bronchus
    V H van der Velden
    Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands
    Clin Exp Allergy 28:110-20. 1998
    ..The effects of peptides are modulated by peptidases, which are able to degrade peptides, mostly resulting in their inactivation...
  8. ncbi request reprint Clearance of maternal leukaemic cells in a neonate
    V H van der Velden
    Department of Immunology, Erasmus University Rotterdam/University Hospital Rotterdam, Rotterdam, The Netherlands
    Br J Haematol 114:104-6. 2001
    ..In the cord blood sample, a tumour load of approximately 4 x 10(-4) was found, whereas all later blood samples were negative. Our data indicate that the maternal leukaemic cells did not engraft in the neonate...
  9. ncbi request reprint Human keratinocytes are major producers of IL-18: predominant expression of the unprocessed form
    A R Companjen
    Department of Immunology, Erasmus University Rotterdam EUR, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Eur Cytokine Netw 11:383-90. 2000
    ..High constitutive levels of IL-18 may contribute to the skewing towards a Th1-like environment, which is apparent in many human inflammatory skin diseases...
  10. ncbi request reprint Autonomic innervation of human airways: structure, function, and pathophysiology in asthma
    V H van der Velden
    Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands
    Neuroimmunomodulation 6:145-59. 1999
    ..On the other hand, inflammatory cells may modulate the neuronal phenotype and function. The functional relevance of the excitatory NANC nervous system and its interaction with the immune system in asthma still remains to be elucidated...
  11. ncbi request reprint Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells
    V H van der Velden
    Department of Immunology, Erasmus University Rotterdam and University Hospital Rotterdam, The Netherlands
    Blood 97:3197-204. 2001
    ..Finally, Mylotarg induced dose-dependent apoptosis in myeloid cells in vitro. These data indicate that Mylotarg is rapidly and specifically targeted to CD33(+) cells, followed by internalization and subsequent induction of cell death...
  12. ncbi request reprint Minimal residual disease in leukaemia patients
    T Szczepanski
    Department of Immunology, University Hospital Rotterdam Erasmus University Rotterdam, The Netherlands
    Lancet Oncol 2:409-17. 2001
    ..MRD monitoring is also possible in other leukaemia subtypes, but in these disorders the clinical value of MRD detection is not yet known...