M E van Leerdam

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. doi request reprint Epidemiology of acute upper gastrointestinal bleeding
    M E van Leerdam
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center s, Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Best Pract Res Clin Gastroenterol 22:209-24. 2008
  2. pmc Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management
    Dewkoemar Ramsoekh
    Department of Gastroenterology and Hepatology Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Hered Cancer Clin Pract 7:17. 2009
  3. pmc Study protocol: population screening for colorectal cancer by colonoscopy or CT colonography: a randomized controlled trial
    Thomas R de Wijkerslooth
    Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands
    BMC Gastroenterol 10:47. 2010
  4. doi request reprint Screening for colorectal cancer: comparison of perceived test burden of guaiac-based faecal occult blood test, faecal immunochemical test and flexible sigmoidoscopy
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Eur J Cancer 46:2059-66. 2010
  5. doi request reprint What influences the decision to participate in colorectal cancer screening with faecal occult blood testing and sigmoidoscopy?
    L van Dam
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, The Netherlands
    Eur J Cancer 49:2321-30. 2013
  6. doi request reprint Immunochemical fecal occult blood testing is equally sensitive for proximal and distal advanced neoplasia
    T R de Wijkerslooth
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
    Am J Gastroenterol 107:1570-8. 2012
  7. pmc Quality of life in participants of a CRC screening program
    A Kapidzic
    Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands
    Br J Cancer 107:1295-301. 2012
  8. doi request reprint Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Gut 59:62-8. 2010
  9. doi request reprint Advance notification letters increase adherence in colorectal cancer screening: a population-based randomized trial
    A H C van Roon
    Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Prev Med 52:448-51. 2011
  10. doi request reprint Systematic literature review and pooled analyses of risk factors for finding adenomas at surveillance colonoscopy
    V de Jonge
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Endoscopy 43:560-72. 2011

Collaborators

  • E J Kuipers
  • L Hol
  • E W Steyerberg
  • D Ramsoekh
  • I J Korfage
  • P M Bossuyt
  • G N J Tytgat
  • A C Poen
  • J T Brouwer
  • R A Kraaijenhagen
  • G A Meijer
  • A van der Ende
  • D Dooijes
  • S J O Veldhuyzen van Zanten
  • L van Dam
  • M G F van Lier
  • M van Ballegooijen
  • A H C van Roon
  • J Sint Nicolaas
  • E M Stoop
  • T R de Wijkerslooth
  • V de Jonge
  • A Wagner
  • P Fockens
  • E Dekker
  • J C I Y Reijerink
  • E M H Mathus-Vliegen
  • J Stoker
  • A Kapidzic
  • P G van Putten
  • F ter Borg
  • C H M Leenen
  • J D F Habbema
  • Thomas R de Wijkerslooth
  • M Thomeer
  • M C de Haan
  • W Lesterhuis
  • J J Koornstra
  • A G Zauber
  • M J L Romberg-Camps
  • R P R Adang
  • R J Th Ouwendijk
  • I Stegeman
  • D L Cahen
  • R Timmer
  • R Reddingius
  • C M J Tops
  • J A Wilschut
  • A J van Vuuren
  • A M van den Ouweland
  • W R R Geurts-Giele
  • W N M Dinjens
  • H M van de Klift
  • H J Dubbink
  • Esther M Stoop
  • Marjolein van Ballegooijen
  • Jaap Stoker
  • Marije Deutekom
  • S J O Veldhuyzen-van Zanten
  • Paul Fockens
  • E W de Bekker-Grob
  • K Vanheusden
  • Marie Louise Essink-Bot
  • Evelien Dekker
  • Margriet C de Haan
  • M L Essink-Bot
  • Maarten Thomeer
  • C W N Looman

Detail Information

Publications31

  1. doi request reprint Epidemiology of acute upper gastrointestinal bleeding
    M E van Leerdam
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center s, Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Best Pract Res Clin Gastroenterol 22:209-24. 2008
    ..H. pylori infection is found in about 50% of peptic ulcer bleeding patients. H. pylori should be tested for in all ulcer patients and eradication should be given...
  2. pmc Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management
    Dewkoemar Ramsoekh
    Department of Gastroenterology and Hepatology Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Hered Cancer Clin Pract 7:17. 2009
    ..The risk is dependent of the affected mismatch repair gene. The aim of the present study was to calculate the cumulative risk of LS related cancers in proven MLH1, MSH2 and MSH6 mutation carriers...
  3. pmc Study protocol: population screening for colorectal cancer by colonoscopy or CT colonography: a randomized controlled trial
    Thomas R de Wijkerslooth
    Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands
    BMC Gastroenterol 10:47. 2010
    ....
  4. doi request reprint Screening for colorectal cancer: comparison of perceived test burden of guaiac-based faecal occult blood test, faecal immunochemical test and flexible sigmoidoscopy
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Eur J Cancer 46:2059-66. 2010
    ....
  5. doi request reprint What influences the decision to participate in colorectal cancer screening with faecal occult blood testing and sigmoidoscopy?
    L van Dam
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, The Netherlands
    Eur J Cancer 49:2321-30. 2013
    ..Uptake is an important determinant of the effectiveness of population-based screening. Uptake of colorectal cancer (CRC) screening generally remains sub-optimal...
  6. doi request reprint Immunochemical fecal occult blood testing is equally sensitive for proximal and distal advanced neoplasia
    T R de Wijkerslooth
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
    Am J Gastroenterol 107:1570-8. 2012
    ..Fecal immunochemical testing (FIT) is increasingly used for colorectal cancer (CRC) screening. We aimed to estimate its diagnostic accuracy in invitational population screening measured against colonoscopy...
  7. pmc Quality of life in participants of a CRC screening program
    A Kapidzic
    Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands
    Br J Cancer 107:1295-301. 2012
    ..These findings, however, are important to evaluate the impact of CRC screening...
  8. doi request reprint Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Gut 59:62-8. 2010
    ..We conducted a randomised trial comparing participation and detection rates (DR) per screenee of guaiac-based faecal occult blood test (gFOBT), immunochemical FOBT (FIT), and flexible sigmoidoscopy (FS) for CRC screening...
  9. doi request reprint Advance notification letters increase adherence in colorectal cancer screening: a population-based randomized trial
    A H C van Roon
    Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Prev Med 52:448-51. 2011
    ..An advance notification letter may increase adherence, however, no population-based randomized trials have been conducted to provide evidence of this...
  10. doi request reprint Systematic literature review and pooled analyses of risk factors for finding adenomas at surveillance colonoscopy
    V de Jonge
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Endoscopy 43:560-72. 2011
    ..This variation also affects adherence. Surveillance intervals need to be based on risk factors at index. We therefore aimed to systematically review risk factors of adenoma findings at surveillance colonoscopy...
  11. doi request reprint What determines individuals' preferences for colorectal cancer screening programmes? A discrete choice experiment
    L van Dam
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, Room Ba 393, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Eur J Cancer 46:150-9. 2010
    ..In many countries uptake of colorectal cancer (CRC) screening remains low...
  12. doi request reprint Time requirements and health effects of participation in colorectal cancer screening with colonoscopy or computed tomography colonography in a randomized controlled trial
    L van Dam
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, 3015 CE Rotterdam, The Netherlands
    Endoscopy 45:182-8. 2013
    ..The aim of the study was to measure the time requirements and health effects of colonoscopy and computed tomography colonography (CTC) screening...
  13. doi request reprint High cancer risk in Peutz-Jeghers syndrome: a systematic review and surveillance recommendations
    M G F van Lier
    Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Am J Gastroenterol 105:1258-64; author reply 1265. 2010
    ..We therefore performed a systematic review to assess cancer risks in PJS patients and used these data to develop a surveillance recommendation...
  14. doi request reprint Mutation prediction models in Lynch syndrome: evaluation in a clinical genetic setting
    D Ramsoekh
    Department of Gastroenterology and Hepatology and Department of Public Health, Erasmus MC University Medical Center, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    J Med Genet 46:745-51. 2009
    ..Prediction models have therefore been developed, but they have not been validated for a clinical genetic setting. The aim of the present study was to evaluate the usefulness of currently available prediction models...
  15. pmc Screening for colorectal cancer: random comparison of guaiac and immunochemical faecal occult blood testing at different cut-off levels
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
    Br J Cancer 100:1103-10. 2009
    ..From our experience, a cut-off value of 75 ng ml(-1) provided an adequate positivity rate and an acceptable trade-off between detection rate and NNscope...
  16. doi request reprint Review article: Detection and management of hereditary non-polyposis colorectal cancer (Lynch syndrome)
    D Ramsoekh
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Aliment Pharmacol Ther 26:101-11. 2007
    ..The most common hereditary colorectal cancer syndrome is hereditary non-polyposis colorectal cancer (HNPCC), also known as Lynch syndrome. Diagnosis of this syndrome is difficult, because of lack of specific diagnostic features...
  17. doi request reprint Nurse endoscopists perform colonoscopies according to the international standard and with high patient satisfaction
    P G van Putten
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Endoscopy 44:1127-32. 2012
    ..Colonoscopy is increasingly performed by nurse endoscopists. We aimed to assess the endoscopic quality and patient experience of these procedures...
  18. pmc Face-to-face vs telephone pre-colonoscopy consultation in colorectal cancer screening; a randomised trial
    E M Stoop
    Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Br J Cancer 107:1051-8. 2012
    ..We hypothesised that a telephone consultation would lead to higher response and participation in CRC screening compared with a face-to-face consultation...
  19. doi request reprint Benchmarking patient experiences in colonoscopy using the Global Rating Scale
    J Sint Nicolaas
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Endoscopy 44:462-72. 2012
    ..The aim of the current study was to evaluate patient experiences of colonoscopy using the GRS in order to compare different departments and to provide benchmarks. The study also evaluated factors associated with patient satisfaction...
  20. doi request reprint High cumulative risk of intussusception in patients with Peutz-Jeghers syndrome: time to update surveillance guidelines?
    M G F van Lier
    Department of Gastroenterology and Hepatology, University Medical Center, Rotterdam, The Netherlands
    Am J Gastroenterol 106:940-5. 2011
    ..We aimed to assess the characteristics, risk, and onset of intussusception in a large cohort of PJS patients to determine whether enteroscopy with polypectomy should be incorporated into surveillance recommendations...
  21. ncbi request reprint Lack of accuracy of the noninvasive Helicobacter pylori stool antigen test in patients with gastroduodenal ulcer bleeding
    M E van Leerdam
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
    Am J Gastroenterol 98:798-801. 2003
    ..The antigen-based stool assay has proven to be accurate in diagnosing Helicobacter pylori infection in dyspeptic patients. We evaluated the H. pylori antigen-based stool assay (HpSA) in patients with peptic ulcer bleeding (PUB)...
  22. ncbi request reprint The use of genetic testing in hereditary colorectal cancer syndromes: genetic testing in HNPCC, (A)FAP and MAP
    D Ramsoekh
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Clin Genet 72:562-7. 2007
    ..Moreover, time trend analysis showed a decline in test rate in HNPCC families. Studies evaluating the reasons for not testing are needed. Furthermore, a better implementation of genetic testing in clinical practice is desirable...
  23. doi request reprint Risk of colorectal carcinoma in post-liver transplant patients: a systematic review and meta-analysis
    J Sint Nicolaas
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Am J Transplant 10:868-76. 2010
    ..However, in contrast to PSC, non-PSC transplants do not need an intensified screening strategy compared to the general population until a prospective study further defines recommendations...
  24. ncbi request reprint Review article: Helicobacter pylori infection in peptic ulcer haemorrhage
    M E van Leerdam
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
    Aliment Pharmacol Ther 16:66-78. 2002
    ..The success of eradication should always be confirmed because of the risk of recurrence of peptic ulcer disease and bleeding in H. pylori-infected patients...
  25. doi request reprint Pitfalls in molecular analysis for mismatch repair deficiency in a family with biallelic pms2 germline mutations
    C H M Leenen
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Clin Genet 80:558-65. 2011
    ..With inconclusive or conflicting results, germline mutation analysis of the MMR genes should be considered after thorough counselling of the patients and/or their relatives...
  26. doi request reprint Quality of life and psychological distress in patients with Peutz-Jeghers syndrome
    M G F van Lier
    Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Clin Genet 78:219-26. 2010
    ..Illness perceptions and female gender were major predictors for this lower QoL. These results may help to recognize PJS patients who might benefit from psychological support...
  27. ncbi request reprint Population screening for colorectal cancer: faeces, endoscopes or X-rays?
    D Ramsoekh
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Cell Oncol 29:185-94. 2007
    ..In Europe, faecal occult blood testing and flexible sigmoidoscopy are currently the most suitable screening modalities for colorectal cancer screening...
  28. ncbi request reprint The role of acid suppressants in upper gastrointestinal ulcer bleeding
    M E van Leerdam
    Department of Gastroenterology and Hepatology, Academic Medical Center, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands
    Best Pract Res Clin Gastroenterol 15:463-75. 2001
    ..Mortality was, however, not reduced. The additional effect of acid-suppressant agents after successful endoscopic therapy is limited to the reduction of re-bleeding and need for surgery, with no effect on mortality...
  29. ncbi request reprint Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000
    M E van Leerdam
    Department of Gastroenterology, Academic Medical Center, Amsterdam, The Netherlands
    Am J Gastroenterol 98:1494-9. 2003
    ..The aim of this study was to examine recent time trends in incidence and outcome of upper GI bleeding...
  30. ncbi request reprint [A man from Surinam with haemorrhagic diarrhoea after long-standing schistosomiasis]
    M E van Leerdam
    afd Interne Geneeskunde, Ikazia Ziekenhuis, Montessoriweg 1, 3083 AN Rotterdam
    Ned Tijdschr Geneeskd 148:1928-30. 2004
    ..The schistosomiasis was thus diagnosed more than 10 years after the last possible exposure to schistosomal cercariae. The patient was treated with a single dose of praziquantel...
  31. doi request reprint Acute gastrointestinal bleeding
    M E van Leerdam
    Best Pract Res Clin Gastroenterol 22:207-8. 2008