C Janneke van der Woude

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi request reprint Chronic inflammation, apoptosis and (pre-)malignant lesions in the gastro-intestinal tract
    C J van der Woude
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands
    Apoptosis 9:123-30. 2004
  2. ncbi request reprint Biologics in Crohn's disease: searching indicators for outcome
    C Janneke van der Woude
    Erasmus MC, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands
    Expert Opin Biol Ther 7:1233-43. 2007
  3. doi request reprint Are we ready for top-down therapy for inflammatory bowel diseases: pro
    C Janneke van der Woude
    Erasmus Medical Center, Department of Gastroenterology and Hepatology, Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands
    Expert Rev Gastroenterol Hepatol 1:243-8. 2007
  4. ncbi request reprint Bleeding - not always a sign of relapse of long-standing colitis
    C J van der Woude
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands
    Endoscopy 39:E121-2. 2007
  5. pmc Expression of apoptosis related proteins during malignant progression in chronic ulcerative colitis
    C J van der Woude
    Departments of Gastroenterology and Hepatology, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Clin Pathol 58:811-4. 2005
  6. pmc Laparoscopic ileocolic resection versus infliximab treatment of distal ileitis in Crohn's disease: a randomized multicenter trial (LIR!C-trial)
    Emma J Eshuis
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
    BMC Surg 8:15. 2008
  7. ncbi request reprint Chromosomal and microsatellite instability of adenocarcinomas and dysplastic lesions (DALM) in ulcerative colitis
    Jolanda M van Dieren
    Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands
    Diagn Mol Pathol 15:216-22. 2006
  8. doi request reprint Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding
    J Jasper Deuring
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre Rotterdam, 3015 CE Rotterdam, The Netherlands
    Biochem J 441:87-93. 2012
  9. doi request reprint IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer
    Yi Li
    Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands
    Carcinogenesis 33:1889-96. 2012
  10. pmc Local immune regulation of mucosal inflammation by tacrolimus
    Jolanda M van Dieren
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, s Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands
    Dig Dis Sci 55:2514-9. 2010

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Chronic inflammation, apoptosis and (pre-)malignant lesions in the gastro-intestinal tract
    C J van der Woude
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands
    Apoptosis 9:123-30. 2004
    ....
  2. ncbi request reprint Biologics in Crohn's disease: searching indicators for outcome
    C Janneke van der Woude
    Erasmus MC, Department of Gastroenterology and Hepatology, Rotterdam, The Netherlands
    Expert Opin Biol Ther 7:1233-43. 2007
    ..This review presents biologics in Crohn's disease focusing on efficacy, steroid sparing, mucosal healing and safety, including immunogenicity...
  3. doi request reprint Are we ready for top-down therapy for inflammatory bowel diseases: pro
    C Janneke van der Woude
    Erasmus Medical Center, Department of Gastroenterology and Hepatology, Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands
    Expert Rev Gastroenterol Hepatol 1:243-8. 2007
    ..Important factors that are relevant for this discussion are quality of life, need for corticosteroids and surgery. This article aims to explore whether we are indeed ready for a top-down approach toward biologics...
  4. ncbi request reprint Bleeding - not always a sign of relapse of long-standing colitis
    C J van der Woude
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands
    Endoscopy 39:E121-2. 2007
  5. pmc Expression of apoptosis related proteins during malignant progression in chronic ulcerative colitis
    C J van der Woude
    Departments of Gastroenterology and Hepatology, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Clin Pathol 58:811-4. 2005
    ..Chronic ulcerative colitis (CUC) is associated with increased risk of developing colon cancer through a dysplasia (intraepithelial neoplasia)-carcinoma sequence...
  6. pmc Laparoscopic ileocolic resection versus infliximab treatment of distal ileitis in Crohn's disease: a randomized multicenter trial (LIR!C-trial)
    Emma J Eshuis
    Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
    BMC Surg 8:15. 2008
    ..The objective of this study is to compare infliximab treatment with laparoscopic ileocolic resection in patients with recurrent Crohn's disease of the distal ileum with respect to quality of life and costs...
  7. ncbi request reprint Chromosomal and microsatellite instability of adenocarcinomas and dysplastic lesions (DALM) in ulcerative colitis
    Jolanda M van Dieren
    Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands
    Diagn Mol Pathol 15:216-22. 2006
    ..Further, we found a low percentage of MSI. Thus, DALM/UCCs display profound chromosomal instability, but this is not associated with concurrent MSI...
  8. doi request reprint Absence of ABCG2-mediated mucosal detoxification in patients with active inflammatory bowel disease is due to impeded protein folding
    J Jasper Deuring
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre Rotterdam, 3015 CE Rotterdam, The Netherlands
    Biochem J 441:87-93. 2012
    ....
  9. doi request reprint IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer
    Yi Li
    Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands
    Carcinogenesis 33:1889-96. 2012
    ..Hence, DNMT1 emerges as a rational target in preventive strategies aimed at counteracting UC-CRC...
  10. pmc Local immune regulation of mucosal inflammation by tacrolimus
    Jolanda M van Dieren
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, s Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands
    Dig Dis Sci 55:2514-9. 2010
    ..Our in vivo studies aimed at evaluating whether local tacrolimus treatment in mice would bring about local immune suppression and to compare colonic and systemic tacrolimus levels after locally and systemically applied tacrolimus...
  11. doi request reprint Inflammatory bowel disease-patients are insufficiently educated about the basic characteristics of their disease and the associated risk of colorectal cancer
    Judith E Baars
    Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Postbus 2040, 3000 CA Rotterdam, The Netherlands
    Dig Liver Dis 42:777-84. 2010
    ..We assessed patients' knowledge of disease and its associated risks/complications, and their perspectives on current recommendations for colectomy when low-grade dysplasia is found...
  12. doi request reprint Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease
    Bindia Jharap
    Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands
    Gut 63:451-7. 2014
    ..We performed a study in pregnant patients with IBD who were using thiopurines, in order to determine the influence of pregnancy on thiopurine metabolism and to assess intrauterine exposure of the fetus to thiopurines...
  13. ncbi request reprint Risk factors of work disability in patients with inflammatory bowel disease--a Dutch nationwide web-based survey: work disability in inflammatory bowel disease
    Mirthe E van der Valk
    Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Crohns Colitis 8:590-7. 2014
    ..Inflammatory bowel disease (IBD) is associated with high costs to society. Few data on the impact of IBD on work disability and potential predictive factors are available...
  14. doi request reprint A short course of corticosteroids prior to surveillance colonoscopy to decrease mucosal inflammation in inflammatory bowel disease patients: results from a randomized controlled trial
    Judith E Baars
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands
    J Crohns Colitis 4:661-8. 2010
    ..This randomized controlled trial assessed the effectiveness of a low dose of corticosteroids prior to surveillance colonoscopy to decrease mucosal inflammation...
  15. pmc Biomarker-based prediction of inflammatory bowel disease-related colorectal cancer: a case-control study
    Monique M Gerrits
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Cell Oncol (Dordr) 34:107-17. 2011
    ..Screening accuracy may increase by using a biomarker-based surveillance strategy...
  16. pmc STAT1, STAT6 and adenosine 3',5'-cyclic monophosphate (cAMP) signaling drive SOCS3 expression in inactive ulcerative colitis
    Yi Li
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, Netherlands
    Mol Med 18:1412-9. 2012
    ..Our results highlight the multifactorial nature of the factors that cause exacerbation in UC...
  17. doi request reprint SOCS3 in immune regulation of inflammatory bowel disease and inflammatory bowel disease-related cancer
    Yi Li
    Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands
    Cytokine Growth Factor Rev 23:127-38. 2012
    ..Finally, we explore how this knowledge may open novel avenues for the rational treatment of IBD and IBD-related cancer...
  18. ncbi request reprint Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease
    J Jasper Deuring
    Department Gastroenterology and Hepatology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Gut 63:1081-91. 2014
    ..Paneth cells are specialised antimicrobial epithelial cells localised to the small-intestinal crypt-base. Here, we investigate whether genomic variations in ATG16L1 affect Paneth cell function...
  19. doi request reprint Disease severity does not affect the interval between IBD diagnosis and the development of CRC: results from two large, Dutch case series
    Erik Mooiweer
    Department of Gastroenterology and Hepatology, University Medical Center Utrecht, The Netherlands
    J Crohns Colitis 6:435-40. 2012
    ..In the present study we aimed to identify characteristics potentially explaining these differences in two cohorts of patients with IBD-related CRC...
  20. doi request reprint Impeded protein folding and function in active inflammatory bowel disease
    J Jasper Deuring
    Erasmus MC University Medical Centre Rotterdam, Department of Gastroenterology and Hepatology, s Gravendijkwal 230, Room L 462, 3015 CE Rotterdam, The Netherlands
    Biochem Soc Trans 39:1107-11. 2011
    ..In the present review, we discuss the possible inflammatory pathways affecting protein folding and eventually leading to IEC malfunction in patients with active IBD...
  21. doi request reprint Local application of tacrolimus in distal colitis: feasible and safe
    Jolanda M van Dieren
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Inflamm Bowel Dis 15:193-8. 2009
    ..However, potential toxicity and systemic (side) effects after oral intake limit its use. We investigated the local applicability and safety of tacrolimus for distal colitis...
  22. doi request reprint Misclassification of dysplasia in patients with inflammatory bowel disease: consequences for progression rates to advanced neoplasia
    Fiona D M van Schaik
    University Medical Center Utrecht, Department of Gastroenterology and Hepatology, Utrecht, The Netherlands
    Inflamm Bowel Dis 17:1108-16. 2011
    ..We studied the progression rate of flat LGD and IND to advanced neoplasia (high-grade dysplasia [HGD] or colorectal cancer [CRC]) before and after histopathological review by a panel of gastrointestinal expert pathologists...
  23. doi request reprint Phenotype of inflammatory bowel disease at diagnosis in the Netherlands: a population-based inception cohort study (the Delta Cohort)
    Veerle J A A Nuij
    Department of Gastroenterology and Hepatology, ErasmusMC, Rotterdam, The Netherlands
    Inflamm Bowel Dis 19:2215-22. 2013
    ..To describe the clinical characteristics of inflammatory bowel disease (IBD) at diagnosis in The Netherlands at the population level in the era of biologics...
  24. doi request reprint Adalimumab combined with ciprofloxacin is superior to adalimumab monotherapy in perianal fistula closure in Crohn's disease: a randomised, double-blind, placebo controlled trial (ADAFI)
    Pieter Dewint
    Department of Gastroenterology and Hepatology, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Gut 63:292-9. 2014
    ..To assess whether a combination of adalimumab and ciprofloxacin is superior to adalimumab alone in the treatment of perianal fistulising Crohn's disease (CD)...
  25. pmc Sex-dimorphic adverse drug reactions to immune suppressive agents in inflammatory bowel disease
    Zuzana Zelinkova
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, NL 3000 CA Rotterdam, The Netherlands
    World J Gastroenterol 18:6967-73. 2012
    ..To analyze sex differences in adverse drug reactions (ADR) to the immune suppressive medication in inflammatory bowel disease (IBD) patients...
  26. doi request reprint Solution focused therapy: a promising new tool in the management of fatigue in Crohn's disease patients psychological interventions for the management of fatigue in Crohn's disease
    Lauran Vogelaar
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands
    J Crohns Colitis 5:585-91. 2011
    ..Crohn's disease patients have a decreased Quality of Life (QoL) which is in part due to extreme fatigue. In a pilot study we prospectively assessed the feasibility and effect of psychological interventions in the management of fatigue...
  27. ncbi request reprint Roles of CD1d-restricted NKT cells in the intestine
    Jolanda M van Dieren
    Laboratory of Pediatrics, Division of Gastroenterology and Nutrition, Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, and Department of Pediatric Gastroenterology, Sophia Children s Hospital, Rotterdam, The Netherlands
    Inflamm Bowel Dis 13:1146-52. 2007
    ..In this article we review the current literature on intestinal NKT cells and their roles in IBD pathogenesis. Specifically, the nomenclature, NKT antigens, and immune mechanisms of NKT cells within the intestinal mucosa are discussed...
  28. doi request reprint Anti-inflammatory actions of phosphatidylinositol
    Jolanda M van Dieren
    Laboratory of Pediatrics, Division of Gastroenterology and Nutrition, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Eur J Immunol 41:1047-57. 2011
    ..These data validate PI as a pluripotent inhibitor that can be applied mucosally as well as systemically. Its compelling functions render PI a promising novel physiological immune suppressant...
  29. doi request reprint New insights into the role of STAT3 in IBD
    Yi Li
    Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands
    Inflamm Bowel Dis 18:1177-83. 2012
    ..As such, the action of STAT3 in IBD is highly context-dependent but always important...
  30. doi request reprint Patients' preferences regarding shared decision-making in the treatment of inflammatory bowel disease: results from a patient-empowerment study
    Judith E Baars
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands j baars erasmusmc nl
    Digestion 81:113-9. 2010
    ..Because data are lacking on the preferences of patients with chronic diseases such as inflammatory bowel disease (IBD), we wanted to assess IBD patients' preferences about being involved in such decisions...
  31. doi request reprint Disease-related expression of the IL6/STAT3/SOCS3 signalling pathway in ulcerative colitis and ulcerative colitis-related carcinogenesis
    Yi Li
    Department of Gastroenterology and Hepatology, Erasmus Medical Centre, Rotterdam, Netherlands
    Gut 59:227-35. 2010
    ..Mouse models have shown that interleukin (IL)6 stimulates survival, proliferation and progression to cancer of intestinal epithelial cells via activation of signal transducers and activators of transcription 3 (STAT3)...
  32. ncbi request reprint Genomic analysis of a case of multifocal adenocarcinoma in ulcerative colitis
    Herman van Dekken
    Department of Pathology, Erasmus Medical Center, Josephine Nefkens Institute, Dr Molewaterplein 50, 3015GE Rotterdam, The Netherlands
    Virchows Arch 449:716-21. 2006
    ..We conclude that these three multifocal tumors must have originated from the same preneoplastic lineage...
  33. doi request reprint Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNFα therapy: results from the COIN study
    Mirthe Emilie van der Valk
    Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Gut 63:72-9. 2014
    ..We aimed to assess the healthcare costs and productivity losses in a large cohort of IBD patients...
  34. doi request reprint Do pregnancy-related changes in the microbiome stimulate innate immunity?
    Sergey R Konstantinov
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, Gravendijkwal 230, NL 3015 CE Rotterdam, The Netherlands
    Trends Mol Med 19:454-9. 2013
    ..As the underlying mechanisms are not well understood, elucidating how pregnancy-related changes in the microbiome influence IBD would be of obvious value for designing rational therapy. ..
  35. pmc Peripheral neutrophil functions and cell signalling in Crohn`s disease
    Rajesh Somasundaram
    Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Rotterdam, The Netherlands
    PLoS ONE 8:e84521. 2013
    ..In toto, these data show a disturbed signal transduction activation and functionality in peripheral blood PMN from patients with quiescent CD, which point toward an intrinsic defect in innate immunity in these patients. ..
  36. doi request reprint Predictors of dose escalation of adalimumab in a prospective cohort of Crohn's disease patients
    E Bultman
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre Rotterdam, The Netherlands
    Aliment Pharmacol Ther 35:335-41. 2012
    ..Adalimumab is effective for the induction and maintenance of remission in Crohn's disease (CD)-patients...
  37. ncbi request reprint Effects of discontinuing anti-tumor necrosis factor therapy during pregnancy on the course of inflammatory bowel disease and neonatal exposure
    Zuzana Zelinkova
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, Netherlands
    Clin Gastroenterol Hepatol 11:318-21. 2013
    ..We assessed the course of inflammatory bowel disease (IBD) among pregnant women who stopped taking anti-tumor necrosis factor (TNF) agents. We also analyzed levels of anti-TNF agents in cord blood samples...
  38. doi request reprint Single-balloon enteroscopy, magnetic resonance enterography, and abdominal US useful for evaluation of small-bowel disease in children with (suspected) Crohn's disease
    Lissy de Ridder
    Department of Pediatric Gastroenterology, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    Gastrointest Endosc 75:87-94. 2012
    ..The usefulness of single-balloon enteroscopy (SBE) has not been evaluated in children with known or suspected Crohn's disease (CD)...
  39. doi request reprint Acute CNS white matter lesions in patients with inflammatory bowel disease
    Lonneke M L de Lau
    Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Inflamm Bowel Dis 15:576-80. 2009
    ..Most previous reports involve cerebral venous thrombosis, central nervous system vasculitis, or peripheral nerve inflammation...
  40. doi request reprint Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk
    Eleonora A M Festen
    Department of Gastroenterology and Hepatology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Am J Gastroenterol 105:395-402. 2010
    ..Genetic susceptibility is known to make a major contribution to the pathogenesis of ulcerative colitis (UC). Recently, three studies, including a genome-wide association study (GWAS), reported novel UC risk loci...
  41. pmc Patient's perspectives important for early anti-tumor necrosis factor treatment in inflammatory bowel disease
    Judith E Baars
    Department of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands
    Digestion 79:30-5. 2009
    ..We assessed the perspectives of patients with inflammatory bowel disease (IBD) concerning the treatment-associated risks/benefits of infliximab...
  42. ncbi request reprint Revisiting the immunomodulators tacrolimus, methotrexate, and mycophenolate mofetil: their mechanisms of action and role in the treatment of IBD
    Jolanda M van Dieren
    Department of Gastroenterology and Hepatology, Division of Gastroenterology and Nutrition, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Inflamm Bowel Dis 12:311-27. 2006
    ..First, this review discusses the potential targets for immunomodulating therapies in IBDs. Second, the immunomodulating mechanisms and effects of the 3 immunomodulators are discussed in relationship to these treatment targets...