Mark K Titulaer

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc A database application for pre-processing, storage and comparison of mass spectra derived from patients and controls
    Mark K Titulaer
    Department of Neurology, Erasmus MC, Rotterdam, The Netherlands
    BMC Bioinformatics 7:403. 2006
  2. pmc A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation
    Mark K Titulaer
    Department of Neurology, Laboratory of Neuro Oncology, Clinical and Cancer Proteomics, Erasmus Medical Center, Dr, Molewaterplein 50, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    BMC Bioinformatics 9:133. 2008
  3. doi request reprint Quantitative matrix-assisted laser desorption ionization-fourier transform ion cyclotron resonance (MALDI-FT-ICR) peptide profiling and identification of multiple-sclerosis-related proteins
    Marcel P Stoop
    Laboratories of Neuro Oncology Clinical and Cancer Proteomics, Department of Neurology, Erasmus University Medical Centre, Rotterdam 3000 DR, The Netherlands
    J Proteome Res 8:1404-14. 2009
  4. pmc Proteomics comparison of cerebrospinal fluid of relapsing remitting and primary progressive multiple sclerosis
    Marcel P Stoop
    Laboratory of Neuro Oncology, Department of Neurology, Erasmus University Medical Centre, Rotterdam, The Netherlands
    PLoS ONE 5:e12442. 2010
  5. ncbi request reprint Identification of glioma neovascularization-related proteins by using MALDI-FTMS and nano-LC fractionation to microdissected tumor vessels
    Dana A N Mustafa
    Department of Pathology, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GD Rotterdam, The Netherlands
    Mol Cell Proteomics 6:1147-57. 2007
  6. doi request reprint Multiple sclerosis-related proteins identified in cerebrospinal fluid by advanced mass spectrometry
    Marcel P Stoop
    Laboratories of Neuro Oncology Clinical and Cancer Proteomics, Department of Neurology, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Proteomics 8:1576-85. 2008
  7. doi request reprint Differential expression of protease activity in serum samples of prostate carcinoma patients with metastases
    Lennard J M Dekker
    Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Proteomics 10:2348-58. 2010
  8. doi request reprint Proteomic analysis of human osteoblastic cells: relevant proteins and functional categories for differentiation
    Rodrigo D A M Alves
    Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Proteome Res 9:4688-700. 2010
  9. pmc Label-free peptide profiling of Orbitrap™ full mass spectra
    Mark K Titulaer
    Laboratory of Neuro Oncology and Clinical and Cancer Proteomics, Department of Neurology, Erasmus University Medical Center, Dr, Molewaterplein 50, P, O, Box 2040, 3000 CA Rotterdam, The Netherlands
    BMC Res Notes 4:21. 2011
  10. doi request reprint Proteomic analysis of naphthalene-induced airway epithelial injury and repair in a cystic fibrosis mouse model
    Isabel M Carvalho-Oliveira
    Department of Cell Biology, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Proteome Res 8:3606-16. 2009

Collaborators

Detail Information

Publications10

  1. pmc A database application for pre-processing, storage and comparison of mass spectra derived from patients and controls
    Mark K Titulaer
    Department of Neurology, Erasmus MC, Rotterdam, The Netherlands
    BMC Bioinformatics 7:403. 2006
    ....
  2. pmc A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation
    Mark K Titulaer
    Department of Neurology, Laboratory of Neuro Oncology, Clinical and Cancer Proteomics, Erasmus Medical Center, Dr, Molewaterplein 50, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    BMC Bioinformatics 9:133. 2008
    ..The software application is tested by searching angiogenesis related proteins in glioma by comparing laser capture micro dissected- and enzymatic by trypsin digested tissue sections...
  3. doi request reprint Quantitative matrix-assisted laser desorption ionization-fourier transform ion cyclotron resonance (MALDI-FT-ICR) peptide profiling and identification of multiple-sclerosis-related proteins
    Marcel P Stoop
    Laboratories of Neuro Oncology Clinical and Cancer Proteomics, Department of Neurology, Erasmus University Medical Centre, Rotterdam 3000 DR, The Netherlands
    J Proteome Res 8:1404-14. 2009
    ..Application on a set of 163 cerebrospinal fluid (CSF) samples showed significantly differential abundant peptides, which were subsequently identified into proteins (e.g., chromogranin A, clusterin, and complement C3)...
  4. pmc Proteomics comparison of cerebrospinal fluid of relapsing remitting and primary progressive multiple sclerosis
    Marcel P Stoop
    Laboratory of Neuro Oncology, Department of Neurology, Erasmus University Medical Centre, Rotterdam, The Netherlands
    PLoS ONE 5:e12442. 2010
    ..Proteomics analysis of cerebrospinal fluid (CSF) has detected a number of proteins that were elevated in MScl patients. Here we specifically aimed to differentiate between the PP and RR subtypes of MScl by comparing CSF proteins...
  5. ncbi request reprint Identification of glioma neovascularization-related proteins by using MALDI-FTMS and nano-LC fractionation to microdissected tumor vessels
    Dana A N Mustafa
    Department of Pathology, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GD Rotterdam, The Netherlands
    Mol Cell Proteomics 6:1147-57. 2007
    ..This work proves that gel-free mass spectrometric techniques can be used on relatively small numbers of cells generated by microdissection procedures to successfully identify differentially expressed proteins...
  6. doi request reprint Multiple sclerosis-related proteins identified in cerebrospinal fluid by advanced mass spectrometry
    Marcel P Stoop
    Laboratories of Neuro Oncology Clinical and Cancer Proteomics, Department of Neurology, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Proteomics 8:1576-85. 2008
    ..CSF chromogranin A levels were confirmed to be significantly elevated in the MScl group using an ELISA...
  7. doi request reprint Differential expression of protease activity in serum samples of prostate carcinoma patients with metastases
    Lennard J M Dekker
    Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Proteomics 10:2348-58. 2010
    ..Importantly, the observed prostate carcinoma-related inhibition of the proteolysis was reproduced ex vivo using synthetic peptides...
  8. doi request reprint Proteomic analysis of human osteoblastic cells: relevant proteins and functional categories for differentiation
    Rodrigo D A M Alves
    Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Proteome Res 9:4688-700. 2010
    ..Taken together, this study increases our understanding of the proteomics changes that accompany osteoblast differentiation and may permit the discovery of novel modulators of bone formation...
  9. pmc Label-free peptide profiling of Orbitrap™ full mass spectra
    Mark K Titulaer
    Laboratory of Neuro Oncology and Clinical and Cancer Proteomics, Department of Neurology, Erasmus University Medical Center, Dr, Molewaterplein 50, P, O, Box 2040, 3000 CA Rotterdam, The Netherlands
    BMC Res Notes 4:21. 2011
    ..abstract:..
  10. doi request reprint Proteomic analysis of naphthalene-induced airway epithelial injury and repair in a cystic fibrosis mouse model
    Isabel M Carvalho-Oliveira
    Department of Cell Biology, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Proteome Res 8:3606-16. 2009
    ..Further, the results suggest the involvement of prostaglandin and retinoic acid metabolism in the abnormal responses of CF mutant mice to injury...