B H C Stricker

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc Reproductive aging-associated common genetic variants and the risk of breast cancer
    Chunyan He
    Department of Public Health, Indiana University School of Medicine, 980 West Walnut Street, R3 C241, Indianapolis, IN 46202, USA
    Breast Cancer Res 14:R54. 2012
  2. pmc Improving lung cancer survival; time to move on
    Marlies E Heuvers
    Department of Respiratory Diseases and Tuberculosis, Erasmus Medical University Center, Rotterdam, The Netherlands
    BMC Pulm Med 12:77. 2012
  3. doi request reprint Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the Rotterdam Study
    Lies Lahousse
    Department of Respiratory Medicine, Ghent University, Ghent University Hospital, Belgium
    Am J Respir Crit Care Med 187:58-64. 2013
  4. doi request reprint Statin use is associated with reduced incidence and progression of knee osteoarthritis in the Rotterdam study
    S Clockaerts
    Department of Orthopaedics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Ann Rheum Dis 71:642-7. 2012
  5. pmc OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users
    Matthijs L Becker
    Department of Epidemiology, Erasmus MC, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Neurogenetics 12:79-82. 2011
  6. pmc The association of serum testosterone levels and ventricular repolarization
    Charlotte van Noord
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Epidemiol 25:21-8. 2010
  7. pmc Risk of cancer in patients on insulin glargine and other insulin analogues in comparison with those on human insulin: results from a large population-based follow-up study
    R Ruiter
    Department of Epidemiology, Erasmus MC, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Diabetologia 55:51-62. 2012
  8. pmc Lower risk of cancer in patients on metformin in comparison with those on sulfonylurea derivatives: results from a large population-based follow-up study
    Rikje Ruiter
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Diabetes Care 35:119-24. 2012
  9. ncbi request reprint Protective effect of NSAIDs on cancer and influence of COX-2 C(-765G) genotype
    C Siemes
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Rotterdam, The Netherlands
    Curr Cancer Drug Targets 8:753-64. 2008
  10. ncbi request reprint [Plea for the retention of the Dutch National Medical Registration (LMR) to provide reliable information regarding public health and healthcare]
    B H Ch Stricker
    Erasmus MC, afd Epidemiologie en Biostatistiek, Postbus 1738, 3000 DR Rotterdam
    Ned Tijdschr Geneeskd 150:1916-7. 2006

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. pmc Reproductive aging-associated common genetic variants and the risk of breast cancer
    Chunyan He
    Department of Public Health, Indiana University School of Medicine, 980 West Walnut Street, R3 C241, Indianapolis, IN 46202, USA
    Breast Cancer Res 14:R54. 2012
    ..Recent genome-wide association studies have identified several novel genetic loci associated with these two traits. However, the association between these loci and breast cancer risk is unknown...
  2. pmc Improving lung cancer survival; time to move on
    Marlies E Heuvers
    Department of Respiratory Diseases and Tuberculosis, Erasmus Medical University Center, Rotterdam, The Netherlands
    BMC Pulm Med 12:77. 2012
    ..During the past decades, numerous efforts have been made to decrease the death rate among lung cancer patients. Nonetheless, the improvement in long-term survival has been limited and lung cancer is still a devastating disease...
  3. doi request reprint Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the Rotterdam Study
    Lies Lahousse
    Department of Respiratory Medicine, Ghent University, Ghent University Hospital, Belgium
    Am J Respir Crit Care Med 187:58-64. 2013
    ..Even though vulnerable carotid artery plaque components, such as intraplaque hemorrhage and lipid core, place persons at high risk for ischemic events, the plaque composition in patients with COPD has never been explored...
  4. doi request reprint Statin use is associated with reduced incidence and progression of knee osteoarthritis in the Rotterdam study
    S Clockaerts
    Department of Orthopaedics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Ann Rheum Dis 71:642-7. 2012
    ..As statins are able to modulate many of these processes, this study examines whether statin use is associated with a decreased incidence and/or progression of osteoarthritis...
  5. pmc OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users
    Matthijs L Becker
    Department of Epidemiology, Erasmus MC, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Neurogenetics 12:79-82. 2011
    ..34 defined daily dose higher (95% CI 0.064, 0.62; p=0.017). The mortality ratio after start of levodopa therapy was 1.47 times higher (95% CI 1.01, 2.13; p=0.045)...
  6. pmc The association of serum testosterone levels and ventricular repolarization
    Charlotte van Noord
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Epidemiol 25:21-8. 2010
    ..Lower QTc intervals in men with higher serum testosterone levels could be due to the association of serum testosterone with prolongation of the RR interval...
  7. pmc Risk of cancer in patients on insulin glargine and other insulin analogues in comparison with those on human insulin: results from a large population-based follow-up study
    R Ruiter
    Department of Epidemiology, Erasmus MC, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Diabetologia 55:51-62. 2012
    ..We investigated whether insulin glargine (A21Gly,B31Arg,B32Arg human insulin) is associated with an increased risk of cancer in a large population-based cohort study...
  8. pmc Lower risk of cancer in patients on metformin in comparison with those on sulfonylurea derivatives: results from a large population-based follow-up study
    Rikje Ruiter
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Diabetes Care 35:119-24. 2012
    ....
  9. ncbi request reprint Protective effect of NSAIDs on cancer and influence of COX-2 C(-765G) genotype
    C Siemes
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Rotterdam, The Netherlands
    Curr Cancer Drug Targets 8:753-64. 2008
    ..The aim of this study was to explore the role of cumulative NSAID use on four common non-skin related cancers and modification by COX-2 G(-765)C genotype...
  10. ncbi request reprint [Plea for the retention of the Dutch National Medical Registration (LMR) to provide reliable information regarding public health and healthcare]
    B H Ch Stricker
    Erasmus MC, afd Epidemiologie en Biostatistiek, Postbus 1738, 3000 DR Rotterdam
    Ned Tijdschr Geneeskd 150:1916-7. 2006
    ..Therefore, the LMR system cannot be missed...
  11. pmc Detection, verification, and quantification of adverse drug reactions
    Bruno H Ch Stricker
    Pharmacoepidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam
    BMJ 329:44-7. 2004
  12. pmc Analysis of individual drug use as a time-varying determinant of exposure in prospective population-based cohort studies
    B H Ch Stricker
    Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 25:245-51. 2010
    ..However, such estimates may be biased in the presence of time-dependent confounders which are themselves affected by prior exposure...
  13. ncbi request reprint Generalizing lung-cancer screening results
    Marlies E Heuvers
    Erasmus Medical Center, Rotterdam, The Netherlands
    N Engl J Med 366:192-3. 2012
    ..Others at some risk were excluded; whether the 20% reduction in mortality seen in the NLST will transfer to other risk groups is unclear...
  14. doi request reprint Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus
    M L Becker
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Pharmacogenomics J 9:242-7. 2009
    ..09-0.47, P=0.005). After Bonferroni correction, the P-value was 0.050. To conclude, genetic variation at rs622342 in the SLC22A1 gene was associated with the glucose-lowering effect of metformin in patients with diabetes mellitus...
  15. doi request reprint Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study
    M D M Haag
    Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 80:13-7. 2009
    ..Prospective studies have provided inconsistent evidence. Moreover, it is unclear whether the association differs for lipophilic statins, those that could more easily pass the blood-brain barrier and hydrophilic statins...
  16. doi request reprint Renin-angiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/deletion polymorphism, and cancer: the Rotterdam Study
    Ronald van der Knaap
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, Netherlands
    Cancer 112:748-57. 2008
    ....
  17. pmc Heart failure and the risk of stroke: the Rotterdam Study
    V P Alberts
    Department of Epidemiology, Erasmus MC University Medical Center, Dr Molewaterplein 50, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Eur J Epidemiol 25:807-12. 2010
    ..In conclusion, the risk of ischemic stroke is strongly increased shortly after the diagnosis of heart failure but returns to normal within 6 months after onset of heart failure...
  18. doi request reprint BclI glucocorticoid receptor polymorphism and smoking in the general population
    Satu J Siiskonen
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Addict Biol 14:349-55. 2009
    ..Furthermore, the BclI glucocorticoid receptor polymorphism did not predict the incidence of smoking cessation in the general elderly population...
  19. pmc A common NOS1AP genetic polymorphism is associated with increased cardiovascular mortality in users of dihydropyridine calcium channel blockers
    Matthijs L Becker
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Br J Clin Pharmacol 67:61-7. 2009
    ..The aim was to investigate whether this polymorphism is associated with cardiovascular mortality in users of CCBs...
  20. ncbi request reprint C-reactive protein levels, variation in the C-reactive protein gene, and cancer risk: the Rotterdam Study
    Claire Siemes
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Clin Oncol 24:5216-22. 2006
    ..The aim of this study was to examine whether C-reactive protein (CRP) levels and CRP gene variations were associated with an altered risk of colorectal, lung, breast, or prostate cancer...
  21. ncbi request reprint Drug-gene interactions between genetic polymorphisms and antihypertensive therapy
    Hedi Schelleman
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Drugs 64:1801-16. 2004
    ..Unfortunately, the quality of these studies is quite variable. Given the methodological problems, the results from the candidate gene studies are still inconclusive and further research is necessary...
  22. doi request reprint Association between the CYP2D6*4 polymorphism and depression or anxiety in the elderly
    Monique J Bijl
    Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Pharmacogenomics 10:541-7. 2009
    ..Relative to extensive metabolizers, these poor metabolizers may have lower baseline serotonin concentrations in various brain regions, and may be more prone to depression or anxiety...
  23. pmc Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants
    Monique J Bijl
    Department of Epidemiology and Biostatistics, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Br J Clin Pharmacol 65:558-64. 2008
    ..Reduced enzyme activity potentially leads to increased toxicity of antidepressants, but the relevance of genotyping for clinical practice is unclear. Most clinical studies suffer from small numbers of patients...
  24. doi request reprint Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study
    Claire Siemes
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Rotterdam, The Netherlands
    Steroids 75:1024-32. 2010
    ..To study if polymorphisms in genes encoding for CYP3A enzymes, that play a role in steroid hormone metabolism, affect steroid hormone serum levels and prostate cancer incidence or mortality...
  25. pmc The Rotterdam Study: 2010 objectives and design update
    Albert Hofman
    Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam The Netherlands
    Eur J Epidemiol 24:553-72. 2009
    ..epib.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods...
  26. doi request reprint The CYP2D6*4 polymorphism affects breast cancer survival in tamoxifen users
    Monique J Bijl
    Department of Epidemiology, Erasmus MC, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Breast Cancer Res Treat 118:125-30. 2009
    ..The risk of breast cancer mortality is increased in tamoxifen users with decreased CYP2D6 activity, consistent with the model in which endoxifen formation is dependent on CYP2D6 activity...
  27. ncbi request reprint Antihypertensive medication and the risk of acute pancreatitis: the European case-control study on drug-induced acute pancreatitis (EDIP)
    Ingo A Eland
    Department of Internal Medicine, Pharmacoepidemiology Unit, Erasmus MC, Rotterdam, The Netherlands
    Scand J Gastroenterol 41:1484-90. 2006
    ..We quantified the risk of acute pancreatitis associated with the use of antihypertensive medication in the European study on drug-induced acute pancreatitis (EDIP)...
  28. ncbi request reprint Drug-induced urinary retention: incidence, management and prevention
    Katia M C Verhamme
    Pharmacoepidemiology Unit, Department of Medical Informatics and Epidemiology and Biostatistics, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Drug Saf 31:373-88. 2008
    ..This article reviews the literature on drug-induced urinary retention and focuses on its incidence, the different classes of drugs that have been associated with it, and options for its management and prevention...
  29. pmc The Rotterdam Study: objectives and design update
    Albert Hofman
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Epidemiol 22:819-29. 2007
    ..epib.nl/rotterdamstudy). This article gives the reasons for the study and its design. It also presents a summary of the major findings and an update of the objectives and methods...
  30. doi request reprint Calcium channel blockers, NOS1AP, and heart-rate-corrected QT prolongation
    Charlotte van Noord
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Pharmacogenet Genomics 19:260-6. 2009
    ..To study whether NOS1AP single nucleotide polymorphisms (SNPs), rs10494366 T>G and rs10918594 C>G, modify the heart-rate-corrected QT (QTc) prolonging effect of calcium channel blockers...
  31. doi request reprint Duration of antihypertensive drug use and risk of dementia: A prospective cohort study
    M D M Haag
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 72:1727-34. 2009
    ..Duration of follow-up was limited and relied mainly on baseline drug exposure data without information on duration of use. We investigated the association between the duration of antihypertensive use and risk of dementia...
  32. doi request reprint Common ATP-binding cassette B1 variants are associated with increased digoxin serum concentration
    Albert Jan L H J Aarnoudse
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands
    Pharmacogenet Genomics 18:299-305. 2008
    ..The goal of this study was to establish ABCB1 genotype effect on digoxin blood concentrations in a large cohort of chronic digoxin users in a general Dutch European population...
  33. doi request reprint Common variation in the NOS1AP gene is associated with reduced glucose-lowering effect and with increased mortality in users of sulfonylurea
    Matthijs L Becker
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Pharmacogenet Genomics 18:591-7. 2008
    ..As sulfonylurea stimulate insulin secretion by an increased influx of Ca, we hypothesized that this polymorphism is associated with the glucose-lowering effect and mortality risk in sulfonylurea users...
  34. ncbi request reprint Mortality in patients with hypertension on angiotensin-I converting enzyme (ACE)-inhibitor treatment is influenced by the ACE insertion/deletion polymorphism
    Gysèle S Bleumink
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Pharmacogenet Genomics 15:75-81. 2005
    ..We studied the possible interaction between ACE-inhibitor therapy in patients with hypertension and the ACE I/D polymorphism in incident heart failure and death...
  35. ncbi request reprint Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study)
    Gysèle S Bleumink
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 94:384-6. 2004
    ....
  36. doi request reprint Serum glucose and insulin are associated with QTc and RR intervals in nondiabetic elderly
    Charlotte van Noord
    Department of Epidemiology, Internal Medicine Medical Informatics, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
    Eur J Endocrinol 162:241-8. 2010
    ....
  37. ncbi request reprint Apolipoprotein E epsilon4 allele is associated with left ventricular systolic dysfunction
    Gysèle S Bleumink
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Am Heart J 147:685-9. 2004
    ..We investigated the association between APOE genotypes and left ventricular dysfunction in a population of community-dwelling elderly subjects...
  38. ncbi request reprint Mefloquine increases the risk of serious psychiatric events during travel abroad: a nationwide case-control study in the Netherlands
    Melanie M van Riemsdijk
    Pharmacoepidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Clin Psychiatry 66:199-204. 2005
    ..Several risk factors have been proposed for such events, one of these being use of mefloquine. We investigated the risk of psychiatric events during use of mefloquine...
  39. ncbi request reprint Lipoprotein-associated phospholipase A2 activity and risk of heart failure: The Rotterdam study
    Laura C van Vark
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Eur Heart J 27:2346-52. 2006
    ..Lipoprotein-associated phospholipase A2 (Lp-PLA2) has pro-inflammatory properties. We investigated whether Lp-PLA2 activity is associated with heart failure...
  40. ncbi request reprint Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam Study
    M Reijman
    Department of Orthopedics, Erasmus MC, Rotterdam, The Netherlands
    Arthritis Rheum 52:3137-42. 2005
    ..To investigate the influence of the use of various types of nonsteroidal antiinflammatory drugs (NSAIDs) on progression of osteoarthritis (OA) of the hip and knee...
  41. pmc Determinants of chronic benzodiazepine use in the elderly: a longitudinal study
    Hendrika J Luijendijk
    Erasmus Medical Centre, Department of Epidemiology and Biostatistics, Rotterdam, The Netherlands
    Br J Clin Pharmacol 65:593-9. 2008
    ..When users were re-examined some years later, chronic somatic disease, pain and stress seemed to contribute to the continuation of benzodiazepine use...
  42. ncbi request reprint The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9
    Loes E Visser
    Department of Epidemiology, Erasmus MC, Rotterdam, Inspectorate for Health Care, The Hague, The Netherlands
    Pharmacogenet Genomics 17:473-9. 2007
    ..The aim of the present follow-up study was to investigate whether the enzyme activity of the human cytochrome P450 (CYP) 2C9 isoenzyme is associated with myocardial infarction...
  43. ncbi request reprint Patients with an ApoE epsilon4 allele require lower doses of coumarin anticoagulants
    Loes E Visser
    Pharmacoepidemiology Unit, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    Pharmacogenet Genomics 15:69-74. 2005
    ..Therefore, we investigated whether this common genetic polymorphism influenced dose requirements and effects of coumarin anticoagulants...
  44. ncbi request reprint Overanticoagulation associated with combined use of antibacterial drugs and acenocoumarol or phenprocoumon anticoagulants
    Loes E Visser
    Pharmacoepidemiology Unit, Department of Internal Medicine, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Thromb Haemost 88:705-10. 2002
    ..Despite the fact that these drugs are frequently prescribed concurrently, there is little quantitative information on the risks of such complications...
  45. ncbi request reprint The cholesteryl ester transfer protein I405V polymorphism is associated with increased high-density lipoprotein levels and decreased risk of myocardial infarction: the Rotterdam Study
    Aaron Isaacs
    Genetic Epidemiology Unit, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Cardiovasc Prev Rehabil 14:419-21. 2007
    ..The effect of the cholesteryl ester transfer protein (CETP) I405V polymorphism on lipid levels, atherosclerosis and myocardial infarction (MI) was examined in 6421 participants from the Rotterdam Study...
  46. doi request reprint Association between calcium channel blockers and gingival hyperplasia
    Gaganpreet Kaur
    Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Clin Periodontol 37:625-30. 2010
    ..To study the effect of the dose and type of calcium channel blockers (CCBs) on the risk of gingival hyperplasia and to quantify this association...
  47. ncbi request reprint Epistatic effect of cholesteryl ester transfer protein and hepatic lipase on serum high-density lipoprotein cholesterol levels
    Aaron Isaacs
    Genetic Epidemiology Unit, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
    J Clin Endocrinol Metab 92:2680-7. 2007
    ..The objectives of the current study were to characterize the effect of the hepatic lipase variant, and its interaction with the CETP variant, in terms of cholesterol levels, atherosclerosis, and risk of myocardial infarction (MI)...
  48. ncbi request reprint The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon
    Loes E Visser
    Department of Internal Medicine, Erasmus MC, 3000 DR Rotterdam, The Netherlands
    Thromb Haemost 92:61-6. 2004
    ....
  49. ncbi request reprint Prolonged QTc interval and risk of sudden cardiac death in a population of older adults
    Sabine M J M Straus
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    J Am Coll Cardiol 47:362-7. 2006
    ..This study sought to investigate whether prolongation of the heart rate-corrected QT (QTc) interval is a risk factor for sudden cardiac death in the general population...
  50. pmc Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study
    Matthijs L Becker
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Diabetes 58:745-9. 2009
    ..We studied the effect of single nucleotide polymorphisms (SNPs) in the SLC47A1 gene on the A1C-lowering effect of metformin...
  51. ncbi request reprint Angiotensinogen M235T polymorphism and the risk of myocardial infarction and stroke among hypertensive patients on ACE-inhibitors or beta-blockers
    Hedi Schelleman
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Eur J Hum Genet 15:478-84. 2007
    ..ACE-inhibitor users with at least one copy of the 235T-allele of the AGT gene might have an increased risk of MI and stroke...
  52. doi request reprint Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy
    Matthijs L Becker
    Department of Epidemiology, Erasmus MC, 3000 CA Rotterdam, The Netherlands
    Pharmacoepidemiol Drug Saf 19:75-81. 2010
    ..These events may indicate that statin plasma levels were too high and resulted in an adverse drug reaction or a too strong reduction in cholesterol level...
  53. ncbi request reprint ApoE gene polymorphisms, BMD, and fracture risk in elderly men and women: the Rotterdam study
    Mariette W C J Schoofs
    Department of Internal Medicine, Erasmus Medical Center, Rotterdam 300 DR, The Netherlands
    J Bone Miner Res 19:1490-6. 2004
    ..We did not observe an association between the ApoE polymorphism and osteoporosis in this study, which is thus far the largest study on ApoE and osteoporosis...
  54. ncbi request reprint Unlicensed and off-label drug use in a paediatric ward of a general hospital in the Netherlands
    G W 't Jong
    Pharmacoepidemiology Unit, Department of Internal Medicine, Epidemiology and Biostatistics, Erasmus Medical Centre Rotterdam, The Netherlands
    Eur J Clin Pharmacol 58:293-7. 2002
    ..We determined the extent and nature of use of unlicensed drugs and off-label prescriptions in children in a general hospital in the Netherlands...
  55. pmc Population-based studies of antithyroid drugs and sudden cardiac death
    Charlotte van Noord
    Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Br J Clin Pharmacol 68:447-54. 2009
    ..The aim was to investigate whether use of antithyroid drugs (as a direct cause or as an indicator of poorly controlled hyperthyroidism) is associated with an increased risk of SCD...
  56. doi request reprint Common genetic variation in the ABCB1 gene is associated with the cholesterol-lowering effect of simvastatin in males
    Matthijs L Becker
    Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Pharmacogenomics 10:1743-51. 2009
    ....
  57. doi request reprint Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response
    Matthijs L Becker
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Pharmacogenet Genomics 20:38-44. 2010
    ..In this study, we assessed whether there exists an interaction between these two polymorphisms...
  58. doi request reprint Genetic variance in CYP2C8 and increased risk of myocardial infarction
    Eline M Rodenburg
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Pharmacogenet Genomics 20:426-34. 2010
    ..CYP2C9 polymorphisms have been associated with an increased risk of MI. As CYP2C8 is genetically linked to CYP2C9 and on account of its role in EET production, we hypothesized that CYP2C8 polymorphisms are associated with the risk of MI...
  59. ncbi request reprint Increasing exposure to drug-drug interactions between 1992 and 2005 in people aged > or = 55 years
    Matthijs L Becker
    Pharmaco epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Drugs Aging 25:145-52. 2008
    ..Drug-drug interactions (DDIs) are responsible for a variety of adverse reactions, particularly in an elderly population...
  60. ncbi request reprint Risk factors for urological symptoms in a cohort of users of the HIV protease inhibitor indinavir sulfate: the ATHENA cohort
    Jeanne P Dieleman
    Pharmaco epidemiology Unit, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
    Arch Intern Med 162:1493-501. 2002
    ..Nephrolithiasis is a well-known complication of indinavir treatment and may result in urological symptoms ranging from renal colic to renal insufficiency...
  61. ncbi request reprint Adverse drug reaction-related hospitalisations: a nationwide study in The Netherlands
    Cornelis S van der Hooft
    Pharmaco epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Drug Saf 29:161-8. 2006
    ..The incidence of adverse drug reaction (ADR)-related hospitalisations has usually been assessed within hospitals. Because of the variability in results and methodology, it is difficult to extrapolate these results to a national level...
  62. ncbi request reprint Drug-gene interaction between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and antihypertensive therapy
    Hedi Schelleman
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, Netherlands
    Ann Pharmacother 40:212-8. 2006
    ..There are some indications that the angiotensin-converting enzyme (ACE) gene modifies the response to antihypertensive drugs, but the results have been inconclusive...
  63. pmc Inappropriate drug prescribing in older adults: the updated 2002 Beers criteria--a population-based cohort study
    Cornelis S van der Hooft
    Pharmaco epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Br J Clin Pharmacol 60:137-44. 2005
    ..Several studies have been performed to estimate the prevalence of inappropriate drug prescribing based on these criteria. In 2002, the criteria were updated...
  64. ncbi request reprint Allelic variants of cytochrome P450 2C9 modify the interaction between nonsteroidal anti-inflammatory drugs and coumarin anticoagulants
    Loes E Visser
    Pharmacoepidemiology Unit, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    Clin Pharmacol Ther 77:479-85. 2005
    ..We investigated whether NSAIDs were associated with overanticoagulation during therapy with coumarins and evaluated the effect of the CYP2C9 polymorphisms on this potential interaction...
  65. ncbi request reprint Angiotensin converting enzyme insertion/deletion polymorphism and the risk of heart failure in hypertensive subjects
    Anna F C Schut
    Genetic Epidemiology Unit, Department of Epidemiology, Eramus Medical Centre Rotterdam, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Eur Heart J 25:2143-8. 2004
    ..We assessed the relation between the ACE I/D polymorphism and the risk of incident heart failure in normotensive and hypertensive subjects...
  66. ncbi request reprint The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon
    Loes E Visser
    Pharmacoepidemiology Unit, Department of Internal Medicine, Easmus MC, Rotterdam, The Netherlands
    Pharmacogenetics 14:27-33. 2004
    ..Phenprocoumon appears to be a clinically useful alternative in patients carrying the CYP2C9*2 and *3 alleles...
  67. pmc Marketing in the lay media and prescriptions of terbinafine in primary care: Dutch cohort study
    Geert W 't Jong
    Department of Medical Informatics, Erasmus University Medical Center, PO Box 1738, 3000 DR Rotterdam, Netherlands
    BMJ 328:931. 2004
  68. ncbi request reprint Thiazide diuretics and the risk for hip fracture
    Mariette W C J Schoofs
    Erasmus MC, Rotterdam, The Netherlands
    Ann Intern Med 139:476-82. 2003
    ..Thiazides have been associated with reduced age-related bone loss by decreasing urinary calcium excretion...
  69. ncbi request reprint Increased risk of achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids
    Paul D van der Linden
    Pharmacoepidemiology Unit, Department of Epidemiology and Biostatistics and Internal Medicine, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands
    Arch Intern Med 163:1801-7. 2003
    ..In several case reports, the occurrence of Achilles tendon rupture has been attributed to the use of quinolones, but the epidemiologic evidence for this association is scanty...
  70. ncbi request reprint Corticosteroids and the risk of atrial fibrillation
    Cornelis S van der Hooft
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands
    Arch Intern Med 166:1016-20. 2006
    ..High-dose (pulse) corticosteroid therapy has been associated with the development of atrial fibrillation. This association, however, is mainly based on case reports...
  71. ncbi request reprint C-reactive protein and risk of heart failure. The Rotterdam Study
    Isabella Kardys
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Am Heart J 152:514-20. 2006
    ..This study was designed to investigate the association between serum CRP levels, as determined by high-sensitivity assay, and the occurrence of heart failure...
  72. ncbi request reprint Age- and gender-specific incidence of hospitalisation for digoxin intoxication
    Adrianus L H J Aarnoudse
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Drug Saf 30:431-6. 2007
    ..Recent literature suggests that women are at higher risk of digoxin toxicity...
  73. ncbi request reprint Antihypertensive treatment is associated with improved left ventricular geometry: the Rotterdam Study
    Gysèle S Bleumink
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands
    Pharmacoepidemiol Drug Saf 13:703-9. 2004
    ..Left ventricular hypertrophy (LVH) increases the risk of cardiovascular disease. We evaluated the association between antihypertensive therapy and echocardiographically determined LVH...
  74. ncbi request reprint Discontinuation of beta-blockers and the risk of myocardial infarction in the elderly
    Martina Teichert
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Drug Saf 30:541-9. 2007
    ..As beta-blockers differ in their pharmacokinetic and pharmacodynamic properties, this risk of discontinuation might also differ between subgroups of beta-blockers...
  75. ncbi request reprint MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine
    Albert L H J Aarnoudse
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Clin Pharmacol Ther 80:367-74. 2006
    ..We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein...
  76. ncbi request reprint Association of nonsteroidal anti-inflammatory drugs with first occurrence of heart failure and with relapsing heart failure: the Rotterdam Study
    Johan Feenstra
    Pharmacoepidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, 3000 DR Rotterdam, The Netherlands
    Arch Intern Med 162:265-70. 2002
    ..It is likely, however, that NSAIDs precipitate a relapse but are less likely to induce a first occurrence of (incident) heart failure...
  77. doi request reprint Non-cardiovascular drugs that inhibit hERG-encoded potassium channels and risk of sudden cardiac death
    Charlotte van Noord
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Heart 97:215-20. 2011
    ..This study assessed whether non-cardiovascular hERG channel blockers are associated with an increased risk of sudden cardiac death (SCD) and whether hERG-channel-inhibiting capacity is an indicator of the risk of SCD...
  78. doi request reprint Effect of short-term NSAID use on echocardiographic parameters in elderly people: a population-based cohort study
    Karen Eline van den Hondel
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Heart 97:540-3. 2011
    ..The association between recent start of NSAIDs in elderly people and echocardiographic parameters was investigated...
  79. ncbi request reprint Cholesterol and age-related macular degeneration: is there a link?
    Redmer van Leeuwen
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Ophthalmol 137:750-2. 2004
    ..To examine the relation among serum cholesterol, apolipoprotein E genotype (APOE), and the risk of early and late age-related macular degeneration (AMD)...
  80. doi request reprint Selective serotonin reuptake inhibiting antidepressants are associated with an increased risk of nonvertebral fractures
    Gijsbertus Ziere
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    J Clin Psychopharmacol 28:411-7. 2008
    ..Exposure to antidepressants is associated with an increased risk of falls and fractures, but most previous studies incriminate tricyclic antidepressants (TCAs) rather than selective serotonin reuptake inhibitors (SSRIs)...
  81. ncbi request reprint Misclassification of exposure is high when interview data on drug use are used as a proxy measure of chronic drug use during follow-up
    Annette B Beiderbeck
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands
    J Clin Epidemiol 57:973-7. 2004
    ..We investigated the magnitude and direction of exposure misclassification by comparing interview data at baseline with prospectively gathered pharmacy data...
  82. ncbi request reprint Prescription medications associated with a decreased risk of non-Hodgkin's lymphoma
    Annette B Beiderbeck
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands
    Am J Epidemiol 157:510-6. 2003
    ..40 (95% confidence interval: 0.22, 0.71). Results support an inverse association between occurrence of non-Hodgkin's lymphoma and use of H(2) blockers and analgesics among women, and they warrant confirmation in larger studies...
  83. ncbi request reprint No increased risk of non-Hodgkin's lymphoma with steroids, estrogens and psychotropics (Netherlands)
    Annette B Beiderbeck
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands
    Cancer Causes Control 14:639-44. 2003
    ..The objective of this case-control study with complete pharmacy records was to investigate whether these results could be reproduced...
  84. pmc Unlicensed and off label prescription of drugs to children: population based cohort study
    Geert W 't Jong
    Department of Paediatrics, Sophia Children s Hospital, Erasmus Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, Netherlands
    BMJ 324:1313-4. 2002
  85. ncbi request reprint Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study
    Jan Heeringa
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Eur Heart J 27:949-53. 2006
    ..We aimed to investigate the prevalence and incidence of atrial fibrillation (AF) in a large European population-based study...
  86. ncbi request reprint Comparing treatment effects after adjustment with multivariable Cox proportional hazards regression and propensity score methods
    Edwin P Martens
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 17:1-8. 2008
    ..To compare adjusted effects of drug treatment for hypertension on the risk of stroke from propensity score (PS) methods with a multivariable Cox proportional hazards (Cox PH) regression in an observational study with censored data...
  87. ncbi request reprint Withdrawal of fall-risk-increasing drugs in older persons: effect on mobility test outcomes
    Nathalie van der Velde
    Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
    Drugs Aging 24:691-9. 2007
    ..Improvement of mobility may be an important factor in this finding and we therefore tested whether mobility tests improved after FRID withdrawal...
  88. ncbi request reprint Adherence to and dosing of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitors in the general population differs according to apolipoprotein E-genotypes
    Anke Hilse Maitland-van der Zee
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Utrecht University, Utrecht, The Netherlands
    Pharmacogenetics 13:219-23. 2003
    ..18 (CI 1.01-10.03) in men. The apoE genotype is associated with discontinuation of statins. This suggests that subjects who are genetically prone to develop hypercholesterolemia show the highest risk of discontinuation of treatment...
  89. ncbi request reprint CYP2C9 genotyping in acenocoumarol treatment: is it a cost-effective addition to international normalized ratio monitoring?
    Tom Schalekamp
    Department of Pharmacoepidemiology and Pharmacotherapy, University Institute of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    Clin Pharmacol Ther 79:511-20. 2006
  90. pmc Determinants of potential drug-drug interaction associated dispensing in community pharmacies in the Netherlands
    Matthijs L Becker
    National Institute of Public Health and the Environment, Bilthoven, The Netherlands
    Pharm World Sci 29:51-7. 2007
    ..The objective of this study was to identify determinants of dispensing undesirable interacting drug combinations by community pharmacies in the Netherlands...
  91. pmc Risk of falls after withdrawal of fall-risk-increasing drugs: a prospective cohort study
    Nathalie van der Velde
    Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
    Br J Clin Pharmacol 63:232-7. 2007
    ..The objective of this study was to identify differences in the incidence of falls after withdrawal (discontinuation or dose reduction) of fall-risk-increasing drugs as a single intervention in older fallers...
  92. pmc Prescribing behaviour according to Dutch and European guidelines on the management of hypercholesterolaemia (1992-1999)
    Aukje K Mantel-Teeuwisse
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences UIPS, Utrecht University, Utrecht, The Netherlands
    Br J Clin Pharmacol 61:592-600. 2006
    ..The success of the full implementation of a new guideline may depend on the observed discrepancy between daily medical practice developed before the release of the guideline and new treatment recommendations issued by the guideline...
  93. doi request reprint Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant
    Bas J M Peters
    Division of Pharmacoepidemiology and Pharmacotherapy, Faculty of Science, Utrecht University, Utrecht, The Netherlands
    Pharmacogenet Genomics 18:631-6. 2008
    ..Therefore, we assessed whether the effectiveness of statins in reducing the risk of MI was modified by the GNB3 C825T polymorphism...
  94. ncbi request reprint Drug costs associated with non-adherence to cholesterol management guidelines for primary prevention of cardiovascular disease in an elderly population: the Rotterdam study
    Pearl D Gumbs
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceuticals Sciences UIPS, Utrecht University, Utrecht, The Netherlands
    Drugs Aging 23:733-41. 2006
    ..However, several studies have established both undertreatment and non-guidelines-indicated treatment with statins, suggesting a suboptimal use of resources...
  95. ncbi request reprint Non-cardiac QTc-prolonging drugs and the risk of sudden cardiac death
    Sabine M J M Straus
    Pharmaco epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Eur Heart J 26:2007-12. 2005
    ..To assess the association between the use of non-cardiac QTc-prolonging drugs and the risk of sudden cardiac death...
  96. pmc Overanticoagulation associated with combined use of lactulose and acenocoumarol or phenprocoumon
    Loes E Visser
    Pharmaco epidemiology Unit, Departments of Internal Medicine and Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Br J Clin Pharmacol 57:522-4. 2004
    ..4, 95% confidence interval 2.2, 5.3). In view of the widespread use of lactulose, especially among the elderly, awareness of this potential drug interaction is required...
  97. ncbi request reprint Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam Study
    Gysèle S Bleumink
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, PO Box 1738, 3000, Rotterdam, The Netherlands
    Eur Heart J 25:1614-9. 2004
    ..To determine the prevalence, incidence rate, lifetime risk and prognosis of heart failure...
  98. ncbi request reprint HMG-CoA reductase inhibitors and the risk of vertebral fracture
    Mariette W C J Schoofs
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam 3000 DR, The Netherlands
    J Bone Miner Res 19:1525-30. 2004
    ..Randomized trials on statins and fractures, carried out in populations at risk for fractures, are needed...
  99. ncbi request reprint Annual revaccination against influenza and mortality risk in community-dwelling elderly persons
    A C G Voordouw
    Pharmaco epidemiology Unit, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
    JAMA 292:2089-95. 2004
    ..Although large-scale observational studies have demonstrated the effectiveness of influenza vaccination, no large studies have systematically addressed the clinical benefit of annual revaccinations...
  100. ncbi request reprint Comparison of two methodologies to analyze exposure to statins in an observational study on effectiveness
    Anke Hilse Maitland-van der Zee
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute of Pharmaceutical Sciences UIPS, Utrecht University, Sorbonnelaan 16, P O BOX 80082, 3508 TB, The Netherlands
    J Clin Epidemiol 57:237-42. 2004
    ..To obtain valid results, the definition of exposure in an observational study is critical. The objective of our study was to compare different exposure definitions for assessing the effectiveness of statins...
  101. ncbi request reprint Repeated nitrate prescriptions as a potential marker for angina pectoris. A comparison with medical information from the Rotterdam Study
    Anke Hilse Maitland-van der Zee
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute of Pharmaceutical Sciences UIPS, Utrecht University, Utrecht, The Netherlands
    Pharm World Sci 25:70-2. 2003
    ..The objective of this study was to determine whether pharmacy records of nitrate prescriptions could be used as a marker of angina pectoris...