E W Steyerberg

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc Predicting asthma in preschool children with asthma symptoms: study rationale and design
    Esther Hafkamp-de Groen
    The Generation R Study Group, Erasmus MC, Rotterdam, The Netherlands
    BMC Pulm Med 12:65. 2012
  2. pmc Incorporating published univariable associations in diagnostic and prognostic modeling
    Thomas P A Debray
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Med Res Methodol 12:121. 2012
  3. pmc Interpreting the concordance statistic of a logistic regression model: relation to the variance and odds ratio of a continuous explanatory variable
    Peter C Austin
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    BMC Med Res Methodol 12:82. 2012
  4. pmc The quality of the evidence base for clinical pathway effectiveness: room for improvement in the design of evaluation trials
    Thomas Rotter
    Office of the Dean, School for Public Health and Primary Care, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    BMC Med Res Methodol 12:80. 2012
  5. pmc Validation of a model to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD: the rotterdam ischemic heart disease and stroke computer simulation (RISC) model
    Bob J H van Kempen
    Department of Epidemiology, Erasmus MC Rotterdam, Dr Molewaterplein 50, Rotterdam, 3015 GE, The Netherlands
    BMC Med 10:158. 2012
  6. pmc Influences of hospital information systems, indicator data collection and computation on reported Dutch hospital performance indicator scores
    Helen A Anema
    Department of Public Health, Academic Medical Center University of Amsterdam, Room J2 211, P, O, Box 22660, Amsterdam NL 1100 DD, The Netherlands
    BMC Health Serv Res 13:212. 2013
  7. pmc The Prevention and Reactivation Care Program: intervention fidelity matters
    Annemarie J B M De Vos
    Institute of Health Policy and Management, Erasmus University Rotterdam, P O Box 1738, 3000, Dr, Rotterdam, The Netherlands
    BMC Health Serv Res 13:29. 2013
  8. pmc Pregnancy and liver adenoma management: PALM-study
    Susanna M van Aalten
    Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    BMC Gastroenterol 12:82. 2012
  9. ncbi request reprint [Diagnostic work-up of severe diseases: simple prediction rules or just a simple test?]
    Ewout W Steyerberg
    Erasmus MC, afd Maatschappelijke Gezondheidszorg, Rotterdam, The Netherlands
    Ned Tijdschr Geneeskd 156:A4715. 2012
  10. pmc Integrated approach to prevent functional decline in hospitalized elderly: the Prevention and Reactivation Care Program (PReCaP)
    Annemarie J B M De Vos
    Institute of Health Policy and Management, Erasmus University Rotterdam, P, O, Box 1738, 3000 DR Rotterdam, The Netherlands
    BMC Geriatr 12:7. 2012

Detail Information

Publications216 found, 100 shown here

  1. pmc Predicting asthma in preschool children with asthma symptoms: study rationale and design
    Esther Hafkamp-de Groen
    The Generation R Study Group, Erasmus MC, Rotterdam, The Netherlands
    BMC Pulm Med 12:65. 2012
    ....
  2. pmc Incorporating published univariable associations in diagnostic and prognostic modeling
    Thomas P A Debray
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Med Res Methodol 12:121. 2012
    ..Currently, methods to incorporate such information in the construction of a prediction model are underdeveloped and unfamiliar to many researchers...
  3. pmc Interpreting the concordance statistic of a logistic regression model: relation to the variance and odds ratio of a continuous explanatory variable
    Peter C Austin
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    BMC Med Res Methodol 12:82. 2012
    ..When outcomes are binary, the c-statistic (equivalent to the area under the Receiver Operating Characteristic curve) is a standard measure of the predictive accuracy of a logistic regression model...
  4. pmc The quality of the evidence base for clinical pathway effectiveness: room for improvement in the design of evaluation trials
    Thomas Rotter
    Office of the Dean, School for Public Health and Primary Care, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    BMC Med Res Methodol 12:80. 2012
    ..The analysis is based on a recently published Cochrane review of the effectiveness of CPWs...
  5. pmc Validation of a model to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD: the rotterdam ischemic heart disease and stroke computer simulation (RISC) model
    Bob J H van Kempen
    Department of Epidemiology, Erasmus MC Rotterdam, Dr Molewaterplein 50, Rotterdam, 3015 GE, The Netherlands
    BMC Med 10:158. 2012
    ..We developed a Monte Carlo Markov model designed to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD. Internal, predictive, and external validity of the model have not yet been established...
  6. pmc Influences of hospital information systems, indicator data collection and computation on reported Dutch hospital performance indicator scores
    Helen A Anema
    Department of Public Health, Academic Medical Center University of Amsterdam, Room J2 211, P, O, Box 22660, Amsterdam NL 1100 DD, The Netherlands
    BMC Health Serv Res 13:212. 2013
    ..This might affect the reliability and plausibility of the nationally reported scores...
  7. pmc The Prevention and Reactivation Care Program: intervention fidelity matters
    Annemarie J B M De Vos
    Institute of Health Policy and Management, Erasmus University Rotterdam, P O Box 1738, 3000, Dr, Rotterdam, The Netherlands
    BMC Health Serv Res 13:29. 2013
    ....
  8. pmc Pregnancy and liver adenoma management: PALM-study
    Susanna M van Aalten
    Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    BMC Gastroenterol 12:82. 2012
    ..We aim to investigate the management and outcome of HCA during pregnancy and labor based on a prospectively acquired online database in the Netherlands...
  9. ncbi request reprint [Diagnostic work-up of severe diseases: simple prediction rules or just a simple test?]
    Ewout W Steyerberg
    Erasmus MC, afd Maatschappelijke Gezondheidszorg, Rotterdam, The Netherlands
    Ned Tijdschr Geneeskd 156:A4715. 2012
    ..Performing a D-dimer test is hence essential in all patients in the selection for a CT scan. Improvements in the prediction rules are necessary to make these meaningful in the diagnostic work-up for pulmonary embolism...
  10. pmc Integrated approach to prevent functional decline in hospitalized elderly: the Prevention and Reactivation Care Program (PReCaP)
    Annemarie J B M De Vos
    Institute of Health Policy and Management, Erasmus University Rotterdam, P, O, Box 1738, 3000 DR Rotterdam, The Netherlands
    BMC Geriatr 12:7. 2012
    ..Thirty-five procent of 70-year old patients experience functional decline during hospital admission in comparison with pre-illness baseline. This percentage increases considerably with age...
  11. pmc Assessing the incremental value of diagnostic and prognostic markers: a review and illustration
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
    Eur J Clin Invest 42:216-28. 2012
    ..New markers may improve prediction of diagnostic and prognostic outcomes. We review various measures to quantify the incremental value of markers over standard, readily available characteristics...
  12. pmc Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management
    Dewkoemar Ramsoekh
    Department of Gastroenterology and Hepatology Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Hered Cancer Clin Pract 7:17. 2009
    ..The risk is dependent of the affected mismatch repair gene. The aim of the present study was to calculate the cumulative risk of LS related cancers in proven MLH1, MSH2 and MSH6 mutation carriers...
  13. pmc The added value of ordinal analysis in clinical trials: an example in traumatic brain injury
    Bob Roozenbeek
    Department of Neurosurgery, Antwerp University Hospital, Wilrijkstraat 10, Edegem, Belgium
    Crit Care 15:R127. 2011
    ..The objective of this study is to quantify the benefits of ordinal analysis in the real-life situation of a large TBI trial...
  14. pmc Optimizing intensive care capacity using individual length-of-stay prediction models
    Mark van Houdenhoven
    Department of Operating Rooms, Erasmus University Medical Center, P, O, Box 2040, 3000 CA Rotterdam, The Netherlands
    Crit Care 11:R42. 2007
    ..To improve planning, we constructed, validated and tested three models designed to predict length of stay (LOS) in the ICU in individual patients...
  15. pmc A multicenter randomized controlled trial evaluating the effect of small stitches on the incidence of incisional hernia in midline incisions
    Joris J Harlaar
    Department of Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    BMC Surg 11:20. 2011
    ....
  16. pmc Neoadjuvant chemoradiation followed by surgery versus surgery alone for patients with adenocarcinoma or squamous cell carcinoma of the esophagus (CROSS)
    M van Heijl
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    BMC Surg 8:21. 2008
    ..The concept that this neoadjuvant chemoradiotherapy regimen improves overall survival has, however, to be proven in a randomized phase III trial...
  17. pmc The ACCOMPLISH study. A cluster randomised trial on the cost-effectiveness of a multicomponent intervention to improve hand hygiene compliance and reduce healthcare associated infections
    Vicki Erasmus
    Erasmus Medical Centre, Department of Public Health, Rotterdam, The Netherlands
    BMC Public Health 11:721. 2011
    ..This study aims to evaluate the cost-effectiveness of a multicomponent implementation strategy aimed at the reduction of healthcare associated infections in Dutch hospital care, by promotion of hand hygiene...
  18. pmc Logistic random effects regression models: a comparison of statistical packages for binary and ordinal outcomes
    Baoyue Li
    Department of Biostatistics, Erasmus MC, Dr, Molewaterplein 50, Rotterdam, The Netherlands
    BMC Med Res Methodol 11:77. 2011
    ..Logistic random effects models are a popular tool to analyze multilevel also called hierarchical data with a binary or ordinal outcome. Here, we aim to compare different statistical software implementations of these models...
  19. pmc Incorporating natural variation into IVF clinic league tables: The Expected Rank
    Hester F Lingsma
    Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
    BMC Med Res Methodol 9:53. 2009
    ..The aim of this study is to compare standard methods for ranking with a novel method that takes into account natural variation...
  20. pmc Prediction of two month modified Rankin Scale with an ordinal prediction model in patients with aneurysmal subarachnoid haemorrhage
    Roelof Risselada
    Department of Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    BMC Med Res Methodol 10:86. 2010
    ..Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating event with a frequently disabling outcome. Our aim was to develop a prognostic model to predict an ordinal clinical outcome at two months in patients with aSAH...
  21. pmc A labelled discrete choice experiment adds realism to the choices presented: preferences for surveillance tests for Barrett esophagus
    Michelle E Kruijshaar
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    BMC Med Res Methodol 9:31. 2009
    ..We conducted a labelled discrete choice experiment with realistic choices to investigate patients' trade-offs between the expected health gains and the burden of testing in surveillance of Barrett esophagus (BE)...
  22. pmc A decision-analytic approach to define poor prognosis patients: a case study for non-seminomatous germ cell cancer patients
    Merel R van Dijk
    Department of Public Health, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    BMC Med Inform Decis Mak 8:1. 2008
    ....
  23. pmc Sensitivity and specificity of single IgA and IgG antibody concentrations for early diagnosis of pertussis in adults: an evaluation for outbreak management in public health practice
    Paul L J M Mertens
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, CA Rotterdam, The Netherlands
    BMC Infect Dis 7:53. 2007
    ..An accurate, practical laboratory test is needed to confirm clinical diagnosis of pertussis in adults during the first 3 symptomatic weeks, when treatment is effective and transmission can be interrupted...
  24. pmc A systematic review and meta-analysis of the effects of clinical pathways on length of stay, hospital costs and patient outcomes
    Thomas Rotter
    Department of Public Health, Dresden Medical School, University of Dresden, Dresden, Germany
    BMC Health Serv Res 8:265. 2008
    ..To provide a framework for local healthcare organisations considering the effectiveness of clinical pathways as a patient management strategy...
  25. pmc Age, gender and disability predict future disability in older people: the Rotterdam Study
    Umit Tas
    Department of General Practice, Erasmus MC University Medical Centre Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    BMC Geriatr 11:22. 2011
    ..To develop a prediction model that predicts disability in community-dwelling older people. Insight in the predictors of disability is needed to target preventive strategies for people at increased risk...
  26. pmc Evaluation design of a reactivation care program to prevent functional loss in hospitalised elderly: a cohort study including a randomised controlled trial
    Kirsten J E Asmus-Szepesi
    Erasmus University Medical Centre, Department of Public Health, Rotterdam, The Netherlands
    BMC Geriatr 11:36. 2011
    ....
  27. pmc Stent versus gastrojejunostomy for the palliation of gastric outlet obstruction: a systematic review
    Suzanne M Jeurnink
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, The Netherlands
    BMC Gastroenterol 7:18. 2007
    ..Recently, stent placement has been introduced as an alternative treatment. We reviewed the available literature on stent placement and GJJ for gastric outlet obstruction, with regard to medical effects and costs...
  28. ncbi request reprint Data reduction for prediction: a case study on robust coding of age and family history for the risk of having a genetic mutation
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
    Stat Med 26:5545-56. 2007
    ..Such robust coding may especially be relevant for modeling in relatively small data sets...
  29. ncbi request reprint Referral patterns, treatment choices, and outcomes in locoregional esophageal cancer: a population-based analysis of elderly patients
    Ewout W Steyerberg
    Center for Medical Decision Making, Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
    J Clin Oncol 25:2389-96. 2007
    ..Referring physicians and treating specialists must ensure that elderly patients are not deprived of the opportunity to consider all of their treatment options...
  30. ncbi request reprint Validation and updating of predictive logistic regression models: a study on sample size and shrinkage
    Ewout W Steyerberg
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands
    Stat Med 23:2567-86. 2004
    ..Parsimonious updating methods were found preferable to more extensive model revisions, which should only be attempted with relatively large validation samples in combination with shrinkage...
  31. pmc Assessing the performance of prediction models: a framework for traditional and novel measures
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
    Epidemiology 21:128-38. 2010
    ..Other measures of performance may be warranted in specific applications, such as reclassification metrics to gain insight into the value of adding a novel predictor to an established model...
  32. ncbi request reprint Racial differences in surgical evaluation, treatment, and outcome of locoregional esophageal cancer: a population-based analysis of elderly patients
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    J Clin Oncol 23:510-7. 2005
    ..We investigated racial disparities in access to surgical evaluation, receipt of surgery, and survival among elderly patients with locoregional esophageal cancer...
  33. ncbi request reprint Equally valid models gave divergent predictions for mortality in acute myocardial infarction patients in a comparison of logistic [corrected] regression models
    Ewout W Steyerberg
    Department of Public Health, Center for Clinical Decision Sciences, Ee2093, Erasmus MC, University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    J Clin Epidemiol 58:383-90. 2005
    ..Models that predict mortality after acute myocardial infarction (AMI) contain different predictors and are based on different populations. We studied the agreement and validity of predictions for individual patients...
  34. doi request reprint [Performance measures for prediction models and markers: evaluation of predictions and classifications]
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, Rotterdam, Paises Bajos
    Rev Esp Cardiol 64:788-94. 2011
    ....
  35. ncbi request reprint Applicability of clinical prediction models in acute myocardial infarction: a comparison of traditional and empirical Bayes adjustment methods
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Am Heart J 150:920. 2005
    ..Updating to local circumstances may be required to make such models better applicable. We aimed to compare traditional and empirical Bayes (EB) methods to perform such updating...
  36. pmc Predicting outcome after traumatic brain injury: development and international validation of prognostic scores based on admission characteristics
    Ewout W Steyerberg
    Center for Medical Decision Sciences, Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
    PLoS Med 5:e165; discussion e165. 2008
    ..A reliable prediction of outcome on admission is of great clinical relevance. We aimed to develop prognostic models with readily available traditional and novel predictors...
  37. ncbi request reprint Internal and external validation of predictive models: a simulation study of bias and precision in small samples
    Ewout W Steyerberg
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus MC, PO Box 1738 3000 DR, Rotterdam, The Netherlands
    J Clin Epidemiol 56:441-7. 2003
    ..For external validation, substantial sample sizes should be used for sufficient power to detect clinically important changes in performance as compared with the internally validated estimate...
  38. ncbi request reprint Prediction of indolent prostate cancer: validation and updating of a prognostic nomogram
    E W Steyerberg
    Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Urol 177:107-12; discussion 112. 2007
    ..Statistical models have been proposed to predict indolent cancer. We validated and updated model predictions for a screening setting...
  39. ncbi request reprint Surgical mortality in patients with esophageal cancer: development and validation of a simple risk score
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Clin Oncol 24:4277-84. 2006
    ..We aimed to develop and validate a simple risk score for surgical mortality that could be applied to administrative data...
  40. pmc Prediction of intracranial findings on CT-scans by alternative modelling techniques
    Tjeerd van der Ploeg
    Medical Centre Alkmaar Inholland University, Alkmaar, The Netherlands
    BMC Med Res Methodol 11:143. 2011
    ..This study investigates whether alternative modelling techniques might improve the applicability and simplicity of such prediction rules...
  41. ncbi request reprint Retroperitoneal metastases in testicular cancer: role of CT measurements of residual masses in decision making for resection after chemotherapy
    E W Steyerberg
    Dept of Public Health, Center for Clinical Decision Sciences, Ee 2091, Erasmus University, 3000 DR Rotterdam, The Netherlands
    Radiology 215:437-44. 2000
    ..To determine the relative importance of computed tomographic (CT) measurements for the prediction of histologic findings in residual masses in patients with nonseminomatous testicular cancer...
  42. pmc Nurse-led follow-up of patients after oesophageal or gastric cardia cancer surgery: a randomised trial
    E M L Verschuur
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Br J Cancer 100:70-6. 2009
    ..This type of care is very likely to be more cost effective than physician-led follow-up...
  43. doi request reprint Cost comparison of gastrojejunostomy versus duodenal stent placement for malignant gastric outlet obstruction
    S M Jeurnink
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, Rotterdam, The Netherlands
    J Gastroenterol 45:537-43. 2010
    ..As health economic aspects have only been studied in general terms, we estimated the cost of GJJ and that of stent placement in such patients...
  44. doi request reprint A prognostic model for amputation in critical lower limb ischemia
    H M Klomp
    Department of Public Health, Center for Clinical Decision Sciences, Erasmus MC
    Vasc Med 14:109-15. 2009
    ..In conclusion, in patients with critical lower limb ischemia, the presence of ischemic skin lesions and the described radiological arterial disease score can be used to estimate amputation risk...
  45. doi request reprint What determines individuals' preferences for colorectal cancer screening programmes? A discrete choice experiment
    L van Dam
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, Room Ba 393, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Eur J Cancer 46:150-9. 2010
    ..In many countries uptake of colorectal cancer (CRC) screening remains low...
  46. doi request reprint Surgical gastrojejunostomy or endoscopic stent placement for the palliation of malignant gastric outlet obstruction (SUSTENT study): a multicenter randomized trial
    Suzanne M Jeurnink
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Gastrointest Endosc 71:490-9. 2010
    ..Both gastrojejunostomy (GJJ) and stent placement are commonly used palliative treatments of obstructive symptoms caused by malignant gastric outlet obstruction (GOO)...
  47. ncbi request reprint Self-expanding metal stents for complicated and recurrent esophagogastric cancer
    P D Siersema
    Department of Gastroenterology and Hepatology, University Hospital Rotterdam-Dijkzigt, Rotterdam, The Netherlands
    Gastrointest Endosc 54:579-86. 2001
    ..Placement should be considered at an early stage in these conditions...
  48. ncbi request reprint Decision analyses for prophylactic replacement of the Björk-Shiley convexo-concave heart valve: an evaluation of assumptions and estimates
    E W Steyerberg
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus University, Rotterdam, The Netherlands
    Med Decis Making 20:20-32. 2000
    ..The variation in essential assumptions of previous decision analyses directly affected the indication for prophylactic replacement. This study shows how detailed statistical analyses may guide modeling choices in a decision analysis...
  49. ncbi request reprint Anticipated costs of hospitalization for respiratory syncytial virus infection in young children at risk
    Edwin Rietveld
    Department of Pediatrics, Erasmus MC Sophia, Rotterdam, The Netherlands
    Pediatr Infect Dis J 23:523-9. 2004
    ..We aimed to develop a model that predicts anticipated mean RSV hospitalization costs of groups of young children at risk for hospitalization, but not yet hospitalized, based on readily available child characteristics...
  50. ncbi request reprint Stent placement or brachytherapy for palliation of dysphagia from esophageal cancer: a prognostic model to guide treatment selection
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, The Netherlands
    Gastrointest Endosc 62:333-40. 2005
    ..The benefit of brachytherapy, however, only occurred after a relatively long survival. The objective is to develop a model that distinguishes patients with a poor prognosis from those with a relatively good prognosis...
  51. doi request reprint Undertriage in the Manchester triage system: an assessment of severity and options for improvement
    N Seiger
    Department of Paediatrics, Erasmus MC Sophia Children s Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Arch Dis Child 96:653-7. 2011
    ..The aim of the study was to assess the clinical severity of undertriaged patients in the MTS and to define the determinants of undertriage...
  52. pmc The role of socio-economic status in the decision making on diagnosis and treatment of oesophageal cancer in The Netherlands
    E P M van Vliet
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Br J Cancer 95:1180-5. 2006
    ..Moreover, the correlations between SES and different treatment modalities suggest that both patient and doctor determinants contribute to the decision on the most optimal treatment modality in patients with oesophageal cancer...
  53. ncbi request reprint Prognostic modelling with logistic regression analysis: a comparison of selection and estimation methods in small data sets
    E W Steyerberg
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus University, Rotterdam, The Netherlands
    Stat Med 19:1059-79. 2000
    ..We therefore recommend shrinkage methods in full models including prespecified predictors and incorporation of external information, when prognostic models are constructed in small data sets...
  54. pmc Predictors of complications after endoscopic retrograde cholangiopancreatography: a prognostic model for early discharge
    S M Jeurnink
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Surg Endosc 25:2892-900. 2011
    ....
  55. ncbi request reprint Prognostic models based on literature and individual patient data in logistic regression analysis
    E W Steyerberg
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus University, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Stat Med 19:141-60. 2000
    ..We conclude that prognostic models may benefit substantially from explicit incorporation of literature data...
  56. ncbi request reprint Residual mass histology in testicular cancer: development and validation of a clinical prediction rule
    E W Steyerberg
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus Medical Center Rotterdam, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Stat Med 20:3847-59. 2001
    ..83 and 0.82). This study illustrates that a careful modelling strategy may result in an adequate predictive model. Further study of model validity may stimulate application in clinical practice...
  57. ncbi request reprint Prognosis after aortic valve replacement with a bioprosthesis: predictions based on meta-analysis and microsimulation
    J P Puvimanasinghe
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands
    Circulation 103:1535-41. 2001
    ..This information will be useful for patient counseling and clinical decision making. It also could serve as a baseline for the evaluation of newer valve types...
  58. doi request reprint Value of genetic profiling for the prediction of coronary heart disease
    Jeroen B van der Net
    Department of Public Health, Erasmus MC University Medical Center Rotterdam, Dr Molewaterplein 50 60, Rotterdam, The Netherlands
    Am Heart J 158:105-10. 2009
    ..This may improve CHD risk prediction. The aim of the present simulation study was to investigate to what degree CHD risk can be predicted by testing multiple genetic variants (genetic profiling)...
  59. ncbi request reprint Prognostic modeling with logistic regression analysis: in search of a sensible strategy in small data sets
    E W Steyerberg
    Department of Public Health, Erasmus University, Rotterdam, The Netherlands
    Med Decis Making 21:45-56. 2001
    ..In conclusion, a sensible strategy in small data sets is to apply shrinkage methods in full models that include well-coded predictors that are selected based on external information...
  60. pmc Detection of distant metastases in patients with oesophageal or gastric cardia cancer: a diagnostic decision analysis
    E P M van Vliet
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Br J Cancer 97:868-76. 2007
    ..It remains to be determined whether the application of positron emission tomography will further increase sensitivities and specificities of metastases detection without jeopardising costs and QALYs...
  61. doi request reprint Cost-effectiveness and quality-of-life analysis of physician-staffed helicopter emergency medical services
    A N Ringburg
    Department of Surgery Traumatology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
    Br J Surg 96:1365-70. 2009
    ..The aim of this study was to investigate the cost-effectiveness of HEMS assistance compared with emergency medical services (EMS)...
  62. ncbi request reprint Predicting presence of intestinal metaplasia and dysplasia in columnar-lined esophagus: a multivariate analysis
    M Kerkhof
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Endoscopy 39:772-8. 2007
    ..In patients with presumed Barrett esophagus we evaluated clinical risk factors that could predict the presence of intestinal metaplasia and dysplasia in biopsies of columnar-lined esophagus (CLE), independently of histological results...
  63. ncbi request reprint Incisional hernia after repair of wound dehiscence: incidence and risk factors
    Riet Martijne T van't
    Department of Surgery, Erasmus University Medical Center, Rotterdam Dijkzigt, Rotterdam, The Netherlands
    Am Surg 70:281-6. 2004
    ..Incisional hernia develops in the majority of patients after wound dehiscence repair, regardless of suture material or technique. Aneurysm of the abdominal aorta and severe dehiscence with evisceration predispose to incisional hernia...
  64. doi request reprint Impact of age and co-morbidity on surgical resection rate and survival in patients with oesophageal and gastric cancer
    L B Koppert
    Department of Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands
    Br J Surg 99:1693-700. 2012
    ..The aim of this study was to investigate the association between patient characteristics, resection rates and survival among patients with oesophageal or gastric cancer...
  65. pmc Preferences for colorectal cancer screening strategies: a discrete choice experiment
    L Hol
    Departments of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre, s Gravendijkwal 230, Rotterdam, The Netherlands
    Br J Cancer 102:972-80. 2010
    ..We conducted a study to determine the preferences of individuals and to predict uptake for colorectal cancer (CRC) screening programmes using various screening tests...
  66. pmc Antibiotic prophylaxis for haematogenous bacterial arthritis in patients with joint disease: a cost effectiveness analysis
    P Krijnen
    Center for Clinical Decision Sciences, Department of Public Health, Erasmus University, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Ann Rheum Dis 60:359-66. 2001
    ..To assess the cost effectiveness of antibiotic prophylaxis for haematogenous bacterial arthritis in patients with joint disease...
  67. ncbi request reprint Environmental risk factors in the development of adenocarcinoma of the oesophagus or gastric cardia: a cross-sectional study in a Dutch cohort
    P J F DE Jonge
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Aliment Pharmacol Ther 26:31-9. 2007
    ..Risk factors for adenocarcinoma of the oesophagus (OAC) and gastric cardia (GCA) are not yet established...
  68. ncbi request reprint Gastrojejunostomy versus stent placement in patients with malignant gastric outlet obstruction: a comparison in 95 patients
    S M Jeurnink
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, The Netherlands
    J Surg Oncol 96:389-96. 2007
    ..In this retrospective study, we compared GJJ and stent placement with regard to medical effects...
  69. ncbi request reprint A clinical prediction rule for renal artery stenosis
    P Krijnen
    Center for Clinical Decision Sciences and University Hospital Dijkzigt, Erasmus University, Rotterdam, The Netherlands
    Ann Intern Med 129:705-11. 1998
    ..Renal artery stenosis is a rare cause of hypertension. The gold standard for diagnosing renal artery stenosis, renal angiography, is invasive and costly...
  70. ncbi request reprint Publication bias does not play a role in the reporting of the results of endoscopic ultrasound staging of upper gastrointestinal cancers
    E P M van Vliet
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Endoscopy 39:325-32. 2007
    ..In this study, we assessed whether publication bias was also present in the reporting of EUS staging results in upper gastrointestinal cancer...
  71. ncbi request reprint Grading of dysplasia in Barrett's oesophagus: substantial interobserver variation between general and gastrointestinal pathologists
    M Kerkhof
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Histopathology 50:920-7. 2007
    ..To determine interobserver variation in grading of dysplasia in Barrett's oesophagus (BO) between non-expert general pathologists and expert gastrointestinal pathologists on the one hand and between expert pathologists on the other hand...
  72. ncbi request reprint Patients' perceived burden of cystoscopic and urinary surveillance of bladder cancer: a randomized comparison
    Madelon N M van der Aa
    Department of Pathology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    BJU Int 101:1106-10. 2008
    ....
  73. ncbi request reprint Admission of patients with severe and moderate traumatic brain injury to specialized ICU facilities: a search for triage criteria
    Chantal W P M Hukkelhoven
    Department of Public Health, Center for Clinical Decision Science, Erasmus MC, Rotterdam, The Netherlands
    Intensive Care Med 31:799-806. 2005
    ..To investigate whether triage for direct admission of patients with traumatic brain injury to a trauma center is facilitated by predicting the risk of potentially removable lesions or raised intracranial pressure (ICP)...
  74. ncbi request reprint Prediction models for the histology of residual masses after chemotherapy for metastatic testicular cancer. ReHiT Study Group
    E W Steyerberg
    Department of Public Health, Erasmus Medical Center Rotterdam, The Netherlands
    Int J Cancer 83:856-9. 1999
    ..The probability-based policies could refine the selection without such an increase in the number of resections. Prediction models for the residual histology therefore merit wider application in clinical practice...
  75. doi request reprint Predictors for neoplastic progression in patients with Barrett's Esophagus: a prospective cohort study
    M Sikkema
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Am J Gastroenterol 106:1231-8. 2011
    ..The aim of this study was to identify such predictors of progression to high-grade dysplasia (HGD) and EAC in patients with BE after 4 years of surveillance and to develop a prediction model based on these factors...
  76. ncbi request reprint Does CDX2 expression predict Barrett's metaplasia in oesophageal columnar epithelium without goblet cells?
    M Kerkhof
    Department of Gastroenterology and Hepatology, Erasus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Aliment Pharmacol Ther 24:1613-21. 2006
    ..As intestinal metaplasia and cardiac-type mucosa are endoscopically indiscernible, it is difficult to take targeted samples from columnar-lined oesophagus with consequently a risk of having undetected intestinal metaplasia...
  77. doi request reprint Statin treatment after a recent TIA or stroke: is effectiveness shown in randomized clinical trials also observed in everyday clinical practice?
    H F Lingsma
    Department of Public Health, Erasmus Medical Centre, Rotterdam, The Netherlands
    Acta Neurol Scand 122:15-20. 2010
    ....
  78. pmc Resection of residual retroperitoneal masses in testicular cancer: evaluation and improvement of selection criteria. The ReHiT study group. Re-analysis of histology in testicular cancer
    E W Steyerberg
    Department of Public Health, Erasmus University, Rotterdam, The Netherlands
    Br J Cancer 74:1492-8. 1996
    ..We conclude that a simple statistical model, based on a limited number of patient characteristics, provides better guidelines for patient selection than those currently used in clinical practice...
  79. doi request reprint What is the evidence on efficacy of spinal cord stimulation in (subgroups of) patients with critical limb ischemia?
    H M Klomp
    Department of General Surgery, Vascular Unit, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Ann Vasc Surg 23:355-63. 2009
    ..Although some factors provide prognostic information as to the risk of amputation in patients with CLI, there are no data supporting a more favorable treatment effect in any group...
  80. doi request reprint Radiologist experience and CT examination quality determine metastasis detection in patients with esophageal or gastric cardia cancer
    E P M van Vliet
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Eur Radiol 18:2475-84. 2008
    ..Therefore, we suggest that staging procedures for esophageal and gastric cardia cancer should preferably be performed in centers with technically advanced equipment and experienced radiologists...
  81. doi request reprint Prediction of 30-day mortality after endovascular repair or open surgery in patients with ruptured abdominal aortic aneurysms
    Jacob J Visser
    Department Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    J Vasc Surg 49:1093-9. 2009
    ....
  82. ncbi request reprint Baseline characteristics and statistical power in randomized controlled trials: selection, prognostic targeting, or covariate adjustment?
    Bob Roozenbeek
    Department of Public Health, Center for Medical Decision Making, Erasmus MC, Rotterdam, The Netherlands
    Crit Care Med 37:2683-90. 2009
    ..We aimed to investigate the potential benefits of different approaches for dealing with heterogeneity in a case study on traumatic brain injury (TBI)...
  83. doi request reprint Amino-terminal pro-B-type natriuretic peptide improves cardiovascular and cerebrovascular risk prediction in the population: the Rotterdam study
    Joost H W Rutten
    Department of Internal Medicine, Room D432, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands
    Hypertension 55:785-91. 2010
    ....
  84. ncbi request reprint Prognosis after aortic root replacement with cryopreserved allografts in adults
    Johanna J M Takkenberg
    Department of Cardio Thoracic Surgery, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
    Ann Thorac Surg 75:1482-9. 2003
    ..Meta-analysis and microsimulation were used to calculate age-specific long-term prognosis after allograft aortic root replacement based on current evidence...
  85. pmc Men's preferences for prostate cancer screening: a discrete choice experiment
    E W de Bekker-Grob
    Department of Public Health, Erasmus MC University Medical Centre Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Br J Cancer 108:533-41. 2013
    ..Screening for prostate cancer (PC) may save lives, but overdiagnosis and overtreatment are serious drawbacks. We aimed to determine men's preferences for PC screening, and to elicit the trade-offs they make...
  86. pmc Early recognition of poor prognosis in Guillain-Barre syndrome
    C Walgaard
    Department of Neurology, Erasmus MC, University Medical Centre, 3000 CA Rotterdam, The Netherlands
    Neurology 76:968-75. 2011
    ..We developed a clinical prognostic model for early prediction of outcome in GBS, applicable for clinical practice and future therapeutic trials...
  87. ncbi request reprint Identifying subgroups among poor prognosis patients with nonseminomatous germ cell cancer by tree modelling: a validation study
    M R van Dijk
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Ann Oncol 15:1400-5. 2004
    ..These patients might profit most from more intensive treatment strategies. For this purpose, a regression tree was previously developed on 332 patients. We aimed to evaluate the performance and structure of this tree...
  88. ncbi request reprint Experiences and expectations of patients after oesophageal cancer surgery: an explorative study
    E M L Verschuur
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Eur J Cancer Care (Engl) 15:324-32. 2006
    ..Psychosocial problems are also present, but care is less commonly expected. Nurses' involvement during follow-up could be a way to optimize patients' management after oesophageal cancer surgery...
  89. ncbi request reprint The burden of upper gastrointestinal endoscopy in patients with Barrett's esophagus
    M E Kruijshaar
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Endoscopy 38:873-8. 2006
    ..We assessed to what extent patients perceived this procedure as burdensome...
  90. pmc Comparing and ranking hospitals based on outcome: results from The Netherlands Stroke Survey
    H F Lingsma
    Department of Public Health, Erasmus MC, CA Rotterdam, The Netherlands
    QJM 103:99-108. 2010
    ..Measuring quality of care and ranking hospitals with outcome measures poses two major methodological challenges: case-mix adjustment and variation that exists by chance...
  91. ncbi request reprint Internal validation of predictive models: efficiency of some procedures for logistic regression analysis
    E W Steyerberg
    Center for Clinical Decision Sciences, Ee 2091, Department of Public Health, Erasmus University, P O Box 1738, 3000 DR, Rotterdam, The Netherlands
    J Clin Epidemiol 54:774-81. 2001
    ..We conclude that split-sample validation is inefficient, and recommend bootstrapping for estimation of internal validity of a predictive logistic regression model...
  92. ncbi request reprint A comparison between low-volume referring regional centers and a high-volume referral center in quality of preoperative metastasis detection in esophageal carcinoma
    Evelyn P M van Vliet
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Am J Gastroenterol 101:234-42. 2006
    ..In this study, we compared the quality of preoperative metastasis detection between a high-volume referral center with that of low-volume referring regional centers...
  93. ncbi request reprint Prognostic value of demographic characteristics in traumatic brain injury: results from the IMPACT study
    Nino A Mushkudiani
    Center for Medical Decision Making, Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands
    J Neurotrauma 24:259-69. 2007
    ..We conclude that outcome following TBI is dependent on age, race, to a lesser extent on education, but not on gender...
  94. ncbi request reprint Risk factors for the development of esophageal adenocarcinoma in Barrett's esophagus
    Pieter J F de Jonge
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Am J Gastroenterol 101:1421-9. 2006
    ..To identify risk factors for esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus (BE)...
  95. doi request reprint Factors that predict response of patients with hepatitis B e antigen-positive chronic hepatitis B to peginterferon-alfa
    Erik H C J Buster
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Gastroenterology 137:2002-9. 2009
    ..We analyzed data from the 2 largest global trials of hepatitis B e antigen (HBeAg)-positive patients with chronic hepatitis B to determine which are most likely to respond to PEG-IFN-alfa therapy...
  96. ncbi request reprint Patients with Barrett's esophagus perceive their risk of developing esophageal adenocarcinoma as low
    Michelle E Kruijshaar
    Department of Public Health, Erasmus MC University Medical Center Rotterdam, The Netherlands
    Gastrointest Endosc 65:26-30. 2007
    ..The risk of developing esophageal adenocarcinoma (EAC) for patients with Barrett's esophagus (BE) is approximately 0.5% per year...
  97. doi request reprint ABCG8 gene polymorphisms, plasma cholesterol concentrations, and risk of cardiovascular disease in familial hypercholesterolemia
    Kristel C M C Koeijvoets
    Department of Internal Medicine, Rotterdam, The Netherlands
    Atherosclerosis 204:453-8. 2009
    ..57, 95% CI 1.13-2.18; p=0.01) and CHD (RR 1.72, 95% CI 1.23-2.41; p=0.002). In conclusion, our data suggest that genetic variation in the ABCG8 gene may influence the burden of atherosclerosis...
  98. pmc Patients' and urologists' preferences for prostate cancer treatment: a discrete choice experiment
    E W de Bekker-Grob
    Department of Public Health, Erasmus MC University Medical Centre Rotterdam, PO Box 2040, Rotterdam, The Netherlands
    Br J Cancer 109:633-40. 2013
    ..This implies that urologists need to be aware of potential differences compared with the patient's perspective on treatment decisions in shared decision making on PC treatment. ..
  99. doi request reprint Repeatability of the Manchester Triage System for children
    M van Veen
    Department of Paediatrics, Erasmus MC Sophia Children s Hospital, University Medical Center Rotterdam, 3000 CB Rotterdam, The Netherlands
    Emerg Med J 27:512-6. 2010
    ..The authors aimed to assess the repeatability of the Manchester Triage System (MTS) in children...
  100. doi request reprint The effects of guideline implementation for proton pump inhibitor prescription on two pulmonary medicine wards
    E P M van Vliet
    Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Aliment Pharmacol Ther 29:213-21. 2009
    ..It has been demonstrated that 40% of patients admitted to pulmonary medicine wards use proton pump inhibitors (PPIs) without a registered indication...
  101. pmc Prediction of 60 day case-fatality after aneurysmal subarachnoid haemorrhage: results from the International Subarachnoid Aneurysm Trial (ISAT)
    R Risselada
    Department of Medical Informatics, Erasmus MC, room Ee 2159, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 25:261-6. 2010
    ....