Research Topics
Species | Sonia M RossoSummaryAffiliation: Erasmus MC Country: The Netherlands Publications
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Detail Information
Publications
Total tau and phosphorylated tau 181 levels in the cerebrospinal fluid of patients with frontotemporal dementia due to P301L and G272V tau mutationsSonia M Rosso
Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
Arch Neurol 60:1209-13. 2003..Mutations in the tau gene have been found in the familial form of FTD, linked to chromosome 17q21-22, showing a spectrum of tauopathy...
Medical and environmental risk factors for sporadic frontotemporal dementia: a retrospective case-control studyS M Rosso
Departments of Neurology, Erasmus Medical Centre Rotterdam, Rotterdam, Netherlands
J Neurol Neurosurg Psychiatry 74:1574-6. 2003..9 to 7.9), which was not statistically significant (p = 0.09) owing to limited power. As altered thyroid hormone status has been observed before in frontotemporal dementia, future studies will be important to confirm this observation...- Variable phenotypic expression and extensive tau pathology in two families with the novel tau mutation L315REsther van Herpen
Department of Clinical Genetics, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
Ann Neurol 54:573-81. 2003..All six tau isoforms were present in soluble brain tau. Recombinant tau proteins with the L315R mutation showed a reduced ability to promote microtubule assembly... - Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based studySonia M Rosso
Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
Brain 126:2016-22. 2003..The finding of tau mutations in 32% of patients with a positive family history for dementia justifies mutation screening in FTD patients with a positive family history, while tau mutations in non-familiar cases are rare... - Phenotypic variation in frontotemporal dementia and parkinsonism linked to chromosome 17John C van Swieten
Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
Dement Geriatr Cogn Disord 17:261-4. 2004..Future research should focus on the role of other genetic and environmental factors in this form of FTDP-17, whereas the responsible gene defect(s) has still to be identified for hereditary FTD without tau mutations... - A novel tau mutation, S320F, causes a tauopathy with inclusions similar to those in Pick's diseaseSonia M Rosso
Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
Ann Neurol 51:373-6. 2002..Recombinant tau protein with the S320F mutation showed a greatly reduced ability to promote microtubule assembly... 
Survival in progressive supranuclear palsy and frontotemporal dementiaWang Zheng Chiu
Department of Neurology, Erasmus University Medical Centre Rotterdam, Room Hs 611, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
J Neurol Neurosurg Psychiatry 81:441-5. 2010..To compare survival and to identify prognostic predictors for progressive supranuclear palsy and frontotemporal dementia...- New developments in frontotemporal dementia and parkinsonism linked to chromosome 17Sonia M Rosso
Department of Neurology, Erasmus Medical Centre, University Hospital-Dijkzigt, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
Curr Opin Neurol 15:423-8. 2002.... - CHMP2B mutations are not a cause of dementia in Dutch patients with familial and sporadic frontotemporal dementiaPatrizia Rizzu
Department of Human Genetics, Section Medical Genomics, VU University, Amsterdam, The Netherlands
Am J Med Genet B Neuropsychiatr Genet 141:944-6. 2006..Our results suggest that mutations in CHMP2B are a rare cause of FTD as compared to MAPT mutations...