Janne M Papma


Affiliation: Erasmus MC
Country: The Netherlands


  1. Panman J, Jiskoot L, Bouts M, Meeter L, van der Ende E, Poos J, et al. Gray and white matter changes in presymptomatic genetic frontotemporal dementia: a longitudinal MRI study. Neurobiol Aging. 2019;76:115-124 pubmed publisher
    ..This study shows distinct presymptomatic cross-sectional and longitudinal patterns of GM and WM changes across C9orf72 repeat expansion, MAPT, and GRN mutation carriers compared with noncarriers. ..
  2. Jiskoot L, Panman J, van Asseldonk L, Franzen S, Meeter L, Donker Kaat L, et al. Longitudinal cognitive biomarkers predicting symptom onset in presymptomatic frontotemporal dementia. J Neurol. 2018;265:1381-1392 pubmed publisher
    ..Using longitudinal neuropsychological assessment, we detected a mutation-specific pattern of cognitive decline, potentially suggesting prognostic value of neuropsychological trajectories in conversion to symptomatic FTD. ..
  3. Jiskoot L, Dopper E, Heijer T, Timman R, van Minkelen R, van Swieten J, et al. Presymptomatic cognitive decline in familial frontotemporal dementia: A longitudinal study. Neurology. 2016;87:384-91 pubmed publisher
    ..g., social cognition, memory, and visuoconstruction. Our results confirm the prognostic value of neuropsychological assessment as a potential clinical biomarker in the presymptomatic phase of familial FTD. ..
  4. Papma J, Smits M, de Groot M, Mattace Raso F, van der Lugt A, Vrooman H, et al. The effect of hippocampal function, volume and connectivity on posterior cingulate cortex functioning during episodic memory fMRI in mild cognitive impairment. Eur Radiol. 2017;27:3716-3724 pubmed publisher
    ..PCC functioning during episodic memory does not relate to hippocampal structure in MCI. • Functional network changes are an important predictor of PCC functioning in MCI. ..
  5. Papma J, Jiskoot L, Panman J, Dopper E, den Heijer T, Donker Kaat L, et al. Cognition and gray and white matter characteristics of presymptomatic C9orf72 repeat expansion. Neurology. 2017;89:1256-1264 pubmed publisher
    ..These findings suggest that neuropsychological assessment, T1-weighted MRI, and diffusion tensor imaging might be useful to identify early biomarkers in the presymptomatic stage of FTD or amyotrophic lateral sclerosis. ..