Jan Nouwen

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc Staphylococcus aureus carriage patterns and the risk of infections associated with continuous peritoneal dialysis
    Jan Nouwen
    Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, The Netherlands
    J Clin Microbiol 44:2233-6. 2006
  2. ncbi request reprint Predicting the Staphylococcus aureus nasal carrier state: derivation and validation of a "culture rule"
    Jan L Nouwen
    Department of Medical Microbiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Clin Infect Dis 39:806-11. 2004
  3. pmc Human factor in Staphylococcus aureus nasal carriage
    Jan Nouwen
    Erasmus MC, Department of Medical Microbiology and Infectious Diseases, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Infect Immun 72:6685-8. 2004
  4. ncbi request reprint Persistent (not intermittent) nasal carriage of Staphylococcus aureus is the determinant of CPD-related infections
    Jan L Nouwen
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Kidney Int 67:1084-92. 2005
  5. ncbi request reprint Staphylococcus aureus nasal carriage is not associated with known polymorphism in the Vitamin D receptor gene
    Mark Claassen
    Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    FEMS Immunol Med Microbiol 43:173-6. 2005
  6. doi request reprint Co-evolutionary aspects of human colonisation and infection by Staphylococcus aureus
    Alex van Belkum
    Department of Medical Microbiology and Infectious Diseases, Unit Research and Development, Erasmus MC, Rotterdam, The Netherlands
    Infect Genet Evol 9:32-47. 2009
  7. ncbi request reprint The role of human innate immune factors in nasal colonization by Staphylococcus aureus
    Alex van Belkum
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Microbes Infect 9:1471-7. 2007
  8. pmc Severity of nonbullous Staphylococcus aureus impetigo in children is associated with strains harboring genetic markers for exfoliative toxin B, Panton-Valentine leukocidin, and the multidrug resistance plasmid pSK41
    Sander Koning
    Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands
    J Clin Microbiol 41:3017-21. 2003
  9. doi request reprint Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils
    Marieke Emonts
    Department of Pediatrics, Sophia Children s Hospital, University Medical Center, Rotterdam, The Netherlands
    J Infect Dis 197:1244-53. 2008
  10. ncbi request reprint Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms
    Erica L T Van Den Akker
    Department of Internal Medicine, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands
    J Infect Dis 194:814-8. 2006

Collaborators

Detail Information

Publications17

  1. pmc Staphylococcus aureus carriage patterns and the risk of infections associated with continuous peritoneal dialysis
    Jan Nouwen
    Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, The Netherlands
    J Clin Microbiol 44:2233-6. 2006
    ..No methicillin or vancomycin resistance was detected...
  2. ncbi request reprint Predicting the Staphylococcus aureus nasal carrier state: derivation and validation of a "culture rule"
    Jan L Nouwen
    Department of Medical Microbiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Clin Infect Dis 39:806-11. 2004
    ..aureus carrier states is obligatory. We set out to develop a "culture rule" capable of differentiating between persistent and intermittent or noncarriers that uses a minimum of nasal swab cultures...
  3. pmc Human factor in Staphylococcus aureus nasal carriage
    Jan Nouwen
    Erasmus MC, Department of Medical Microbiology and Infectious Diseases, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Infect Immun 72:6685-8. 2004
    ..Using a human nasal inoculation model, we here demonstrate that the human factor is an important determinant of S. aureus nasal carriage...
  4. ncbi request reprint Persistent (not intermittent) nasal carriage of Staphylococcus aureus is the determinant of CPD-related infections
    Jan L Nouwen
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Kidney Int 67:1084-92. 2005
    ..We investigated the impact of staphylococcal carriage among patients on continuous peritoneal dialysis (CPD) in a university hospital...
  5. ncbi request reprint Staphylococcus aureus nasal carriage is not associated with known polymorphism in the Vitamin D receptor gene
    Mark Claassen
    Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    FEMS Immunol Med Microbiol 43:173-6. 2005
    ..Our study into genetic determinants of S. aureus carriage patterns is the largest in the field, but still we found no association between VDR gene variation and S. aureus nasal carriage...
  6. doi request reprint Co-evolutionary aspects of human colonisation and infection by Staphylococcus aureus
    Alex van Belkum
    Department of Medical Microbiology and Infectious Diseases, Unit Research and Development, Erasmus MC, Rotterdam, The Netherlands
    Infect Genet Evol 9:32-47. 2009
    ..When the nature of these states would be known in more detail, this knowledge could be used to design novel and empirical, knowledge-driven means of preventing colonisation from proceeding into S. aureus infection...
  7. ncbi request reprint The role of human innate immune factors in nasal colonization by Staphylococcus aureus
    Alex van Belkum
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Microbes Infect 9:1471-7. 2007
    ..aureus carriage predisposition. However, MBL haplotypes do so significantly. Baseline HNP1-3 production is more the consequence of S. aureus colonization than a reason for the (non) carrier status...
  8. pmc Severity of nonbullous Staphylococcus aureus impetigo in children is associated with strains harboring genetic markers for exfoliative toxin B, Panton-Valentine leukocidin, and the multidrug resistance plasmid pSK41
    Sander Koning
    Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands
    J Clin Microbiol 41:3017-21. 2003
    ..The identification of these microbial genetic markers, which are predictive of the severity and the course of the disease, will facilitate guided individualized antimicrobial therapy in the future...
  9. doi request reprint Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils
    Marieke Emonts
    Department of Pediatrics, Sophia Children s Hospital, University Medical Center, Rotterdam, The Netherlands
    J Infect Dis 197:1244-53. 2008
    ..We hypothesized that polymorphisms in host inflammatory response genes and genetic variation in S. aureus contribute to susceptibility to S. aureus carriage and infection...
  10. ncbi request reprint Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms
    Erica L T Van Den Akker
    Department of Internal Medicine, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands
    J Infect Dis 194:814-8. 2006
    ..Thus, genotype-dependent variation in the sensitivity to glucocorticoids is associated with tolerance toward staphylococcal nasal colonization...
  11. ncbi request reprint The role of nasal carriage in Staphylococcus aureus infections
    Heiman F L Wertheim
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, Netherlands
    Lancet Infect Dis 5:751-62. 2005
    ..We present an overview of the current knowledge of the determinants (both human and bacterial) and risks of S aureus nasal carriage. Studies on the population dynamics of S aureus are also summarised...
  12. doi request reprint Host-microbe interplay in persistent Staphylococcus aureus nasal carriage in HIV patients
    Damian C Melles
    Department of Medical Microbiology and Infectious Diseases, room L 313, Erasmus MC, University Medical Center Rotterdam, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Microbes Infect 10:151-8. 2008
    ..2%) and no PVL positive strains were detected. The population structure of S. aureus strains isolated from HIV patients appeared to be strongly overlapping with that of S. aureus isolates from healthy individuals...
  13. ncbi request reprint Strict infection control measures do not prevent clonal spread of coagulase negative staphylococci colonizing central venous catheters in neutropenic hemato-oncologic patients
    Cindy van Pelt
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center Rotterdam, Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    FEMS Immunol Med Microbiol 38:153-8. 2003
    ..In conclusion, despite a constant rate of CRI and implementation of optimal patient care, clonal spread of MRSE strains was not prevented by strict hygiene measures...
  14. pmc Clonal distribution and differential occurrence of the enterotoxin gene cluster, egc, in carriage- versus bacteremia-associated isolates of Staphylococcus aureus
    Alex van Belkum
    Erasmus MC, University Medical Center Rotterdam, room L 313, Department of Medical Microbiology and Infectious Diseases, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    J Clin Microbiol 44:1555-7. 2006
    ..7% of carriage-associated isolates versus 52.9% of invasive isolates; P = 0.03). Multilocus sequence typing revealed that successful staphylococcal clones usually harbor the egc locus...
  15. doi request reprint Reclassification of Staphylococcus aureus nasal carriage types
    Alex van Belkum
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands
    J Infect Dis 199:1820-6. 2009
    ..This study was performed to provide additional insight into staphylococcal carriage types...
  16. doi request reprint Eradication of methicillin-resistant Staphylococcus aureus carriage: a systematic review
    Heidi S M Ammerlaan
    Department of Medical Microbiology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Clin Infect Dis 48:922-30. 2009
    ..aureus carriage, with an estimated success of rate of 90% 1 week after treatment and approximately 60% after a longer follow-up period...
  17. doi request reprint Low carriage rate of group B streptococcus in pregnant women in Maputo, Mozambique
    Florentien D O de Steenwinkel
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Trop Med Int Health 13:427-9. 2008
    ..GBS was cultured from 2 out of 113 samples, yielding a prevalence of 1.8% (95% Cl: 0.0-4.0). In conclusion, the prevalence of GBS carriage among pregnant women in Maputo, Mozambique was low...