Research Topics
Species | Hester F LingsmaSummaryAffiliation: Erasmus MC Country: The Netherlands Publications
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Detail Information
Publications
Incorporating natural variation into IVF clinic league tables: The Expected RankHester F Lingsma
Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
BMC Med Res Methodol 9:53. 2009..The aim of this study is to compare standard methods for ranking with a novel method that takes into account natural variation...
Prognosis in moderate and severe traumatic brain injury: external validation of the IMPACT models and the role of extracranial injuriesHester Lingsma
Departments of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands
J Trauma Acute Care Surg 74:639-46. 2013..We aimed to validate the International Mission on Prognosis and Analysis of Clinical Trials in TBI (IMPACT) prognostic models in a recent unselected patient cohort and to assess the additional prognostic value of extracranial injury...- The added value of ordinal analysis in clinical trials: an example in traumatic brain injuryBob Roozenbeek
Department of Neurosurgery, Antwerp University Hospital, Wilrijkstraat 10, Edegem, Belgium
Crit Care 15:R127. 2011..The objective of this study is to quantify the benefits of ordinal analysis in the real-life situation of a large TBI trial... - Between-centre differences and treatment effects in randomized controlled trials: a case study in traumatic brain injuryHester F Lingsma
Department of Public Health, Erasmus MC, P, O, Box 2040, 3000 CA Rotterdam, The Netherlands
Trials 12:201. 2011..The aim of this study was to assess the influence of between-centre differences in outcome on the estimated treatment effect in a large RCT in TBI... - Variation between hospitals in patient outcome after stroke is only partly explained by differences in quality of care: results from the Netherlands Stroke SurveyH F Lingsma
Department of Cardiology, Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands
J Neurol Neurosurg Psychiatry 79:888-94. 2008..The aim of this study is to investigate whether there is a straightforward relationship between quality of care and outcome, and whether outcome measures could be used to assess quality of care after stroke... - Large between-center differences in outcome after moderate and severe traumatic brain injury in the international mission on prognosis and clinical trial design in traumatic brain injury (IMPACT) studyHester F Lingsma
Erasmus Medical Center, Department of Public Health, Rotterdam, The Netherlands
Neurosurgery 68:601-7; discussion 607-8. 2011..Differences between centers in patient outcome after traumatic brain injury are of importance for multicenter studies and have seldom been studied... - Statin treatment after a recent TIA or stroke: is effectiveness shown in randomized clinical trials also observed in everyday clinical practice?H F Lingsma
Department of Public Health, Erasmus Medical Centre, Rotterdam, The Netherlands
Acta Neurol Scand 122:15-20. 2010.... - Comparing and ranking hospitals based on outcome: results from The Netherlands Stroke SurveyH F Lingsma
Department of Public Health, Erasmus MC, CA Rotterdam, The Netherlands
QJM 103:99-108. 2010..Measuring quality of care and ranking hospitals with outcome measures poses two major methodological challenges: case-mix adjustment and variation that exists by chance... 
Baseline characteristics and statistical power in randomized controlled trials: selection, prognostic targeting, or covariate adjustment?Bob Roozenbeek
Department of Public Health, Center for Medical Decision Making, Erasmus MC, Rotterdam, The Netherlands
Crit Care Med 37:2683-90. 2009..We aimed to investigate the potential benefits of different approaches for dealing with heterogeneity in a case study on traumatic brain injury (TBI)...- Prediction of outcome after moderate and severe traumatic brain injury: external validation of the International Mission on Prognosis and Analysis of Clinical Trials (IMPACT) and Corticoid Randomisation After Significant Head injury (CRASH) prognostic modBob Roozenbeek
Department of Public Health, Center for Medical Decision Making, Erasmus MC, Rotterdam, The Netherlands
Crit Care Med 40:1609-17. 2012.... - Remarkable changes in the choice of timing to discuss organ donation with the relatives of a patient: a study in 228 organ donations in 20 yearsYorick J de Groot
Department of Intensive Care, Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Crit Care 15:R235. 2011..Second, we investigated how thorough the process of brain death determination was over time by studying the number of medical specialists involved. And we studied the possible influence of the Donor Register on the consent rate... - Long-term prognosis of aphasia after strokeHanane El Hachioui
Department of Neurology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands
J Neurol Neurosurg Psychiatry 84:310-5. 2013..This observational prospective study was aimed at predicting functional outcome at 1 year after stroke... - The influence of enrollment criteria on recruitment and outcome distribution in traumatic brain injury studies: results from the impact studyBob Roozenbeek
Department of Public Health, Center for Medical Decision Making, Rotterdam, The Netherlands
J Neurotrauma 26:1069-75. 2009..The use of strict enrollment criteria leads to substantial reductions in the recruitment of RCTs in TBI. The outcome in TBI studies depends strongly on the enrollment criteria... - Prognostic value of major extracranial injury in traumatic brain injury: an individual patient data meta-analysis in 39,274 patientsNikki van Leeuwen
Center for Medical Decision Making, Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands
Neurosurgery 70:811-8; discussion 818. 2012..Major extracranial injury (MEI) is common in traumatic brain injury (TBI) patients, but the effect on outcome is controversial... - Early prognosis in traumatic brain injury: from prophecies to predictionsHester F Lingsma
Centre for Medical Decision Making, Department of Public Health, Erasmus University Medical Centre, Rotterdam, The Netherlands
Lancet Neurol 9:543-54. 2010..Continued development, refinement, and validation is advocated, together with assessment of the clinical impact of prediction models, including treatment response... - Predicting 14-day mortality after severe traumatic brain injury: application of the IMPACT models in the brain trauma foundation TBI-trac® New York State databaseBob Roozenbeek
Department of Public Health, Center for Medical Decision Making, Erasmus MC, Rotterdam, The Netherlands
J Neurotrauma 29:1306-12. 2012..79 (Core) and 0.83 (Extended). We conclude that the IMPACT models validly predict 14-day mortality in the BTF database, confirming generalizability of these models for outcome prediction in TBI patients... - External validation of a prognostic model predicting time of death after withdrawal of life support in neurocritical patientsYorick J de Groot
Department of Intensive Care, Center for Medical Decision Making, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
Crit Care Med 40:233-8. 2012..We aimed to externally validate a previously developed model to predict the probability of death within the time constraint of 60 mins after withdrawal of life-sustaining measures... - [Performance indicators: the role of 'task uncertainty']Anne Margreet van Dishoeck
Erasmus MC, afd Maatschappelijke Gezondheidszorg, Rotterdam, The Netherlands
Ned Tijdschr Geneeskd 154:A1775. 2010..The participation of health care professionals in the development of quality indicators is, therefore, very important... - Random variation and rankability of hospitals using outcome indicatorsAnne Margreet van Dishoeck
Department of Public Health, Center for Medical Decision Making, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherland
BMJ Qual Saf 20:869-74. 2011..Subsequently, the rankability was calculated by relating heterogeneity to uncertainty within and between hospitals (τ(2)/(τ(2) +median σ(2)))... - Early recognition of poor prognosis in Guillain-Barre syndromeC Walgaard
Department of Neurology, Erasmus MC, University Medical Centre, 3000 CA Rotterdam, The Netherlands
Neurology 76:968-75. 2011..We developed a clinical prognostic model for early prediction of outcome in GBS, applicable for clinical practice and future therapeutic trials... - Prediction of 60 day case-fatality after aneurysmal subarachnoid haemorrhage: results from the International Subarachnoid Aneurysm Trial (ISAT)R Risselada
Department of Medical Informatics, Erasmus MC, room Ee 2159, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
Eur J Epidemiol 25:261-6. 2010.... - Process of care partly explains the variation in mortality between hospitals after peripheral vascular surgeryS E Hoeks
Department of Anesthesiology, Erasmus Medical Center, Rotterdam, The Netherlands
Eur J Vasc Endovasc Surg 40:147-54. 2010..The aim of this study is to investigate whether variation in mortality at hospital level reflects differences in quality of care of peripheral vascular surgery patients... - Clinical factors associated with outcome in chronic subdural hematoma: a retrospective cohort study of patients on preoperative corticosteroid therapyLotte M E Berghauser Pont
Department of Neurosurgery, Erasmus University Medical Center, Rotterdam, The Netherlands
Neurosurgery 70:873-80; discussion 880. 2012..Chronic subdural hematoma (CSDH) is commonly seen in neurosurgical practice, and the incidence is increasing. Treatment results are highly variable with respect to recurrences and complications... - Logistic random effects regression models: a comparison of statistical packages for binary and ordinal outcomesBaoyue Li
Department of Biostatistics, Erasmus MC, Dr, Molewaterplein 50, Rotterdam, The Netherlands
BMC Med Res Methodol 11:77. 2011..Logistic random effects models are a popular tool to analyze multilevel also called hierarchical data with a binary or ordinal outcome. Here, we aim to compare different statistical software implementations of these models... - Promoting thrombolysis in acute ischemic strokeMaaike Dirks
Erasmus MC University Hospital Rotterdam, Department of Neurology, and Institute for Health Policy and Management, Erasmus University Rotterdam, Room H 673, PO Box 2040, 3000 CA Rotterdam, The Netherlands
Stroke 42:1325-30. 2011.... - Risk and epidemiological time trends of gastric cancer in Lynch syndrome carriers in the NetherlandsLisette G Capelle
Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
Gastroenterology 138:487-92. 2010..The aim of this study was to evaluate incidence trends and risk of developing gastric cancer among Lynch syndrome mutation carriers in a Western population... - Fibroblast growth factor receptor 3 mutation analysis on voided urine for surveillance of patients with low-grade non-muscle-invasive bladder cancerTahlita C M Zuiverloon
Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands
Clin Cancer Res 16:3011-8. 2010..We aim to determine the potential of FGFR3 mutation analysis on voided urine to detect recurrences during surveillance of patients with low-grade NMI-BC... - Prediction of respiratory insufficiency in Guillain-Barré syndromeChrista Walgaard
Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
Ann Neurol 67:781-7. 2010..We aimed to develop a simple but accurate model to predict the chance of respiratory insufficiency in the acute stage of the disease based on clinical characteristics available at hospital admission... - Recovery of aphasia after stroke: a 1-year follow-up studyHanane El Hachioui
Department of Neurology, Erasmus MC University Medical Center, Room EE 2291, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
J Neurol 260:166-71. 2013..The improvement of verbal communication continues after the stabilization of the recovery of the linguistic components... - Assessing the incremental value of diagnostic and prognostic markers: a review and illustrationEwout W Steyerberg
Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
Eur J Clin Invest 42:216-28. 2012..New markers may improve prediction of diagnostic and prognostic outcomes. We review various measures to quantify the incremental value of markers over standard, readily available characteristics... - Prediction of major vascular events in patients with transient ischemic attack or ischemic stroke: a comparison of 7 modelsAnnemarie D Wijnhoud
Departments of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
Stroke 41:2178-85. 2010..In patients with a recent TIA or minor stroke, prediction of long-term risk of major vascular events is important, but difficult. We aimed to study the external validity of currently available prediction models... - Biomarker-based prediction of inflammatory bowel disease-related colorectal cancer: a case-control studyMonique M Gerrits
Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
Cell Oncol (Dordr) 34:107-17. 2011..Screening accuracy may increase by using a biomarker-based surveillance strategy... - Predicting asthma in preschool children with asthma symptoms: study rationale and designEsther Hafkamp-de Groen
The Generation R Study Group, Erasmus MC, Rotterdam, The Netherlands
BMC Pulm Med 12:65. 2012.... - Prediction of two month modified Rankin Scale with an ordinal prediction model in patients with aneurysmal subarachnoid haemorrhageRoelof Risselada
Department of Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
BMC Med Res Methodol 10:86. 2010..Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating event with a frequently disabling outcome. Our aim was to develop a prognostic model to predict an ordinal clinical outcome at two months in patients with aSAH... - Donor conversion rates depend on the assessment tools used in the evaluation of potential organ donorsYorick J de Groot
Department of Intensive Care, Erasmus MC University Medical Center, Rotterdam, The Netherlands
Intensive Care Med 37:665-70. 2011..Our aim was to determine which assessment tool can be used for a realistic estimation of a POD pool and how they compare to each other with regard to DCR...