P J Koudstaal

Summary

Affiliation: Erasmus Medical Center
Country: The Netherlands

Publications

  1. pmc PISA. The effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute stroke: protocol for a phase II double-blind randomised placebo-controlled trial [ISRCTN98608690]
    Eric J van Breda
    Department of Neurology, University Hospital Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    BMC Cardiovasc Disord 2:7. 2002
  2. ncbi request reprint Controlled safety study of a hemoglobin-based oxygen carrier, DCLHb, in acute ischemic stroke
    R Saxena
    Department of Neurology, University Hospital Dijkzigt, Rotterdam, The Netherlands
    Stroke 30:993-6. 1999
  3. ncbi request reprint Unrecognized myocardial infarction and the risk of stroke: the Rotterdam Study
    M A Ikram
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands
    Neurology 67:1635-9. 2006
  4. ncbi request reprint Coagulation and fibrinolysis markers and risk of dementia. The Dutch Vascular Factors in Dementia Study
    M L Bots
    Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands
    Haemostasis 28:216-22. 1998
  5. ncbi request reprint Long-term occurrence of death and cardiovascular events in patients with transient ischaemic attack or minor ischaemic stroke: comparison between arterial and cardiac source of the index event
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 79:895-9. 2008
  6. ncbi request reprint Response to activated protein C in subjects with and without dementia. The Dutch Vascular Factors in Dementia Study
    M L Bots
    Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands
    Haemostasis 28:209-15. 1998
  7. ncbi request reprint Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe
    T den Heijer
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 64:263-7. 2005
  8. doi request reprint Risk indicators for development of headache during dipyridamole treatment after cerebral ischaemia of arterial origin
    P H A Halkes
    Department of Neurology, Rudolf Magnus Institute of Neuroscience and Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 80:437-9. 2009
  9. pmc Mental status and health-related quality of life in an elderly population 15 years after limited cerebral ischaemia
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol 254:1018-25. 2007
  10. doi request reprint Genetic determinants of von Willebrand factor plasma levels and the risk of stroke: the Rotterdam Study
    M C VAN Schie
    Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Thromb Haemost 10:550-6. 2012

Collaborators

Detail Information

Publications59

  1. pmc PISA. The effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute stroke: protocol for a phase II double-blind randomised placebo-controlled trial [ISRCTN98608690]
    Eric J van Breda
    Department of Neurology, University Hospital Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    BMC Cardiovasc Disord 2:7. 2002
    ..The study results will be analysed on an intent-to-treat basis, but an on-treatment analysis will also be performed. No formal interim analysis will be carried out...
  2. ncbi request reprint Controlled safety study of a hemoglobin-based oxygen carrier, DCLHb, in acute ischemic stroke
    R Saxena
    Department of Neurology, University Hospital Dijkzigt, Rotterdam, The Netherlands
    Stroke 30:993-6. 1999
    ..In animal stroke models its use led to a significant reduction in the extent of brain injury. The primary objective of this study was to evaluate the safety of DCLHb in patients with acute ischemic stroke...
  3. ncbi request reprint Unrecognized myocardial infarction and the risk of stroke: the Rotterdam Study
    M A Ikram
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands
    Neurology 67:1635-9. 2006
    ..To investigate the relationship between unrecognized myocardial infarction and the risk of stroke in a population-based cohort study...
  4. ncbi request reprint Coagulation and fibrinolysis markers and risk of dementia. The Dutch Vascular Factors in Dementia Study
    M L Bots
    Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands
    Haemostasis 28:216-22. 1998
    ..Additional stratified analyses indicated that an increased TAT level was the primary factor related to dementia. The present study provides evidence that predominantly increased thrombin generation is associated with dementia...
  5. ncbi request reprint Long-term occurrence of death and cardiovascular events in patients with transient ischaemic attack or minor ischaemic stroke: comparison between arterial and cardiac source of the index event
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 79:895-9. 2008
    ..Data on long term risks are scarce. We compared the long term risks of death and vascular events (VE) between these groups...
  6. ncbi request reprint Response to activated protein C in subjects with and without dementia. The Dutch Vascular Factors in Dementia Study
    M L Bots
    Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands
    Haemostasis 28:209-15. 1998
    ..82-5.63), respectively. No association was found for APC response. We showed a nonsignificant twofold increased risk of dementia among subjects with factor V Leiden. The association appeared to be stronger for vascular dementia...
  7. ncbi request reprint Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe
    T den Heijer
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 64:263-7. 2005
    ..Alternatively, in persons with high blood pressure, increased numbers of neurofibrillary tangles and amyloid plaques at autopsy have also been observed, suggesting direct links between blood pressure and AD...
  8. doi request reprint Risk indicators for development of headache during dipyridamole treatment after cerebral ischaemia of arterial origin
    P H A Halkes
    Department of Neurology, Rudolf Magnus Institute of Neuroscience and Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 80:437-9. 2009
    ..63 (95% CI 0.58 to 0.68)) and in ESPS 2 with female sex and absence of ischaemic lesions on imaging (area under the ROC curve 0.64 (95% CI 0.59 to 0.69))...
  9. pmc Mental status and health-related quality of life in an elderly population 15 years after limited cerebral ischaemia
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol 254:1018-25. 2007
    ..Our study was designed to describe the mental status and health-related quality of life (HRQoL) in long-term survivors of TIA or minor ischaemic stroke (MIS) and evaluate associations of mental and physical factors with HR-QoL...
  10. doi request reprint Genetic determinants of von Willebrand factor plasma levels and the risk of stroke: the Rotterdam Study
    M C VAN Schie
    Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Thromb Haemost 10:550-6. 2012
    ..Whether these SNPs are associated with stroke risk is not known. The aim of our study was to investigate the association between genetic determinants of VWF levels and stroke risk...
  11. ncbi request reprint Dietary folate, vitamin B12, and vitamin B6 and the risk of Parkinson disease
    L M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 67:315-8. 2006
    ..Moreover, vitamin B6 might influence the risk of PD through antioxidant effects unrelated to homocysteine metabolism and through its role in dopamine synthesis...
  12. ncbi request reprint Risk of early death and recurrent stroke and effect of heparin in 3169 patients with acute ischemic stroke and atrial fibrillation in the International Stroke Trial
    R Saxena
    Department of Neurology, University Hospital Dijkzigt, Rotterdam, Netherlands
    Stroke 32:2333-7. 2001
    ....
  13. doi request reprint Tiotropium Handihaler and the risk of cardio- or cerebrovascular events and mortality in patients with COPD
    K M C Verhamme
    Department of Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    Pulm Pharmacol Ther 25:19-26. 2012
    ..Recent data from RCTs suggests tiotropium Handihaler to be safe, but its safety has not yet been fully investigated under real-life circumstances...
  14. doi request reprint Effects of high-dose paracetamol on blood pressure in acute stroke
    H M den Hertog
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Acta Neurol Scand 125:265-71. 2012
    ..Besides its antipyretic effects, paracetamol may affect blood pressure through cyclooxygenase-2 inhibition. We therefore aimed to assess the effect of high-dose paracetamol on blood pressure in patients with acute stroke...
  15. doi request reprint Is dementia incidence declining?: Trends in dementia incidence since 1990 in the Rotterdam Study
    E M C Schrijvers
    Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Neurology 78:1456-63. 2012
    ..To investigate whether dementia incidence has changed over the last 2 decades...
  16. ncbi request reprint The CAMCOG: a useful screening instrument for dementia in stroke patients
    I de Koning
    Department of Neurology, University Hospital Rotterdam Dijkzigt, Rotterdam, The Netherlands
    Stroke 29:2080-6. 1998
    ..BACKGROUND and..
  17. ncbi request reprint Retinal vessel diameters and risk of stroke: the Rotterdam Study
    M K Ikram
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 66:1339-43. 2006
    ..A smaller ratio of the retinal arteriolar-to-venular diameters reportedly predicts the risk of stroke. It is unclear if this is due to arteriolar narrowing or venular dilation...
  18. pmc Retinal vascular caliber and risk of dementia: the Rotterdam study
    F J De Jong
    Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Neurology 76:816-21. 2011
    ..Whether retinal vessel calibers are related to dementia remains unclear...
  19. doi request reprint Duration of antihypertensive drug use and risk of dementia: A prospective cohort study
    M D M Haag
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 72:1727-34. 2009
    ..Duration of follow-up was limited and relied mainly on baseline drug exposure data without information on duration of use. We investigated the association between the duration of antihypertensive use and risk of dementia...
  20. ncbi request reprint Effect of paracetamol (acetaminophen) on body temperature in acute ischemic stroke: a double-blind, randomized phase II clinical trial
    D W Dippel
    Department of Neurology, University Hospital Rotterdam, Rotterdam, The Netherlands
    Stroke 32:1607-12. 2001
    ..The main purpose of this trial was to study whether early treatment of acute ischemic stroke patients with acetaminophen (paracetamol) reduces body temperature...
  21. ncbi request reprint Is carotid intima-media thickness useful in cardiovascular disease risk assessment? The Rotterdam Study
    A I del Sol
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Stroke 32:1532-8. 2001
    ..We determined the contribution of common carotid intima-media thickness (IMT) in the prediction of future coronary heart disease and cerebrovascular disease when added to established risk factors...
  22. ncbi request reprint Increased platelet activation in the chronic phase after cerebral ischemia and intracerebral hemorrhage
    F van Kooten
    Department of Neurology, University Hospital Rotterdam, The Netherlands
    Stroke 30:546-9. 1999
    ..We investigated whether enhanced urinary excretion of 11-dehydro-TXB2, a noninvasive index of platelet activation, was present in the chronic phase after a transient ischemic attack (TIA) or stroke, including intracerebral hemorrhage...
  23. ncbi request reprint Effect of diaspirin cross-linked hemoglobin on endothelin-1 and blood pressure in acute ischemic stroke in man
    R Saxena
    Department of Neurology, University Hospital Dijkzigt, Rotterdam, The Netherlands
    J Hypertens 16:1459-65. 1998
    ..We investigated the involvement of endothelin-1 in the blood pressure response to the oxygen carrier diaspirin cross-linked hemoglobin (DCLHb) in stroke patients...
  24. doi request reprint Fibrinogen γ' levels in patients with intracerebral hemorrhage
    E G van den Herik
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Thromb Res 129:807-9. 2012
    ..The fibrinogen γ' variant (γ') has both antithrombotic and prothrombotic properties when compared to normal fibrinogen. It may therefore be of relevance in intracerebral hemorrhage and intraventricular extension of the bleeding...
  25. ncbi request reprint Dietary fatty acids and the risk of Parkinson disease: the Rotterdam study
    L M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 64:2040-5. 2005
    ..Unsaturated fatty acids are important constituents of neuronal cell membranes and have neuroprotective, antioxidant, and anti-inflammatory properties...
  26. pmc Functional status and use of healthcare facilities in long-term survivors of transient ischaemic attack or minor ischaemic stroke
    I van Wijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 77:1238-43. 2006
    ..Stroke may have a major effect on survivors and on the healthcare system...
  27. ncbi request reprint The diagnostic value of colour duplex ultrasound for symptomatic carotid stenosis in clinical practice
    D W Dippel
    Dept of Neurology, University Hospital Dijkzigt, Rotterdam, The Netherlands
    Neuroradiology 41:1-8. 1999
    ..Its use as a single preoperative assessment cannot be recommended...
  28. ncbi request reprint Role of platelet activation in dementia
    F van Kooten
    Department of Neurology, University Hospital Rotterdam, The Netherlands
    Haemostasis 28:202-8. 1998
    ..Furthermore, the efficacy and safety of antiplatelet intervention will have to be assessed in properly designed randomized trials...
  29. doi request reprint The prognostic value of pulsatility index, flow velocity, and their ratio, measured with TCD ultrasound, in patients with a recent TIA or ischemic stroke
    A D Wijnhoud
    Department of Neurology, Erasmus Medical Center Rotterdam, The Netherlands
    Acta Neurol Scand 124:238-44. 2011
    ..2 (95% CI: 1.3-3.6) for major vascular events. CONCLUSION - In patients with a TIA or non-disabling ischemic stroke, MFV and the PI-MFV ratio in the MCA are independent prognostic factors for recurrent vascular events...
  30. doi request reprint Structural and diffusion MRI measures of the hippocampus and memory performance
    T den Heijer
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Neuroimage 63:1782-9. 2012
    ..Follow-up studies will be needed to determine whether higher MD of hippocampus at younger ages could be an earlier marker of incident Alzheimer's disease than hippocampal volume...
  31. doi request reprint Impact of early surgery after aneurysmal subarachnoid haemorrhage
    M van der Jagt
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Acta Neurol Scand 119:100-6. 2009
    ..To investigate the effect of early aneurysm surgery (<72 h) on outcome in patients with subarachnoid haemorrhage (SAH)...
  32. doi request reprint Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study
    M D M Haag
    Department of Epidemiology, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 80:13-7. 2009
    ..Prospective studies have provided inconsistent evidence. Moreover, it is unclear whether the association differs for lipophilic statins, those that could more easily pass the blood-brain barrier and hydrophilic statins...
  33. ncbi request reprint The validity and reliability of signs of early infarction on CT in acute ischaemic stroke
    D W Dippel
    Department of Neurology, University Hospital Rotterdam, The Netherlands
    Neuroradiology 42:629-33. 2000
    ....
  34. ncbi request reprint Spinal dural arteriovenous fistulas are not associated with prothrombotic factors
    K Jellema
    Department of Neurology, St Elisabeth Hospital Tilburg, The Netherlands
    Stroke 35:2069-71. 2004
    ..In intracranial dural arteriovenous fistulas, an association with factor V Leiden mutation has been found. Therefore, we studied the association between prothrombotic factors and SDAVF...
  35. ncbi request reprint Increased thromboxane biosynthesis is associated with poststroke dementia
    F van Kooten
    Department of Neurology, University Hospital Rotterdam, Rotterdam, The Netherlands
    Stroke 30:1542-7. 1999
    ..We have therefore studied the relationship between thromboxane (TX) A(2) biosynthesis, as reflected by the urinary excretion of 11-dehydro-TXB(2), and the presence of dementia in patients after acute stroke...
  36. ncbi request reprint Value of screening instruments in the diagnosis of post-stroke dementia
    I de Koning
    Department of Neurology, University Hospital Rotterdam Dijkzigt, Rotterdam, The Netherlands
    Haemostasis 28:158-66. 1998
    ..With the growing interest in research for vascular factors in dementia over the past years, however, a specific screening instrument for post-stroke dementia would be a valuable contribution...
  37. ncbi request reprint Epidemiology of post-stroke dementia
    F van Kooten
    Department of Neurology, University Hospital Rotterdam Dijkzigt, Rotterdam, The Netherlands
    Haemostasis 28:124-33. 1998
    ..Finally, the course and prognosis of post-stroke dementia are described...
  38. pmc C-reactive protein in the very early phase of acute ischemic stroke: association with poor outcome and death
    H M den Hertog
    Department of Neurology, Erasmus MC University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Neurol 256:2003-8. 2009
    ..7, 95% CI 1.0–2.9) at 3 months. In addition, the risk of poor outcome or death at 3 months increased with higher levels of CRP. CRP within 12 h of ischemic stroke is an independent prognostic factor of poor outcome at 3 months...
  39. ncbi request reprint Severity of cerebral white matter lesions and infarcts in patients with transient or moderately disabling cerebral ischaemia: reproducibility of grading by neurologists
    E L L M De Schryver
    Department of Neurology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Eur J Neurol 13:901-3. 2006
    ..Such assessment may prevent unnecessary risk with oral anticoagulation in secondary prevention after cerebral ischaemia of arterial origin, of which the efficacy is currently being assessed in ESPRIT...
  40. ncbi request reprint Incidence of parkinsonism and Parkinson disease in a general population: the Rotterdam Study
    L M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 63:1240-4. 2004
    ..To investigate the incidence of parkinsonism and Parkinson disease (PD) in the general population using in-person screening along with clinical data...
  41. ncbi request reprint MR spectroscopy of brain white matter in the prediction of dementia
    T den Heijer
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Neurology 66:540-4. 2006
    ..Given the long prodromal period of Alzheimer disease (AD), the authors sought to investigate whether biochemical changes can be observed also in the preclinical period...
  42. doi request reprint The Paracetamol (Acetaminophen) In Stroke (PAIS) trial: a multicentre, randomised, placebo-controlled, phase III trial
    Heleen M den Hertog
    Department of Neurology, Erasmus MC University Medical Centre, Rotterdam, Netherlands
    Lancet Neurol 8:434-40. 2009
    ..The Paracetamol (Acetaminophen) In Stroke (PAIS) trial aimed to assess whether early treatment with paracetamol improves functional outcome in patients with acute stroke by reducing body temperature and preventing fever...
  43. ncbi request reprint Timing of the effect of acetaminophen on body temperature in patients with acute ischemic stroke
    D W J Dippel
    Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 61:677-9. 2003
    ..26 degrees C (95% CI 0.07 to 0.46 degrees C) lower mean body temperature than placebo treatment within 4 hours. This effect remained present throughout the next 20 hours. A large phase III trial seems warranted...
  44. ncbi request reprint The impact of APOE on myocardial infarction, stroke, and dementia: the Rotterdam Study
    A J C Slooter
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 62:1196-8. 2004
    ..8% higher. Risk estimates of dementia, specified for age, sex, and APOE, are provided for counseling. APOE is not strongly related to vascular diseases, but contributes substantially to dementia incidence...
  45. ncbi request reprint Thoracic radicular vessels by simultaneous intra-arterial and intravenous injection of araldite
    K Jellema
    Department of Neurology, St Elisabeth Hospital, Tilburg, The Netherlands
    Clin Anat 20:524-9. 2007
    ..We found a total of six thoracic arteriovenous shunts in four cadavers but their role in the pathogenesis of SDAVF remains uncertain. No vascular anatomic differences between men and women were found...
  46. ncbi request reprint Do antiphospholipid antibodies increase the long-term risk of thrombotic complications in young patients with a recent TIA or ischemic stroke?
    M P J van Goor
    Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Acta Neurol Scand 109:410-5. 2004
    ..The purpose of our study was to determine the relative risk of thrombotic events in young patients with a recent TIA or ischemic stroke and positive antiphospholipid antibodies (aPL)...
  47. ncbi request reprint Effects of an individualized multimedia computer program for health education in patients with a recent minor stroke or transient ischemic attack - a randomized controlled trial
    E Maasland
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Acta Neurol Scand 115:41-8. 2007
    ..We developed a computer program that provided health education fitting the educational level, risk profile and symptoms of patients and evaluated it in a randomized controlled trial...
  48. ncbi request reprint Measuring progression of cerebral white matter lesions on MRI: visual rating and volumetrics
    N D Prins
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 62:1533-9. 2004
    ..To evaluate the concordance of a volumetric method for measuring white matter lesion (WML) change with visual rating scales...
  49. pmc Diagnostic value of the Rotterdam-CAMCOG in post-stroke dementia
    I de Koning
    Department of Neurology, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 76:263-5. 2005
    ..In this study, we externally validated the diagnostic accuracy of the R-CAMCOG in a new, representative cohort of stroke patients...
  50. ncbi request reprint Spinal dural arteriovenous fistulas: long-term follow-up of 44 treated patients
    K Jellema
    Department of Neurology, St Elisabeth Hospital Tilburg, The Netherlands
    Neurology 62:1839-41. 2004
    ..In most patients, gait disturbances and muscle strength had improved after treatment, with reduced disability; problems with micturition, defecation, and erection tended to remain unchanged...
  51. ncbi request reprint Cerebral CO2 reactivity, cholesterol, and high-density lipoprotein cholesterol in the elderly
    S L Bakker
    Department of Neurology, University Hospital Rotterdam, The Netherlands
    Neurology 54:987-9. 2000
    ..Cerebral CO2 reactivity increased significantly with increasing levels of HDL and decreased significantly with an increasing total cholesterol/HDL ratio. This suggests that blood lipids may also affect smaller cerebral blood vessels...
  52. ncbi request reprint Cerebral hemodynamics before and after shunting in normal pressure hydrocephalus
    S L M Bakker
    Department of Neurology, Erasmus MC, Rotterdam, The Netherlands
    Acta Neurol Scand 106:123-7. 2002
    ..To study the relationship between cerebral hemodynamics and clinical performance in normal pressure hydrocephalus (NPH), before and after surgery...
  53. ncbi request reprint Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI
    T den Heijer
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Dr Molewaterplein 50, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
    Diabetologia 46:1604-10. 2003
    ..We investigated the association between diabetes mellitus, insulin resistance and the degree of hippocampal and amygdalar atrophy on magnetic resonance imaging (MRI) accounting for vascular pathology...
  54. ncbi request reprint Anticoagulation in atrial fibrillation and flutter
    M F Scholten
    Department of Clinical Electrophysiology, Thoraxcentre, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Europace 7:492-9. 2005
    ..A strategy for anticoagulation around the time of pulmonary vein ablation is suggested...
  55. doi request reprint Efficacy of early cognitive-linguistic treatment and communicative treatment in aphasia after stroke: a randomised controlled trial (RATS-2)
    M de Jong-Hagelstein
    Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 82:399-404. 2011
    ..The hypothesis that CLT is more effective than communicative treatment in the early stages after stroke was tested in this study...
  56. doi request reprint Is isolated aphasia a typical presentation of presumed cardioembolic transient ischemic attack or stroke?
    Th F M Fennis
    Department of Neurology, Ziekenhuis St Jansdal, Harderwijk, The Netherlands
    Cerebrovasc Dis 35:337-40. 2013
    ..The purpose of this study was to assess the relationship between isolated aphasia and atrial fibrillation (AF) as the cause of presumed cardioembolic TIA or stroke within the setting of 2 large multicenter trials...
  57. ncbi request reprint Elevated prothrombin is a risk factor for cerebral arterial ischemia in young adults
    E B Gomez Garcia
    Department of Hematology, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Clin Neurol Neurosurg 104:285-8. 2002
    ..We conclude that, although PT 20210A may be a weak risk factor for TIA and ischemic stroke in young patients, increased PT activity, which is more frequent than the mutation, appears to be more strongly related to cerebral ischemia...
  58. pmc Incidence, risk, and case fatality of first ever stroke in the elderly population. The Rotterdam Study
    M Hollander
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 74:317-21. 2003
    ..To estimate the incidence, survival, and lifetime risk of stroke in the elderly population...
  59. pmc Cerebral haemodynamics and depression in the elderly
    H Tiemeier
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre Rotterdam, Rotterdam, Netherlands
    J Neurol Neurosurg Psychiatry 73:34-9. 2002
    ....