Markus Klimek

Summary

Affiliation: Erasmus MC Rotterdam
Location: Rotterdam, Netherlands
Summary:
Vice-Chairman / Vice-Head Residency Training Program
Depts. of Anesthesiology and Emergency medicine

Chairman Medical Incident Committee Erasmus MC
Chairman Dutch Society of Neuroanesthesiology
Editor in Chief Dutch Anesthesia Journal

Fields of interest:
Awake brain surgery
Patient safety and comfort

Publications

  1. ncbi The influence of various anesthetics on the release and metabolism of thyroid hormones: results of two clinical studies
    U Borner
    Department of Anesthesiology, Medical Faculty, University of Cologne, Germany
    Anesth Analg 81:612-8. 1995
  2. ncbi Reversal of rocuronium-induced (1.2 mg kg-1) profound neuromuscular block by accidental high dose of sugammadex (40 mg kg-1)
    A L Molina
    Department of Anaesthesiology, Erasmus University Medical Centre, Rotterdam, and Martini Hospital Groningen, The Netherlands
    Br J Anaesth 98:624-7. 2007
  3. ncbi Reversal of rocuronium-induced (1.2 mg/kg) profound neuromuscular block by sugammadex: a multicenter, dose-finding and safety study
    Hans D de Boer
    Department of Anesthesiology, Radboud University Medical Center Nijmegen, The Netherlands
    Anesthesiology 107:239-44. 2007
  4. doi B and T cell imbalances in CSF of patients with Hu-antibody associated PNS
    Marieke de Graaf
    Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Neuroimmunol 195:164-70. 2008
  5. ncbi [Perioperative care for the older patient]
    E Blommers
    Erasmus MC Centrum, afd Anesthesiologie, H 12 Noord, Postbus 2040, 3000 CA Rotterdam
    Ned Tijdschr Geneeskd 152:1513-7. 2008
  6. doi Protocol compliance and time management in blunt trauma resuscitation
    W R Spanjersberg
    Erasmus MC, University Medical Center Rotterdam, Department of Surgery Traumatology, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Emerg Med J 26:23-7. 2009
  7. doi Train-of-four ratio recovery often precedes twitch recovery when neuromuscular block is reversed by sugammadex
    L M Staals
    Department of Anaesthesiology, Erasmus University Medical Centre, Sophia Children s Hospital, Rotterdam, The Netherlands
    Acta Anaesthesiol Scand 55:700-7. 2011
  8. doi Perioperative care of the older patient
    E Blommers
    Department of Anesthesiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Z Gerontol Geriatr 44:187-91. 2011
  9. doi A randomised study of perioperative esmolol infusion for haemodynamic stability during major vascular surgery; rationale and design of DECREASE-XIII
    E J Bakker
    Department of Anesthesiology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 42:317-23. 2011
  10. ncbi [Physostigmine for the immediate treatment of a patient with the central anticholinergic syndrome induced by cocaine cut with atropine]
    W P Ridder
    Erasmus MC, afd Anesthesiologie, Dr Molewaterplein 40, 3015 GD, Rotterdam
    Ned Tijdschr Geneeskd 149:1701-3. 2005

Collaborators

Detail Information

Publications26

  1. ncbi The influence of various anesthetics on the release and metabolism of thyroid hormones: results of two clinical studies
    U Borner
    Department of Anesthesiology, Medical Faculty, University of Cologne, Germany
    Anesth Analg 81:612-8. 1995
    ..Hence we assume the increase to be due to hormone release from thyroid and/or extrathyroidal stores--an intercompartmental shifting...
  2. ncbi Reversal of rocuronium-induced (1.2 mg kg-1) profound neuromuscular block by accidental high dose of sugammadex (40 mg kg-1)
    A L Molina
    Department of Anaesthesiology, Erasmus University Medical Centre, Rotterdam, and Martini Hospital Groningen, The Netherlands
    Br J Anaesth 98:624-7. 2007
    ..2 mg kg-1) profound neuromuscular block. A fast and efficient recovery from profound neuromuscular block was achieved and no adverse events or other safety concerns were reported...
  3. ncbi Reversal of rocuronium-induced (1.2 mg/kg) profound neuromuscular block by sugammadex: a multicenter, dose-finding and safety study
    Hans D de Boer
    Department of Anesthesiology, Radboud University Medical Center Nijmegen, The Netherlands
    Anesthesiology 107:239-44. 2007
    ..This study investigated the efficacy and safety of sugammadex in reversing rocuronium-induced profound neuromuscular blockade at 5 min in American Society of Anesthesiologists physical status I and II patients...
  4. doi B and T cell imbalances in CSF of patients with Hu-antibody associated PNS
    Marieke de Graaf
    Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Neuroimmunol 195:164-70. 2008
    ..In addition, the autoimmune hypothesis of Hu-PNS is supported by the relative NKT cell deficiency...
  5. ncbi [Perioperative care for the older patient]
    E Blommers
    Erasmus MC Centrum, afd Anesthesiologie, H 12 Noord, Postbus 2040, 3000 CA Rotterdam
    Ned Tijdschr Geneeskd 152:1513-7. 2008
    ..Recent developments focus on multimodal perioperative care of the older patient to shorten hospital stay, using minimal invasive surgery, postoperative anaesthesiology rounds and early geriatric consultation...
  6. doi Protocol compliance and time management in blunt trauma resuscitation
    W R Spanjersberg
    Erasmus MC, University Medical Center Rotterdam, Department of Surgery Traumatology, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Emerg Med J 26:23-7. 2009
    ....
  7. doi Train-of-four ratio recovery often precedes twitch recovery when neuromuscular block is reversed by sugammadex
    L M Staals
    Department of Anaesthesiology, Erasmus University Medical Centre, Sophia Children s Hospital, Rotterdam, The Netherlands
    Acta Anaesthesiol Scand 55:700-7. 2011
    ..9. The recovery time of T1 was not described. This retrospective investigation describes the recovery of T1 vs. TOF ratio after the reversal of NMB with sugammadex...
  8. doi Perioperative care of the older patient
    E Blommers
    Department of Anesthesiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Z Gerontol Geriatr 44:187-91. 2011
    ..Recent developments focus on multimodal perioperative care of the older patient, using minimally invasive surgery, postoperative anesthesiology rounds, and early geriatric consultation...
  9. doi A randomised study of perioperative esmolol infusion for haemodynamic stability during major vascular surgery; rationale and design of DECREASE-XIII
    E J Bakker
    Department of Anesthesiology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 42:317-23. 2011
    ....
  10. ncbi [Physostigmine for the immediate treatment of a patient with the central anticholinergic syndrome induced by cocaine cut with atropine]
    W P Ridder
    Erasmus MC, afd Anesthesiologie, Dr Molewaterplein 40, 3015 GD, Rotterdam
    Ned Tijdschr Geneeskd 149:1701-3. 2005
    ..In the presence of indications for such an intoxication, physostigmine is the antidote of first choice...
  11. ncbi Trends but not individual values of central venous oxygen saturation agree with mixed venous oxygen saturation during varying hemodynamic conditions
    Michael H Dueck
    Department of Anesthesiology, University of Cologne, Cologne, Germany
    Anesthesiology 103:249-57. 2005
    ..The inconsistency of study results may result from different study designs and different, partly questionable, statistical approaches...
  12. ncbi A survey of autologous blood transfusion practices in Germany
    J Kaufmann
    Department of Anaesthesiology, University of Cologne, Germany
    Transfus Med 14:335-41. 2004
    ..The use of PABD did not change significantly, the use of haemodilution declined markedly and the use of peri-operative cell salvage increased markedly during the past 5 years before the survey...
  13. ncbi [Early extubation following intracranial procedures: contra]
    U Borner
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Universitat, Koln
    Anasthesiol Intensivmed Notfallmed Schmerzther 33:336-7. 1998
  14. ncbi Does an analysis of exhaled air indicate the metabolic state of critically ill patients?
    U Borner
    Intensive Care Med 24:403-4. 1998
  15. ncbi Efficacy of oral iron supplementation is not enhanced by additional intravenous iron during autologous blood donation
    S M Kasper
    Department of Anesthesiology, University of Cologne, Germany
    Transfusion 38:764-70. 1998
    ....
  16. ncbi Postoperative analgesia with no motor block by continuous epidural infusion of ropivacaine 0.1% and sufentanil after total hip replacement
    S Kampe
    Department of Anesthesiology, University of Cologne, Germany
    Anesth Analg 89:395-8. 1999
    ..1% in treating pain after hip replacement. We found that ropivacaine 0.1% and sufentanil 1 microgram/mL led to a sixfold reduction in opioid requirements after total hip replacement by producing a negligible motor block...
  17. ncbi Surgery of intrinsic cerebral neoplasms in eloquent areas under local anesthesia
    H Ebel
    Department of Neurosurgery, University of Cologne, Germany
    Minim Invasive Neurosurg 43:192-6. 2000
    ....
  18. ncbi [A cerebral watershed infarction after general anaesthesia in a patient with increased anti-cardiolipin antibody level]
    S J C Verbrugge
    Afdeling Anesthesiologie, Erasmus MC, Rotterdam, Netherlands
    Anaesthesist 53:341-6. 2004
    ..Patients with increased anti-cardiolipin antibody levels and who suffer from epileptic attacks have an increased risk of thromboembolic events...
  19. ncbi Awake craniotomy for glioblastoma in a 9-year-old child
    M Klimek
    Department of Anaesthesiology, Erasmus MC, University Medical Centre, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Anaesthesia 59:607-9. 2004
    ..We believe that it is the individual level of development of the child that determines suitability for this type of surgery...
  20. doi A simulation model for determining the optimal size of emergency teams on call in the operating room at night
    Jeroen M van Oostrum
    Department of Operating Rooms, Erasmus University Medical Center, Room NH 4A, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Anesth Analg 107:1655-62. 2008
    ..We developed a process to determine the optimal OR team composition during the night, such that staffing costs are minimized, while providing adequate resources to start surgery within the safety interval...
  21. doi Awake craniotomy induces fewer changes in the plasma amino acid profile than craniotomy under general anesthesia
    Jaap W Hol
    Department of Anesthesiology, Erasmus MC, Rotterdam, The Netherlands
    J Neurosurg Anesthesiol 21:98-107. 2009
    ..62 days; P=0.012. This study demonstrates that awake craniotomy is likely to be physically and emotionally less stressful than general anesthesia and that amino acid profiling holds promise for monitoring postoperative pain and recovery...
  22. pmc Inflammatory profile of awake function-controlled craniotomy and craniotomy under general anesthesia
    Markus Klimek
    Department of Anesthesiology, Erasmus MC, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Mediators Inflamm 2009:670480. 2009
    ..Awake craniotomy and craniotomy performed under general anesthesia may be associated with different levels of stress. Our aim was to investigate whether those procedures cause different inflammatory responses...
  23. doi Antiepileptic drug therapy in the perioperative course of neurosurgical patients
    Markus Klimek
    Department of Anesthesiology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
    Curr Opin Anaesthesiol 23:564-7. 2010
    ..However, the evidence supporting their use is extremely small and adverse events are common. This review highlights the current controversies...
  24. ncbi Can the laryngeal mask airway replace endotracheal tubation for airway control? The argument against the laryngeal mask airway
    Markus Klimek
    Centre Location, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Isr Med Assoc J 6:242-4; discussion 244-5. 2004
  25. ncbi Pain in neurosurgically treated patients: a prospective observational study
    Markus Klimek
    Department of Anesthesiology, Erasmus University Medical Centre Rotterdam, The Netherlands
    J Neurosurg 104:350-9. 2006
    ..This is the first observational study to compare perioperative pain character and intensity in patients undergoing different types of elective neurosurgical procedures...
  26. doi [Awake craniotomy for brain tumor resection - what does the anaesthesist do?]
    Markus Klimek
    Kliniken für Anästhesiologie und Notfallmedizin am Erasmus MC, Universitätsklinikum Rotterdam, Niederlande
    Anasthesiol Intensivmed Notfallmed Schmerzther 46:386-91. 2011
    ..This article describes the anaesthesiological management at Erasmus MC, University Medical Centre Rotterdam, The Netherlands, in detail...