Rogier Kersseboom

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi request reprint Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement
    Rogier Kersseboom
    Department of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Immunol 176:4543-52. 2006
  2. doi request reprint PTEN in colorectal cancer: a report on two Cowden syndrome patients
    R Kersseboom
    Department of Clinical Genetics, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Clin Genet 81:555-62. 2012
  3. pmc Educational paper: syndromic forms of primary immunodeficiency
    Rogier Kersseboom
    Department of Clinical Genetics, Room Ee2014, Erasmus MC Rotterdam, P O Box 2040, NL 3000 CA Rotterdam, The Netherlands
    Eur J Pediatr 170:295-308. 2011
  4. ncbi request reprint Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity
    Sabine Middendorp
    Department of Immunology, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Blood 105:259-65. 2005
  5. ncbi request reprint Involvement of SLP-65 and Btk in tumor suppression and malignant transformation of pre-B cells
    Rudi W Hendriks
    Department of Immunology, Erasmus MC Rotterdam, P O Box 1738, NL 3000 DR Rotterdam, The Netherlands
    Semin Immunol 18:67-76. 2006
  6. doi request reprint Malignant transformation of Slp65-deficient pre-B cells involves disruption of the Arf-Mdm2-p53 tumor suppressor pathway
    Van B T Ta
    Department of Immunology, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Blood 115:1385-93. 2010
  7. doi request reprint Constitutive activation of Bruton's tyrosine kinase induces the formation of autoreactive IgM plasma cells
    Rogier Kersseboom
    Department of Immunology, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Eur J Immunol 40:2643-54. 2010

Collaborators

  • Rudi W Hendriks
  • H Jumaa
  • Van B T Ta
  • Sabine Middendorp
  • Pieter Fokko Van Loo
  • Petra J ter Brugge
  • Hans J A Diepstraten
  • Marjolein J W de Bruijn
  • Jan Piet van Hamburg
  • A J Esther Zijlstra
  • Gemma M Dingjan

Detail Information

Publications7

  1. ncbi request reprint Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement
    Rogier Kersseboom
    Department of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Immunol 176:4543-52. 2006
    ..These findings demonstrate that Btk and SLP-65 transmit signals that induce cellular maturation and Ig L chain rearrangement independently of their role in termination of pre-B cell expansion...
  2. doi request reprint PTEN in colorectal cancer: a report on two Cowden syndrome patients
    R Kersseboom
    Department of Clinical Genetics, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Clin Genet 81:555-62. 2012
    ..Prospective follow-up and surveillance of PTEN mutation carriers from the age of 25 to 30 years in a study setting should clarify this issue...
  3. pmc Educational paper: syndromic forms of primary immunodeficiency
    Rogier Kersseboom
    Department of Clinical Genetics, Room Ee2014, Erasmus MC Rotterdam, P O Box 2040, NL 3000 CA Rotterdam, The Netherlands
    Eur J Pediatr 170:295-308. 2011
    ..This paper provides the general pediatrician with the main clinical features that are crucial for the recognition of these syndromes...
  4. ncbi request reprint Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity
    Sabine Middendorp
    Department of Immunology, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Blood 105:259-65. 2005
    ..Therefore, we conclude that Btk exerts its tumor suppressor function in pre-B cells as an adaptor protein, independent of its catalytic activity...
  5. ncbi request reprint Involvement of SLP-65 and Btk in tumor suppression and malignant transformation of pre-B cells
    Rudi W Hendriks
    Department of Immunology, Erasmus MC Rotterdam, P O Box 1738, NL 3000 DR Rotterdam, The Netherlands
    Semin Immunol 18:67-76. 2006
    ..As a result, activated Btk transmits survival signals that are essential for the transforming activity of oncogenic Abl tyrosine kinase...
  6. doi request reprint Malignant transformation of Slp65-deficient pre-B cells involves disruption of the Arf-Mdm2-p53 tumor suppressor pathway
    Van B T Ta
    Department of Immunology, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Blood 115:1385-93. 2010
    ..These data indicate that malignant transformation of Slp65(-/-) pre-B cells involves disruption of the p19(Arf)-Mdm2-p53 tumor suppressor pathway...
  7. doi request reprint Constitutive activation of Bruton's tyrosine kinase induces the formation of autoreactive IgM plasma cells
    Rogier Kersseboom
    Department of Immunology, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Eur J Immunol 40:2643-54. 2010
    ....