Research Topics
| Stijn KeereweerSummaryAffiliation: Erasmus MC Country: The Netherlands Publications
| Collaborators
|
Detail Information
Publications
Detection of oral squamous cell carcinoma and cervical lymph node metastasis using activatable near-infrared fluorescence agentsStijn Keereweer
Department of Otorhinolaryngology Head and Neck Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
Arch Otolaryngol Head Neck Surg 137:609-15. 2011..To assess the feasibility of optical imaging using activatable near-infrared fluorescence (NIRF) agents to detect oral cancer and cervical lymph node metastasis in vivo...
Optical imaging of oral squamous cell carcinoma and cervical lymph node metastasisStijn Keereweer
Erasmus Medical Center, Department of Otorhinolaryngology Head and Neck Surgery, Rotterdam, The Netherlands
Head Neck 34:1002-8. 2012..In oral cancer surgery, intraoperative optical imaging could help the surgeon to determine adequate tumor-free margins...
Subglottic stenosis in Shwachman-Diamond syndrome - is there a link?S Keereweer
Department of Otorhinolaryngology, Sophia Children s Hospital, Erasmus Medical Center, Rotterdam, The Netherlands
Int J Pediatr Otorhinolaryngol 76:1531-2. 2012..Otorhinolaryngologist and paediatricians should be aware of the risk of airway pathology in patients with SDS...
Dual wavelength tumor targeting for detection of hypopharyngeal cancer using near-infrared optical imaging in an animal modelStijn Keereweer
Department of Otorhinolaryngology Head and Neck Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
Int J Cancer 131:1633-40. 2012..NIR fluorescence optical imaging has the potential to be translated into the clinic in order to improve the complete removal of tumors by real-time image-guided surgery...
Targeting integrins and enhanced permeability and retention (EPR) effect for optical imaging of oral cancerStijn Keereweer
Erasmus Medical Center, Department of Otorhinolaryngology Head and Neck Surgery, Rotterdam, The Netherlands
J Surg Oncol 105:714-8. 2012..We assessed the feasibility of cancer detection using NIR fluorescence agents that target either αvβ3 integrins or the enhanced permeability and retention (EPR) effect in an orthotopic mouse model of oral cancer...
Chemoradiation for advanced hypopharyngeal carcinoma: a retrospective study on efficacy, morbidity and quality of lifeStijn Keereweer
Department of Otorhinolaryngology Head and Neck Surgery, Erasmus University Medical Center, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
Eur Arch Otorhinolaryngol 269:939-46. 2012..However, significant acute and long-term toxic effects occur, and organ preservation appears not necessarily equivalent to preservation of function and better QOL...
Chronic serous otitis media as a manifestation of temporal meningiomaS Keereweer
Department of Otorhinolaryngology, Head and Neck Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
ORL J Otorhinolaryngol Relat Spec 73:287-90. 2011..The CSF leakage was closed by surgery. Histopathology confirmed meningioma in the temporal bone...
Image-guided surgery in head and neck cancer: current practice and future directions of optical imagingS Keereweer
Department of Otorhinolaryngology Head and Neck Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
Head Neck 34:120-6. 2012....
Optical image-guided surgery--where do we stand?Stijn Keereweer
Department of Otorhinolaryngology, Head and Neck Surgery, Erasmus Medical Center, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
Mol Imaging Biol 13:199-207. 2011..Furthermore, we provide an overview of the wide range of molecular contrast agents targeting specific hallmarks of cancer and we describe perspectives on its future use in cancer surgery...
Early and long-term morbidity after total laryngopharyngectomyStijn Keereweer
Department of Head and Neck Surgery, Erasmus University Medical Center, Daniel den Hoed Cancer Center, 301 Groene Hilledijk, 3075 EA, Rotterdam, The Netherlands
Eur Arch Otorhinolaryngol 267:1437-44. 2010..Complete oral intake was achieved in 97%, and speech rehabilitation in 95%. These procedures are associated with significant morbidity, high complication rates, lengthy rehabilitation, but a good long-term quality of life...
Dysphagia after an L-shaped reconstruction technique of the free jejunum graftS Keereweer
Department of Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
J Plast Reconstr Aesthet Surg 63:1820-4. 2010..However, besides necrosis of the jejunum graft, the two most important complications are pharyngocutaneous fistula formation and dysphagia due to stricture formation...
Dual-wavelength imaging of tumor progression by activatable and targeting near-infrared fluorescent probes in a bioluminescent breast cancer modelBang Wen Xie
Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands
PLoS ONE 7:e31875. 2012..This study may open up new perspectives for the detection of tumors and metastases in various experimental models and could also have clinical applications, such as image-guided surgery...
Translational optical imaging in diagnosis and treatment of cancerStijn Keereweer
Erasmus Medical Center, Department of Otorhinolaryngology Head and Neck Surgery, Rotterdam, The Netherlands
Curr Pharm Biotechnol 13:498-503. 2012..Widespread availability of imaging systems and optical contrast agents will enable larger studies on their clinical benefit and can help establish a definitive role in clinical practice...
