Mariette H W Kappers

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi request reprint Paraganglioma of the urinary bladder
    M H W Kappers
    Department of Internal Medicine, Ikazia Hospital, Rotterdam, The Netherlands
    Neth J Med 66:163-5. 2008
  2. doi request reprint Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels
    Mariette H W Kappers
    Division of Pharmacology, Vascular and Metabolic Diseases, Department of Internal Medicine, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Hypertension 56:675-81. 2010
  3. doi request reprint The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system
    Mariette H W Kappers
    Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Hypertension 58:295-302. 2011
  4. doi request reprint Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression
    Mariette H W Kappers
    Division of Pharmacology, Department of Internal Medicine, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
    J Clin Endocrinol Metab 96:3087-94. 2011
  5. doi request reprint Sunitinib-induced systemic vasoconstriction in swine is endothelin mediated and does not involve nitric oxide or oxidative stress
    Mariette H W Kappers
    Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Hypertension 59:151-7. 2012
  6. doi request reprint Mechanism of hypertension and proteinuria during angiogenesis inhibition: evolving role of endothelin-1
    Stephanie Lankhorst
    Department of Internal Medicine, Pharmacology and Vascular Medicine, Erasmus MC, Rotterdam, The Netherlands
    J Hypertens 31:444-54; discussion 454. 2013
  7. doi request reprint Hypertension during vascular endothelial growth factor inhibition: focus on nitric oxide, endothelin-1, and oxidative stress
    Stephanie Lankhorst
    Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    Antioxid Redox Signal 20:135-45. 2014
  8. ncbi request reprint [New insights into the pathogenesis of pre-eclampsia: the role of angiogenesis-inhibiting factors]
    Koen Verdonk
    Erasmus Medisch Centrum, Rotterdam, The Netherlands
    Ned Tijdschr Geneeskd 155:A2946. 2011
  9. doi request reprint Light-induced vs. bradykinin-induced relaxation of coronary arteries: do S-nitrosothiols act as endothelium-derived hyperpolarizing factors?
    Wendy W Batenburg
    Department of Internal Medicine, Division of Pharmacology, Vascular and Metabolic Diseases, Erasmus Medical Center, Rotterdam 3015 GE, The Netherlands
    J Hypertens 27:1631-40. 2009

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Paraganglioma of the urinary bladder
    M H W Kappers
    Department of Internal Medicine, Ikazia Hospital, Rotterdam, The Netherlands
    Neth J Med 66:163-5. 2008
    ..Although the patient presented with classical signs and symptoms, these were only appreciated after histological examination of a transurethral resection specimen had elucidated the correct diagnosis...
  2. doi request reprint Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels
    Mariette H W Kappers
    Division of Pharmacology, Vascular and Metabolic Diseases, Department of Internal Medicine, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Hypertension 56:675-81. 2010
    ..In conclusion, sunitinib induces a reversible rise in BP in patients and in rats associated with activation of the endothelin-1 system, suppression of the renin-angiotensin system, and generalized microvascular dysfunction...
  3. doi request reprint The vascular endothelial growth factor receptor inhibitor sunitinib causes a preeclampsia-like syndrome with activation of the endothelin system
    Mariette H W Kappers
    Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Hypertension 58:295-302. 2011
    ....
  4. doi request reprint Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression
    Mariette H W Kappers
    Division of Pharmacology, Department of Internal Medicine, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
    J Clin Endocrinol Metab 96:3087-94. 2011
    ..Anticancer treatment with the tyrosine kinase inhibitor sunitinib causes thyroid dysfunction...
  5. doi request reprint Sunitinib-induced systemic vasoconstriction in swine is endothelin mediated and does not involve nitric oxide or oxidative stress
    Mariette H W Kappers
    Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Hypertension 59:151-7. 2012
    ..The sunitinib-mediated systemic hypertension is principally attributed to an increased vasoconstrictor influence of endothelin, with no apparent contributions of a loss of NO bioavailability or increased oxidative stress...
  6. doi request reprint Mechanism of hypertension and proteinuria during angiogenesis inhibition: evolving role of endothelin-1
    Stephanie Lankhorst
    Department of Internal Medicine, Pharmacology and Vascular Medicine, Erasmus MC, Rotterdam, The Netherlands
    J Hypertens 31:444-54; discussion 454. 2013
    ....
  7. doi request reprint Hypertension during vascular endothelial growth factor inhibition: focus on nitric oxide, endothelin-1, and oxidative stress
    Stephanie Lankhorst
    Division of Pharmacology and Vascular Medicine, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    Antioxid Redox Signal 20:135-45. 2014
    ..Antioxid. Redox Signal. 20, 135-145. ..
  8. ncbi request reprint [New insights into the pathogenesis of pre-eclampsia: the role of angiogenesis-inhibiting factors]
    Koen Verdonk
    Erasmus Medisch Centrum, Rotterdam, The Netherlands
    Ned Tijdschr Geneeskd 155:A2946. 2011
    ..Whether elevations in the plasma concentrations of sFlt and sEng, combined with a decrease in placental growth factor concentrations, can be utilised as a predictor for pre-eclampsia is currently under investigation...
  9. doi request reprint Light-induced vs. bradykinin-induced relaxation of coronary arteries: do S-nitrosothiols act as endothelium-derived hyperpolarizing factors?
    Wendy W Batenburg
    Department of Internal Medicine, Division of Pharmacology, Vascular and Metabolic Diseases, Erasmus Medical Center, Rotterdam 3015 GE, The Netherlands
    J Hypertens 27:1631-40. 2009
    ..Here we compared the mechanism of light-induced and bradykinin-induced PCA relaxation...