Wendy E Kaman
Affiliation: Erasmus MC
Country: The Netherlands
- Peptide-based fluorescence resonance energy transfer protease substrates for the detection and diagnosis of Bacillus speciesWendy E Kaman
Department of Medical Microbiology and Infectious Diseases, Erasmus MC, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
Anal Chem 83:2511-7. 2011..anthracis spores and diagnosis of anthrax infection is at hand. We are the first who present fluorogenic substrates for detection of bacterial proteolytic enzymes that can be directly applied in situ by the use of D-oriented amino acids...
- A comprehensive study on the role of the Yersinia pestis virulence markers in an animal model of pneumonic plagueW E Kaman
TNO Defence, Security and Safety, 2280 AA, Rijswijk, The Netherlands
Folia Microbiol (Praha) 56:95-102. 2011..We can conclude that all known virulence genes are required for the establishment of pneumonic plague in mammalian animal models, the role of HmsF being of particular importance in disease progression...
- Highly specific protease-based approach for detection of porphyromonas gingivalis in diagnosis of periodontitisWendy E Kaman
Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands
J Clin Microbiol 50:104-12. 2012..We envisage that these substrates may improve the specificity of the current enzyme-based diagnosis of periodontitis associated with P. gingivalis...
- Activation of Toll-like receptors and dendritic cells by a broad range of bacterial moleculesLinda C L Boele
TNO Defence, Security and Safety, Business Unit Biological and Chemical Protection, Detection and Identification, PO Box 45, 2280AA Rijswijk, The Netherlands
Cell Immunol 255:17-25. 2009..Taken together, this study provides insight into qualitative differences and general effects of pathogen-derived molecules on dendritic cells...
- The bradykinin B2 receptor in the early immune response against Listeria infectionWendy E Kaman
TNO Defence, Security and Safety, Business Unit Biological and Chemical Protection, 2280 AA, Rijswijk, The Netherlands
Med Microbiol Immunol 198:39-46. 2009..Thus, we show that bradykinin and the B(2)R play a role in early innate immune functions during bacterial infection...