E H Jacobs

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi request reprint Active heroin administration induces specific genomic responses in the nucleus accumbens shell
    Edwin H Jacobs
    Research Institute Neurosciences Vrije Universiteit, Drug Abuse Program, Department of Medical Pharmacology, VU Medical Center, 1081 BT Amsterdam, The Netherlands
    FASEB J 16:1961-3. 2002
  2. ncbi request reprint Neuroadaptive effects of active versus passive drug administration in addiction research
    Edwin H Jacobs
    Research Institute Neurosciences Vrije Universiteit, Drug Abuse Program, Department of Medical Pharmacology, VU Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Trends Pharmacol Sci 24:566-73. 2003
  3. ncbi request reprint Long-term gene expression in the nucleus accumbens following heroin administration is subregion-specific and depends on the nature of drug administration
    Edwin H Jacobs
    Department of Medical Pharmacology, Research Institute Neurosciences, VU Medical Center, Vrije Universiteit, Amsterdam, The Netherlands
    Addict Biol 10:91-100. 2005
  4. ncbi request reprint Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease
    E H Jacobs
    Wolfson Centre for Age Related Diseases, Guy s, King s and St Thomas Schools of Biomedical Sciences, King s College London, St Thomas Street, London SE1 1UL, UK
    Neuroscience 138:511-22. 2006
  5. ncbi request reprint Gene transcripts selectively down-regulated in the shell of the nucleus accumbens long after heroin self-administration are up-regulated in the core independent of response contingency
    Edwin H Jacobs
    Research Institute Neurosciences Vrije Universiteit, Department of Medical Pharmacology, VU Medical Center, Amsterdam, The Netherlands
    FASEB J 18:200-2. 2004
  6. ncbi request reprint Morphine causes a delayed increase in glutamate receptor functioning in the nucleus accumbens core
    Edwin H Jacobs
    Research Institute Neurosciences Vrije Universiteit, Drug Abuse Program, Department of Medical Pharmacology, Free University Medical Center, VUMC, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Eur J Pharmacol 511:27-30. 2005

Detail Information

Publications6

  1. ncbi request reprint Active heroin administration induces specific genomic responses in the nucleus accumbens shell
    Edwin H Jacobs
    Research Institute Neurosciences Vrije Universiteit, Drug Abuse Program, Department of Medical Pharmacology, VU Medical Center, 1081 BT Amsterdam, The Netherlands
    FASEB J 16:1961-3. 2002
    ..This work reveals that active drug consumption during self-administration (instrumental learning) is a crucial psychological factor directing long-term genomic responses in the brain...
  2. ncbi request reprint Neuroadaptive effects of active versus passive drug administration in addiction research
    Edwin H Jacobs
    Research Institute Neurosciences Vrije Universiteit, Drug Abuse Program, Department of Medical Pharmacology, VU Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Trends Pharmacol Sci 24:566-73. 2003
    ..e. passive (non-contingent) drug exposure and active (contingent) self-administration]. This has important ramifications for future molecular and cellular studies of drug addiction...
  3. ncbi request reprint Long-term gene expression in the nucleus accumbens following heroin administration is subregion-specific and depends on the nature of drug administration
    Edwin H Jacobs
    Department of Medical Pharmacology, Research Institute Neurosciences, VU Medical Center, Vrije Universiteit, Amsterdam, The Netherlands
    Addict Biol 10:91-100. 2005
    ....
  4. ncbi request reprint Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease
    E H Jacobs
    Wolfson Centre for Age Related Diseases, Guy s, King s and St Thomas Schools of Biomedical Sciences, King s College London, St Thomas Street, London SE1 1UL, UK
    Neuroscience 138:511-22. 2006
    ....
  5. ncbi request reprint Gene transcripts selectively down-regulated in the shell of the nucleus accumbens long after heroin self-administration are up-regulated in the core independent of response contingency
    Edwin H Jacobs
    Research Institute Neurosciences Vrije Universiteit, Department of Medical Pharmacology, VU Medical Center, Amsterdam, The Netherlands
    FASEB J 18:200-2. 2004
    ....
  6. ncbi request reprint Morphine causes a delayed increase in glutamate receptor functioning in the nucleus accumbens core
    Edwin H Jacobs
    Research Institute Neurosciences Vrije Universiteit, Drug Abuse Program, Department of Medical Pharmacology, Free University Medical Center, VUMC, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Eur J Pharmacol 511:27-30. 2005
    ..These data reveal that morphine may progressively enhance glutamate neurotransmission within the nucleus accumbens core subsequent to drug exposure...