B C Jacobs


Affiliation: Erasmus MC
Country: The Netherlands


  1. Jacobs B, Koga M, van Rijs W, Geleijns K, van Doorn P, Willison H, et al. Subclass IgG to motor gangliosides related to infection and clinical course in Guillain-Barré syndrome. J Neuroimmunol. 2008;194:181-90 pubmed publisher
    ..These findings support a model in which C. jejuni and H. influenzae infections induce two distinct patterns of cross-reactive antibodies with different clinical outcome. ..
  2. Meyer Sauteur P, Huizinga R, Tio Gillen A, Roodbol J, Hoogenboezem T, Jacobs E, et al. Mycoplasma pneumoniae triggering the Guillain-Barré syndrome: A case-control study. Ann Neurol. 2016;80:566-80 pubmed publisher
    ..006). M. pneumoniae infection is associated with GBS, more frequently in children than adults, and elicits anti-GalC antibodies, of which specifically anti-GalC IgG may contribute to the pathogenesis of GBS. Ann Neurol 2016;80:566-580. ..
  3. Roodbol J, de Wit M, van den Berg B, Kahlmann V, Drenthen J, Catsman Berrevoets C, et al. Diagnosis of Guillain-Barré syndrome in children and validation of the Brighton criteria. J Neurol. 2017;264:856-861 pubmed publisher
    ..The majority of the pediatric GBS patients presented in this cohort fulfilled the current diagnostic criteria. ..
  4. Kahlmann V, Roodbol J, van Leeuwen N, Ramakers C, Van Pelt D, Neuteboom R, et al. Validated age-specific reference values for CSF total protein levels in children. Eur J Paediatr Neurol. 2017;21:654-660 pubmed publisher
    ..More accurate age-specific reference values for CSF total protein levels in children were determined. These new reference values are more sensitive than currently used values for diagnosing GBS and ADEM in children. ..
  5. Meyer Sauteur P, Huizinga R, Tio Gillen A, Drenthen J, Unger W, Jacobs E, et al. Intrathecal antibody responses to GalC in Guillain-Barré syndrome triggered by Mycoplasma pneumoniae. J Neuroimmunol. 2018;314:13-16 pubmed publisher
    ..Intrathecal anti-GalC IgG was specifically associated with Mp-GBS, further supporting that anti-GalC IgG contributes to the pathogenesis of GBS. ..
  6. van den Berg B, Fokke C, Drenthen J, van Doorn P, Jacobs B. Paraparetic Guillain-Barré syndrome. Neurology. 2014;82:1984-9 pubmed publisher
    ..To define the clinical and diagnostic characteristics of paraparetic Guillain-Barré syndrome (GBS) with weakness restricted to the legs, compared with the classic quadriparetic GBS...