Andre T Hoogeveen

Summary

Affiliation: Erasmus University
Country: The Netherlands

Publications

  1. ncbi Fragile X syndrome, the Fragile X related proteins, and animal models
    Andre T Hoogeveen
    Department of Clinical Genetics, Erasmus University, 3000 DR Rotterdam, The Netherlands
    Microsc Res Tech 57:148-55. 2002
  2. ncbi The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies
    Andre T Hoogeveen
    Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands
    Oncogene 21:6703-12. 2002
  3. ncbi Prospects of TAT-mediated protein therapy for fragile X syndrome
    Surya A Reis
    CBG Department of Clinical Genetics, Erasmus MC, 3000 DR Rotterdam, The Netherlands
    J Mol Histol 35:389-95. 2004
  4. ncbi Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo
    Edwin J Mientjes
    Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands
    Hum Mol Genet 13:1291-302. 2004
  5. ncbi Loss of FMR1 hypermethylation in somatic cell heterokaryons
    Violeta Stoyanova
    Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
    FASEB J 18:1964-6. 2004
  6. ncbi The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome
    Rob Willemsen
    CBG Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
    Hum Mol Genet 12:949-59. 2003
  7. ncbi Knockout mouse model for Fxr2: a model for mental retardation
    Carola J M Bontekoe
    CBG Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands
    Hum Mol Genet 11:487-98. 2002

Collaborators

Detail Information

Publications7

  1. ncbi Fragile X syndrome, the Fragile X related proteins, and animal models
    Andre T Hoogeveen
    Department of Clinical Genetics, Erasmus University, 3000 DR Rotterdam, The Netherlands
    Microsc Res Tech 57:148-55. 2002
    ..Phenotypic features of the FMR1 knockout mouse, the FMR1 transgenic rescue mouse, and other novel strategies for manipulating and delivering FMRP and FXRPs to the brain and other tissues are described...
  2. ncbi The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies
    Andre T Hoogeveen
    Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands
    Oncogene 21:6703-12. 2002
    ..The deficiency of HDAC-containing complexes at nucleolar sites and the accumulation of HDAC-containing complexes at AML1-sites may be critical in the pathogenesis of t (16; 21) myeloid malignancies...
  3. ncbi Prospects of TAT-mediated protein therapy for fragile X syndrome
    Surya A Reis
    CBG Department of Clinical Genetics, Erasmus MC, 3000 DR Rotterdam, The Netherlands
    J Mol Histol 35:389-95. 2004
    ..However, uptake efficiency and velocity was lower than expected. Neuronal uptake was highly inefficient and the fusion protein demonstrated toxicity...
  4. ncbi Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo
    Edwin J Mientjes
    Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands
    Hum Mol Genet 13:1291-302. 2004
    ..The results presented here point towards a role for Fxr1p in muscle mRNA transport/translation control similar to that seen for Fmrp in neuronal cells...
  5. ncbi Loss of FMR1 hypermethylation in somatic cell heterokaryons
    Violeta Stoyanova
    Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
    FASEB J 18:1964-6. 2004
    ..In contrast, demethylation was not observed when cells from unrelated individuals with fragile X syndrome were fused, indicating that FX cells have lost the necessary factor(s) to demethylate the aberrantly methylated FMR1 promoter...
  6. ncbi The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome
    Rob Willemsen
    CBG Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
    Hum Mol Genet 12:949-59. 2003
    ..This mouse model will facilitate the possibilities to perform studies at the molecular level from onset of symptoms until the final stage of the disease...
  7. ncbi Knockout mouse model for Fxr2: a model for mental retardation
    Carola J M Bontekoe
    CBG Department of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands
    Hum Mol Genet 11:487-98. 2002
    ..The findings implicate a role for Fxr2 in central nervous system function...