Genomes and Genes
Affiliation: Erasmus MC
Country: The Netherlands
- Hofland J, Van Weerden W, Dits N, Steenbergen J, van Leenders G, Jenster G, et al. Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer. Cancer Res. 2010;70:1256-64 pubmed publisher....
- Hofland J, Feelders R, van der Wal R, Kerstens M, Haak H, de Herder W, et al. Serum inhibin pro-?C is a tumor marker for adrenocortical carcinomas. Eur J Endocrinol. 2012;166:281-9 pubmed publisher..0065). Inhibin pro-?C is produced by the adrenal gland. Differentiation between ADA and ACC by serum inhibin pro-?C is limited, but its levels may constitute a novel tumor marker for ACC. ..
- Hofland J, Delhanty P, Steenbergen J, Hofland L, van Koetsveld P, van Nederveen F, et al. Melanocortin 2 receptor-associated protein (MRAP) and MRAP2 in human adrenocortical tissues: regulation of expression and association with ACTH responsiveness. J Clin Endocrinol Metab. 2012;97:E747-54 pubmed publisher..MRAP and MC2R expression is induced by ACTH and AngII, which would facilitate cell surface receptor availability. Physiological expression levels of MRAP, MRAP2, and MC2R were not limiting for ACTH sensitivity. ..
- Snaterse G, Visser J, Arlt W, Hofland J. Circulating steroid hormone variations throughout different stages of prostate cancer. Endocr Relat Cancer. 2017;24:R403-R420 pubmed publisher..Additionally, this review addresses the implications of these findings, highlights important studies in this field and identifies current gaps in literature. ..