Rudolf W Hendriks
Affiliation: Erasmus University
Country: The Netherlands
- Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymusR W Hendriks
Department of Cell Biology and Genetics, Faculty of Medicine, Erasmus University Rotterdam, The Netherlands
Eur J Immunol 29:1912-8. 1999..We therefore propose that GATA-3 is required for the expansion of T cell progenitors, and for the control of subsequent proliferation steps, which alternate periods of TCR recombination in the thymus...
- Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouseG M Dingjan
Department of Immunology, Faculty of Medicine, Erasmus University Rotterdam, 3000 DR Rotterdam, The Netherlands
J Exp Med 193:1169-78. 2001..These results implicate Btk in the regulation of the activation of the lambda locus for V(D)J recombination in pre-B cells...
- A subfraction of B220(+) cells in murine bone marrow and spleen does not belong to the B cell lineage but has dendritic cell characteristicsTatjana Nikolic
Department of Immunology, Faculty of Medicine, Erasmus University Rotterdam, Rotterdam, The Netherlands
Eur J Immunol 32:686-92. 2002..Taken together, our findings indicate that the mouse bone marrow contains a recirculating population of B220(+)CD19(-) CD11c(+) plasmacytoid DC, the development of which is largely independent of the presence of mature T and B cells...