Research Topics
Species | Rudolf W HendriksSummaryAffiliation: Erasmus University Country: The Netherlands Publications
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Detail Information
Publications
Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymusR W Hendriks
Department of Cell Biology and Genetics, Faculty of Medicine, Erasmus University Rotterdam, The Netherlands
Eur J Immunol 29:1912-8. 1999..We therefore propose that GATA-3 is required for the expansion of T cell progenitors, and for the control of subsequent proliferation steps, which alternate periods of TCR recombination in the thymus...
Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouseG M Dingjan
Department of Immunology, Faculty of Medicine, Erasmus University Rotterdam, 3000 DR Rotterdam, The Netherlands
J Exp Med 193:1169-78. 2001..These results implicate Btk in the regulation of the activation of the lambda locus for V(D)J recombination in pre-B cells...
A subfraction of B220(+) cells in murine bone marrow and spleen does not belong to the B cell lineage but has dendritic cell characteristicsTatjana Nikolic
Department of Immunology, Faculty of Medicine, Erasmus University Rotterdam, Rotterdam, The Netherlands
Eur J Immunol 32:686-92. 2002..Taken together, our findings indicate that the mouse bone marrow contains a recirculating population of B220(+)CD19(-) CD11c(+) plasmacytoid DC, the development of which is largely independent of the presence of mature T and B cells...
