Joost P J J Hegmans

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi Proteomic analysis of exosomes secreted by human mesothelioma cells
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands
    Am J Pathol 164:1807-15. 2004
  2. ncbi Immunotherapy of murine malignant mesothelioma using tumor lysate-pulsed dendritic cells
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus MC, H Ee2253a, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Am J Respir Crit Care Med 171:1168-77. 2005
  3. ncbi Protein profiling of pleural effusions to identify malignant pleural mesothelioma using SELDI-TOF MS
    Joost P J J Hegmans
    Department of Pulmonary Medicine Erasmus MC, Dr Molewaterplein 50 3015 GE Rotterdam, The Netherlands
    Technol Cancer Res Treat 8:323-32. 2009
  4. ncbi COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function
    Joris D Veltman
    Department of Pulmonary Medicine, Erasmus MC Rotterdam, The Netherlands
    BMC Cancer 10:464. 2010
  5. ncbi Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines
    Claudia Zanazzi
    Department of Pathology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands
    Genes Chromosomes Cancer 46:895-908. 2007
  6. ncbi Low-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activity
    Joris D Veltman
    Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Biomed Biotechnol 2010:798467. 2010
  7. ncbi Exosomes
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    Methods Mol Biol 484:97-109. 2008

Collaborators

Detail Information

Publications7

  1. ncbi Proteomic analysis of exosomes secreted by human mesothelioma cells
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands
    Am J Pathol 164:1807-15. 2004
    ..Exosomes may play an important role in the interaction between tumor cells and their environment...
  2. ncbi Immunotherapy of murine malignant mesothelioma using tumor lysate-pulsed dendritic cells
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus MC, H Ee2253a, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Am J Respir Crit Care Med 171:1168-77. 2005
    ..Currently, dendritic cell-based immunotherapy is evaluated clinically in a number of malignancies, including melanoma and urogenital and lung cancer, showing variable but promising results...
  3. ncbi Protein profiling of pleural effusions to identify malignant pleural mesothelioma using SELDI-TOF MS
    Joost P J J Hegmans
    Department of Pulmonary Medicine Erasmus MC, Dr Molewaterplein 50 3015 GE Rotterdam, The Netherlands
    Technol Cancer Res Treat 8:323-32. 2009
    ..Our study validates the use of SMRP as a diagnostic marker for pleural mesothelioma and furthermore suggests that Apo CI levels could be used in the future to discriminate pleural mesothelioma from other causes of exudates...
  4. ncbi COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function
    Joris D Veltman
    Department of Pulmonary Medicine, Erasmus MC Rotterdam, The Netherlands
    BMC Cancer 10:464. 2010
    ..In addition, we determined if dietary celecoxib treatment leads to refinement of immunotherapeutic strategies...
  5. ncbi Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines
    Claudia Zanazzi
    Department of Pathology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands
    Genes Chromosomes Cancer 46:895-908. 2007
    ....
  6. ncbi Low-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activity
    Joris D Veltman
    Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Biomed Biotechnol 2010:798467. 2010
    ..Addition of cyclophosphamide improved immunotherapy leading to an increased median and overall survival. Future studies are needed to address the usefulness of this combination treatment for mesothelioma patients...
  7. ncbi Exosomes
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    Methods Mol Biol 484:97-109. 2008
    ..Although the full understanding of the significance of exosomes requires additional studies, these membrane vesicles could become a new important component in orchestrating responses between cells...