Joost P J J Hegmans

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc Patient-tailored modulation of the immune system may revolutionize future lung cancer treatment
    Marlies E Heuvers
    Department of Pulmonary Medicine, Erasmus Medical Center, Postbox 2040, 3000 CA, Rotterdam, The Netherlands
    BMC Cancer 12:580. 2012
  2. pmc Proteomic analysis of exosomes secreted by human mesothelioma cells
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands
    Am J Pathol 164:1807-15. 2004
  3. ncbi request reprint Immunotherapy of murine malignant mesothelioma using tumor lysate-pulsed dendritic cells
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus MC, H Ee2253a, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Am J Respir Crit Care Med 171:1168-77. 2005
  4. ncbi request reprint Protein profiling of pleural effusions to identify malignant pleural mesothelioma using SELDI-TOF MS
    Joost P J J Hegmans
    Department of Pulmonary Medicine Erasmus MC, Dr Molewaterplein 50 3015 GE Rotterdam, The Netherlands
    Technol Cancer Res Treat 8:323-32. 2009
  5. pmc COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function
    Joris D Veltman
    Department of Pulmonary Medicine, Erasmus MC Rotterdam, The Netherlands
    BMC Cancer 10:464. 2010
  6. doi request reprint Arginase-1 mRNA expression correlates with myeloid-derived suppressor cell levels in peripheral blood of NSCLC patients
    Marlies E Heuvers
    Department of Pulmonary Medicine, Erasmus Medical University Center, Rotterdam, The Netherlands Electronic address
    Lung Cancer 81:468-74. 2013
  7. ncbi request reprint Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines
    Claudia Zanazzi
    Department of Pathology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands
    Genes Chromosomes Cancer 46:895-908. 2007
  8. pmc Low-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activity
    Joris D Veltman
    Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Biomed Biotechnol 2010:798467. 2010
  9. doi request reprint Exosomes
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    Methods Mol Biol 484:97-109. 2008

Collaborators

Detail Information

Publications9

  1. pmc Patient-tailored modulation of the immune system may revolutionize future lung cancer treatment
    Marlies E Heuvers
    Department of Pulmonary Medicine, Erasmus Medical Center, Postbox 2040, 3000 CA, Rotterdam, The Netherlands
    BMC Cancer 12:580. 2012
    ....
  2. pmc Proteomic analysis of exosomes secreted by human mesothelioma cells
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus MC, Rotterdam, The Netherlands
    Am J Pathol 164:1807-15. 2004
    ..Exosomes may play an important role in the interaction between tumor cells and their environment...
  3. ncbi request reprint Immunotherapy of murine malignant mesothelioma using tumor lysate-pulsed dendritic cells
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus MC, H Ee2253a, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Am J Respir Crit Care Med 171:1168-77. 2005
    ..Currently, dendritic cell-based immunotherapy is evaluated clinically in a number of malignancies, including melanoma and urogenital and lung cancer, showing variable but promising results...
  4. ncbi request reprint Protein profiling of pleural effusions to identify malignant pleural mesothelioma using SELDI-TOF MS
    Joost P J J Hegmans
    Department of Pulmonary Medicine Erasmus MC, Dr Molewaterplein 50 3015 GE Rotterdam, The Netherlands
    Technol Cancer Res Treat 8:323-32. 2009
    ..Our study validates the use of SMRP as a diagnostic marker for pleural mesothelioma and furthermore suggests that Apo CI levels could be used in the future to discriminate pleural mesothelioma from other causes of exudates...
  5. pmc COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function
    Joris D Veltman
    Department of Pulmonary Medicine, Erasmus MC Rotterdam, The Netherlands
    BMC Cancer 10:464. 2010
    ..In addition, we determined if dietary celecoxib treatment leads to refinement of immunotherapeutic strategies...
  6. doi request reprint Arginase-1 mRNA expression correlates with myeloid-derived suppressor cell levels in peripheral blood of NSCLC patients
    Marlies E Heuvers
    Department of Pulmonary Medicine, Erasmus Medical University Center, Rotterdam, The Netherlands Electronic address
    Lung Cancer 81:468-74. 2013
    ..This method is therefore a useful alternative for the complex flowcytometric analysis in large multicenter patient studies. ..
  7. ncbi request reprint Gene expression profiling and gene copy-number changes in malignant mesothelioma cell lines
    Claudia Zanazzi
    Department of Pathology, Erasmus Medical Center, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands
    Genes Chromosomes Cancer 46:895-908. 2007
    ....
  8. pmc Low-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activity
    Joris D Veltman
    Department of Pulmonary Medicine, Erasmus Medical Center Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Biomed Biotechnol 2010:798467. 2010
    ..Addition of cyclophosphamide improved immunotherapy leading to an increased median and overall survival. Future studies are needed to address the usefulness of this combination treatment for mesothelioma patients...
  9. doi request reprint Exosomes
    Joost P J J Hegmans
    Department of Pulmonary Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    Methods Mol Biol 484:97-109. 2008
    ..Although the full understanding of the significance of exosomes requires additional studies, these membrane vesicles could become a new important component in orchestrating responses between cells...