Research Topics
| C GosselaarSummaryAffiliation: Erasmus MC Country: The Netherlands Publications
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Detail Information
Publications
Prevalence and characteristics of screen-detected prostate carcinomas at low prostate-specific antigen levels: aggressive or insignificant?Claartje Gosselaar
Department of Urology Screening unit for prostate cancer, Erasmus University, Rotterdam, The Netherlands
BJU Int 95:231-7. 2005..The favourable characteristics of tumours detectable at very low PSA levels seem to justify the conclusion that an unknown but sizeable proportion of the cancers found at biopsy are clinically insignificant...
The role of the digital rectal examination in subsequent screening visits in the European randomized study of screening for prostate cancer (ERSPC), RotterdamClaartje Gosselaar
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Eur Urol 54:581-8. 2008..The value of digital rectal examination (DRE) as a screening test for prostate cancer (PC) is controversial in the current prostate-specific antigen (PSA) era...
The interobserver variability of digital rectal examination in a large randomized trial for the screening of prostate cancerC Gosselaar
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Prostate 68:985-93. 2008....
Digital rectal examination and the diagnosis of prostate cancer--a study based on 8 years and three screenings within the European Randomized Study of Screening for Prostate Cancer (ERSPC), RotterdamClaartje Gosselaar
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Eur Urol 55:139-46. 2009..Evidence indicates that an abnormal digital rectal examination (DRE) is a risk factor for high-grade prostate cancer (PC)...
The value of an additional hypoechoic lesion-directed biopsy core for detecting prostate cancerClaartje Gosselaar
Department of Urology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
BJU Int 101:685-90. 2008..To determine the value of a hypoechoic lesion (HL)-directed biopsy in addition to a systematic sextant biopsy for detecting prostate cancer...
Screening for prostate cancer at low PSA range: the impact of digital rectal examination on tumor incidence and tumor characteristicsClaartje Gosselaar
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Prostate 67:154-61. 2007..To compare tumor characteristics of screen-detected prostate cancers (PCs) either by digital rectal examination (DRE) or by prostate-specific antigen (PSA) as biopsy indication at low PSA...
Screening and prostate-cancer mortality in a randomized European studyFritz H Schroder
Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands
N Engl J Med 360:1320-8. 2009..The European Randomized Study of Screening for Prostate Cancer was initiated in the early 1990s to evaluate the effect of screening with prostate-specific-antigen (PSA) testing on death rates from prostate cancer...
Metastatic disease of screen-detected prostate cancer : characteristics at diagnosisStijn Roemeling
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Cancer 107:2779-85. 2006..Risk stratification of screen-detected cancers at diagnosis has become more important for the anticipation and interpretation of changing incidence/mortality ratios...
Feasibility study of adjustment for contamination and non-compliance in a prostate cancer screening trialStijn Roemeling
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Prostate 67:1053-60. 2007..We present a feasibility study and impact simulation of a secondary analysis, which imitates a situation where all participants in the study are managed according to their random assignment...
Management and survival of screen-detected prostate cancer patients who might have been suitable for active surveillanceStijn Roemeling
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Eur Urol 50:475-82. 2006..CONCLUSION: Only three men died of prostate cancer, none of whom were on watchful waiting. Our observations provide preliminary validation of the arbitrary selection criteria for active surveillance...
Biochemical progression rates in the screen arm compared to the control arm of the Rotterdam Section of the European Randomized Study of Screening for Prostate Cancer (ERSPC)Stijn Roemeling
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Prostate 66:1076-81. 2006..This report compares the preliminary outcome of cancers detected in the screen and the control arm of its Rotterdam section, by means of biochemical progression rates...
Prevalence, treatment modalities and prognosis of familial prostate cancer in a screened populationStijn Roemeling
Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands
J Urol 175:1332-6. 2006..The clinical presentation and prognosis of familial disease remain uncertain. In this study these entities are evaluated in the first and second rounds of a screening program in The Netherlands...
Active surveillance for prostate cancers detected in three subsequent rounds of a screening trial: characteristics, PSA doubling times, and outcomeStijn Roemeling
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Eur Urol 51:1244-50; discussion 1251. 2007..To study active surveillance as a management option for the important number of prostate cancer patients who would not have been diagnosed in the absence of screening...
Early detection of prostate cancer in 2007. Part 1: PSA and PSA kineticsFritz H Schroder
Department of Urology, Erasmus MC, Rotterdam, The Netherlands
Eur Urol 53:468-77. 2008..Screening for PCa has not yet been shown to lower PCa mortality. Still, opportunistic screening is wide spread in Europe and in most other parts of the world...
Screening for prostate cancer without digital rectal examination and transrectal ultrasound: results after four years in the European Randomized Study of Screening for Prostate Cancer (ERSPC), RotterdamClaartje Gosselaar
Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Prostate 66:625-31. 2006..0 ng/ml and/or abnormal DRE/TRUS (group-1) to solely a PSA cut-off of 3.0 ng/ml (group-2). We estimated the effect of omitting DRE/TRUS by comparing the results of a re-screening 4 years after initial screening to the original policy...
