Research Topics
Species | M A FrensSummaryAffiliation: Erasmus University Country: The Netherlands Publications
| Collaborators
|
Detail Information
Publications
Floccular complex spike response to transparent retinal slipM A Frens
Department of Physiology, Erasmus University Rotterdam, P O Box 1738, 3000 DR, Rotterdam, The Netherlands
Neuron 30:795-801. 2001..These results suggest that the climbing fiber code may be effectively related to the eye movement performance error, rather than to retinal slip...- Scleral search coils influence saccade dynamicsM A Frens
Department of Neuroscience, Erasmus University Rotterdam, The Netherlands
J Neurophysiol 88:692-8. 2002..Rather the coils appear to change the oculomotor command signals that drive the saccadic eye movements... - Increased noise level of purkinje cell activities minimizes impact of their modulation during sensorimotor controlF E Hoebeek
Department of Neuroscience, Erasmus MC, Dr Molenwaterplein 50, P O Box 1738, 3000 DR Rotterdam, The Netherlands
Neuron 45:953-65. 2005..This study demonstrates the importance of regularity of firing in Purkinje cells for neuronal information processing... - Expression of protein kinase C inhibitor blocks cerebellar long-term depression without affecting Purkinje cell excitability in alert miceJ Goossens
Department of Physiology, Neuroscience Institute, Erasmus University Rotterdam, 3000 DR Rotterdam, The Netherlands
J Neurosci 21:5813-23. 2001.... - The cervico-ocular reflex is increased in whiplash injury patientsW P A Kelders
Department of Neuroscience, Erasmus MC, 3000 DR Rotterdam, The Netherlands
J Neurotrauma 22:133-7. 2005..037, ANOVA). Hence, although larger numbers of patients should be measured, the COR gain appears to be a parameter that may permit an objective diagnosis of WAD... - Short-term adaptation of the cervico-ocular reflexD C Rijkaart
Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands
Exp Brain Res 156:124-8. 2004..Analysis showed a small but significant reduction in COR gain in the suppression conditions. This means that the cervico-ocular reflex can be modified after only 10 min of concurrent visual and cervical stimulation... - Visual-vestibular interaction during transparent optokinetic stimulation in the rabbitA L Mathoera
Department of Physiology, Erasmus University Rotterdam, The Netherlands
Exp Brain Res 125:87-96. 1999.... - Simple spike and complex spike activity of floccular Purkinje cells during the optokinetic reflex in mice lacking cerebellar long-term depressionH H L M Goossens
Department of Neuroscience, Erasmus MC, Dr Molewaterplein 50, 3000 DR Rotterdam, The Netherlands
Eur J Neurosci 19:687-97. 2004..The data thus strengthen the evidence that cerebellar LTD is implicated in rapid VOR learning but not in the development of normal default response patterns... - Visual depth processing in Williams-Beuren syndromeJ N van der Geest
Department of Neuroscience, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands
Exp Brain Res 166:200-9. 2005..We conclude that the problems that WBS patients have with tasks such as descending stairs are not due to an inability to judge distance... - Increased prevalences of left-handedness and left-eye sighting dominance in individuals with Williams-Beuren syndromeJ W Van Strien
Department of Psychology, Erasmus University Rotterdam, The Netherlands
J Clin Exp Neuropsychol 27:967-76. 2005..We suggest that the increased prevalence of left-handedness in WBS is a consequence of a slower maturation rate, which allows deviation from a predetermined laterality pattern... - Visual search deficits in Williams-Beuren syndromeI Montfoort
Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands
Neuropsychologia 45:931-8. 2007..This finding may be related to their motor deficits, an impaired processing of global visual information and/or deficits in working memory and could reflect impairments within the dorsal stream... - Saccade dysmetria in Williams-Beuren syndromeJ N van der Geest
Department of Neuroscience, Erasmus University Rotterdam, P O Box 1738, Erasmus MC, DR 3000, Rotterdam, The Netherlands
Neuropsychologia 42:569-76. 2004..We conclude that the observed impairments in saccadic control are likely to affect the proper processing of visuo-spatial information... - Copying strategies for patterns by children and adultsG C Lagers-van Haselen
Department of Physiology, Erasmus University Medical Faculty, Rotterdam, The Netherlands
Percept Mot Skills 91:603-15. 2000..The visual strategies of the children were highly comparable to those of adults. Memory was restricted to one block, while color and location seemed to be remembered together... 
Tragedy of conducting a clinical trial; generic alert system neededI Montfoort
Department of Neuroscience, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
J Clin Epidemiol 61:415-8. 2008..Several motives can be proposed that would have prevented this obliged halting from happening. Other studies also report impracticability of the planned number of whiplash injury patients...- Eye movements as a marker for cerebellar damage in paraneoplastic neurological syndromesP C A van Broekhoven
Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands
Parkinsonism Relat Disord 13:S296-300. 2007.... - Cerebellar contributions to the processing of saccadic errorsP C A van Broekhoven
Department of Neuroscience, Erasmus MC, Rotterdam 3000 CA, The Netherlands
Cerebellum 8:403-15. 2009..Future studies of these areas with, e.g., electrophysiological recordings, may reveal the nature of the error signals that drive the amplitude modification of saccadic eye movements... - The collicular code of saccade direction depends on the roll orientation of the head relative to gravityM A Frens
Neurology Department, University Hospital, Zurich, Switzerland
Exp Brain Res 120:283-90. 1998..We find that the mSC works in an oculocentric coordinate system that is biased in the direction of gravity. It is argued that the modification is a result of processes that occur downstream of or parallel to the mSC... - Visual-auditory interactions modulate saccade-related activity in monkey superior colliculusM A Frens
University of Nijmegen, Department of Medical Physics and Biophysics, The Netherlands
Brain Res Bull 46:211-24. 1998..These cells were always most active in the bimodal task when both stimuli were in spatial register, but activity decreased with increasing stimulus separation... - Inhibition of saccade initiation by preceding smooth pursuitR Kanai
Department of Neuroscience, EE1579, Erasmus MC, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands
Exp Brain Res 148:300-7. 2003..This is in contrast with the predictions of "Inhibition of Saccade Return" (ISR, Hooge and Frens 2000), which is restricted to a smaller confined area... - Recording eye movements with video-oculography and scleral search coils: a direct comparison of two methodsJ N van der Geest
Department of Physiology, Erasmus University Rotterdam, P O Box 1738, 3000 DR, Rotterdam, The Netherlands
J Neurosci Methods 114:185-95. 2002..A disadvantage of the video method is its low sample rate of 250 Hz. The relatively noisier estimate of all parameters of small saccades could be attributed to this low sampling frequency... - Inhibition of saccade return (ISR): spatio-temporal properties of saccade programmingI T Hooge
Department of Physiology, Erasmus University Rotterdam, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
Vision Res 40:3415-26. 2000..The radius of the area where ISR is found is about 4 degrees. The relation between ISR and 'Inhibition of Return' of spatial attention [Posner & Cohen, 1984] is discussed, as well as the neurophysiological basis of ISR... 
Compensatory increase of the cervico-ocular reflex with age in healthy humansW P A Kelders
Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands
J Physiol 553:311-7. 2003..A nearly constant phase lag between the COR and the VOR of about 25 deg existed at all stimulus frequencies...- Heading and path percepts from visual flow and eye pursuit signalsA V van den Berg
Department of Physiology, Helmholtz School for Autonomous Systems Research, Faculty of Medicine, Erasmus University Rotterdam, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
Vision Res 41:3467-86. 2001..It was suggested that bi-circular and bi-radial flow components contribute primarily to percepts of heading and path curvature, respectively... - Contribution of CYLN2 and GTF2IRD1 to neurological and cognitive symptoms in Williams SyndromeJ M van Hagen
Department of Clinical Genetics and Human Genetics, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Neurobiol Dis 26:112-24. 2007..We conclude that the motor and cognitive deficits in Williams Syndrome are caused by a variety of genes and that heterozygous deletion of CYLN2 is one of the major causes responsible for such dysfunctions... - Three-dimensional vestibular eye and head reflexes of the chameleon: characteristics of gain and phase and effects of eye position on orientation of ocular rotation axes during stimulation in yaw directionH Haker
Neurology Department, University Hospital of Zurich, 8091 Zurich, Switzerland
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 189:509-17. 2003..Therefore, vestibulo-ocular reflex responses in the chameleon follow a strategy, which optimally stabilizes the entire retinal images, a result previously found in non-human primates... - Chameleon eye position obeys Listing's lawP S Sandor
Neurology Department, University of Zurich, 8091 Zurich, Switzerland
Vision Res 41:2245-51. 2001..Since the anatomical arrangement of the orbit in chameleons is very different from that in primates, and binocular fused vision is virtually absent, we suggest that in the chameleon, LL mainly optimizes oculomotor control...