Research Topics
| D A M FestenSummaryAffiliation: Erasmus MC Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
Sleep-related breathing disorders in prepubertal children with Prader-Willi syndrome and effects of growth hormone treatmentD A M Festen
Dutch Growth Foundation, Westzeedijk 106, 3016 AH Rotterdam, The Netherlands
J Clin Endocrinol Metab 91:4911-5. 2006..GH treatment in PWS results in a remarkable growth response and an improvement of body composition and muscle strength. Data concerning effects on respiratory parameters, are however, limited...
Adiponectin levels in prepubertal children with Prader-Willi syndrome before and during growth hormone therapyD A M Festen
Dutch Growth Foundation, Westzeedijk 106, 3016 AH Rotterdam, The Netherlands
J Clin Endocrinol Metab 92:1549-54. 2007..Children with Prader-Willi syndrome (PWS) may have obesity and an abnormal body composition with a high body fat percentage, even if they have a normal body weight. Adiponectin has been inversely related to obesity and insulin resistance...
Psychomotor development in infants with Prader-Willi syndrome and associations with sleep-related breathing disordersDederieke A M Festen
Dutch Growth Foundation, 3016AH Rotterdam, The Netherlands
Pediatr Res 62:221-4. 2007....
Thyroid hormone levels in children with Prader-Willi syndrome before and during growth hormone treatmentD A M Festen
Dutch Growth Foundation, Rotterdam, The Netherlands
Clin Endocrinol (Oxf) 67:449-56. 2007..Several endocrine abnormalities have been described, including GH deficiency and hypogonadotrophic hypogonadism. Published data on thyroid hormone levels in PWS children are very limited...
Mental and motor development before and during growth hormone treatment in infants and toddlers with Prader-Willi syndromeD A M Festen
Dutch Growth Foundation, Rotterdam, The Netherlands
Clin Endocrinol (Oxf) 68:919-25. 2008..GH treatment improves growth velocity and body composition. Research on the effects of GH on psychomotor development in infants with PWS is limited...
Randomized controlled GH trial: effects on anthropometry, body composition and body proportions in a large group of children with Prader-Willi syndromeDederieke A M Festen
Dutch Growth and Research Foundation, Rotterdam, The Netherlands
Clin Endocrinol (Oxf) 69:443-51. 2008..Prader-Willi syndrome (PWS) children have impaired growth, and abnormal body composition. Previous 1-year controlled studies showed improvement of height and body composition during GH-treatment...
Cognition and behavior in pre-pubertal children with Prader-Willi syndrome and associations with sleep-related breathing disordersDederieke A M Festen
Dutch Growth Foundation, Rotterdam, The Netherlands
Am J Med Genet A 146:3018-25. 2008..In contrast, we could not confirm a positive association of neurobehavioral abnormalities with SRBD in PWS...
Scoliosis in Prader-Willi syndrome: prevalence, effects of age, gender, body mass index, lean body mass and genotypeR F A de Lind van Wijngaarden
Dutch Growth Research Foundation, Rotterdam, The Netherlands
Arch Dis Child 93:1012-6. 2008..The reported prevalence of scoliosis in children with Prader-Willi syndrome varies from 15% to 86%...
Bone mineral density and effects of growth hormone treatment in prepubertal children with Prader-Willi syndrome: a randomized controlled trialRoderick F A de Lind van Wijngaarden
Dutch Growth Research Foundation, Erasmus University Medical Center Sophia Children s Hospital, 3016 AH Rotterdam, The Netherlands
J Clin Endocrinol Metab 94:3763-71. 2009..Bone mineral density (BMD) is unknown in children with Prader-Willi syndrome (PWS), but is decreased in adults with PWS. In patients with GH deficiency, BMD increases during GH treatment...
Randomized controlled trial to investigate the effects of growth hormone treatment on scoliosis in children with Prader-Willi syndromeRoderick F A de Lind van Wijngaarden
Dutch Growth Research Foundation, Erasmus University Medical Center Sophia Children s Hospital, Rotterdam, The Netherlands
J Clin Endocrinol Metab 94:1274-80. 2009..Although reports about effects of GH treatment on scoliosis in children with PWS are limited, scoliosis is generally considered a contraindication for GH treatment...
High prevalence of central adrenal insufficiency in patients with Prader-Willi syndromeRoderick F A de Lind van Wijngaarden
Dutch Growth Research Foundation and Erasmus University Medical Center Sophia Children s Hospital, Westzeedijk 106, Rotterdam, The Netherlands
J Clin Endocrinol Metab 93:1649-54. 2008..The annual death rate of Prader-Willi syndrome (PWS) patients is very high (3%). Many of these deaths are sudden and unexplained...
Efficacy and safety of long-term continuous growth hormone treatment in children with Prader-Willi syndromeRoderick F A de Lind van Wijngaarden
Clinical Research Fellow, Dutch Growth Research Foundation, Erasmus University Medical Center Sophia Children s Hospital, Westzeedijk 106, 3016 AH Rotterdam, The Netherlands
J Clin Endocrinol Metab 94:4205-15. 2009..Children with Prader-Willi syndrome (PWS) have abnormal body composition and impaired growth. Short-term GH treatment has beneficial effects...
