Janine F Felix

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. doi request reprint Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
    Janine F Felix
    The Generation R Study Group, Department of Pediatrics, Department of Epidemiology
    Hum Mol Genet 25:389-403. 2016
  2. doi request reprint Health in children: a conceptual framework for use in healthy ageing research
    Janine F Felix
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands Electronic address
    Maturitas 77:47-51. 2014
  3. ncbi request reprint Chromosomal anomalies in the aetiology of oesophageal atresia and tracheo-oesophageal fistula
    Janine F Felix
    Department of Paediatric Surgery, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    Eur J Med Genet 50:163-75. 2007
  4. pmc Etiology of esophageal atresia and tracheoesophageal fistula: "mind the gap"
    Elisabeth M de Jong
    Department of Pediatric Surgery, Erasmus MC Sophia Children s Hospital, PO Box 2060, 3000 CB, Rotterdam, The Netherlands
    Curr Gastroenterol Rep 12:215-22. 2010
  5. doi request reprint Impact of maternal smoking during pregnancy on microvasculature in childhood. The Generation R Study
    Olta Gishti
    Department of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Early Hum Dev 91:607-11. 2015
  6. doi request reprint Early origins of ethnic disparities in cardiovascular risk factors
    Olta Gishti
    The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Rotterdam, The Netherlands Department of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands
    Prev Med 76:84-91. 2015
  7. pmc 5q11.2 deletion in a patient with tracheal agenesis
    Elisabeth M de Jong
    Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
    Eur J Hum Genet 18:1265-8. 2010
  8. doi request reprint Genetic and environmental factors in the etiology of esophageal atresia and/or tracheoesophageal fistula: an overview of the current concepts
    Janine F Felix
    Department of Pediatric Surgery, Erasmus MC Sophia Children s Hospital, 3000 CB Rotterdam, The Netherlands
    Birth Defects Res A Clin Mol Teratol 85:747-54. 2009
  9. doi request reprint Non-VACTERL-type anomalies are frequent in patients with esophageal atresia/tracheo-esophageal fistula and full or partial VACTERL association
    Elisabeth M de Jong
    Department of Pediatric Surgery, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    Birth Defects Res A Clin Mol Teratol 82:92-7. 2008
  10. doi request reprint Effects of choline on health across the life course: a systematic review
    Elisabeth T M Leermakers
    E T M Leermakers, E M Moreira, J C Kiefte de Jong, S K L Darweesh, T Visser, T Voortman, P K Bautista, J F Felix, and O H Franco are with the Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands R Chowdhury and D Gorman are with the Department of Public Health and Primary Care, Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, United Kingdom W M Bramer is with the Medical Library, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Nutr Rev 73:500-22. 2015

Collaborators

Detail Information

Publications25

  1. doi request reprint Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
    Janine F Felix
    The Generation R Study Group, Department of Pediatrics, Department of Epidemiology
    Hum Mol Genet 25:389-403. 2016
    ..This study highlights the shared genetic background between childhood and adult body mass index and adds three novel loci. These loci likely represent age-related differences in strength of the associations with body mass index. ..
  2. doi request reprint Health in children: a conceptual framework for use in healthy ageing research
    Janine F Felix
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands Electronic address
    Maturitas 77:47-51. 2014
    ..The aim of this paper was to develop a conceptual framework for child health, which can be used as a starting point for healthy ageing research from a life course perspective...
  3. ncbi request reprint Chromosomal anomalies in the aetiology of oesophageal atresia and tracheo-oesophageal fistula
    Janine F Felix
    Department of Paediatric Surgery, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    Eur J Med Genet 50:163-75. 2007
    ..This paper reviews the chromosomal abnormalities reported in cases of OA/TOF and serves as a starting point to identify chromosomal regions harbouring genes involved in the aetiology of OA/TOF...
  4. pmc Etiology of esophageal atresia and tracheoesophageal fistula: "mind the gap"
    Elisabeth M de Jong
    Department of Pediatric Surgery, Erasmus MC Sophia Children s Hospital, PO Box 2060, 3000 CB, Rotterdam, The Netherlands
    Curr Gastroenterol Rep 12:215-22. 2010
    ..Recent advances in genotyping technology and in knowledge of human genetic variation will improve clinical counseling on etiologic factors. This review provides a clinical summary of environmental and genetic factors involved in EA/TEF...
  5. doi request reprint Impact of maternal smoking during pregnancy on microvasculature in childhood. The Generation R Study
    Olta Gishti
    Department of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Early Hum Dev 91:607-11. 2015
    ..Fetal exposure to maternal smoking is associated with an adverse cardiovascular risk profile in later life. Early microvasculature adaptations might be part of the underlying mechanisms for these associations...
  6. doi request reprint Early origins of ethnic disparities in cardiovascular risk factors
    Olta Gishti
    The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Rotterdam, The Netherlands Department of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands
    Prev Med 76:84-91. 2015
    ..Not much is known about the ethnic differences in cardiovascular risk factors during childhood in European countries. We examined the ethnic differences in childhood cardiovascular risk factors in the Netherlands...
  7. pmc 5q11.2 deletion in a patient with tracheal agenesis
    Elisabeth M de Jong
    Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
    Eur J Hum Genet 18:1265-8. 2010
    ..No common deletions or duplications are found in our cohort, suggesting that TA is a genetically heterogeneous disorder...
  8. doi request reprint Genetic and environmental factors in the etiology of esophageal atresia and/or tracheoesophageal fistula: an overview of the current concepts
    Janine F Felix
    Department of Pediatric Surgery, Erasmus MC Sophia Children s Hospital, 3000 CB Rotterdam, The Netherlands
    Birth Defects Res A Clin Mol Teratol 85:747-54. 2009
    ..Environmental factors may also carry a risk, but the mechanisms are yet to be elucidated. This review gives an overview of the current state of knowledge about both genetic and environmental risk factors in the etiology of EA/TEF...
  9. doi request reprint Non-VACTERL-type anomalies are frequent in patients with esophageal atresia/tracheo-esophageal fistula and full or partial VACTERL association
    Elisabeth M de Jong
    Department of Pediatric Surgery, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    Birth Defects Res A Clin Mol Teratol 82:92-7. 2008
    ..The full phenotype of patients with EA/TEF and other anomalies of the VACTERL spectrum of defects association is not well described in the literature...
  10. doi request reprint Effects of choline on health across the life course: a systematic review
    Elisabeth T M Leermakers
    E T M Leermakers, E M Moreira, J C Kiefte de Jong, S K L Darweesh, T Visser, T Voortman, P K Bautista, J F Felix, and O H Franco are with the Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands R Chowdhury and D Gorman are with the Department of Public Health and Primary Care, Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, United Kingdom W M Bramer is with the Medical Library, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Nutr Rev 73:500-22. 2015
    ..There has been concern, however, that it may influence blood lipid levels because it is an essential component of very-low-density lipoproteins...
  11. doi request reprint Body mass index, gestational weight gain and fatty acid concentrations during pregnancy: the Generation R Study
    Aleksandra Jelena Vidakovic
    The Generation R Study Group Na29 15, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 30:1175-85. 2015
    ..Our results suggest that obesity and excessive weight gain during pregnancy are associated with an adverse fatty acids profile. Further studies are needed to assess causality and direction of the observed associations. ..
  12. doi request reprint Sugar-containing beverage intake at the age of 1 year and cardiometabolic health at the age of 6 years: the Generation R Study
    Elisabeth T M Leermakers
    Generation R Study Group, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Int J Behav Nutr Phys Act 12:114. 2015
    ..We studied the associations of SCB intake at the age of 1 year with cardiometabolic health at age 6 years...
  13. doi request reprint Ethnic disparities in maternal obesity and weight gain during pregnancy. The Generation R Study
    Sunayna Bahadoer
    The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, The Netherlands Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Eur J Obstet Gynecol Reprod Biol 193:51-60. 2015
    ..To examine ethnic disparities in maternal prepregnancy obesity and gestational weight gain, and to examine to which extent these differences can be explained by socio-demographic, lifestyle and pregnancy related characteristics...
  14. doi request reprint Influence of maternal angiogenic factors during pregnancy on microvascular structure in school-age children
    Olta Gishti
    From the Generation R Study Group O G, V W V J, J F F, R G, and Departments of Pediatrics O G, V W V J, I R, R G, Epidemiology O G, V W V J, J F F, A H, R G, Ophthalmology M K I, Obstetrics and Gynecology E A P S, and Neonatology I R, Erasmus MC, University Medical Center, Rotterdam, the Netherlands Singapore Eye Research Institute and Duke NUS Graduate Medical School, National University of Singapore, Singapore, Singapore M K I and Memory Aging and Cognition Centre MACC, National University of Health System, Singapore, Singapore M K I
    Hypertension 65:722-8. 2015
    ..Further studies are needed to confirm these findings and to explore the underlying mechanisms and long-term cardiovascular consequences. ..
  15. doi request reprint Retinal microvasculature and cardiovascular health in childhood
    Olta Gishti
    The Generation R Study Group, Department of Pediatrics, Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, Netherlands
    Pediatrics 135:678-85. 2015
    ..Alterations in retinal microvasculature are associated with increased risk of cardiovascular disease. We examined the associations of retinal vessel caliber with cardiovascular markers in school-age children...
  16. doi request reprint Ethnic disparities in general and abdominal adiposity at school age: a multiethnic population-based cohort study in the Netherlands
    Olta Gishti
    Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands
    Ann Nutr Metab 64:208-17. 2014
    ..We examined ethnic differences in general and abdominal fat distribution in school-age children and the influence of parental prepregnancy, pregnancy, and childhood factors on these differences...
  17. ncbi request reprint Esophageal atresia and tracheoesophageal fistula in children of women exposed to diethylstilbestrol in utero
    Janine F Felix
    Department of Pediatric Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Am J Obstet Gynecol 197:38.e1-5. 2007
    ..This study was undertaken to study the possible risk to mothers exposed in utero to diethylstilbestrol for offspring with esophageal atresia/tracheoesophageal fistula...
  18. doi request reprint Childhood cardiometabolic outcomes of maternal obesity during pregnancy: the Generation R Study
    Romy Gaillard
    The Generation R Study Group Na29 15, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Hypertension 63:683-91. 2014
    ..These findings suggest that maternal prepregnancy BMI may influence the cardiometabolic health of offspring through direct intrauterine mechanisms. ..
  19. doi request reprint The Influence of Known Genetic Variants on Subclinical Cardiovascular Outcomes in Childhood: Generation R Study
    Rani V G Punwasi
    From the The Generation R Study Group R V G P, C M, A H, V W V J, J F F, Department of Epidemiology R V G P, C M, A H, V W V J, J F F, and Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands R V G P, C M, V W V J, J F F
    Circ Cardiovasc Genet 8:596-602. 2015
    ..Genome-wide association studies have identified single-nucleotide polymorphisms (SNPs) for subclinical cardiovascular outcomes in adults. We examined the influence of these variants on the same outcomes in childhood...
  20. doi request reprint Maternal fish consumption, fatty acid levels and angiogenic factors: The Generation R Study
    Paula K Bautista Niño
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Placenta 36:1178-84. 2015
    ..We investigated the associations of maternal fish consumption and fatty acids levels with angiogenic factors during pregnancy, and in cord blood in a large population-based prospective cohort...
  21. doi request reprint Effects of protein intake on blood pressure, insulin sensitivity and blood lipids in children: a systematic review
    Trudy Voortman
    Department of Epidemiology, Erasmus MC, University Medical Center, PO Box 2040, 3000CA, Rotterdam, The Netherlands
    Br J Nutr 113:383-402. 2015
    ..Future studies could be improved by adequately adjusting for key confounders such as energy intake and obesity. ..
  22. doi request reprint Childhood consequences of maternal obesity and excessive weight gain during pregnancy
    Romy Gaillard
    The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands Department of Pediatrics, Erasmus Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Acta Obstet Gynecol Scand 93:1085-9. 2014
    ..Also, the potential for prevention of common diseases in future generations by reducing maternal obesity and excessive weight gain during pregnancy needs to be explored. ..
  23. doi request reprint Environmental factors in the etiology of esophageal atresia and congenital diaphragmatic hernia: results of a case-control study
    Janine F Felix
    Department of Pediatric Surgery, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    Birth Defects Res A Clin Mol Teratol 82:98-105. 2008
    ..Their etiologies are mostly unknown and are thought to be multifactorial. No specific environmental factors have consistently been described as risk factors...
  24. ncbi request reprint Agenesis of the trachea: phenotypic expression of a rare cause of fatal neonatal respiratory insufficiency in six patients
    Janine F Felix
    Department of Pediatric Surgery, Erasmus MC Sophia Children s Hospital, Rotterdam, The Netherlands
    Int J Pediatr Otorhinolaryngol 70:365-70. 2006
    ..Associated anomalies were found in five cases. The classification of tracheal agenesis, associated anomalies and potential therapeutic options are discussed...
  25. doi request reprint Prevalence of Pulmonary Hypertension in the General Population: The Rotterdam Study
    Eduardo M Moreira
    Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands School of Medicine, Pontifical Catholic University of Parana, Curitiba, Brazil
    PLoS ONE 10:e0130072. 2015
    ..We aimed to describe the distribution of echocardiographically-assessed pulmonary artery systolic pressure (ePASP) in the general population, to estimate the prevalence of pulmonary hypertension, and to identify associated factors...