I Esmé Dijke

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. doi request reprint Inadequate immune regulatory function of CD4+CD25bright+FoxP3+ T cells in heart transplant patients who experience acute cellular rejection
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Transplantation 87:1191-200. 2009
  2. ncbi request reprint Donor-specific cytotoxic hyporesponsiveness associated with high interleukin-10 messenger RNA expression in cardiac allograft patients
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Heart Lung Transplant 25:955-64. 2006
  3. doi request reprint Donor-specific immune regulation by CD8 lymphocytes expanded from rejecting human cardiac allografts
    I E Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Am J Transplant 9:397-403. 2009
  4. doi request reprint Regulatory T cells after organ transplantation: where does their action take place?
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Hum Immunol 69:389-98. 2008
  5. doi request reprint The control of anti-donor immune responses by regulatory T cells in organ transplant patients
    I E Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Transplant Proc 40:1249-52. 2008
  6. ncbi request reprint FOXP3 mRNA expression analysis in the peripheral blood and allograft of heart transplant patients
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Transpl Immunol 18:250-4. 2008
  7. ncbi request reprint Intragraft FOXP3 mRNA expression reflects antidonor immune reactivity in cardiac allograft patients
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Transplantation 83:1477-84. 2007
  8. ncbi request reprint FoxP3+ T cells can be expanded from rejecting cardiac allografts
    E Dijke
    Department of Internal Medicine Transplantation, Erasmus Medical Center, Rotterdam, Netherlands
    Transplant Proc 38:3233-5. 2006
  9. ncbi request reprint Interleukin-21: an interleukin-2 dependent player in rejection processes
    Carla C Baan
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Transplantation 83:1485-92. 2007
  10. doi request reprint Regulatory T cells in alloreactivity after clinical heart transplantation
    Carla C Baan
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Curr Opin Organ Transplant 14:577-82. 2009

Detail Information

Publications11

  1. doi request reprint Inadequate immune regulatory function of CD4+CD25bright+FoxP3+ T cells in heart transplant patients who experience acute cellular rejection
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Transplantation 87:1191-200. 2009
    ..CD4CD25FoxP3 regulatory T cells are suppressors of antigen-activated immune reactivity. Here, we assessed the clinically relevant role of these cells in the control of immune responses directed to a transplanted heart...
  2. ncbi request reprint Donor-specific cytotoxic hyporesponsiveness associated with high interleukin-10 messenger RNA expression in cardiac allograft patients
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Heart Lung Transplant 25:955-64. 2006
    ..In this study, we determined whether cardiac allograft recipients show donor-specific hyporesponsiveness and studied the underlying mechanisms...
  3. doi request reprint Donor-specific immune regulation by CD8 lymphocytes expanded from rejecting human cardiac allografts
    I E Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Am J Transplant 9:397-403. 2009
    ..We suggest that during acute cellular rejection, GLs may not only consist of graft-destructing effector T cells, but also of cells of the CD8(+) type with the potential to specifically inhibit antidonor immune reactivity...
  4. doi request reprint Regulatory T cells after organ transplantation: where does their action take place?
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Hum Immunol 69:389-98. 2008
    ..In addition, we discuss the importance of the appropriate localization for the control of anti-donor immune reactivity...
  5. doi request reprint The control of anti-donor immune responses by regulatory T cells in organ transplant patients
    I E Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Transplant Proc 40:1249-52. 2008
    ..Subsequently, monitoring regulatory T cells may help us to identify patients in whom the anti-donor reactivity is actively suppressed...
  6. ncbi request reprint FOXP3 mRNA expression analysis in the peripheral blood and allograft of heart transplant patients
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Transpl Immunol 18:250-4. 2008
    ....
  7. ncbi request reprint Intragraft FOXP3 mRNA expression reflects antidonor immune reactivity in cardiac allograft patients
    I Esmé Dijke
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Transplantation 83:1477-84. 2007
    ..Therefore, we analyzed the gene expression profiles of regulatory and effector T-cell markers during immunological quiescence and acute rejection...
  8. ncbi request reprint FoxP3+ T cells can be expanded from rejecting cardiac allografts
    E Dijke
    Department of Internal Medicine Transplantation, Erasmus Medical Center, Rotterdam, Netherlands
    Transplant Proc 38:3233-5. 2006
    ..Of these GILs, 10.6% (median; range, 1.6%-17.1%) stained positive for FoxP3. Thus Foxp3+ T cells can be grown from EMBs, providing the tools to functionally characterize these cells in depth in forthcoming studies...
  9. ncbi request reprint Interleukin-21: an interleukin-2 dependent player in rejection processes
    Carla C Baan
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Transplantation 83:1485-92. 2007
    ..Interleukin (IL)-21 is the most recently described cytokine that signals via the common cytokine receptor (gammac), is produced by activated CD4+ T-cells, and regulates expansion and effector function of CD8+ T-cells...
  10. doi request reprint Regulatory T cells in alloreactivity after clinical heart transplantation
    Carla C Baan
    Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Curr Opin Organ Transplant 14:577-82. 2009
    ..This review focuses on the function of regulatory T cells in the peripheral blood and the transplanted organ of patients after heart transplantation during immunological quiescence and rejection...
  11. doi request reprint Myelin ingestion alters macrophage antigen-presenting function in vitro and in vivo
    Marloes Van Zwam
    Department of Immunology, University Medical Center, P O Box 2040, Rotterdam, Zuid Holland 3000 CA, The Netherlands
    J Leukoc Biol 90:123-32. 2011
    ..These data show that myelin uptake results in the induction of a population of macrophages that retains antigen-presenting capacity and limits autoimmune-mediated disease...