Marieke C J Dekker

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi Parkinson's disease: piecing together a genetic jigsaw
    M C J Dekker
    Genetic Epidemiologic Unit, Erasmus Medical Centre, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Brain 126:1722-33. 2003
  2. ncbi Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism
    Marieke C J Dekker
    Department of Epidemiology and Biostatistics, Erasmus MC, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Neurosci Lett 348:117-9. 2003
  3. ncbi Evidence for novel loci for late-onset Parkinson's disease in a genetic isolate from the Netherlands
    Aida M Bertoli-Avella
    Genetic Epidemiologic Unit, Department of Clinical Genetics and Department of Epidemiology and Biostatistics, Erasmus MC Rotterdam, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
    Hum Genet 119:51-60. 2006
  4. ncbi A deletion in DJ-1 and the risk of dementia--a population-based survey
    Alejandro Arias Vasquez
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Neurosci Lett 372:196-9. 2004
  5. ncbi Loss of nuclear activity of the FBXO7 protein in patients with parkinsonian-pyramidal syndrome (PARK15)
    Tianna Zhao
    Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
    PLoS ONE 6:e16983. 2011
  6. ncbi Prospects of genetic epidemiology in the 21st century
    Marieke C J Dekker
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Eur J Epidemiol 18:607-16. 2003
  7. ncbi Phenotypic subtypes in attention deficit hyperactivity disorder in an isolated population
    Esther A Croes
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus Medical Centre, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Eur J Epidemiol 20:789-94. 2005
  8. ncbi Attention-deficit/hyperactivity disorder (ADHD): parents' judgment about school, teachers' judgment about home
    Pieter F A de Nijs
    Outpatients Department of Child and Adolescent Psychiatry, Erasmus MC Sophia Children s Hospital, 3000 CB Rotterdam, The Netherlands
    Eur Child Adolesc Psychiatry 13:315-20. 2004
  9. ncbi Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
    Vincenzo Bonifati
    Genetic Epidemiologic Unit, Department of Clinical Genetics, Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, Post Office Box 1738, 3000 DR Rotterdam, Netherlands
    Science 299:256-9. 2003
  10. ncbi Brachydactyly and short stature in a kindred with early-onset parkinsonism
    Marieke C J Dekker
    Am J Med Genet A 130:102-4. 2004

Detail Information

Publications10

  1. ncbi Parkinson's disease: piecing together a genetic jigsaw
    M C J Dekker
    Genetic Epidemiologic Unit, Erasmus Medical Centre, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Brain 126:1722-33. 2003
    ..We review advances in the genetics of Parkinson's disease, focusing on the monogenic forms and their clinical and population-genetic consequences...
  2. ncbi Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism
    Marieke C J Dekker
    Department of Epidemiology and Biostatistics, Erasmus MC, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Neurosci Lett 348:117-9. 2003
    ..009, P=0.006, respectively). Our data are hampered by small numbers, yet suggest that the C282Y mutation increases the risk of PD and non-PD PS. The rarity of this genotype requires a large series of patients to prove our hypothesis...
  3. ncbi Evidence for novel loci for late-onset Parkinson's disease in a genetic isolate from the Netherlands
    Aida M Bertoli-Avella
    Genetic Epidemiologic Unit, Department of Clinical Genetics and Department of Epidemiology and Biostatistics, Erasmus MC Rotterdam, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
    Hum Genet 119:51-60. 2006
    ..7-6.1, P < 0.001). Moreover, a common haplotype with excess of sharing among late-onset PD cases was observed on both regions. Our results suggest the existence of two loci influencing PD susceptibility on chromosome 9q and 14q...
  4. ncbi A deletion in DJ-1 and the risk of dementia--a population-based survey
    Alejandro Arias Vasquez
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Neurosci Lett 372:196-9. 2004
    ..All subjects were heterozygous for the deletion and related to a common ancestor within eight generations. Our results suggest it is unlikely that haploinsufficiency in the DJ-1 gene imparts an increased risk for dementia...
  5. ncbi Loss of nuclear activity of the FBXO7 protein in patients with parkinsonian-pyramidal syndrome (PARK15)
    Tianna Zhao
    Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
    PLoS ONE 6:e16983. 2011
    ..The activity of FBXO7 in the nucleus appears therefore crucial for the maintenance of brain neurons and the pathogenesis of PARK15...
  6. ncbi Prospects of genetic epidemiology in the 21st century
    Marieke C J Dekker
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Eur J Epidemiol 18:607-16. 2003
    ....
  7. ncbi Phenotypic subtypes in attention deficit hyperactivity disorder in an isolated population
    Esther A Croes
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus Medical Centre, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Eur J Epidemiol 20:789-94. 2005
    ..01). Our data suggests that using two informants in diagnosing ADHD helps identify a phenotype with a strong genetic component. The inattentive phenotype showed strong familial clustering and evidence of a recessive origin...
  8. ncbi Attention-deficit/hyperactivity disorder (ADHD): parents' judgment about school, teachers' judgment about home
    Pieter F A de Nijs
    Outpatients Department of Child and Adolescent Psychiatry, Erasmus MC Sophia Children s Hospital, 3000 CB Rotterdam, The Netherlands
    Eur Child Adolesc Psychiatry 13:315-20. 2004
    ..The aim of this study was to separate sources of observer and situational variance in reporting attention-deficit/hyperactivity disorder (ADHD) symptomatology...
  9. ncbi Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
    Vincenzo Bonifati
    Genetic Epidemiologic Unit, Department of Clinical Genetics, Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, Post Office Box 1738, 3000 DR Rotterdam, Netherlands
    Science 299:256-9. 2003
    ..Elucidating the physiological role of DJ-1 protein may promote understanding of the mechanisms of brain neuronal maintenance and pathogenesis of Parkinson's disease...
  10. ncbi Brachydactyly and short stature in a kindred with early-onset parkinsonism
    Marieke C J Dekker
    Am J Med Genet A 130:102-4. 2004
    ..Since the bone length reduction was more pronounced in the homozygous parkinsonism patients than in their heterozygous relatives, however, the PARK7 region may contain a modifier gene for growth...