Research Topics
Genomes and GenesSpecies | Jaap W DeckersSummaryAffiliation: Erasmus MC Country: The Netherlands Publications
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Publications
[Trends in prevalence of cardiovascular risk factors and their treatment in coronary heart disease: the Euroaspire-project]Jaap W Deckers
Erasmus MC, afd Cardiologie, Rotterdam, The Netherlands
Ned Tijdschr Geneeskd 154:A1229. 2010..To determine the prevalence of cardiovascular risk factors and their treatment in Dutch patients with coronary heart disease (the 'Euroaspire'-project) and to compare these data with those from 4 and 10 years previously...
The new European Society of Cardiology guidelines on myocardial revascularisation: an appraisalSjoerd T Nauta
Thoraxcentre, Room Bd 420, Dr Molewaterplein 40, 3015 RD Rotterdam, The Netherlands
Heart 98:11-4. 2012..There may be a role for procedure oriented guidelines but, in that case, the items at issue should remain confined to matters directly related to technical aspects of the procedure...
Treatment benefit by perindopril in patients with stable coronary artery disease at different levels of riskJaap W Deckers
Department of Cardiology, Thoraxcenter, Erasmus University Medical Center Rotterdam, The Netherlands
Eur Heart J 27:796-801. 2006..We developed a cardiovascular risk model based on the EUROPA study population and investigated whether benefit of long-term administration of the angiotensin-converting enzyme (ACE)-inhibitor perindopril was modified by risk level...
Coronary calcification and the risk of heart failure in the elderly: the Rotterdam StudyMaarten J G Leening
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
JACC Cardiovasc Imaging 5:874-80. 2012..The purpose of this study was to determine the association of coronary artery calcification (CAC) with incident heart failure in the elderly and examine its independence of overt coronary heart disease (CHD)...
Sex-related trends in mortality in hospitalized men and women after myocardial infarction between 1985 and 2008: equal benefit for women and menSjoerd T Nauta
Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
Circulation 126:2184-9. 2012..We aimed to study sex-related differences in temporal trends in short- and long-term mortality from 1985 to 2008 in patients hospitalized for acute myocardial infarction...
Mortality in patients with hypertension on angiotensin-I converting enzyme (ACE)-inhibitor treatment is influenced by the ACE insertion/deletion polymorphismGysèle S Bleumink
Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
Pharmacogenet Genomics 15:75-81. 2005..We studied the possible interaction between ACE-inhibitor therapy in patients with hypertension and the ACE I/D polymorphism in incident heart failure and death...
Distribution of echocardiographic parameters and their associations with cardiovascular risk factors in the Rotterdam StudyIsabella Kardys
Department of Epidemiology, Erasmus Medical Center, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
Eur J Epidemiol 25:481-90. 2010..In conclusion, ventricular systolic and diastolic dysfunction is present in asymptomatic individuals. Selected established cardiovascular risk factors are associated with structural, systolic and diastolic parameters...
Prognostic markers in young patients with premature coronary heart diseaseJanine E van Loon
Department of Haematology, Erasmus University Medical Center, Rotterdam, The Netherlands
Atherosclerosis 224:213-7. 2012..To evaluate the survival and prognostic implications of cardiovascular, inflammatory and prothrombotic risk factors in young patients with premature coronary heart disease (CHD)...
Incidence of recognized and unrecognized myocardial infarction in men and women aged 55 and older: the Rotterdam StudyAnneke De Torbal
Department of Epidemiology and Biostatistics, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands
Eur Heart J 27:729-36. 2006....
Prolonged QTc interval and risk of sudden cardiac death in a population of older adultsSabine M J M Straus
Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
J Am Coll Cardiol 47:362-7. 2006..0 (95% confidence interval 2.1 to 31.3). CONCLUSIONS: Abnormal QTc prolongation on the electrocardiogram should be viewed as an independent risk factor for sudden cardiac death...
Seven-year safety and efficacy of the unrestricted use of drug-eluting stents in saphenous vein bypass graftsSjoerd T Nauta
Thoraxcenter, Erasmus Medical Center, Ba 559 Dr Molewaterplein 40, 3015GD Rotterdam, The Netherlands
Catheter Cardiovasc Interv 79:912-8. 2012..The aim was to investigate the 7-year clinical outcomes of patients treated with either drug-eluting stents (DES) or bare-metal stents (BMS) for saphenous vein graft disease (SVG)...
Variation in the von Willebrand factor gene is associated with von Willebrand factor levels and with the risk for cardiovascular diseaseMarianne C van Schie
Department of Hematology, Erasmus University Medical Centre, Rotterdam, The Netherlands
Blood 117:1393-9. 2011..44; 95% confidence interval [CI], 1.12-1.86 per minor allele). We confirmed the association between rs1063857 and CVD risk. Our data show that common variants in the VWF gene are associated with VWF levels and with the risk for CVD...
The cardioprotective effects of the angiotensin-converting enzyme inhibitor perindopril in patients with stable coronary artery disease are not modified by mild to moderate renal insufficiency: insights from the EUROPA trialJasper J Brugts
Department of Cardiology, Thoraxcenter Erasmus Medical Center, Rotterdam, The Netherlands
J Am Coll Cardiol 50:2148-55. 2007..This study sought to examine whether the cardioprotective effects of angiotensin-converting enzyme (ACE) inhibitor therapy by perindopril are modified by renal function in patients with stable coronary artery disease...
C-reactive protein and risk of heart failure. The Rotterdam StudyIsabella Kardys
Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
Am Heart J 152:514-20. 2006..CONCLUSIONS: C-reactive protein is strongly and independently associated with occurrence of heart failure in men. In women, the association is weaker and does not persist after accounting for established cardiovascular risk factors...
Unrecognised myocardial infarction and long-term risk of heart failure in the elderly: the Rotterdam StudyMaarten J G Leening
Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
Heart 96:1458-62. 2010..To examine the association between unrecognised myocardial infarction (MI) as detected by electrocardiography and the long-term risk of heart failure...
Smoking behaviour in European patients with established coronary heart diseaseWilma Scholte op Reimer
Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
Eur Heart J 27:35-41. 2006..Thus, still there is a need for the development of effective smoking cessation programmes...
Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam StudyGysèle S Bleumink
Department of Epidemiology and Biostatistics, Erasmus Medical Centre, PO Box 1738, 3000, Rotterdam, The Netherlands
Eur Heart J 25:1614-9. 2004..To determine the prevalence, incidence rate, lifetime risk and prognosis of heart failure...
Genetic polymorphisms and heart failureGysèle S Bleumink
Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
Genet Med 6:465-74. 2004....
Echocardiographic parameters and all-cause mortality: the Rotterdam StudyIsabella Kardys
Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
Int J Cardiol 133:198-204. 2009..However, data on the predictive value of echocardiographic characteristics in the general population remain relatively scarce...
Methods of data collection and definitions of cardiac outcomes in the Rotterdam StudyMaarten J G Leening
Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Eur J Epidemiol 27:173-85. 2012..In all, detailed description of cardiac outcome definitions enhances the possibility to make comparisons with other studies in the field of cardiovascular research and may increase the strength of collaborations...
Effect of anemia on short- and long-term outcome in patients hospitalized for acute coronary syndromesJohn O Younge
Erasmus Medical Center, Thoraxcenter, Department of Cardiology, Rotterdam, The Netherlands
Am J Cardiol 109:506-10. 2012..25 to 0.51). In conclusion, presence and severity of anemia is an important predictor of higher in-hospital and long-term mortality after ACS. In addition, since the 1980s in-hospital outcome of patients with ACS and anemia has improved...
Blood pressure is insufficiently controlled in European patients with established coronary heart diseaseEric Boersma
Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
J Hypertens 21:1831-40. 2003..Adequate blood pressure control is therefore of utmost importance. We report on two successive European surveys that evaluated whether the goals given in recommendations on secondary prevention are achieved...
Effect of genetic variations in syntaxin-binding protein-5 and syntaxin-2 on von Willebrand factor concentration and cardiovascular riskJanine E van Loon
Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands
Circ Cardiovasc Genet 3:507-12. 2010..Furthermore, in our study, genetic variability in STX2 is associated with the risk of arterial thrombosis. However, at this point, the underlying mechanism remains unclear...
Short- and long-term mortality after myocardial infarction in patients with and without diabetes: changes from 1985 to 2008Sjoerd T Nauta
Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
Diabetes Care 35:2043-7. 2012..To study temporal trends in short- and long-term outcome after myocardial infarction (MI) according to diabetes status...
Long-term effect of perindopril on coronary atherosclerosis progression (from the perindopril's prospective effect on coronary atherosclerosis by angiography and intravascular ultrasound evaluation [PERSPECTIVE] study)Gaston A Rodriguez Granillo
Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
Am J Cardiol 100:159-63. 2007....
N-terminal pro-brain natriuretic peptide testing in the emergency department: beneficial effects on hospitalization, costs, and outcomeJoost H W Rutten
Department of Internal Medicine, Erasmus Medical College University Medical Center Rotterdam, Rotterdam, The Netherlands
Am Heart J 156:71-7. 2008..Assessment of this biomarker in patients with acute dyspnea presenting to the emergency department (ED) may aid diagnostic decision-making, resulting in improved patient care and reduced costs...
Contribution of nursing to risk factor management as perceived by patients with established coronary heart diseaseWilma J M Scholte op Reimer
Department of Cardiology Clinical Epidemiology, Erasmus Medical Center Rotterdam, Dijkzigt Hospital, Room H556, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
Eur J Cardiovasc Nurs 1:87-94. 2002..Guidelines stress the importance of risk factor management in patients with coronary heart disease (CHD)...
Changes in clinical profile, treatment, and mortality in patients hospitalised for acute myocardial infarction between 1985 and 2008Sjoerd T Nauta
Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
PLoS ONE 6:e26917. 2011....
Feelings of being disabled as a risk factor for mortality up to 8 years after acute myocardial infarctionMaureen J van der Vlugt
Thoraxcentre, Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
J Psychosom Res 59:247-53. 2005..This finding adds to the existing knowledge that psychosocial variables influence morbidity and mortality in cardiac patients...
Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study)Gysèle S Bleumink
Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
Am J Cardiol 94:384-6. 2004....
Microsimulation for clinical decision-making in individual patients with established coronary artery disease- a conceptLinda Battes
Clinical Epidemiology Unit, Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
Circ J 77:717-24. 2013..We aim to further familiarize clinicians with the concept of microsimulation and to inform them about the modeling process...
Hypofibrinolysis is a risk factor for arterial thrombosis at young ageAna H C Guimarães
Department of Haematology, Erasmus University Medical Centre, Rotterdam, The Netherlands
Br J Haematol 145:115-20. 2009..This points to an important contribution of hypofibrinolysis to the burden of arterial thrombosis...
The association of Rose questionnaire angina pectoris and coronary calcification in a general population: the Rotterdam Coronary Calcification StudyHok-Hay S Oei
Department of Epidemiology and Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands
Ann Epidemiol 14:431-6. 2004..CONCLUSIONS: Rose questionnaire angina pectoris is strongly associated with the amount of coronary calcification. Rose questionnaire angina pectoris corresponds better with the amount of coronary calcification in men than in women...
Early angioplasty in acute coronary syndromes without persistent ST-segment elevation improves outcome but increases the need for six-month repeat revascularization: an analysis of the PURSUIT Trial. Platelet glycoprotein IIB/IIIA in Unstable angina: ReceEelko Ronner
University Hospital Rotterdam, Rotterdam, The Netherlands
J Am Coll Cardiol 39:1924-9. 2002....
Statin prescription in men and women at cardiovascular risk: to whom and when?Jasper J Brugts
Department of Cardiology, Erasmus MC Thoraxcenter, Rotterdam, The Netherlands
Curr Opin Cardiol 25:484-9. 2010..To review the recent evidence of the effectiveness of statin therapy in the primary prevention of cardiovascular disease in men and women without established cardiovascular disease (CVD)...
Prognostic importance of new small Q waves following non-ST-elevation acute coronary syndromesJohn H Alexander
Duke Clinical Research Institute, Durham, North Carolina 27710, USA
Am J Med 115:613-9. 2003..To investigate the prognostic importance of new small Q waves following an acute coronary syndrome...
Insight into ACE inhibition in the prevention of cardiac events in stable coronary artery disease: the EUROPA trialRoberto Ferrari
Chair of Cardiology, University of Ferrara, Arcispedale S Anna, Corso Giovecca 203, 44100, Ferrara, Italy
Expert Rev Cardiovasc Ther 5:1037-46. 2007..Data on the pathophysiological mechanisms underlying CAD indicate direct vascular protection with perindopril. This helps explain why perindopril is beneficial in preventing cardiac events in stable CAD patients...
Efficacy of perindopril in reducing risk of cardiac events in patients with revascularized coronary artery diseaseKim M Fox
Cardiology Department, Royal Brompton Hospital, Sydney Street, London, UK
Am Heart J 153:629-35. 2007....
Angiotensin converting enzyme insertion/deletion polymorphism and the risk of heart failure in hypertensive subjectsAnna F C Schut
Genetic Epidemiology Unit, Department of Epidemiology, Eramus Medical Centre Rotterdam, P O Box 1738, 3000 DR Rotterdam, The Netherlands
Eur Heart J 25:2143-8. 2004..We assessed the relation between the ACE I/D polymorphism and the risk of incident heart failure in normotensive and hypertensive subjects...
ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology CommValentin Fuster
J Am Coll Cardiol 48:854-906. 2006
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology ComDouglas P Zipes
Circulation 114:e385-484. 2006
Lipoprotein-associated phospholipase A2 activity and risk of heart failure: The Rotterdam studyLaura C van Vark
Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
Eur Heart J 27:2346-52. 2006..Lipoprotein-associated phospholipase A2 (Lp-PLA2) has pro-inflammatory properties. We investigated whether Lp-PLA2 activity is associated with heart failure...
Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)Lars Ryden
Department of Cardiology, Karolinska University Hospital, Sweden
Eur Heart J 28:88-136. 2007
ACC/AHA/ESC 2006 Guidelines for the Management of Patients with Atrial Fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Valentin Fuster
Circulation 114:e257-354. 2006
Aspirin and coumadin after acute coronary syndromes (the ASPECT-2 study): a randomised controlled trialRobert F van Es
Julius Centre for General Practice and Patient Oriented Research, University Medical Centre Utrecht, Netherlands
Lancet 360:109-13. 2002....
