Robert de Jonge

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. request reprint
    de Jonge R, Hooijberg J, van Zelst B, Jansen G, Jansen G, van Zantwijk C, et al. Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia. Blood. 2005;106:717-20 pubmed
    ..SHMT1 1420TT homozygotes only showed decreased MTX sensitivity in the TSI(50, cont). In conclusion, polymorphisms in the folate-related genes MTHFR, MTRR, and SHMT1 are related to MTX resistance in pediatric patients with ALL. ..
  2. de Jonge R, Tissing W, Hooijberg J, Jansen G, Kaspers G, Lindemans J, et al. Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia. Blood. 2009;113:2284-9 pubmed publisher
    ..2-fold increase in ALL risk (P = .001). For the first time, we associate the RFC1 80G>A and NNMT IVS -151C>T variants to an increased ALL susceptibility. ..
  3. Fleming C, Russcher H, Brouwer R, Lindemans J, de Jonge R. Evaluation of Sysmex XN-1000 High-Sensitive Analysis (hsA) Research Mode for Counting and Differentiating Cells in Cerebrospinal Fluid. Am J Clin Pathol. 2016;145:299-307 pubmed publisher
    ..99) for all parameters evaluated. Carryover was negligible and never exceeded 0.04%. The XN hsA research mode provides reliable cell counts in CSF samples, even in samples containing low numbers of WBCs and RBCs. ..
  4. Herzog E, Eggink A, van der Zee M, Lagendijk J, Willemsen S, de Jonge R, et al. The impact of early- and late-onset preeclampsia on umbilical cord blood cell populations. J Reprod Immunol. 2016;116:81-5 pubmed publisher
    ..This heterogeneity in UCBC should be considered as confounder in epigenetic association studies examining EOPE. ..

Detail Information

Publications4

  1. request reprint
    de Jonge R, Hooijberg J, van Zelst B, Jansen G, Jansen G, van Zantwijk C, et al. Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia. Blood. 2005;106:717-20 pubmed
    ..SHMT1 1420TT homozygotes only showed decreased MTX sensitivity in the TSI(50, cont). In conclusion, polymorphisms in the folate-related genes MTHFR, MTRR, and SHMT1 are related to MTX resistance in pediatric patients with ALL. ..
  2. de Jonge R, Tissing W, Hooijberg J, Jansen G, Kaspers G, Lindemans J, et al. Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia. Blood. 2009;113:2284-9 pubmed publisher
    ..2-fold increase in ALL risk (P = .001). For the first time, we associate the RFC1 80G>A and NNMT IVS -151C>T variants to an increased ALL susceptibility. ..
  3. Fleming C, Russcher H, Brouwer R, Lindemans J, de Jonge R. Evaluation of Sysmex XN-1000 High-Sensitive Analysis (hsA) Research Mode for Counting and Differentiating Cells in Cerebrospinal Fluid. Am J Clin Pathol. 2016;145:299-307 pubmed publisher
    ..99) for all parameters evaluated. Carryover was negligible and never exceeded 0.04%. The XN hsA research mode provides reliable cell counts in CSF samples, even in samples containing low numbers of WBCs and RBCs. ..
  4. Herzog E, Eggink A, van der Zee M, Lagendijk J, Willemsen S, de Jonge R, et al. The impact of early- and late-onset preeclampsia on umbilical cord blood cell populations. J Reprod Immunol. 2016;116:81-5 pubmed publisher
    ..This heterogeneity in UCBC should be considered as confounder in epigenetic association studies examining EOPE. ..