Lonneke M L de Lau

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi request reprint Survival in Parkinson's disease. Relation with motor and non-motor features
    Lonneke M L de Lau
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands Department of Neurology, Slotervaart Hospital, P O Box 90440, 1006 BK Amsterdam, The Netherlands Electronic address
    Parkinsonism Relat Disord 20:613-6. 2014
  2. doi request reprint Catechol-O-methyltransferase Val158Met and the risk of dyskinesias in Parkinson's disease
    Lonneke M L de Lau
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 27:132-5. 2012
  3. doi request reprint A review of hereditary and acquired coagulation disorders in the aetiology of ischaemic stroke
    Lonneke M L de Lau
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Int J Stroke 5:385-94. 2010
  4. doi request reprint Screening for coagulation disorders in patients with ischemic stroke
    Lonneke Ml de Lau
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Expert Rev Neurother 10:1321-9. 2010
  5. doi request reprint Acute disseminating encephalomyelitis following legionnaires disease
    Lonneke M L de Lau
    Department of Neurology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
    Arch Neurol 67:623-6. 2010
  6. doi request reprint Predicting and preventing stroke after transient ischemic attack
    Lonneke M L de Lau
    Department of Neurology, Erasmus Medical Center, Rotterdam, 3000 CA Rotterdam, The Netherlands
    Expert Rev Neurother 9:1159-70. 2009
  7. doi request reprint Genetic variation in homocysteine metabolism, cognition, and white matter lesions
    Lonneke M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurobiol Aging 31:2020-2. 2010
  8. doi request reprint Acute CNS white matter lesions in patients with inflammatory bowel disease
    Lonneke M L de Lau
    Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Inflamm Bowel Dis 15:576-80. 2009
  9. ncbi request reprint Plasma folate concentration and cognitive performance: Rotterdam Scan Study
    Lonneke M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, Netherlands
    Am J Clin Nutr 86:728-34. 2007
  10. doi request reprint γ'/total fibrinogen ratio is associated with short-term outcome in ischaemic stroke
    Evita G van den Herik
    Erasmus MC University Medical Center, Department of Neurology, Rotterdam, The Netherlands
    Thromb Haemost 105:430-4. 2011

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Survival in Parkinson's disease. Relation with motor and non-motor features
    Lonneke M L de Lau
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands Department of Neurology, Slotervaart Hospital, P O Box 90440, 1006 BK Amsterdam, The Netherlands Electronic address
    Parkinsonism Relat Disord 20:613-6. 2014
    ..Survival in patients with Parkinson's disease is reduced as compared to the general population. We aimed to identify motor and non-motor features that predict mortality in Parkinson's disease...
  2. doi request reprint Catechol-O-methyltransferase Val158Met and the risk of dyskinesias in Parkinson's disease
    Lonneke M L de Lau
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 27:132-5. 2012
    ..The A-allele of the catechol-O-methyltransferase (COMT) Val158Met polymorphism is associated with decreased enzymatic activity and higher dopamine availability...
  3. doi request reprint A review of hereditary and acquired coagulation disorders in the aetiology of ischaemic stroke
    Lonneke M L de Lau
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Int J Stroke 5:385-94. 2010
    ....
  4. doi request reprint Screening for coagulation disorders in patients with ischemic stroke
    Lonneke Ml de Lau
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Expert Rev Neurother 10:1321-9. 2010
    ....
  5. doi request reprint Acute disseminating encephalomyelitis following legionnaires disease
    Lonneke M L de Lau
    Department of Neurology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands
    Arch Neurol 67:623-6. 2010
    ..To describe 2 patients presenting with severe neurological deficits and extensive lesions on brain magnetic resonance imaging after having experienced Legionella pneumonia...
  6. doi request reprint Predicting and preventing stroke after transient ischemic attack
    Lonneke M L de Lau
    Department of Neurology, Erasmus Medical Center, Rotterdam, 3000 CA Rotterdam, The Netherlands
    Expert Rev Neurother 9:1159-70. 2009
    ..In addition to the conventional vascular risk factors, interest has grown in less strong but more prevalent lifestyle factors, but trials evaluating the effect of modifying these factors are as yet lacking...
  7. doi request reprint Genetic variation in homocysteine metabolism, cognition, and white matter lesions
    Lonneke M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurobiol Aging 31:2020-2. 2010
    ..No significant relationship was observed for any of the polymorphisms with cognitive performance or severity of cerebral white matter lesions...
  8. doi request reprint Acute CNS white matter lesions in patients with inflammatory bowel disease
    Lonneke M L de Lau
    Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Inflamm Bowel Dis 15:576-80. 2009
    ..Most previous reports involve cerebral venous thrombosis, central nervous system vasculitis, or peripheral nerve inflammation...
  9. ncbi request reprint Plasma folate concentration and cognitive performance: Rotterdam Scan Study
    Lonneke M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, Netherlands
    Am J Clin Nutr 86:728-34. 2007
    ..Evidence is increasing for beneficial and independent effects of folate on cognitive function, but the underlying biologic mechanism is as yet unknown...
  10. doi request reprint γ'/total fibrinogen ratio is associated with short-term outcome in ischaemic stroke
    Evita G van den Herik
    Erasmus MC University Medical Center, Department of Neurology, Rotterdam, The Netherlands
    Thromb Haemost 105:430-4. 2011
    ..Increased fibrinogen γ' relative to total fibrinogen levels are associated with unfavourable outcome in the early phase after stroke...
  11. ncbi request reprint Subjective complaints precede Parkinson disease: the rotterdam study
    Lonneke M L de Lau
    Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Arch Neurol 63:362-5. 2006
    ..Neuronal degeneration and dopamine loss in the preclinical phase of Parkinson disease may produce subtle complaints before clinically recognizable symptoms emerge...
  12. ncbi request reprint Methylenetetrahydrofolate reductase C677T genotype and PD
    Lonneke M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Ann Neurol 57:927-30. 2005
    ..Our findings support the hypothesis that homocysteine plays a role in the pathogenesis of Parkinson's disease...
  13. doi request reprint Strongly increased levels of fibrinogen elastase degradation products in patients with ischemic stroke
    Lonneke M L de Lau
    Departments of Neurology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Br J Haematol 143:734-7. 2008
    ..Results were only slightly affected by adjustment for cardiovascular risk factors, C-reactive protein and fibrinogen. Our findings suggest that FgEDP might be involved in the pathogenesis of stroke...
  14. ncbi request reprint Prognosis of Parkinson disease: risk of dementia and mortality: the Rotterdam Study
    Lonneke M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Arch Neurol 62:1265-9. 2005
    ..Most prognostic studies on Parkinson disease have been hospital based or have applied register-based case-finding methods. Potential under-representation of mild cases may have given biased results...
  15. ncbi request reprint Relationship of Von Willebrand Factor with carotid artery and aortic arch calcification in ischemic stroke patients
    Michelle A H Sonneveld
    Department of Hematology, Erasmus MC University Medical Center, Rotterdam, The Netherlands Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Atherosclerosis 230:210-5. 2013
    ..In previous studies VWF was associated with atherosclerosis in healthy individuals. However, it is yet unknown what the association is between atherosclerosis and VWF levels in patients with ischemic stroke...
  16. ncbi request reprint Serum uric acid levels and the risk of Parkinson disease
    Lonneke M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Ann Neurol 58:797-800. 2005
    ..040). Our findings support the hypothesis that oxidative stress contributes to the risk of Parkinson disease and suggest a potential protective effect of the natural antioxidant and free radical scavenger uric acid...
  17. ncbi request reprint Serum cholesterol levels and the risk of Parkinson's disease
    Lonneke M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Epidemiol 164:998-1002. 2006
    ..If confirmed, this would provide further support for an important role of oxidative stress in the pathogenesis of Parkinson's disease...
  18. ncbi request reprint Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease
    Marjolijn Bornebroek
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neuroepidemiology 28:193-6. 2007
    ..Several lines of evidence suggest a role of inflammatory processes in Parkinson disease, although it is still unclear whether inflammation is a cause or rather a consequence of neurodegeneration...
  19. doi request reprint Association of two single nucleotide polymorphisms from genomewide association studies with clinical phenotypes of cerebral ischemia
    Evita G van den Herik
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Int J Stroke 7:219-23. 2012
    ..Recent genomewide association studies have revealed an association between two single nucleotide polymorphisms, rs11833579 and rs12425791, and ischemic stroke...
  20. pmc Rotterdam Aphasia Therapy Study (RATS)-3: "The efficacy of intensive cognitive-linguistic therapy in the acute stage of aphasia"; design of a randomised controlled trial
    Femke Nouwens
    Department of Neurology, Erasmus MC University Medical Center Rotterdam, PO Box 2040, Rotterdam, CA 3000, The Netherlands
    Trials 14:24. 2013
    ..In the Rotterdam Aphasia Therapy Study-3 we aim to test the hypothesis that patients with aphasia due to stroke benefit more from early intensive cognitive-linguistic therapy than from deferred regular language therapy...