Rogier Bodewes

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. doi request reprint Yearly influenza vaccinations: a double-edged sword?
    Rogier Bodewes
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Lancet Infect Dis 9:784-8. 2009
  2. pmc Novel B19-like parvovirus in the brain of a harbor seal
    Rogier Bodewes
    Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands
    PLoS ONE 8:e79259. 2013
  3. pmc Viral metagenomic analysis of feces of wild small carnivores
    Rogier Bodewes
    Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands
    Virol J 11:89. 2014
  4. pmc No serological evidence that harbour porpoises are additional hosts of influenza B viruses
    Rogier Bodewes
    Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands
    PLoS ONE 9:e89058. 2014
  5. pmc Identification of multiple novel viruses, including a parvovirus and a hepevirus, in feces of red foxes
    Rogier Bodewes
    Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Virol 87:7758-64. 2013
  6. doi request reprint Detection of novel divergent arenaviruses in boid snakes with inclusion body disease in The Netherlands
    R Bodewes
    Department of Viroscience, Erasmus Medical Centre, Dr Molewaterplein 50, Rotterdam, The Netherlands
    J Gen Virol 94:1206-10. 2013
  7. doi request reprint Annual influenza vaccination affects the development of heterosubtypic immunity
    Rogier Bodewes
    Department of Virology, Erasmus MC, Rotterdam, The Netherlands
    Vaccine 30:7407-10. 2012
  8. doi request reprint Use of influenza A viruses expressing reporter genes to assess the frequency of double infections in vitro
    R Bodewes
    Erasmus Medical Centre, Dr Molewaterplein 50, 3015GE Rotterdam, The Netherlands
    J Gen Virol 93:1645-8. 2012
  9. doi request reprint Animal models for the preclinical evaluation of candidate influenza vaccines
    Rogier Bodewes
    Department of Virology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Expert Rev Vaccines 9:59-72. 2010
  10. pmc Targets for the induction of protective immunity against influenza a viruses
    Rogier Bodewes
    Department of Virology, ErasmusMC, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands E Mails R B A D M E O
    Viruses 2:166-88. 2010

Collaborators

Detail Information

Publications26

  1. doi request reprint Yearly influenza vaccinations: a double-edged sword?
    Rogier Bodewes
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Lancet Infect Dis 9:784-8. 2009
    ..Preventing infection with seasonal influenza viruses by vaccination might prevent the induction of heterosubtypic immunity to pandemic strains, which might be a disadvantage to immunologically naive people-eg, infants...
  2. pmc Novel B19-like parvovirus in the brain of a harbor seal
    Rogier Bodewes
    Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands
    PLoS ONE 8:e79259. 2013
    ..These findings showed that a parvovirus of the genus Erythrovirus can be involved in central nervous system infection and inflammation, as has also been suspected but not proven for human parvovirus B19 infection. ..
  3. pmc Viral metagenomic analysis of feces of wild small carnivores
    Rogier Bodewes
    Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands
    Virol J 11:89. 2014
    ..This exemplifies the required expansion of our knowledge of the virus diversity present in wildlife, as well as the potential transmission of these viruses to domestic animals or humans...
  4. pmc No serological evidence that harbour porpoises are additional hosts of influenza B viruses
    Rogier Bodewes
    Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands
    PLoS ONE 9:e89058. 2014
    ..No antibodies were detected against either virus, suggesting that influenza A and B virus infections of harbour porpoises in Dutch coastal waters are not common, which was supported by statistical analysis of the dataset. ..
  5. pmc Identification of multiple novel viruses, including a parvovirus and a hepevirus, in feces of red foxes
    Rogier Bodewes
    Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Virol 87:7758-64. 2013
    ..Various novel viruses, including a parvovirus, bocavirus, adeno-associated virus, hepevirus, astroviruses, and picobirnaviruses, were identified...
  6. doi request reprint Detection of novel divergent arenaviruses in boid snakes with inclusion body disease in The Netherlands
    R Bodewes
    Department of Viroscience, Erasmus Medical Centre, Dr Molewaterplein 50, Rotterdam, The Netherlands
    J Gen Virol 94:1206-10. 2013
    ..These findings add to the recent identification of the highly divergent arenaviruses in boid snakes with IBD in the United States and indicate that these viruses also circulate among boid snakes in Europe...
  7. doi request reprint Annual influenza vaccination affects the development of heterosubtypic immunity
    Rogier Bodewes
    Department of Virology, Erasmus MC, Rotterdam, The Netherlands
    Vaccine 30:7407-10. 2012
    ..These findings highlight the importance of the development of vaccines that provide protection against influenza A viruses of all subtypes...
  8. doi request reprint Use of influenza A viruses expressing reporter genes to assess the frequency of double infections in vitro
    R Bodewes
    Erasmus Medical Centre, Dr Molewaterplein 50, 3015GE Rotterdam, The Netherlands
    J Gen Virol 93:1645-8. 2012
    ..Double-infected A549 and Madin-Darby canine kidney cells were detected by confocal microscopy and flow cytometry...
  9. doi request reprint Animal models for the preclinical evaluation of candidate influenza vaccines
    Rogier Bodewes
    Department of Virology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Expert Rev Vaccines 9:59-72. 2010
    ..Commonly, vaccines are tested for safety and efficacy in mice, ferrets and/or macaques. The use of each of these species has its advantages and limitations, which are addressed here...
  10. pmc Targets for the induction of protective immunity against influenza a viruses
    Rogier Bodewes
    Department of Virology, ErasmusMC, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands E Mails R B A D M E O
    Viruses 2:166-88. 2010
    ....
  11. pmc Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets
    Judith M A van den Brand
    Department of Virology, Erasmus Medical Center, P O Box 2040, 3000 CA Rotterdam, Netherlands
    J Virol 85:2851-8. 2011
    ....
  12. ncbi request reprint Vaccination with whole inactivated virus vaccine affects the induction of heterosubtypic immunity against influenza virus A/H5N1 and immunodominance of virus-specific CD8+ T-cell responses in mice
    Rogier Bodewes
    Department of Virology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Gen Virol 91:1743-53. 2010
    ..These findings may have implications for vaccination strategies aimed at the induction of protective immunity to seasonal and/or pandemic influenza...
  13. pmc Infection of the upper respiratory tract with seasonal influenza A(H3N2) virus induces protective immunity in ferrets against infection with A(H1N1)pdm09 virus after intranasal, but not intratracheal, inoculation
    Rogier Bodewes
    Viroscience Lab, Erasmus MC, Rotterdam, Netherlands
    J Virol 87:4293-301. 2013
    ..These findings are of interest in light of the development of so-called universal influenza vaccines that aim at the induction of cross-reactive T cell responses...
  14. pmc Vaccination against human influenza A/H3N2 virus prevents the induction of heterosubtypic immunity against lethal infection with avian influenza A/H5N1 virus
    Rogier Bodewes
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    PLoS ONE 4:e5538. 2009
    ..These findings may have implications for the general recommendation to vaccinate all healthy children against seasonal influenza in the light of the current pandemic threat caused by highly pathogenic avian A/H5N1 influenza viruses...
  15. pmc Metagenomic analysis of the ferret fecal viral flora
    Saskia L Smits
    Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands Viroclinics Biosciences BV, Rotterdam, The Netherlands
    PLoS ONE 8:e71595. 2013
    ..Our studies illuminate the viral diversity found in ferrets and provide tools to prescreen for newly identified viruses that potentially could influence disease outcome of experimental virus infections in ferrets. ..
  16. pmc Pathogenesis of Influenza A/H5N1 virus infection in ferrets differs between intranasal and intratracheal routes of inoculation
    Rogier Bodewes
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Pathol 179:30-6. 2011
    ..The method of virus inoculation requires careful consideration in the design of ferret experiments as a model for influenza A/H5N1 in humans...
  17. doi request reprint Cross-protective immunity against influenza pH1N1 2009 viruses induced by seasonal influenza A (H3N2) virus is mediated by virus-specific T-cells
    Marine L B Hillaire
    Erasmus Medical Centre, Rotterdam, The Netherlands
    J Gen Virol 92:2339-49. 2011
    ....
  18. doi request reprint Evaluation of a modified vaccinia virus Ankara (MVA)-based candidate pandemic influenza A/H1N1 vaccine in the ferret model
    Joost H C M Kreijtz
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Gen Virol 91:2745-52. 2010
    ..In contrast, two immunizations induced robust antibody responses and protected ferrets from developing severe disease, confirming that MVA is an attractive influenza vaccine production platform...
  19. ncbi request reprint Pediatric influenza vaccination: understanding the T-cell response
    Rogier Bodewes
    Department of Virology, Erasmus MC, Rotterdam, The Netherlands
    Expert Rev Vaccines 11:963-71. 2012
    ..The authors discuss these findings in the light of developing vaccines and vaccination strategies aiming at the induction of protective immunity to seasonal and pandemic influenza viruses of antigenically distinct subtypes...
  20. pmc Annual vaccination against influenza virus hampers development of virus-specific CD8⁺ T cell immunity in children
    Rogier Bodewes
    Department of Virology, Erasmus Medical Center, Dr Molewaterplein 50, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Virol 85:11995-2000. 2011
    ..The consequences of these findings are discussed in the light of the development of protective immunity to seasonal and future pandemic influenza viruses...
  21. pmc Identification and characterization of two novel viruses in ocular infections in reindeer
    Saskia L Smits
    ViroClinics BioSciences BV, Rotterdam, The Netherlands
    PLoS ONE 8:e69711. 2013
    ..Whether either virus was responsible for causing the clinical signs or in any respect was associated to the disease condition remains to be determined. ..
  22. pmc In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza a virus nucleoprotein
    Rogier Bodewes
    Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands
    Clin Vaccine Immunol 20:1333-7. 2013
    ....
  23. pmc The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets
    Eefje J A Schrauwen
    National Influenza Center and Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Virol 86:3975-84. 2012
    ..In conclusion, HPAI H5N1 virus can spread systemically via two different routes, olfactory and hematogenous, in ferrets. This systemic spread was dependent on the presence of the MBCS in HA...
  24. doi request reprint Vaccination strategies to protect children against seasonal and pandemic influenza
    Guus F Rimmelzwaan
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Vaccine 29:7551-3. 2011
    ..This would afford protection through maternally derived antibodies. In addition, vaccination of close family members of young infants is recommended, to prevent transmission within the household...
  25. doi request reprint The ins and outs of universal childhood influenza vaccination
    Pieter L A Fraaij
    Department of Virology, Erasmus Medical Centre, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Future Microbiol 6:1171-84. 2011
    ....
  26. ncbi request reprint Influenza virus CTL epitopes, remarkably conserved and remarkably variable
    Guus F Rimmelzwaan
    Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands
    Vaccine 27:6363-5. 2009
    ..A mutational analysis of this epitope indicated that it is under functional constraints. Also in influenza A viruses of other subtypes, including H5N1, the M1(58-66) is highly conserved...