Research Topics
Species | Hetty BlaakSummaryAffiliation: Erasmus MC Country: The Netherlands Publications
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Detail Information
Publications
HIV-2-infected individuals with undetectable plasma viremia carry replication-competent virus in peripheral blood lymphocytesHetty Blaak
Department of Virology, Erasmus MC, Rotterdam, The Netherlands
J Acquir Immune Defic Syndr 36:777-82. 2004..88, P < 0.0001). The low infectious load in aviremic HIV-2-infected persons is reminiscent of what has been observed for HIV-1 infection controlled by highly active antiretroviral therapy...
CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremiaH Blaak
Department of Virology, Room Ee1742a, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands
J Virol 79:1686-700. 2005..Broad coreceptor usage, therefore, does not appear to be associated with pathogenicity of HIV-2...
In vitro replication capacity of HIV-2 variants from long-term aviremic individualsHetty Blaak
Department of Virology, Erasmus Medical Center Erasmus MC, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
Virology 353:144-54. 2006..The relatively low replicative capacity of HIV-2 variants from aviremic individuals likely contributes to the low viral load and benign course of infection in these individuals...
CCR5-restricted HIV type 2 variants from long-term aviremic individuals are less sensitive to inhibition by beta-chemokines than low pathogenic HIV type 1 variantsHetty Blaak
Department of Virology, Erasmus Medical Center Erasmus MC, Rotterdam, The Netherlands
AIDS Res Hum Retroviruses 24:473-84. 2008....
Isolation of human immunodeficiency virus type 2 biological clones from peripheral blood lymphocytesHetty Blaak
Department of Virology, Erasmus MC, Rotterdam, The Netherlands
Methods Mol Biol 304:95-112. 2005..In addition, the frequency of PBMC infected with HIV-2 variants capable of propagating in vitro can be estimated...
Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infectionMelody G Duvall
MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom
J Virol 81:13486-98. 2007....
