Marcel J C Bijvelds
Affiliation: Erasmus MC
Country: The Netherlands
- Fat absorption in cystic fibrosis mice is impeded by defective lipolysis and post-lipolytic eventsMarcel J C Bijvelds
Dept of Biochemistry, Erasmus MC, Postbus 1738, NL 3000 DR Rotterdam, The Netherlands
Am J Physiol Gastrointest Liver Physiol 288:G646-53. 2005..We conclude that fat malabsorption in cftr null mice is caused by impairment of lipolysis, which may result from aberrant duodenal pH regulation...
- Activation of CFTR by ASBT-mediated bile salt absorptionMarcel J C Bijvelds
Dept of Biochemistry, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands
Am J Physiol Gastrointest Liver Physiol 289:G870-9. 2005..We conclude that active BS absorption in the ileum triggers CFTR activation and, consequently, local salt and water secretion, which may serve to prevent intestinal obstruction in the postprandial state...
- Activation of intestinal Cl- secretion by lubiprostone requires the cystic fibrosis transmembrane conductance regulatorMarcel J C Bijvelds
Department of Biochemistry, Sophia Children s Hospital, Erasmus MC, Rotterdam, The Netherlands
Gastroenterology 137:976-85. 2009..Because ClC-2 recruitment might be beneficial to CF patients, we investigated lubiprostone's mode of action...