Alejandro Arias-Vasquez

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc No evidence for association between tau gene haplotypic variants and susceptibility to Creutzfeldt-Jakob disease
    Pascual Sanchez-Juan
    Institute for Formation and Research of the Fundación Marqués de Valdecilla IFIMAV, Santander, Spain
    BMC Med Genet 8:77. 2007
  2. ncbi A deletion in DJ-1 and the risk of dementia--a population-based survey
    Alejandro Arias Vasquez
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Neurosci Lett 372:196-9. 2004
  3. ncbi Angiotensin converting enzyme gene, smoking and mortality in a population-based study
    A Arias-Vasquez
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC Rotterdam, Netherlands
    Eur J Clin Invest 35:444-9. 2005
  4. ncbi Relationship of the Ubiquilin 1 gene with Alzheimer's and Parkinson's disease and cognitive function
    Alejandro Arias-Vasquez
    Epidemiology and Biostatistics Department, Erasmus MC, Rotterdam, The Netherlands
    Neurosci Lett 424:1-5. 2007
  5. ncbi The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease
    Alejandro Arias-Vasquez
    Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Neurogenetics 8:189-93. 2007
  6. doi Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study
    Alejandro Arias-Vasquez
    Genetic Epidemiology Unit, Dept of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Neurol 255:655-62. 2008
  7. pmc A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population
    Fan Liu
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics and Clinical Genetics, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Am J Hum Genet 81:17-31. 2007
  8. ncbi Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk
    Angela M González-Zuloeta Ladd
    Epidemiology and Biostatistics Department, Erasmus Medical Center, Rotterdam, The Netherlands
    Cancer Epidemiol Biomarkers Prev 14:2143-6. 2005
  9. ncbi Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk
    Marie Josee E van Rijn
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Stroke 37:2930-4. 2006
  10. ncbi Transforming-growth factor beta1 Leu10Pro polymorphism and breast cancer morbidity
    A M González-Zuloeta Ladd
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Postbus 1738, 3000 DR Rotterdam, The Netherlands
    Eur J Cancer 43:371-4. 2007

Detail Information

Publications15

  1. pmc No evidence for association between tau gene haplotypic variants and susceptibility to Creutzfeldt-Jakob disease
    Pascual Sanchez-Juan
    Institute for Formation and Research of the Fundación Marqués de Valdecilla IFIMAV, Santander, Spain
    BMC Med Genet 8:77. 2007
    ..However, there is increasing evidence that other loci outside the PRNP open reading frame might play a role in CJD aetiology as well...
  2. ncbi A deletion in DJ-1 and the risk of dementia--a population-based survey
    Alejandro Arias Vasquez
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Neurosci Lett 372:196-9. 2004
    ..All subjects were heterozygous for the deletion and related to a common ancestor within eight generations. Our results suggest it is unlikely that haploinsufficiency in the DJ-1 gene imparts an increased risk for dementia...
  3. ncbi Angiotensin converting enzyme gene, smoking and mortality in a population-based study
    A Arias-Vasquez
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC Rotterdam, Netherlands
    Eur J Clin Invest 35:444-9. 2005
    ..We aimed to evaluate if the ACE I/D polymorphism is related to total mortality in the elderly...
  4. ncbi Relationship of the Ubiquilin 1 gene with Alzheimer's and Parkinson's disease and cognitive function
    Alejandro Arias-Vasquez
    Epidemiology and Biostatistics Department, Erasmus MC, Rotterdam, The Netherlands
    Neurosci Lett 424:1-5. 2007
    ..Our results suggest that it is unlikely that the SNP rs12344615 of the UBQLN1 gene is related to the onset of AD, PD or cognitive function...
  5. ncbi The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease
    Alejandro Arias-Vasquez
    Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Neurogenetics 8:189-93. 2007
    ..04). Our results suggest that the VV genotype of the I405V polymorphism of the CETP gene increases the risk of AD in the absence of the APOE*4 allele, probably through a cholesterol metabolism pathway in the brain...
  6. doi Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study
    Alejandro Arias-Vasquez
    Genetic Epidemiology Unit, Dept of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Neurol 255:655-62. 2008
    ..In our analysis, the haplotype tagged by the G allele of SNP rs2069442 was significantly associated with AD (p = 0.05). In conclusion, our study suggests that CDK5 may be associated with AD...
  7. pmc A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population
    Fan Liu
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics and Clinical Genetics, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Am J Hum Genet 81:17-31. 2007
    ..For this region, our analysis identified the NMNAT3 and CLSTN2 genes. Our findings confirm linkage to chromosome 11q25. We were unable to confirm SORL1; instead, our analysis points to the OPCML and HNT genes...
  8. ncbi Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk
    Angela M González-Zuloeta Ladd
    Epidemiology and Biostatistics Department, Erasmus Medical Center, Rotterdam, The Netherlands
    Cancer Epidemiol Biomarkers Prev 14:2143-6. 2005
    ..The use of ACE inhibitors and the ACE I/D polymorphism may be linked to breast cancer risk. In this study, we evaluate the relationship of the ACE I/D polymorphism with breast cancer risk in Caucasian postmenopausal women...
  9. ncbi Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk
    Marie Josee E van Rijn
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Stroke 37:2930-4. 2006
    ..We studied the association between the Gly460Trp polymorphism and atherosclerosis, cardiovascular disease, and cerebrovascular disease...
  10. ncbi Transforming-growth factor beta1 Leu10Pro polymorphism and breast cancer morbidity
    A M González-Zuloeta Ladd
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Postbus 1738, 3000 DR Rotterdam, The Netherlands
    Eur J Cancer 43:371-4. 2007
    ..4, 95% CI=1.1-2.0) against non-carriers. Our data suggest that the TGF-beta1 Leu10Pro polymorphism might play a role in breast cancer risk...
  11. ncbi Differential roles of Angiotensinogen and Angiotensin Receptor type 1 polymorphisms in breast cancer risk
    A M González-Zuloeta Ladd
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Postbus 1738, 3000 DR, Rotterdam, The Netherlands
    Breast Cancer Res Treat 101:299-304. 2007
    ..Our results suggest that AGT plays a role in breast cancer risk in postmenopausal women, whereas the role of AGTR1 needs further studying...
  12. ncbi IGF-1 CA repeat variant and breast cancer risk in postmenopausal women
    A M González-Zuloeta Ladd
    Epidemiology and Biostatistics Department, Erasmus MC, Rotterdam, The Netherlands
    Eur J Cancer 43:1718-22. 2007
    ..26 (95% CI=0.95-1.82) for IGF-I CA(19) non-carriers versus CA(19) homozygous carriers. According to these results, the IGF-I CA(19) promoter polymorphism is not likely to predict the risk of breast cancer...
  13. ncbi Interleukin 6 G-174 C polymorphism and breast cancer risk
    A M González-Zuloeta Ladd
    Department of Epidemiology and Biostatistics Department, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Epidemiol 21:373-6. 2006
    ..This increased risk was not statistically significant. Our data suggest that the IL-6 G-174 C polymorphism does not seem to play a role in breast cancer risk, although its role as a prognostic factor remains to be studied...
  14. pmc Polymorphisms of the renin-angiotensin system are associated with blood pressure, atherosclerosis and cerebral white matter pathology
    M J E van Rijn
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 78:1083-7. 2007
    ..We studied the association between the M235T polymorphism of the angiotensinogen gene (AGT) and the C573T polymorphism of the angiotensin II type 1 receptor (AT1R) and blood pressure, carotid atherosclerosis and cerebrovascular disease...
  15. ncbi The impact of apolipoprotein E on dementia in persons with Down's syndrome
    A M W Coppus
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Neurobiol Aging 29:828-35. 2008
    ..94). When pooling our data in a meta-analysis, the APOE epsilon4 allele shows a 1.59-fold (95%CI: 1.19-2.12) increase in risk of dementia in persons with DS. We conclude that APOE is influencing the risk of dementia in persons with DS...