A Amelink

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi Single-scattering spectroscopy for the endoscopic analysis of particle size in superficial layers of turbid media
    Arjen Amelink
    Erasmus MC, P O Box 5201, 3008 AE Rotterdam, The Netherlands
    Appl Opt 42:4095-101. 2003
  2. doi Non-invasive measurement of the microvascular properties of non-dysplastic and dysplastic oral leukoplakias by use of optical spectroscopy
    A Amelink
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Oral Oncol 47:1165-70. 2011
  3. pmc The future of medical diagnostics: review paper
    Waseem K Jerjes
    Head and Neck Optical Diagnostics Society Council, International Society of Minimally Invasive Diagnostics, University College London, London, UK
    Head Neck Oncol 3:38. 2011
  4. doi In vivo measurement of bladder wall oxygen saturation using optical spectroscopy
    Arjen Amelink
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Biophotonics 4:715-20. 2011
  5. doi Noninvasive measurement of oxygen saturation of the microvascular blood in Barrett's dysplasia by use of optical spectroscopy
    Arjen Amelink
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Gastrointest Endosc 70:1-6. 2009
  6. doi Quantitative fluorescence spectroscopy in turbid media using fluorescence differential path length spectroscopy
    Arjen Amelink
    Erasmus Medical Centre Rotterdam, Department of Radiation Oncology, Center for Optical Diagnostics and Therapy, Rotterdam, The Netherlands 3000 CA
    J Biomed Opt 13:054051. 2008
  7. doi Confidence intervals on fit parameters derived from optical reflectance spectroscopy measurements
    Arjen Amelink
    Erasmus Medical Centre Rotterdam, Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, 3000 CA Rotterdam, The Netherlands
    J Biomed Opt 13:054044. 2008
  8. ncbi Controlling the optical path length in turbid media using differential path-length spectroscopy: fiber diameter dependence
    O P Kaspers
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands
    Appl Opt 47:365-71. 2008
  9. ncbi Monitoring PDT by means of superficial reflectance spectroscopy
    A Amelink
    Department of Radiation Oncology, Center for Optical Diagnostics and Therapy, Room Wk 308, Erasmus MC, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Photochem Photobiol B 79:243-51. 2005
  10. ncbi Measurement of the local optical properties of turbid media by differential path-length spectroscopy
    Arjen Amelink
    Department of Radiation Oncology, Erasmus Medical Center, P O Box 5201, 3008 AE Rotterdam, The Netherlands
    Appl Opt 43:3048-54. 2004

Collaborators

  • Martin P Bard
  • Dominic J Robinson
  • Joachim G J V Aerts
  • Slavka Kascakova
  • Bastiaan Kruijt
  • Stephen Chad Kanick
  • U A Gamm
  • H J C M Sterenborg
  • F van Leeuwen-van Zaane
  • C L Hoy
  • C van der Leest
  • Waseem K Jerjes
  • O P Kaspers
  • Robert L P van Veen
  • P B A A Van Driel
  • C W G M Lowik
  • T J A Snoeks
  • H S de Bruijn
  • A van der Ploeg-van den Heuvel
  • I M Mol
  • H C Hoogsteden
  • R J van Klaveren
  • Christian S Betz
  • Anil K D'Cruz
  • Rebecca Richards-Kortum
  • Catherine Kendall
  • Khee C Soo
  • Justus F Ilgner
  • Herbert Stepp
  • Ann Sandison
  • Zhongping Chen
  • Lina Bolotine
  • Katarina Svanberg
  • Herbert Wolfsen
  • Charles A Mosse
  • Robert van Veen
  • Malini Olivo
  • Merrill A Biel
  • Andreas Leunig
  • Lin Ping Choo-Smith
  • Kristian Berg
  • Arjun G Yodh
  • Alexander J MacRobert
  • Brian J Wong
  • Colin Hopper
  • Irving Bigio
  • Henricus J Sterenborg
  • Adel K El-Naggar
  • Max J Witjes
  • Vanderlei Bagnato
  • Nicholas Stone
  • I Bing Tan
  • Jennifer Rosen
  • Brian C Wilson
  • Tahwinder Upile
  • Hugh Barr
  • Gordon McKenzie
  • Ann Gillenwater
  • Marian Menke-Pluymers
  • Carmen van der Pol
  • Henricus J C M Sterenborg

Detail Information

Publications33

  1. ncbi Single-scattering spectroscopy for the endoscopic analysis of particle size in superficial layers of turbid media
    Arjen Amelink
    Erasmus MC, P O Box 5201, 3008 AE Rotterdam, The Netherlands
    Appl Opt 42:4095-101. 2003
    ..Several tissue phantoms demonstrated our fiber-optic probes sensitivity to light scattering from superficial layers of tissue and thereby its potential to detect superficial precancerous epithelial lesions...
  2. doi Non-invasive measurement of the microvascular properties of non-dysplastic and dysplastic oral leukoplakias by use of optical spectroscopy
    A Amelink
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Oral Oncol 47:1165-70. 2011
    ....
  3. pmc The future of medical diagnostics: review paper
    Waseem K Jerjes
    Head and Neck Optical Diagnostics Society Council, International Society of Minimally Invasive Diagnostics, University College London, London, UK
    Head Neck Oncol 3:38. 2011
    ..The meeting included 2 sections: oral communication sessions running in parallel to the IPA programme and poster presentation sessions combined with the IPA and EPPM posters sessions...
  4. doi In vivo measurement of bladder wall oxygen saturation using optical spectroscopy
    Arjen Amelink
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Biophotonics 4:715-20. 2011
    ..In the present paper, we report on the first in vivo measurement of this marker in the human bladder, as proof of principle, in the muscle of bladders with a normal function...
  5. doi Noninvasive measurement of oxygen saturation of the microvascular blood in Barrett's dysplasia by use of optical spectroscopy
    Arjen Amelink
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Gastrointest Endosc 70:1-6. 2009
    ..Adjustment of the center wavelength, particularly of the NBI blue imaging filter, may lead to improved image contrast, depending on the oxygen saturation of the microvascular blood of dysplastic and early cancerous Barrett's mucosa...
  6. doi Quantitative fluorescence spectroscopy in turbid media using fluorescence differential path length spectroscopy
    Arjen Amelink
    Erasmus Medical Centre Rotterdam, Department of Radiation Oncology, Center for Optical Diagnostics and Therapy, Rotterdam, The Netherlands 3000 CA
    J Biomed Opt 13:054051. 2008
    ..The differential fluorescence signal is attenuated due to absorption at the excitation wavelength following Lambert-Beer's law with a path length equal to the differential path length...
  7. doi Confidence intervals on fit parameters derived from optical reflectance spectroscopy measurements
    Arjen Amelink
    Erasmus Medical Centre Rotterdam, Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, 3000 CA Rotterdam, The Netherlands
    J Biomed Opt 13:054044. 2008
    ..We investigate the use of various methods to identify and subsequently minimize the bias in the fitted parameters associated with incorrect modeling...
  8. ncbi Controlling the optical path length in turbid media using differential path-length spectroscopy: fiber diameter dependence
    O P Kaspers
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands
    Appl Opt 47:365-71. 2008
    ..An empirical model is formulated that relates the DPS path length to total absorption for all fiber diameters simultaneously...
  9. ncbi Monitoring PDT by means of superficial reflectance spectroscopy
    A Amelink
    Department of Radiation Oncology, Center for Optical Diagnostics and Therapy, Room Wk 308, Erasmus MC, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Photochem Photobiol B 79:243-51. 2005
    ..These results yield valuable insight in the behavior of these parameters during PDT and their suitability to predict PDT-response for other photosensitizers for which monitoring through photobleaching is not possible...
  10. ncbi Measurement of the local optical properties of turbid media by differential path-length spectroscopy
    Arjen Amelink
    Department of Radiation Oncology, Erasmus Medical Center, P O Box 5201, 3008 AE Rotterdam, The Netherlands
    Appl Opt 43:3048-54. 2004
    ..This effect is nearly independent of the optical properties of the sample under investigation...
  11. ncbi In vivo measurement of the local optical properties of tissue by use of differential path-length spectroscopy
    Arjen Amelink
    Department of Radiation Oncology, Erasmus Medical Centre, P O Box 5201, 3008 AE Rotterdam, The Netherlands
    Opt Lett 29:1087-9. 2004
    ..Our data collected to date show that cancerous bronchial mucosa has a lower capillary oxygenation and a larger average capillary diameter than normal bronchial mucosa...
  12. doi Monte Carlo analysis of single fiber reflectance spectroscopy: photon path length and sampling depth
    S C Kanick
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Phys Med Biol 54:6991-7008. 2009
    ....
  13. ncbi Non-invasive measurement of the morphology and physiology of oral mucosa by use of optical spectroscopy
    A Amelink
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Centre, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Oral Oncol 44:65-71. 2008
    ....
  14. ncbi Characterization of mediastinal lymph node physiology in vivo by optical spectroscopy during endoscopic ultrasound-guided fine needle aspiration
    Stephen C Kanick
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus MC, University Hospital, Rotterdam, The Netherlands
    J Thorac Oncol 5:981-7. 2010
    ....
  15. doi In vivo quantification of chromophore concentration using fluorescence differential path length spectroscopy
    Bastiaan Kruijt
    Centre for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus MC Room Ee1675, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Biomed Opt 14:034022. 2009
    ..2 mm(3) and approximately 10(2) mm(3), respectively. This indicates intra-animal variation in m-THPC distribution in the liver on the scale of the FDPS sampling volume...
  16. doi Quantification of the reduced scattering coefficient and phase-function-dependent parameter γ of turbid media using multidiameter single fiber reflectance spectroscopy: experimental validation
    U A Gamm
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Opt Lett 37:1838-40. 2012
    ....
  17. doi Monitoring interstitial m-THPC-PDT in vivo using fluorescence and reflectance spectroscopy
    Bastiaan Kruijt
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus MC, Rotterdam, The Netherlands
    Lasers Surg Med 41:653-64. 2009
    ..These parameters are monitored during PDT without interrupting the therapeutic illumination...
  18. pmc Measurement of tissue scattering properties using multi-diameter single fiber reflectance spectroscopy: in silico sensitivity analysis
    U A Gamm
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Biomed Opt Express 2:3150-66. 2011
    ..Moreover, accurate parameter estimates were obtained without a priori knowledge about the spectral shape of γ. Observations were used to develop heuristic guidelines for the design of clinically applicable MDSFR probes...
  19. doi Integration of single-fiber reflectance spectroscopy into ultrasound-guided endoscopic lung cancer staging of mediastinal lymph nodes
    Stephen Chad Kanick
    Erasmus Medical Center, Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Rotterdam, The Netherlands
    J Biomed Opt 15:017004. 2010
    ..The data show the feasibility of this novel technique; however, the potential clinical utility has yet to be determined...
  20. ncbi Optical spectroscopy for the classification of malignant lesions of the bronchial tree
    Martin P L Bard
    Department of Respiratory Diseases, Sint Franciscus Hospital, Kleiweg 500, 3045 PM, Rotterdam, The Netherlands
    Chest 129:995-1001. 2006
    ..Even better results were obtained when the three spectroscopic techniques were combined...
  21. ncbi Improving the specificity of fluorescence bronchoscopy for the analysis of neoplastic lesions of the bronchial tree by combination with optical spectroscopy: preliminary communication
    Martin P L Bard
    Department of Respiratory Diseases, Erasmus Medical Center, H Ee2253a, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Lung Cancer 47:41-7. 2005
    ..We will show in this preliminary report that the addition of either of these spectroscopic techniques decreases the rate of false positives findings, with the best results obtained when both spectroscopic modalities are combined...
  22. doi Empirical model description of photon path length for differential path length spectroscopy: combined effect of scattering and absorption
    Stephen C Kanick
    Erasmus Medical Center, Department of Radiation Oncology, Center for Optical Diagnostics and Therapy, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Biomed Opt 13:064042. 2008
    ..This novel relationship is applicable to analysis of DPS measurements of tissue in both the UV/VIS and NIR wavelength regions and may provide information about the wavelength-specific tissue volume optically sampled during measurement...
  23. ncbi Measurement of hypoxia-related parameters in bronchial mucosa by use of optical spectroscopy
    Martin P L Bard
    Department of Respiratory Diseases, Center for Optical Diagnostics and Therapy, Rotterdam, Netherlands
    Am J Respir Crit Care Med 171:1178-84. 2005
    ..We developed a novel noninvasive technique, differential path-length spectroscopy (DPS), which allows the measurement of hypoxia-related parameters in the superficial microvasculature of tissue...
  24. doi Ex vivo quantification of mTHPC concentration in tissue: influence of chemical extraction on the optical properties
    Slavka Kascakova
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, Westzeedijk 118, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Photochem Photobiol B 91:99-107. 2008
    ..This implies that for the correct quantification of photosensitizer concentrations, the fluorescence of native tissue chromophores must be accounted for...
  25. pmc Use of a coherent fiber bundle for multi-diameter single fiber reflectance spectroscopy
    C L Hoy
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Biomed Opt Express 3:2452-64. 2012
    ..Based on these results, the coherent fiber bundle is suitable for use as a variable-diameter fiber in clinical MDSFR quantification of tissue optical properties...
  26. pmc Semi-empirical model of the effect of scattering on single fiber fluorescence intensity measured on a turbid medium
    S C Kanick
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Biomed Opt Express 3:137-52. 2012
    ..999) over the investigated range of μ'(s)(λ(x)) and μ'(s)(λ(m)), is insensitive to the form of the P(θ), and provides novel insight into a dimensionless relationship linking F(SF) measured by different d(f)...
  27. pmc Measurement of the reduced scattering coefficient of turbid media using single fiber reflectance spectroscopy: fiber diameter and phase function dependence
    S C Kanick
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Biomed Opt Express 2:1687-702. 2011
    ..This calibrated technique provides accurate estimates of μs' over a wide range ([0.05 - 8] mm(-1)) for a range of d(fib) ([0.2 - 1] mm)...
  28. doi A dedicated applicator for light delivery and monitoring of PDT of intra-anal intraepithelial neoplasia
    Bastiaan Kruijt
    Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus MC, Rotterdam, The Netherlands
    Photodiagnosis Photodyn Ther 7:3-9. 2010
    ..Furthermore this study shows the possibility of monitoring blood saturation, blood volume, fluorescence and fluence (rate) during therapeutic illumination without changing the light treatment protocol...
  29. ncbi Effect of hemoglobin extinction spectra on optical spectroscopic measurements of blood oxygen saturation
    Arjen Amelink
    Department of Radiation Oncology, Center for Optical Diagnostics and Therapy, Erasmus MC, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Opt Lett 34:1525-7. 2009
    ..Depending on the choice of hemoglobin extinction spectra the absolute deviation between the ODC and the optically extracted SO(2) is less than 2.5% over the measured range of saturations (4%-99%)...
  30. ncbi Optical biopsy of breast tissue using differential path-length spectroscopy
    Robert L P van Veen
    Department of Radiation Oncology, Center for Optical Diagnostics and Therapy, Erasmus Medical Center Rotterdam, PO Box 5201, 3008 AE Rotterdam, The Netherlands
    Phys Med Biol 50:2573-81. 2005
    ..Our data show that malignant breast tissue is characterized by a significant decrease in tissue oxygenation and a higher blood content compared to normal breast tissue...
  31. pmc In vivo quantification of the scattering properties of tissue using multi-diameter single fiber reflectance spectroscopy
    F van Leeuwen-van Zaane
    Department of Radiation Oncology, Center for Optical Diagnostics and Therapy, Postgraduate School Molecular Medicine, Erasmus MC, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Biomed Opt Express 4:696-708. 2013
    ..72 ± 0.09) than normal tongue (1.58 ± 0.07). This study shows the potential of using light scattering spectroscopy to optically characterize tissue in vivo...
  32. pmc Optical detection of preneoplastic lesions of the central airways
    C van der Leest
    Department of Respiratory Diseases, Erasmus Medical Center, Postbus 2040, 3000 CA Rotterdam, The Netherlands
    ISRN Oncol 2012:957835. 2012
    ..In this review we highlight the technological developments in the field of endoscopic imaging, and describe their advantages and disadvantages in clinical use...
  33. doi Monitoring ALA-induced PpIX photodynamic therapy in the rat esophagus using fluorescence and reflectance spectroscopy
    Bastiaan Kruijt
    Department of Radiation Oncology, Centre for Optical Diagnostics and Therapy, Erasmus MC, Rotterdam, The Netherlands
    Photochem Photobiol 84:1515-27. 2008
    ....