Affiliation: Eindhoven University of Technology
Country: The Netherlands
- A new MR-compatible loading device to study in vivo muscle damage development in rats due to compressive loadingA Stekelenburg
Department of Materials Technology, Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
Med Eng Phys 28:331-8. 2006..With this new set-up, the different factors that may play a role in the onset of muscle damage can be studied, what we believe will lead to a better understanding of the contributing factors to pressure ulcer development...
- Compression-induced deep tissue injury examined with magnetic resonance imaging and histologyA Stekelenburg
Eindhoven University of Technology, Department of Materials Technology, PO Box 513, Den Dolech 2, 5600 MB Eindhoven, The Netherlands
J Appl Physiol 100:1946-54. 2006..Differences in damage development distal and proximal to the indenter position suggested a contribution of perfusion status in the measured tissue changes that, however, appeared be to reversible...
- Role of ischemia and deformation in the onset of compression-induced deep tissue injury: MRI-based studies in a rat modelAnke Stekelenburg
Dept of Biomedical Engineering, Eindhoven University of Technology, Den Dolech 2, 5600 MB Eindhoven, The Netherlands
J Appl Physiol 102:2002-11. 2007..0. There was a good correlation between the location of damage and the location of high shear strain. It was concluded that the large deformations, in conjunction with ischemia, provided the main trigger for irreversible muscle damage...
- Deep tissue injury: how deep is our understanding?Anke Stekelenburg
Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
Arch Phys Med Rehabil 89:1410-3. 2008..Deformation levels exceeding a threshold value can result in rapid tissue damage that may persist, whereas ischemia has a more gradual effect as a result of glucose depletion and tissue acidification...
- Validation of a numerical model of skeletal muscle compression with MR tagging: a contribution to pressure ulcer researchK K Ceelen
Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
J Biomech Eng 130:061015. 2008..It was concluded that the model was suitable for calculating strains in skeletal muscle tissues in which damage is measured due to compression...
- Temporal effects of mechanical loading on deformation-induced damage in skeletal muscle tissueS Loerakker
Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, Building W Hoog 4 108, 5600 MB, Eindhoven, The Netherlands
Ann Biomed Eng 38:2577-87. 2010..Temporary load reliefs were inefficient in reducing deformation-induced damage, but may still influence the development of ischemia-induced damage during longer loading periods...
- Compression-induced damage and internal tissue strains are relatedK K Ceelen
Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, Building W hoog 4 11, 5600 MB Eindhoven, The Netherlands
J Biomech 41:3399-404. 2008..Using dedicated finite element modeling, a considerable reduction in the inherent biological variation was obtained, leading to the proposal that muscle deformation can prove a generic predictive indicator of damage...
- Passive transverse mechanical properties as a function of temperature of rat skeletal muscle in vitroMark Van Turnhout
Eindhoven University of Technology, Faculty of Biomedical Engineering, Department of Materials Technology, The Netherlands
Biorheology 42:193-207. 2005..5 and 3.5 kPa at 29 degrees C. Although the properties are clearly temperature dependent, a temperature shift in phase angle delta could not be detected, thus Time Temperature Superposition is not allowed for skeletal muscle in vitro...