Debby Gawlitta

Summary

Affiliation: Eindhoven University of Technology
Country: The Netherlands

Publications

  1. ncbi The relative contributions of compression and hypoxia to development of muscle tissue damage: an in vitro study
    Debby Gawlitta
    Department of Biomedical Engineering, Eindhoven University of Technology, WH 4 105, PO Box 513, 5600 MB, Eindhoven, The Netherlands
    Ann Biomed Eng 35:273-84. 2007
  2. pmc Evaluation of a continuous quantification method of apoptosis and necrosis in tissue cultures
    Debby Gawlitta
    Department of Biomedical Engineering, Eindhoven University of Technology, WH 4 105, P O Box 513, 5600 MB, Eindhoven, The Netherlands
    Cytotechnology 46:139-50. 2004
  3. doi The influence of serum-free culture conditions on skeletal muscle differentiation in a tissue-engineered model
    Debby Gawlitta
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Tissue Eng Part A 14:161-71. 2008
  4. ncbi Temporal differences in the influence of ischemic factors and deformation on the metabolism of engineered skeletal muscle
    Debby Gawlitta
    Dept of Biomedical Engineering, Eindhoven Univ of Technology, Eindhoven, The Netherlands
    J Appl Physiol 103:464-73. 2007
  5. doi The non-linear mechanical properties of soft engineered biological tissues determined by finite spherical indentation
    Martijn A J Cox
    Department of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, The Netherlands
    Comput Methods Biomech Biomed Engin 11:585-92. 2008
  6. doi Deep tissue injury: how deep is our understanding?
    Anke Stekelenburg
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Arch Phys Med Rehabil 89:1410-3. 2008
  7. ncbi The free diffusion of macromolecules in tissue-engineered skeletal muscle subjected to large compression strains
    Amit Gefen
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    J Biomech 41:845-53. 2008

Collaborators

Detail Information

Publications7

  1. ncbi The relative contributions of compression and hypoxia to development of muscle tissue damage: an in vitro study
    Debby Gawlitta
    Department of Biomedical Engineering, Eindhoven University of Technology, WH 4 105, PO Box 513, 5600 MB, Eindhoven, The Netherlands
    Ann Biomed Eng 35:273-84. 2007
    ..These data show that contrary to existing theories, compression can cause development of muscle damage and that hypoxia does not contribute to cell death development within 22 h in engineered muscle...
  2. pmc Evaluation of a continuous quantification method of apoptosis and necrosis in tissue cultures
    Debby Gawlitta
    Department of Biomedical Engineering, Eindhoven University of Technology, WH 4 105, P O Box 513, 5600 MB, Eindhoven, The Netherlands
    Cytotechnology 46:139-50. 2004
    ..In conclusion, the YP/PI dual staining method was found to be a powerful tool in obtaining real-time spatial information on viability in cell and tissue culture without culture disruption...
  3. doi The influence of serum-free culture conditions on skeletal muscle differentiation in a tissue-engineered model
    Debby Gawlitta
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Tissue Eng Part A 14:161-71. 2008
    ..DMI could not induce differentiation or maintain cell viability. Serum-free culture medium supplemented with DMU or DMUI accelerates and improves myoblast differentiation in engineered muscle tissue better than the gold standard HS...
  4. ncbi Temporal differences in the influence of ischemic factors and deformation on the metabolism of engineered skeletal muscle
    Debby Gawlitta
    Dept of Biomedical Engineering, Eindhoven Univ of Technology, Eindhoven, The Netherlands
    J Appl Physiol 103:464-73. 2007
    ..By contrast, nonextreme acidification and hypoxia influenced tissue metabolism, but not the development of cell death. These data provide more insight into how compression-induced factors can lead to the onset of deep tissue injury...
  5. doi The non-linear mechanical properties of soft engineered biological tissues determined by finite spherical indentation
    Martijn A J Cox
    Department of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, The Netherlands
    Comput Methods Biomech Biomed Engin 11:585-92. 2008
    ..A non-linear Neo-Hookean constitutive model is fitted to the experimental results for parameter estimation. BAMs with cells demonstrated both stiffer and more non-linear material behaviour than BAMs without cells...
  6. doi Deep tissue injury: how deep is our understanding?
    Anke Stekelenburg
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Arch Phys Med Rehabil 89:1410-3. 2008
    ..Deformation levels exceeding a threshold value can result in rapid tissue damage that may persist, whereas ischemia has a more gradual effect as a result of glucose depletion and tissue acidification...
  7. ncbi The free diffusion of macromolecules in tissue-engineered skeletal muscle subjected to large compression strains
    Amit Gefen
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    J Biomech 41:845-53. 2008
    ....