Nicholas S Macklon

Summary

Affiliation: Division of Reproductive Medicine
Country: The Netherlands

Publications

  1. ncbi request reprint Conception to ongoing pregnancy: the 'black box' of early pregnancy loss
    N S Macklon
    Centre of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus Medical Centre, The Netherlands
    Hum Reprod Update 8:333-43. 2002
  2. ncbi request reprint Mild stimulation in in vitro fertilization
    N S Macklon
    Centre for Reproductive Medicine, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Ann N Y Acad Sci 997:105-11. 2003
  3. ncbi request reprint Aspects of ovarian follicle development throughout life
    N S Macklon
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Horm Res 52:161-70. 1999
  4. ncbi request reprint Regulation of follicle development and novel approaches to ovarian stimulation for IVF
    N Smacklon
    Department of Obstetrics and Gynaecology, Erasmus University Medical Center Rotterdam, The Netherlands
    Hum Reprod Update 6:307-12. 2000
  5. ncbi request reprint Follicle-stimulating hormone and advanced follicle development in the human
    N S Macklon
    Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
    Arch Med Res 32:595-600. 2001
  6. ncbi request reprint Gonadotropin therapy for the treatment of anovulation and for ovarian hyperstimulation for IVF
    Nicholas S Macklon
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus University Medical Center Rotterdam, Dr Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands
    Mol Cell Endocrinol 186:159-61. 2002
  7. ncbi request reprint A prospective randomized comparison of sequential versus monoculture systems for in-vitro human blastocyst development
    N S Macklon
    Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Rotterdam, The Netherlands
    Hum Reprod 17:2700-5. 2002
  8. ncbi request reprint The early luteal phase administration of estrogen and progesterone does not induce premature luteolysis in normo-ovulatory women
    Nicole G M Beckers
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Eur J Endocrinol 155:355-63. 2006
  9. ncbi request reprint Nonsupplemented luteal phase characteristics after the administration of recombinant human chorionic gonadotropin, recombinant luteinizing hormone, or gonadotropin-releasing hormone (GnRH) agonist to induce final oocyte maturation in in vitro fertilizatio
    Nicole G M Beckers
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands
    J Clin Endocrinol Metab 88:4186-92. 2003
  10. ncbi request reprint First live birth after ovarian stimulation using a chimeric long-acting human recombinant follicle-stimulating hormone (FSH) agonist (recFSH-CTP) for in vitro fertilization
    Nicole G M Beckers
    Center for Reproductive Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Fertil Steril 79:621-3. 2003

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Conception to ongoing pregnancy: the 'black box' of early pregnancy loss
    N S Macklon
    Centre of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus Medical Centre, The Netherlands
    Hum Reprod Update 8:333-43. 2002
    ..In this article, the evidence and causes of preclinical or 'occult' pregnancy are reviewed, and the implications for the infertile patient are addressed...
  2. ncbi request reprint Mild stimulation in in vitro fertilization
    N S Macklon
    Centre for Reproductive Medicine, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Ann N Y Acad Sci 997:105-11. 2003
    ..Recent evidence suggests that oocyte quality after mild stimulation may be superior to that after conventional stimulation regimens...
  3. ncbi request reprint Aspects of ovarian follicle development throughout life
    N S Macklon
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Horm Res 52:161-70. 1999
    ..The menopause is preceded by a period of reduced fertility. The development of reliable and sensitive markers for ovarian ageing will be the challenge of the near future...
  4. ncbi request reprint Regulation of follicle development and novel approaches to ovarian stimulation for IVF
    N Smacklon
    Department of Obstetrics and Gynaecology, Erasmus University Medical Center Rotterdam, The Netherlands
    Hum Reprod Update 6:307-12. 2000
    ..The benefits and risks of these minimal hyperstimulation protocols require further evaluation...
  5. ncbi request reprint Follicle-stimulating hormone and advanced follicle development in the human
    N S Macklon
    Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
    Arch Med Res 32:595-600. 2001
    ..Recognition of this concept has resulted in new approaches in ovulation induction treatment and ovarian hyperstimulation therapy for in vitro fertilization (IVF)...
  6. ncbi request reprint Gonadotropin therapy for the treatment of anovulation and for ovarian hyperstimulation for IVF
    Nicholas S Macklon
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus University Medical Center Rotterdam, Dr Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands
    Mol Cell Endocrinol 186:159-61. 2002
    ..Less monitoring would be required and chances for short-term complications or long term risks may be reduced...
  7. ncbi request reprint A prospective randomized comparison of sequential versus monoculture systems for in-vitro human blastocyst development
    N S Macklon
    Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Rotterdam, The Netherlands
    Hum Reprod 17:2700-5. 2002
    ..However, their improved efficacy over monoculture systems remains to be demonstrated in prospective studies...
  8. ncbi request reprint The early luteal phase administration of estrogen and progesterone does not induce premature luteolysis in normo-ovulatory women
    Nicole G M Beckers
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Eur J Endocrinol 155:355-63. 2006
    ..In the present study, high doses of steroids are administered after the LH surge in normo-ovulatory volunteers in order to investigate whether this intervention gives rise to endocrine changes and a shortening of the luteal phase...
  9. ncbi request reprint Nonsupplemented luteal phase characteristics after the administration of recombinant human chorionic gonadotropin, recombinant luteinizing hormone, or gonadotropin-releasing hormone (GnRH) agonist to induce final oocyte maturation in in vitro fertilizatio
    Nicole G M Beckers
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands
    J Clin Endocrinol Metab 88:4186-92. 2003
    ..Hence, support of corpus luteum function remains mandatory after ovarian stimulation for IVF with GnRH antagonist cotreatment...
  10. ncbi request reprint First live birth after ovarian stimulation using a chimeric long-acting human recombinant follicle-stimulating hormone (FSH) agonist (recFSH-CTP) for in vitro fertilization
    Nicole G M Beckers
    Center for Reproductive Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Fertil Steril 79:621-3. 2003
    ..To report the first pregnancy and live birth after ovarian stimulation using a chimeric long-acting human recombinant FSH agonist (recFSH-CTP) for IVF...
  11. ncbi request reprint A case study of the applicability of a prediction model for the selection of patients undergoing in vitro fertilization for single embryo transfer in another center
    Claudine C Hunault
    Department of Public Health, Erasmus MC University, Medical Center Rotterdam, Rotterdam, The Netherlands
    Fertil Steril 87:1314-21. 2007
    ..To evaluate the application in a different fertility clinic of a prediction model for selecting IVF patients for elective single embryo transfer...
  12. ncbi request reprint A randomized comparison of two ovarian stimulation protocols with gonadotropin-releasing hormone (GnRH) antagonist cotreatment for in vitro fertilization commencing recombinant follicle-stimulating hormone on cycle day 2 or 5 with the standard long GnRH a
    Femke P Hohmann
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands
    J Clin Endocrinol Metab 88:166-73. 2003
    ..The relatively small number of oocytes obtained after mild ovarian stimulation may represent the best of the cohort in a given cycle...
  13. ncbi request reprint Women with regular menstrual cycles and a poor response to ovarian hyperstimulation for in vitro fertilization exhibit follicular phase characteristics suggestive of ovarian aging
    Nicole G M Beckers
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus Medical Center, Rotterdam, The Netherlands
    Fertil Steril 78:291-7. 2002
    ..To investigate whether follicular phase characteristics associated with ovarian aging can be observed in women of normal reproductive age, who had previously shown a poor response to ovarian hyperstimulation for IVF...
  14. ncbi request reprint FSH response-dose can be predicted in ovulation induction for normogonadotropic anovulatory infertility
    Evert J P van Santbrink
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus Medical Center, GD, The Netherlands
    Eur J Endocrinol 147:223-6. 2002
    ..To evaluate the ability of a prediction model to identify the individual starting dose of FSH for ovulation induction using a step-down regimen...
  15. ncbi request reprint A prediction model for selecting patients undergoing in vitro fertilization for elective single embryo transfer
    Claudine C Hunault
    Division of Reproductive Medicine, Department of Obstetrics and Gynecology, Erasmus University Medical Center, The, Rotterdam, Netherlands
    Fertil Steril 77:725-32. 2002
    ..Construction of a prediction model to enable the selection of patients for elective single ET...
  16. ncbi request reprint Seminal plasma cobalamin significantly correlates with sperm concentration in men undergoing IVF or ICSI procedures
    Jolanda C Boxmeer
    Department of Obstetrics and Gynecology Division of Obstetrics and Reproductive Medicine, Erasmus MC, University Medical Center, 3000 CA Rotterdam, The Netherlands
    J Androl 28:521-7. 2007
    ..These findings suggest that folate and cobalamin are transferred from the blood to the male reproductive organs and emphasize the role of cobalamin in spermatogenesis in human...
  17. ncbi request reprint Reproductive biology and IVF: ovarian stimulation and endometrial receptivity
    Paul Devroey
    Centre for Reproductive Medicine, University Hospital, Dutch Speaking Brussels Free University Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium
    Trends Endocrinol Metab 15:84-90. 2004
    ..The aim of this review is to analyse the effects of gonadotropin, GnRH-agonist and GnRH-antagonist administration on endometrial behaviour, to highlight the gaps in current knowledge and to propose areas in which research is needed...
  18. ncbi request reprint Predictors of ongoing pregnancy after single-embryo transfer following mild ovarian stimulation for IVF
    Marieke F G Verberg
    Department of Reproductive Medicine and Gynecology, University Medical Center, Utrecht, The Netherlands
    Fertil Steril 89:1159-65. 2008
    ..To develop a prognostic model for the prediction of ongoing pregnancy after single-embryo transfer (SET) following mild stimulation for IVF in women less than 38 years of age...