Affiliation: Delft University of Technology
Country: The Netherlands
- Multiscale dynamics in nucleocytoplasmic transportDAVID GRUNWALD
Delft University of Technology, Kavli Institute of Nanoscience, Department of BioNanoScience, Lorentzweg 1, 2628 CJ Delft, The Netherlands
Curr Opin Cell Biol 24:100-6. 2012..Taken together, this comprises a new paradigm in how we view import/export dynamics and emphasizes the multiscale nature of NPC-mediated cellular transport...
- A perspective of the dynamic structure of the nucleus explored at the single-molecule levelThomas Dange
Kavli Institute of Nanoscience, Department of BioNanoScience, Technical University Delft, Lorentzweg 1, 2628 CJ, Delft, The Netherlands
Chromosome Res 19:117-29. 2011..In summary, we aim to present a specific, dynamic view of nuclear cellular life based on single molecule and FCS data and provide a prospective for the future...
- Nuclear export dynamics of RNA-protein complexesDAVID GRUNWALD
Delft University of Technology, Faculty of Applied Sciences, Kavli Institute of Nanoscience, Department of BioNanoScience, 2628 CJ Delft, The Netherlands
Nature 475:333-41. 2011..This review addresses the latest studies of RNA export and presents some models for how this complex process may work...
- In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transportDAVID GRUNWALD
Kavli Institute of Nanoscience, Department of BioNanoScience, TU Delft, Lorentzweg 1, 2628 CJ Delft, The Netherlands
Nature 467:604-7. 2010..Notably, the translocation through the channel was not the rate-limiting step, mRNAs can move bi-directionally in the pore complex and not all pores are equally active...