Affiliation: Delft University of Technology
Country: The Netherlands
- The three-dimensional organization of telomeres in the nucleus of mammalian cellsTony Chih Yuan Chuang
Manitoba Institute of Cell Biology, CancerCare Manitoba, University of Manitoba, 675 McDermot Avenue, Winnipeg, MB, R3E 0V9, Canada
BMC Biol 2:12. 2004..It is, therefore, essential to analyze the 3D genome organization of the interphase nucleus in both normal and cancer cells...
- From micro to nano: recent advances in high-resolution microscopyYuval Garini
Delft University of Technology, Lorentzweg 1, 2628 CJ, Delft, The Netherlands
Curr Opin Biotechnol 16:3-12. 2005..These methods bring together old theoretical concepts such as interference with novel non-linear methods that improve spatial resolution beyond the limits that were previously assumed to be unreachable...
- Segmentation and analysis of the three-dimensional redistribution of nuclear components in human mesenchymal stem cellsBart J Vermolen
Department of Imaging Science and Technology, Delft University of Technology, Delft, The Netherlands
Cytometry A 73:816-24. 2008..We propose that the use of this new image segmentation method will contribute to a better understanding of the 3D spatial organization of the cell nucleus...
- Spectral imaging: principles and applicationsYuval Garini
Quantitative Imaging Group, Faculty of Applied Sciences, Delft University of Technology, Delft, The Netherlands
Cytometry A 69:735-47. 2006..The need to measure the spectrum at each point of the image requires combining dispersive optics with the more common imaging equipment, and introduces constrains as well...
- Electroosmotic flow analysis of a branched U-turn nanofluidic deviceGea O F Parikesit
Quantitative Imaging Group, Delft University of Technology, Lorentzweg 1, 2628 CJ, Delft, The Netherlands
Lab Chip 5:1067-74. 2005..Our results show that the deviation between measured and simulated data can be explained by the measured Brownian motion of the tracer-particles, which was not incorporated in the simulation...
- Confocal 3D DNA cytometry: assessment of required coefficient of variation by computer simulationYuval Garini
Cell Oncol 28:121-2; author reply 123. 2006
- Fourier transformed spectral bio-imaging for studying the intracellular fate of liposomesUlrich Huth
Department of Pharmaceutical Technology, Albert Ludwigs University, Freiburg, Germany
Cytometry A 57:10-21. 2004..To improve the efficiency of liposomal drug targeting systems, it is necessary to understand the mechanism of liposome uptake by the cell and to follow the intracellular fate of internalized liposomes and their contents...
- Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cellsVered Raz
Department of Molecular Cell Biology, Leiden University Medical Center, Einsteinweg 20, 2300RC Leiden, The Netherlands
J Cell Sci 119:4247-56. 2006..We suggest that during activation of the caspase-8 pathway changes in the lamina structure precede changes in heterochromatin spatial organization, and the subsequent breakdown of lamina and PML-NB...
- Alterations of centromere positions in nuclei of immortalized and malignant mouse lymphocytesRahul Sarkar
Manitoba Institute of Cell Biology, The University of Manitoba, CancerCare Manitoba, Winnipeg, Manitoba, Canada
Cytometry A 71:386-92. 2007..However, data on centromere positions during cellular transformation remain elusive. This study has focused on mouse lymphocytes and investigated the centromere positions in primary, immortalized, and tumor cells...
- Centromeres in cell division, evolution, nuclear organization and diseaseAmanda Gonçalves Dos Santos Silva
Manitoba Institute of Cell Biology, CancerCare Manitoba, University of Manitoba, Winnipeg, Manitoba, Canada
J Cell Biochem 104:2040-58. 2008..Multidisciplinary research will allow for new insights into its normal and aberrant nuclear organization and may allow for new therapeutic interventions that target events linked to centromere function and cell division...