J Damoiseaux

Summary

Country: The Netherlands

Publications

  1. doi request reprint A novel enzyme-linked immunosorbent assay using a mixture of human native and recombinant proteinase-3 significantly improves the diagnostic potential for antineutrophil cytoplasmic antibody-associated vasculitis
    J Damoiseaux
    Department of Clinical and Experimental Immunology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Ann Rheum Dis 68:228-33. 2009
  2. doi request reprint EUROPLUS ANCA BIOCHIP mosaic: PR3 and MPO antigen microdots improve the laboratory diagnostics of ANCA-associated vasculitis
    Jan Damoiseaux
    Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University Medical Centre, The Netherlands
    J Immunol Methods 348:67-73. 2009
  3. doi request reprint Autoantibody standardization in The Netherlands
    Jan Damoiseaux
    Maastricht University Medical Center, Clinical and Experimental Immunology, Maastricht, The Netherlands
    Ann N Y Acad Sci 1173:10-4. 2009
  4. doi request reprint Prevalence of anticardiolipin antibodies in patient cohorts with distinct clinical manifestations of the antiphospholipid syndrome
    Jan Damoiseaux
    Division of Clinical and Experimental Immunology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands
    Ann N Y Acad Sci 1173:146-51. 2009
  5. ncbi request reprint From ANA-screening to antigen-specificity: an EASI-survey on the daily practice in European countries
    Jan Damoiseaux
    Central Diagnostic Laboratory, Maastricht University Medical Centre, Maastricht, The Netherlands
    Clin Exp Rheumatol 32:539-46. 2014
  6. pmc Anti-nuclear antibodies in daily clinical practice: prevalence in primary, secondary, and tertiary care
    Thomas Y Avery
    Central Diagnostic Laboratory, Maastricht University Medical Centre, P Debyelaan 25, 6229 HX Maastricht, The Netherlands
    J Immunol Res 2014:401739. 2014
  7. pmc Statin use and markers of immunity in the Doetinchem cohort study
    Hilda J I de Jong
    Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands Department of Toxicogenomics, Maastricht University Medical Centre, Maastricht, the Netherlands Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 8:e77587. 2013
  8. ncbi request reprint The diagnosis and classification of the cryoglobulinemic syndrome
    Jan Damoiseaux
    Central Diagnostic Laboratory, Maastricht University Medical Center, P Debyelaan 25, 6229 HX Maastricht, The Netherlands Electronic address
    Autoimmun Rev 13:359-62. 2014
  9. doi request reprint Autoantibodies in the grocery shop: does quantity matter?
    Jan Damoiseaux
    Central Diagnostic Laboratory, Maastricht University Medical Center, P Debyelaan 25, 6229 HX, Maastricht, The Netherlands
    Immunol Res 56:413-9. 2013
  10. pmc Automatic reading of ANCA-slides: evaluation of the AKLIDES system
    Jan Damoiseaux
    Laboratory of Clinical Immunology, Maastricht University Medical Center, P Debyelaan 25, 6229 HX Maastricht, The Netherlands
    Clin Dev Immunol 2012:762874. 2012

Collaborators

Detail Information

Publications26

  1. doi request reprint A novel enzyme-linked immunosorbent assay using a mixture of human native and recombinant proteinase-3 significantly improves the diagnostic potential for antineutrophil cytoplasmic antibody-associated vasculitis
    J Damoiseaux
    Department of Clinical and Experimental Immunology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Ann Rheum Dis 68:228-33. 2009
    ..While in most patients with AAV a C-ANCA pattern is due to reactivity with proteinase-3 (PR3)-ANCA, some C-ANCA-positive sera do not react with PR3...
  2. doi request reprint EUROPLUS ANCA BIOCHIP mosaic: PR3 and MPO antigen microdots improve the laboratory diagnostics of ANCA-associated vasculitis
    Jan Damoiseaux
    Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University Medical Centre, The Netherlands
    J Immunol Methods 348:67-73. 2009
    ..The EUROPLUS system combines in one incubation the conventional cell substrates with microdots of single antigens, i.e., MPO and PR3. We evaluated the diagnostic applicability of this new system for ANCA-associated vasculitis (AAV)...
  3. doi request reprint Autoantibody standardization in The Netherlands
    Jan Damoiseaux
    Maastricht University Medical Center, Clinical and Experimental Immunology, Maastricht, The Netherlands
    Ann N Y Acad Sci 1173:10-4. 2009
    ..When comparing the already available Dutch initiatives to the international EASI goals, there appears to be a lack of harmonization in testing algorithms, and this issue is the most important topic to be addressed in the near future...
  4. doi request reprint Prevalence of anticardiolipin antibodies in patient cohorts with distinct clinical manifestations of the antiphospholipid syndrome
    Jan Damoiseaux
    Division of Clinical and Experimental Immunology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands
    Ann N Y Acad Sci 1173:146-51. 2009
    ..Therefore, there might be either a need for defining specific clinical criteria to obtain a better rational for aCLA testing or aCLA testing should be excluded from the classification criteria...
  5. ncbi request reprint From ANA-screening to antigen-specificity: an EASI-survey on the daily practice in European countries
    Jan Damoiseaux
    Central Diagnostic Laboratory, Maastricht University Medical Centre, Maastricht, The Netherlands
    Clin Exp Rheumatol 32:539-46. 2014
    ..One of the main goals of the European Autoimmunity Standardisation Initiative (EASI) is the harmonisation of test-algorithms for autoantibodies related to systemic autoimmune rheumatic diseases (SARD)...
  6. pmc Anti-nuclear antibodies in daily clinical practice: prevalence in primary, secondary, and tertiary care
    Thomas Y Avery
    Central Diagnostic Laboratory, Maastricht University Medical Centre, P Debyelaan 25, 6229 HX Maastricht, The Netherlands
    J Immunol Res 2014:401739. 2014
    ..Whether alternative approaches, that is, immunoadsorption of anti-DFS70 antibodies or implementation of anti-ENA screen assays, perform better, needs to be determined. ..
  7. pmc Statin use and markers of immunity in the Doetinchem cohort study
    Hilda J I de Jong
    Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands Department of Toxicogenomics, Maastricht University Medical Centre, Maastricht, the Netherlands Division of Pharmacoepidemiology and Clinical Pharmacology, Department of Pharmaceutical Sciences, Faculty of Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 8:e77587. 2013
    ..We postulate that the observed decreased inflammatory response during statin therapy may be important but is insufficient to induce loss of self-tolerance. ..
  8. ncbi request reprint The diagnosis and classification of the cryoglobulinemic syndrome
    Jan Damoiseaux
    Central Diagnostic Laboratory, Maastricht University Medical Center, P Debyelaan 25, 6229 HX Maastricht, The Netherlands Electronic address
    Autoimmun Rev 13:359-62. 2014
    ..These items include a restricted number of self-reported clinical history, typical clinical manifestations, and specified laboratory findings. These classification criteria await further validation in an independent patient cohort. ..
  9. doi request reprint Autoantibodies in the grocery shop: does quantity matter?
    Jan Damoiseaux
    Central Diagnostic Laboratory, Maastricht University Medical Center, P Debyelaan 25, 6229 HX, Maastricht, The Netherlands
    Immunol Res 56:413-9. 2013
    ..Obviously, if quantification of autoantibodies is performed in the laboratory, results should also be reported quantitatively together with an appropriate interpretation for the clinician...
  10. pmc Automatic reading of ANCA-slides: evaluation of the AKLIDES system
    Jan Damoiseaux
    Laboratory of Clinical Immunology, Maastricht University Medical Center, P Debyelaan 25, 6229 HX Maastricht, The Netherlands
    Clin Dev Immunol 2012:762874. 2012
    ..Distinction of C- and P-ANCA is good, but sensitivity on ethanol-fixed neutrophils needs improvement. When optimized, pattern recognition software may play an important role in AAV diagnostics...
  11. doi request reprint Autoantibody detection in bullous pemphigoid: clinical evaluation of the EUROPLUS™ Dermatology Mosaic
    Jan Damoiseaux
    Laboratory of Clinical Immunology, Maastricht University Medical Center, Maastricht, The Netherlands
    J Immunol Methods 382:76-80. 2012
    ....
  12. pmc T cells in ANCA-associated vasculitis: what can we learn from lesional versus circulating T cells?
    Benjamin Wilde
    Department of Internal Medicine, Division of Clinical and Experimental Immunology, University Hospital Maastricht, Universiteitssingel 50, PO Box 616, 6200 MD Maastricht The Netherlands
    Arthritis Res Ther 12:204. 2010
    ..Targeting the above-mentioned T cell-mediated disease mechanisms will potentially provide powerful therapeutic tools for AAV...
  13. doi request reprint Fraction of IL-10+ and IL-17+ CD8 T cells is increased in MS patients in remission and during a relapse, but is not influenced by immune modulators
    E Peelen
    School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands
    J Neuroimmunol 258:77-84. 2013
    ..We show that both Tc17 and Tc10 cell fractions are elevated in the circulation of RRMS patients in remission compared to healthy subjects and that these Tc subsets remain unaffected by current immune modulating regimens...
  14. ncbi request reprint Evaluation of the FIDIS vasculitis multiplex immunoassay for diagnosis and follow-up of ANCA-associated vasculitis and Goodpasture's disease
    J Damoiseaux
    Department of Clinical and Experimental Immunology, University Hospital Maastricht, The Netherlands
    Ann N Y Acad Sci 1109:454-63. 2007
    ..However, detection of rises in PR3-ANCA for prediction of relapses gives less optimal results when compared to capture ELISA...
  15. ncbi request reprint Higher levels of reported sun exposure, and not vitamin D status, are associated with less depressive symptoms and fatigue in multiple sclerosis
    S Knippenberg
    School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands Academic MS Center Limburg, Orbis Medical Center, Sittard, The Netherlands Department of Internal Medicine, Division of Clinical and Experimental Immunology, Maastricht University Medical Center, Maastricht, The Netherlands
    Acta Neurol Scand 129:123-31. 2014
    ..Our objective was to examine the associations between personal sun exposure and serum 25-hydroxyvitamin D (25(OH)D), and depression, anxiety, fatigue and cognition...
  16. ncbi request reprint Type II cryoglobulinemia is not associated with hepatitis C infection: the Dutch experience
    J W Cohen Tervaert
    Department of Clinical and Experimental Immunology, University Hospital Maastricht, P Debyelaan 25, 6229 HX Maastricht, The Netherlands
    Ann N Y Acad Sci 1107:251-8. 2007
    ..A search for yet unknown etiological factors is clearly needed in these patients, who frequently have severe renal involvement warranting aggressive immunosuppressive therapy...
  17. ncbi request reprint Regulatory B cells in ANCA-associated vasculitis
    B Wilde
    Department of Internal Medicine, Division of Clinical and Experimental Immunology, University Hospital Maastricht, Maastricht, The Netherlands
    Ann Rheum Dis 72:1416-9. 2013
    ..In the present study, we investigated the role of Breg in antineutrophil cytoplasmic antibodies-associated vasculitis (AAV)...
  18. ncbi request reprint Induction of endothelial cell apoptosis by IgG antibodies from SLE patients with nephropathy: a potential role for anti-endothelial cell antibodies
    Pieter van Paassen
    Division of Clinical and Experimental Immunology, Department of Internal Medicine, CARIM, Academic Hospital and University of Maastricht, Maastricht, The Netherlands
    Ann N Y Acad Sci 1108:147-56. 2007
    ..Our data show that antibodies other than anti-HSP60 are also involved in apoptosis induction. The results are discussed in the context of recent findings on the role of AECA in endothelial cell apoptosis and renal vasculopathy in SLE...
  19. ncbi request reprint Cross-reactivity of IgM and IgG anticardiolipin antibodies with oxidized-low density lipoproteins
    J Damoiseaux
    Department of Clinical and Experimental Immunology, University Hospital Maastricht, P O Box 5800, 6202 AZ Maastricht, The Netherlands
    Ann N Y Acad Sci 1050:163-9. 2005
    ..Therefore, identification of both antibodies may be relevant for determination of the prognosis of accelerated atherosclerosis in SLE patients...
  20. doi request reprint The therapeutic potential of targeting B cells and anti-oxLDL antibodies in atherosclerosis
    M van Leeuwen
    Department of Internal Medicine, Section Clinical and Experimental Immunology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, 6200 MD Maastricht, The Netherlands
    Autoimmun Rev 9:53-7. 2009
    ..Therefore, the establishment of effective therapy, targeting B cells or anti-oxLDL antibodies, warrants further research to unravel these opposite effects...
  21. doi request reprint Relatively high serum vitamin D levels do not impair the antibody response to encapsulated bacteria
    E Peelen
    School for Mental Health and Neuroscience, Maastricht University Medical Center, Universiteitssingel 50, room 5 302, PO Box 616, 6200 MD Maastricht, The Netherlands
    Eur J Clin Microbiol Infect Dis 32:61-9. 2013
    ..These data indicate that a relatively high vitamin D status does not seem to hamper an adequate antibody response upon infection or vaccination, suggesting that vitamin D, in this setting, is not immunosuppressive...
  22. ncbi request reprint Vitamin D status in patients with MS is negatively correlated with depression, but not with fatigue
    S Knippenberg
    School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands
    Acta Neurol Scand 124:171-5. 2011
    ..Depressive symptoms and fatigue are frequent and disabling symptoms of multiple sclerosis (MS). Depression and fatigue have been associated with a poor vitamin D status, and a poor vitamin D status is often found in MS...
  23. ncbi request reprint Evaluation of a novel line-blot immunoassay for the detection of antibodies to extractable nuclear antigens
    J Damoiseaux
    Department of Clinical and Experimental Immunology, University Hospital Maastricht, P O Box 5800, 6202 AZ Maastricht, The Netherlands
    Ann N Y Acad Sci 1050:340-7. 2005
    ..The clinical relevance of the latter finding remains to be determined. In conclusion, LIA is suitable for routine evaluation of autoantibodies to extractable nuclear antigens...
  24. ncbi request reprint Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis
    J Smolders
    School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Mult Scler 14:1220-4. 2008
    ..We investigated the association between serum levels of 25(OH)D and 1,25-dihydroxyvitamin D (1,25(OH)2D), the biologically active metabolite, and clinical MS severity as expressed by EDSS-score and relapse rate...
  25. ncbi request reprint Evaluation of a rapid one-step immunochromatographic test and two immunoenzymatic assays for the detection of anti-Treponema pallidum antibodies
    L van Dommelen
    Medical Microbiology, Maastricht Infection Centre, University Hospital Maastricht, PO Box 5800, 6200 AZ Maastricht, The Netherlands
    Sex Transm Infect 84:292-6. 2008
    ..Because of the drawbacks in current diagnostic procedures, ie, long turnaround time, the need is felt for a rapid and simple test that can potentially be performed on whole blood...